Suboptimal outcomes of sorafenib as a second-line treatment after atezolizumab-bevacizumab for unresectable hepatocellular carcinoma

Authors: Tovoli, Francesco, Pallotta, Dante Pio, Vivaldi, Caterina, Campani, Claudia, Federico, Piera, Palloni, Andrea, Dalbeni, Andrea, Soldà, Caterina, Lani, Lorenzo, Svegliati-Baroni, Gianluca, Garajova, Ingrid, Ielasi, Luca, De Lorenzo, Stefania, Granito, Alessandro, Stefanini, Bernardo, Masi, Gianluca, Marra, Fabio, Lonardi, Sara, Brandi, Giovanni, Daniele, Bruno, Auriemma, Alessandra, Schiadà, Laura, Chen, Rusi, Piscaglia, Fabio

Source: In Digestive and Liver Disease December 2024 56(12):2079-2084

Pemigatinib for patients with previously treated, locally advanced or metastatic cholangiocarcinoma harboring FGFR2 fusions or rearrangements: A joint analysis of the French PEMI-BIL and Italian PEMI-REAL cohort studies

Authors: Parisi, Alessandro, Delaunay, Blandine, Pinterpe, Giada, Hollebecque, Antoine, Blanc, Jean Frederic, Bouattour, Mohamed, Assenat, Eric, Ben Abdelghani, Meher, Sarabi, Matthieu, Niger, Monica, Vivaldi, Caterina, Mandalà, Mario, Palloni, Andrea, Bensi, Maria, Garattini, Silvio Ken, Tougeron, David, Combe, Pierre, Salati, Massimiliano, Rimini, Margherita, Cella, Chiara Alessandra, Tucci, Marco, Diana, Anna, Mori, Elena, Longarini, Raffaella, Artru, Pascal, Roth, Gael, Evesque, Ludovic, Vienne, Agathe, Turpin, Anthony, Hiret, Sandrine, Bourgeois, Vincent, Herve, Camille, Paulon, Rodolphe, Stacoffe, Marion, Malka, David, Neuzillet, Cindy, Edeline, Julien, Lievre, Astrid, Guimbaud, Rosine, Chapda, Marie Christelle Pajiep, Rimassa, Lorenza, Giampieri, Riccardo, Valle, Juan, Berardi, Rossana, Fares, Nadim

Source: In European Journal of Cancer March 2024 200

Case Report: Long lasting response with TKI for combined hepatocellular-cholangiocarcinoma.

Authors: Deiana, Chiara, Palloni, Andrea, Mosca, Mirta, Vasuri, Francesco, Chillotti, Stefano, Tavolari, Simona, De Biase, Dario, Frega, Giorgio, Giovannetti, Elisa, Brandi, Giovanni

Source: Frontiers in Oncology; 2025, p1-7, 7p

Subject Terms: PROTEIN-tyrosine kinase inhibitors, CLINICAL trials, GENOMICS, LIVER cancer, HEPATOCELLULAR carcinoma

The use of comprehensive complication Index® in pancreatic surgery: a comparison with the Clavien-Dindo system in a high volume center

Authors: Ricci, Claudio, Ingaldi, Carlo, Grego, Davide G., Alberici, Laura, De Raffele, Emilio, Pagano, Nico, Mosconi, Cristina, Di Marco, Mariacristina, Palloni, Andrea, Brandi, Giovanni, Minni, Francesco, Casadei, Riccardo

Source: In HPB April 2021 23(4):618-624

Viral Hepatitis in Western Patients with Advanced Intrahepatic Cholangiocarcinoma: Retrospective Assessment of Prevalence, Prognostic and Predictive Significance.

