Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

Authors: Kelly, Tanika N., Sun, Xiao, He, Karen Y., Brown, Michael R., Taliun, Sarah A. Gagliano, Hellwege, Jacklyn N., Irvin, Marguerite R., Mi, Xuenan, Brody, Jennifer A., Franceschini, Nora, Guo, Xiuqing, Hwang, Shih-Jen, de Vries, Paul S., Gao, Yan, Moscati, Arden, Nadkarni, Girish N., Yanek, Lisa R., Elfassy, Tali, Smith, Jennifer A., Chung, Ren-Hua, Beitelshees, Amber L., Patki, Amit, Aslibekyan, Stella, Blobner, Brandon M., Peralta, Juan M., Assimes, Themistocles L., Palmas, Walter R., Liu, Chunyu, Bress, Adam P., Huang, Zhijie, Becker, Lewis C., Hwa, Chii-Min, O'Connell, Jeffrey R., Carlson, Jenna C., Warren, Helen R., Das, Sayantan, Giri, Ayush, Martin, Lisa W., Craig Johnson, W., Fox, Ervin R., Bottinger, Erwin P., Razavi, Alexander C., Vaidya, Dhananjay, Chuang, Lee-Ming, Chang, Yen-Pei C., Naseri, Take, Jain, Deepti, Kang, Hyun Min, Hung, Adriana M., Srinivasasainagendra, Vinodh, Snively, Beverly M., Gu, Dongfeng, Montasser, May E., Reupena, Muagututi'a Sefuiva, Heavner, Benjamin D., LeFaive, Jonathon, Hixson, James E., Rice, Kenneth M., Wang, Fei Fei, Nielsen, Jonas B., Huang, Jianfeng, Khan, Alyna T., Zhou, Wei, Nierenberg, Jovia L., Laurie, Cathy C., Armstrong, Nicole D., Shi, Mengyao, Pan, Yang, Stilp, Adrienne M., Emery, Leslie, Wong, Quenna, Hawley, Nicola L., Minster, Ryan L., Curran, Joanne E., Munroe, Patricia B., Weeks, Daniel E., North, Kari E., Tracy, Russell P., Kenny, Eimear E., Shimbo, Daichi, Chakravarti, Aravinda, Rich, Stephen S., Reiner, Alex P., Blangero, John, Redline, Susan, Mitchell, Braxton D., Rao, Dabeeru C., Ida Chen, Yii-Der, Kardia, Sharon L.R., Kaplan, Robert C., Mathias, Rasika A., He, Jiang, Psaty, Bruce M., Fornage, Myriam, Loos, Ruth J.F., Correa, Adolfo, Boerwinkle, Eric, Rotter, Jerome I., Kooperberg, Charles, Edwards, Todd L., Abecasis, Gonçalo R., Zhu, Xiaofeng, Levy, Daniel, Arnett, Donna K., Morrison, Alanna C.

Source: Hypertension. 79(8):1656-1667

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172924223.0x000001&indx=1&recIds=ETOCvdc_100172924223.0x000001

Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

Authors: Sun, Daokun, Richard, Melissa A., Musani, Solomon K., Sung, Yun Ju, Winkler, Thomas W., Schwander, Karen, Chai, Jin Fang, Guo, Xiuqing, Kilpeläinen, Tuomas O., Vojinovic, Dina, Aschard, Hugues, Bartz, Traci M., Bielak, Lawrence F., Brown, Michael R., Chitrala, Kumaraswamy, Hartwig, Fernando P., Horimoto, Andrea R.V.R., Liu, Yongmei, Manning, Alisa K., Noordam, Raymond, Smith, Albert V., Harris, Sarah E., Kühnel, Brigitte, Lyytikäinen, Leo-Pekka, Nolte, Ilja M., Rauramaa, Rainer, van der Most, Peter J., Wang, Rujia, Ware, Erin B., Weiss, Stefan, Wen, Wanqing, Yanek, Lisa R., Arking, Dan E., Arnett, Donna K., Barac, Ana, Boerwinkle, Eric, Broeckel, Ulrich, Chakravarti, Aravinda, Chen, Yii-Der Ida, Cupples, L. Adrienne, Davigulus, Martha L., de las Fuentes, Lisa, de Mutsert, Renée, de Vries, Paul S., Delaney, Joseph A.C., Diez Roux, Ana V., Dörr, Marcus, Faul, Jessica D., Fretts, Amanda M., Gallo, Linda C., Grabe, Hans Jörgen, Gu, C. Charles, Harris, Tamara B., Hartman, Catharina C.A., Heikkinen, Sami, Ikram, M. Arfan, Isasi, Carmen, Johnson, W. Craig, Jonas, Jost Bruno, Kaplan, Robert C., Komulainen, Pirjo, Krieger, Jose E., Levy, Daniel, Liu, Jianjun, Lohman, Kurt, Luik, Annemarie I., Martin, Lisa W., Meitinger, Thomas, Milaneschi, Yuri, O’Connell, Jeff R., Palmas, Walter R., Peters, Annette, Peyser, Patricia A., Pulkki-Råback, Laura, Raffel, Leslie J., Reiner, Alex P., Rice, Kenneth, Robinson, Jennifer G., Rosendaal, Frits R., Schmidt, Carsten Oliver, Schreiner, Pamela J., Schwettmann, Lars, Shikany, James M., Shu, Xiao-ou, Sidney, Stephen, Sims, Mario, Smith, Jennifer A., Sotoodehnia, Nona, Strauch, Konstantin, Tai, E. Shyong, Taylor, Kent D., Uitterlinden, André G., van Duijn, Cornelia M., Waldenberger, Melanie, Wee, Hwee-Lin, Wei, Wen-Bin, Wilson, Gregory, Xuan, Deng, Yao, Jie, Zeng, Donglin, Zhao, Wei, Zhu, Xiaofeng, Zonderman, Alan B., Becker, Diane M., Deary, Ian J., Gieger, Christian, Lakka, Timo A., Lehtimäki, Terho, North, Kari E., Oldehinkel, Albertine J., Penninx, Brenda W.J.H., Snieder, Harold, Wang, Ya-Xing, Weir, David R., Zheng, Wei, Evans, Michele K., Gauderman, W. James, Gudnason, Vilmundur, Horta, Bernardo L., Liu, Ching-Ti, Mook-Kanamori, Dennis O., Morrison, Alanna C., Pereira, Alexandre C., Psaty, Bruce M., Amin, Najaf, Fox, Ervin R., Kooperberg, Charles, Sim, Xueling, Bierut, Laura, Rotter, Jerome I., Kardia, Sharon L.R., Franceschini, Nora, Rao, Dabeeru C., Fornage, Myriam

Source: In Human Genetics and Genomics Advances 14 January 2021 2(1)