Authors: Filippi, Roberto, Brandi, Giovanni, Casadei-Gardini, Andrea, Leone, Francesco, Silvestris, Nicola, Satolli, Maria Antonietta, Salani, Francesca, Sperti, Elisa, Lutrino, Stefania Eufemia, Aprile, Giuseppe, Santini, Daniele, Scartozzi, Mario, Faloppi, Luca, Palloni, Andrea, Deserti, Marzia, Tavolari, Simona, Rimini, Margherita, Brunetti, Oronzo, Spadi, Rosella, Ilaria, Depetris

Source: Cancer Investigation; Jan2025, Vol. 43 Issue 1, p59-69, 11p

Subject Terms: RISK assessment, BILE duct tumors, VIRAL hepatitis, CHOLANGIOCARCINOMA, RETROSPECTIVE studies, INFLAMMATION, BIOMARKERS, DISEASE progression, DISEASE risk factors, DISEASE complications

Treatment Sequencing and Independent Outcomes of First- and Second-Line Chemotherapy in a Retrospective Series of Patients with Biliary Tract Cancer.

Authors: Frega, Giorgio¹ (AUTHOR) giorgio.frega@ior.it, Palloni, Andrea² (AUTHOR) andrea.palloni@aosp.bo.it, Deiana, Chiara² (AUTHOR) chiarad.kw@gmail.com, Rizzo, Alessandro³ (AUTHOR) rizzo.alessandro179@gmail.com, Ricci, Angela Dalia⁴ (AUTHOR) dalia.ricci@gmail.com, Brandi, Giovanni² (AUTHOR) giovanni.brandi@unibo.it

Source: Journal of Clinical Medicine. Dec2024, Vol. 13 Issue 23, p7262. 10p.

Subject Terms: *CANCER chemotherapy, *PATIENTS' attitudes, *CISPLATIN, *SEQUENTIAL analysis, BILIARY tract cancer

Chemoradiation of locally advanced biliary cancer: A PRISMA‐compliant systematic review.

Authors: Bisello, Silvia, Malizia, Claudio, Mammini, Filippo, Galietta, Erika, Medici, Federica, Mattiucci, Gian Carlo, Cellini, Francesco, Palloni, Andrea, Tagliaferri, Luca, Macchia, Gabriella, Deodato, Francesco, Cilla, Savino, Brandi, Giovanni, Arcelli, Alessandra, Morganti, Alessio G.

Source: Cancer Medicine; Dec2024, Vol. 13 Issue 23, p1-16, 16p

Subject Terms: BILIARY tract cancer, GALLBLADDER cancer, OVERALL survival, CRIME & the press, RADIOISOTOPE brachytherapy

The Potential Role of Adjuvant Chemoradiotherapy in Patients with Microscopically Positive (R1) Surgical Margins after Resection of Cholangiocarcinoma.

Authors: Palloni, Andrea¹ (AUTHOR) andrea.palloni@aosp.bo.it, Bisello, Silvia² (AUTHOR), Maggio, Ilaria³ (AUTHOR), Massucci, Maria¹ (AUTHOR), Galuppi, Andrea² (AUTHOR), Di Federico, Alessandro^1,4 (AUTHOR), Rizzo, Alessandro⁵ (AUTHOR), Ricci, Angela Dalia⁶ (AUTHOR), Siepe, Giambattista² (AUTHOR), Morganti, Alessio Giuseppe² (AUTHOR), Brandi, Giovanni^1,4 (AUTHOR) giovanni.brandi@unibo.it, Frega, Giorgio⁷ (AUTHOR) giorgio.frega@ior.it

Source: Current Oncology. May2023, Vol. 30 Issue 5, p4754-4766. 13p. 1 Diagram, 2 Charts, 2 Graphs.

Subject Terms: *SURGICAL margin, *CHOLANGIOCARCINOMA, *CHEMORADIOTHERAPY, *SURVIVAL rate, *OVERALL survival, BILIARY tract cancer

Prediction of survival with second-line therapy in biliary tract cancer: Actualisation of the AGEO CT2BIL cohort and European multicentre validations