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Authors: Sung, Yun J., Winkler, Thomas W., de las Fuentes, Lisa, Bentley, Amy R., Brown, Michael R., Kraja, Aldi T., Schwander, Karen, Ntalla, Ioanna, Guo, Xiuqing, Franceschini, Nora, Lu, Yingchang, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Marten, Jonathan, Musani, Solomon K., Li, Changwei, Feitosa, Mary F., Kilpeläinen, Tuomas O., Richard, Melissa A., Noordam, Raymond, Aslibekyan, Stella, Aschard, Hugues, Bartz, Traci M., Dorajoo, Rajkumar, Liu, Yongmei, Manning, Alisa K., Rankinen, Tuomo, Smith, Albert Vernon, Tajuddin, Salman M., Tayo, Bamidele O., Warren, Helen R., Zhao, Wei, Zhou, Yanhua, Matoba, Nana, Sofer, Tamar, Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Gandin, Ilaria, Gao, Chuan, Giulianini, Franco, Goel, Anuj, Harris, Sarah E., Hartwig, Fernando Pires, Horimoto, Andrea R.V.R., Hsu, Fang-Chi, Jackson, Anne U., Kähönen, Mika, Kasturiratne, Anuradhani, Kühnel, Brigitte, Leander, Karin, Lee, Wen-Jane, Lin, Keng-Hung, ’an Luan, Jian, McKenzie, Colin A., Meian, He, Nelson, Christopher P., Rauramaa, Rainer, Schupf, Nicole, Scott, Robert A., Sheu, Wayne H.H., Stančáková, Alena, Takeuchi, Fumihiko, van der Most, Peter J., Varga, Tibor V., Wang, Heming, Wang, Yajuan, Ware, Erin B., Weiss, Stefan, Wen, Wanqing, Yanek, Lisa R., Zhang, Weihua, Zhao, Jing Hua, Afaq, Saima, Alfred, Tamuno, Amin, Najaf, Arking, Dan, Aung, Tin, Barr, R. Graham, Bielak, Lawrence F., Boerwinkle, Eric, Bottinger, Erwin P., Braund, Peter S., Brody, Jennifer A., Broeckel, Ulrich, Cabrera, Claudia P., Cade, Brian, Caizheng, Yu, Campbell, Archie, Canouil, Mickaël, Chakravarti, Aravinda, Chauhan, Ganesh, Christensen, Kaare, Cocca, Massimiliano, Collins, Francis S., Connell, John M., de Mutsert, Renée, de Silva, H. Janaka, Debette, Stephanie, Dörr, Marcus, Duan, Qing, Eaton, Charles B., Ehret, Georg, Evangelou, Evangelos, Faul, Jessica D., Fisher, Virginia A., Forouhi, Nita G., Franco, Oscar H., Friedlander, Yechiel, Gao, He, Gigante, Bruna, Graff, Misa, Gu, C. Charles, Gu, Dongfeng, Gupta, Preeti, Hagenaars, Saskia P., Harris, Tamara B., He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hirata, Makoto, Hofman, Albert, Howard, Barbara V., Hunt, Steven, Irvin, Marguerite R., Jia, Yucheng, Joehanes, Roby, Justice, Anne E., Katsuya, Tomohiro, Kaufman, Joel, Kerrison, Nicola D., Khor, Chiea Chuen, Koh, Woon-Puay, Koistinen, Heikki A., Komulainen, Pirjo, Kooperberg, Charles, Krieger, Jose E., Kubo, Michiaki, Kuusisto, Johanna, Langefeld, Carl D., Langenberg, Claudia, Launer, Lenore J., Lehne, Benjamin, Lewis, Cora E., Li, Yize, Lim, Sing