Authors: Evesque, Ludovic, Heurgué, Alexandra, Desramé, Jérôme, Lecomte, Thierry, Cacheux, Wulfran, Bachet, Jean-Baptiste, Phelip, Jean-Marc, Hautefeuille, Vincent, Hammoudi, Nassim, Mary, Florence, Locher, Christophe, Bidault-Thirot, Anne, Marthey, Lysiane, Touchefeu, Yann, Moulin, Valérie, Zaanan, Aziz, Taïeb, Julien, Casagrande, Mariaelena, Murgioni, Sabina, Santini, Daniele, Fornaro, Lorenzo, Montagnani, Francesco, Leone, Francesco, Faloppi, Luca, Giommoni, Elisa, Lutrino, Stefania Eufemia, Palloni, Andrea, Brunetti, Oronzo, Bergamo, Francesca, Vasile, Enrico, Malka, David, Propper, David, Neuzillet, Cindy, Casadei Gardini, Andrea, Brieau, Bertrand, Vivaldi, Caterina, Smolenschi, Cristina, Brandi, Giovanni, Tougeron, David, Filippi, Roberto, Vienot, Angélique, Silvestris, Nicola, Pointet, Anne-Laure, Lonardi, Sara, Rousseau, Benoît, Scartozzi, Mario, Dahan, Laetitia, Aprile, Giuseppe, Boussaha, Tarek, Crusz, Shantini M., Le Sourd, Samuel, Meurisse, Aurélia, Lièvre, Astrid, Vernerey, Dewi

Source: In European Journal of Cancer April 2019 111:94-106

Decreasing Albumin mRNA Expression in Cholangiocarcinomas along the Bile Duct Tree.

Authors: Albertini, Elisa, Chillotti, Stefano, Monti, Giada, Malvi, Deborah, Deserti, Marzia, Degiovanni, Alessio, Palloni, Andrea, Tavolari, Simona, Brandi, Giovanni, D'Errico, Antonia, Vasuri, Francesco

Source: Pathobiology; 2024, Vol. 91 Issue 5, p338-344, 7p

Activated FGFR2 signalling as a biomarker for selection of intrahepatic cholangiocarcinoma patients candidate to FGFR targeted therapies.

Authors: Brandi, Giovanni, Relli, Valeria, Deserti, Marzia, Palloni, Andrea, Indio, Valentina, Astolfi, Annalisa, Serravalle, Salvatore, Mattiaccio, Alessandro, Vasuri, Francesco, Malvi, Deborah, Deiana, Chiara, Pantaleo, Maria Abbondanza, Cescon, Matteo, Rizzo, Alessandro, Katoh, Masaru, Tavolari, Simona

Source: Scientific Reports; 2/7/2024, Vol. 14 Issue 1, p1-13, 13p

Improvements in Systemic Therapies for Advanced Malignant Mesothelioma.

Authors: Deiana, Chiara, Fabbri, Francesca, Tavolari, Simona, Palloni, Andrea, Brandi, Giovanni

Source: International Journal of Molecular Sciences; Jul2023, Vol. 24 Issue 13, p10415, 22p

Subject Terms: MESOTHELIOMA, SURVIVAL rate, SURVIVAL analysis (Biometry), IMMUNOTHERAPY

Are FGFR and IDH1-2 alterations a positive prognostic factor in intrahepatic cholangiocarcinoma? An unresolved issue.

Authors: Brandi, Giovanni, Deiana, Chiara, Galvani, Linda, Palloni, Andrea, Ricci, Angela Dalia, Rizzo, Alessandro, Tavolari, Simona

Source: Frontiers in Oncology; 2023, p1-10, 10p

Subject Terms: CHOLANGIOCARCINOMA, PROGNOSIS, OVERALL survival, EXPERIMENTAL design

THU-472-YI Sorafenib as a second-line treatment after failure of Atezolizumab/Bevacizumab

Authors: Tovoli, Francesco, Boe, Maria, Vivaldi, Caterina, Federico, Piera, Palloni, Andrea, Dalbeni, Andrea, Soldà, Caterina, Stefanini, Benedetta, Garajovà, Ingrid, Ielasi, Luca, De Lorenzo, Stefania, Granito, Alessandro, Stefanini, Bernardo, Masi, Gianluca, Lonardi, Sara, Brandi, Giovanni, Bruno, Daniele, Auriemma, Alessandra, Lani, Lorenzo, Campani, Claudia, Svegliati-Baroni, Gianluca, Piscaglia, Fabio