Hui, Lin, Shiow, Liu, Ching-Ti, Liu, Jianjun, Liu, Jingmin, Liu, Kiang, Liu, Yeheng, Loh, Marie, Lohman, Kurt K., Long, Jirong, Louie, Tin, Mägi, Reedik, Mahajan, Anubha, Meitinger, Thomas, Metspalu, Andres, Milani, Lili, Momozawa, Yukihide, Morris, Andrew P., Mosley, Thomas H., Jr., Munson, Peter, Murray, Alison D., Nalls, Mike A., Nasri, Ubaydah, Norris, Jill M., North, Kari, Ogunniyi, Adesola, Padmanabhan, Sandosh, Palmas, Walter R., Palmer, Nicholette D., Pankow, James S., Pedersen, Nancy L., Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Raitakari, Olli T., Renström, Frida, Rice, Treva K., Ridker, Paul M., Robino, Antonietta, Robinson, Jennifer G., Rose, Lynda M., Rudan, Igor, Sabanayagam, Charumathi, Salako, Babatunde L., Sandow, Kevin, Schmidt, Carsten O., Schreiner, Pamela J., Scott, William R., Seshadri, Sudha, Sever, Peter, Sitlani, Colleen M., Smith, Jennifer A., Snieder, Harold, Starr, John M., Strauch, Konstantin, Tang, Hua, Taylor, Kent D., Teo, Yik Ying, Tham, Yih Chung, Uitterlinden, André G., Waldenberger, Melanie, Wang, Lihua, Wang, Ya X., Wei, Wen Bin, Williams, Christine, Wilson, Gregory, Wojczynski, Mary K., Yao, Jie, Yuan, Jian-Min, Zonderman, Alan B., Becker, Diane M., Boehnke, Michael, Bowden, Donald W., Chambers, John C., Chen, Yii-Der Ida, de Faire, Ulf, Deary, Ian J., Esko, Tõnu, Farrall, Martin, Forrester, Terrence, Franks, Paul W., Freedman, Barry I., Froguel, Philippe, Gasparini, Paolo, Gieger, Christian, Horta, Bernardo Lessa, Hung, Yi-Jen, Jonas, Jost B., Kato, Norihiro, Kooner, Jaspal S., Laakso, Markku, Lehtimäki, Terho, Liang, Kae-Woei, Magnusson, Patrik K.E., Newman, Anne B., Oldehinkel, Albertine J., Pereira, Alexandre C., Redline, Susan, Rettig, Rainer, Samani, Nilesh J., Scott, James, Shu, Xiao-Ou, van der Harst, Pim, Wagenknecht, Lynne E., Wareham, Nicholas J., Watkins, Hugh, Weir, David R., Wickremasinghe, Ananda R., Wu, Tangchun, Zheng, Wei, Kamatani, Yoichiro, Laurie, Cathy C., Bouchard, Claude, Cooper, Richard S., Evans, Michele K., Gudnason, Vilmundur, Kardia, Sharon L.R., Kritchevsky, Stephen B., Levy, Daniel, O’Connell, Jeff R., Psaty, Bruce M., van Dam, Rob M., Sims, Mario, Arnett, Donna K., Mook-Kanamori, Dennis O., Kelly, Tanika N., Fox, Ervin R., Hayward, Caroline, Fornage, Myriam, Rotimi, Charles N., Province, Michael A., van Duijn, Cornelia M., Tai, E. Shyong, Wong, Tien Yin, Loos, Ruth J.F., Reiner, Alex P., Rotter, Jerome I., Zhu, Xiaofeng, Bierut, Laura J., Gauderman, W. James, Caulfield, Mark J., Elliott, Paul, Rice, Kenneth, Munroe, Patricia B., Morrison, Alanna C., Cupples, L. Adrienne, Rao, Dabeeru C., Chasman, Daniel I.