Source: In Journal of Hepatology June 2024 80 Supplement 1:S446-S446

SAT-477-YI The impact of etiologyon patterns of progression of advanced HCC

Authors: Stefanini, Bernardo, Piscaglia, Fabio, Dalbeni, Andrea, Vivaldi, Caterina, Federico, Piera, Palloni, Andrea, Soldà, Caterina, Stefanini, Benedetta, Garajova, Ingrid, Ielasi, Luca, De Lorenzo, Stefania, Masi, Gianluca, Lonardi, Sara, Brandi, Giovanni, Daniele, Bruno, Trevisani, Franco, Svegliati-Baroni, Gianluca, Campani, Claudia, Chen, Rusi, Tovoli, Francesco

Source: In Journal of Hepatology June 2024 80 Supplement 1:S395-S395

Asbestos exposure as an additional risk factor for small duct intrahepatic cholangiocarcinoma: a pilot study.

Authors: Vasuri, Francesco, Deserti, Marzia, Corradini, Angelo G., Tavolari, Simona, Relli, Valeria, Palloni, Andrea, Frega, Giorgio, Curti, Stefania, Mattioli, Stefano, Cescon, Matteo, D'Errico, Antonia, Brandi, Giovanni

Source: Scientific Reports; 2/13/2023, Vol. 13 Issue 1, p1-7, 7p

Subject Terms: ASBESTOS, CHOLANGIOCARCINOMA, TOXICOLOGY of asbestos, RISK exposure, PILOT projects, OCCUPATIONAL exposure, CASE-control method

Can repeated surgical resection offer a chance of cure for recurrent cholangiocarcinoma?

Authors: Laurenzi, Andrea, Brandi, Giovanni, Greco, Federica, Prosperi, Enrico, Palloni, Andrea, Serenari, Matteo, Frega, Giorgio, Ravaioli, Matteo, Rizzo, Alessandro, Cescon, Matteo

Source: Langenbeck's Archives of Surgery; Feb2023, Vol. 408 Issue 1, p1-6, 6p

Risk-adjusted analysis of survival variability among hospitals treating biliary malignancy.

Authors: Rimini, Margherita, Casadei-Gardini, Andrea, Brandi, Giovanni, Leone, Francesco, Fornaro, Lorenzo, Pella, Nicoletta, Silvestris, Nicola, Montagnani, Francesco, Lonardi, Sara, Lai, Eleonora, Galizia, Eva, Santini, Daniele, Palloni, Andrea, Filippi, Roberto, Masi, Gianluca, Aprile, Giuseppe, Aglietta, Massimo, Frega, Giorgio, Fenocchio, Elisabetta, Vivaldi, Caterina

Source: Journal of Chemotherapy (Taylor & Francis Ltd); Dec2022, Vol. 34 Issue 8, p543-549, 7p

Second-Line Chemotherapy in Elderly Patients with Advanced Biliary Tract Cancer: A Multicenter Real-World Study.

Authors: Rizzo, Alessandro, Salati, Massimiliano, Frega, Giorgio, Merz, Valeria, Caputo, Francesco, Di Federico, Alessandro, Palloni, Andrea, Carloni, Riccardo, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro, Messina, Carlo, Spallanzani, Andrea, Gelsomino, Fabio, Benatti, Stefania, Luppi, Gabriele, Melisi, Davide, Dominici, Massimo, Brandi, Giovanni

Source: Medicina (1010660X); Nov2022, Vol. 58 Issue 11, p1543, 9p

Subject Terms: BILIARY tract cancer, OLDER patients, LOG-rank test, PROGRESSION-free survival, SURVIVAL rate

Advances in novel systemic therapies for advanced hepatocellular carcinoma.

Authors: Carloni, Riccardo, Rizzo, Alessandro, Cusmai, Antonio, Palloni, Andrea, Federico, Alessandro Di, Marco, Mariacristina Di, Massafra, Raffaella, Fanizzi, Annarita, Palmiotti, Gennaro, Brandi, Giovanni

Source: Future Medicinal Chemistry; Oct2022, Vol. 14 Issue 20, p1455-1470, 16p