Source: In The American Journal of Human Genetics 1 March 2018 102(3):375-400

Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos

Authors: Sofer, Tamar, Emery, Leslie, Jain, Deepti, Ellis, Alicia M., Laurie, Cathy C., Allison, Matthew A., Lee, Jiwon, Kurniansyah, Nuzulul, Kerr, Kathleen F., González, Hector M., Tarraf, Wassim, Criqui, Michael H., Lange, Leslie A., Palmas, Walter R., Franceschini, Nora, Wassel, Christina L.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131453544.0x000001&indx=1&recIds=ETOCvdc_100131453544.0x000001

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

Authors: de las Fuentes, Lisa, Sung, Yun Ju, Noordam, Raymond, Winkler, Thomas, Feitosa, Mary F., Schwander, Karen, Bentley, Amy R., Brown, Michael R., Guo, Xiuqing, Manning, Alisa, Chasman, Daniel I., Aschard, Hugues, Bartz, Traci M., Bielak, Lawrence F., Campbell, Archie, Cheng, Ching-Yu, Dorajoo, Rajkumar, Hartwig, Fernando P., Horimoto, A. R. V. R., Li, Changwei, Li-Gao, Ruifang, Liu, Yongmei, Marten, Jonathan, Musani, Solomon K., Ntalla, Ioanna, Rankinen, Tuomo, Richard, Melissa, Sim, Xueling, Smith, Albert V., Tajuddin, Salman M., Tayo, Bamidele O., Vojinovic, Dina, Warren, Helen R., Xuan, Deng, Alver, Maris, Boissel, Mathilde, Chai, Jin-Fang, Chen, Xu, Christensen, Kaare, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Girotto, Giorgia, Harris, Sarah E., He, Meian, Hsu, Fang-Chi, Kühnel, Brigitte, Laguzzi, Federica, Li, Xiaoyin, Lyytikäinen, Leo-Pekka, Nolte, Ilja M., Poveda, Alaitz, Rauramaa, Rainer, Riaz, Muhammad, Rueedi, Rico, Shu, Xiao-ou, Snieder, Harold, Sofer, Tamar, Takeuchi, Fumihiko, Verweij, Niek, Ware, Erin B., Weiss, Stefan, Yanek, Lisa R., Amin, Najaf, Arking, Dan E., Arnett, Donna K., Bergmann, Sven, Boerwinkle, Eric, Brody, Jennifer A., Broeckel, Ulrich, Brumat, Marco, Burke, Gregory, Cabrera, Claudia P., Canouil, Mickaël, Chee, Miao Li, Chen, Yii-Der Ida, Cocca, Massimiliano, Connell, John, de Silva, H. Janaka, de Vries, Paul S., Eiriksdottir, Gudny, Faul, Jessica D., Fisher, Virginia, Forrester, Terrence, Fox, Ervin F., Friedlander, Yechiel, Gao, He, Gigante, Bruna, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara B., He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven, Ikram, M. Arfan, Irvin, Marguerite R., Kähönen, Mika, Kavousi, Maryam, Khor, Chiea Chuen, Kilpeläinen, Tuomas O., Koh, Woon-Puay, Komulainen, Pirjo, Kraja, Aldi T., Krieger, J. E., Langefeld, Carl D., Li, Yize, Liang, Jingjing, Liewald, David C. M., Liu, Ching-Ti, Liu, Jianjun, Lohman, Kurt K., Mägi, Reedik, McKenzie, Colin A., Meitinger, Thomas, Metspalu, Andres, Milaneschi, Yuri, Milani, Lili, Mook-Kanamori, Dennis O., Nalls, Mike A., Nelson, Christopher P., Norris, Jill M., O’Connell, Jeff, Ogunniyi, Adesola, Padmanabhan, Sandosh, Palmer, Nicholette D., Pedersen, Nancy L., Perls, Thomas, Peters, Annette, Petersmann, Astrid, Peyser, Patricia A., Polasek, Ozren, Porteous, David J., Raffel, Leslie J., Rice, Treva K., Rotter, Jerome I., Rudan, Igor, Rueda-Ochoa, Oscar-Leonel, Sabanayagam, Charumathi, Salako, Babatunde L., Schreiner, Pamela J., Shikany, James M., Sidney, Stephen S., Sims, Mario, Sitlani, Colleen M., Smith, Jennifer A., Starr, John M., Strauch, Konstantin, Swertz, Morris A., Teumer, Alexander, Tham, Yih Chung, Uitterlinden, André G., Vaidya, Dhananjay, van der Ende, M. Yldau, Waldenberger, Melanie, Wang, Lihua, Wang, Ya-Xing, Wei, Wen-Bin, Weir, David R., Wen, Wanqing, Yao, Jie, Yu, Bing, Yu, Caizheng, Yuan, Jian-Min, Zhao, Wei, Zonderman, Alan B., Becker, Diane M., Bowden, Donald W., Deary, Ian J., Dörr, Marcus, Esko, Tõnu, Freedman, Barry I., Froguel, Philippe, Gasparini, Paolo, Gieger, Christian, Jonas, Jost Bruno, Kammerer, Candace M., Kato, Norihiro, Lakka, Timo A., Leander, Karin, Lehtimäki, Terho, Magnusson, Patrik K. E., Marques-Vidal, Pedro, Penninx, Brenda W. J. H., Samani, Nilesh J., van der Harst, Pim, Wagenknecht, Lynne E., Wu, Tangchun, Zheng, Wei, Zhu, Xiaofeng, Bouchard, Claude, Cooper, Richard S., Correa, Adolfo, Evans, Michele K., Gudnason, Vilmundur, Hayward, Caroline, Horta, Bernardo L., Kelly, Tanika N., Kritchevsky, Stephen B., Levy, Daniel, Palmas, Walter R., Pereira, A. C., Province, Michael M., Psaty, Bruce M., Ridker, Paul M., Rotimi, Charles N., Tai, E. Shyong, van Dam, Rob M., van Duijn, Cornelia M., Wong, Tien Yin, Rice, Kenneth, Gauderman, W. James, Morrison, Alanna C., North, Kari E., Kardia, Sharon L. R., Caulfield, Mark J., Elliott, Paul, Munroe, Patricia B., Franks, Paul W., Rao, Dabeeru C., Fornage, Myriam

Source: Molecular Psychiatry; June 2021, Vol. 26 Issue: 6 p2111-2125, 15p

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