Glial cholesterol redistribution in hypoxic injury in vitro influences oligodendrocyte maturation and myelination

Authors: Shrivastava, Vadanya, Tyagi, Sagar, Dey, Devanjan, Singh, Archna, Palanichamy, Jayanth Kumar, Sinha, Subrata, Sharma, J.B., Seth, Pankaj, Sen, Sudip

Source: In BBA - Molecular Basis of Disease December 2024 1870(8)

Mosaic variegated aneuploidy syndrome 2 with biallelic novel CEP57 splice site variation in Indian siblings: Expanding the clinical and molecular spectrum

Authors: Langeh, Nitika, Saluja, Sumedha, Ethayathulla, Abdul Samath, Jana, Manisha, Shukla, Rashmi, Palanichamy, Jayanth Kumar, Gupta, Neerja

Source: Clinical genetics. 103(4):478-483

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176805165.0x000001&indx=1&recIds=ETOCvdc_100176805165.0x000001

Prognostic utility of key copy number alterations in T cell acute lymphoblastic leukemia

Authors: Kumari, Sarita, Ali, M. Shadab, Singh, Jay, Arora, Mohit, Verma, Deepak, Pandey, Avanish Kumar, Benjamin, Mercilena, Bakhshi, Sameer, Palanichamy, Jayanth Kumar, Sharma, Atul, Singh, Inder, Tanwar, Pranay, Singh, Amar Ranjan, Pushpam, Deepam, Qamar, Imteyaz, Chopra, Anita

Source: Hematological oncology. 40(4):577-587

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194610165.0x000001&indx=1&recIds=ETOCvdc_100194610165.0x000001

The RNA-binding protein IGF2BP3 is critical for MLL-AF4-mediated leukemogenesis

Authors: Tran, Tiffany M., Philipp, Julia, Bassi, Jaspal Singh, Nibber, Neha, Draper, Jolene M., Lin, Tasha L., Palanichamy, Jayanth Kumar, Jaiswal, Amit Kumar, Silva, Oscar, Paing, May, King, Jennifer, Katzman, Sol, Sanford, Jeremy R., Rao, Dinesh S.

Source: Leukemia. 36(1):68-79

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193142972.0x000001&indx=1&recIds=ETOCvdc_100193142972.0x000001

Loss of TET2 with reduced genomic 5-hmC is associated with adverse-risk AML

Authors: Pethusamy, Karthikeyan, Seethy, Ashikh, Dhar, Ruby, Karmakar, Abhibroto, Chaudhary, Shilpi, Bakhshi, Sameer, Palanichamy, Jayanth Kumar, Chopra, Anita, Chauhan, Shyam S., Karmakar, Subhradip

Source: Leukemia & lymphoma. 63(14):3426-3432

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173009799.0x000001&indx=1&recIds=ETOCvdc_100173009799.0x000001

Chronic hyperglycemia drives alterations in macrophage effector function in pulmonary tuberculosis

Authors: Panda, Sudhasini, Seelan, Diravya M, Faisal, Shah, Arora, Alisha, Luthra, Kalpana, Palanichamy, Jayanth Kumar, Mohan, Anant, Vikram, Naval K, Gupta, Neeraj Kumar, Ramakrishnan, Lakshmy, Singh, Archana

Source: European journal of immunology. 52(10):1595-1609

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168270025.0x000001&indx=1&recIds=ETOCvdc_100168270025.0x000001

Mitochondrial biogenesis gene POLG correlates with outcome in pediatric acute myeloid leukemia

Authors: Chaudhary, Shilpi, Ganguly, Shuvadeep, Singh, Archna, Palanichamy, Jayanth Kumar, Bakhshi, Radhika, Chopra, Anita, Bakhshi, Sameer

Source: Leukemia & lymphoma. 63(4):1005-1008

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159244957.0x000001&indx=1&recIds=ETOCvdc_100159244957.0x000001

BAALC gene expression tells a serious patient outcome tale in NPM1-wild type/FLT3-ITD negative cytogenetically normal-acute myeloid leukemia in adults

Authors: Verma, Deepak, Kumar, Rajive, Ali, M Shadab, Singh, Jay, Arora, Mohit, Singh, Inder, Kumari, Sarita, Bakhshi, Sameer, Sharma, Atul, Palanichamy, Jayanth Kumar, Tanwar, Pranay, Singh, Amar Ranjan, Chopra, Anita

Source: In Blood Cells, Molecules and Diseases July 2022 95

A patient with POLA1 splice variant expands the yet evolving phenotype of Van Esch O'Driscoll syndrome

Authors: Endrakanti, Mounika, Saluja, Sumedha, Ethayathulla, Abdul S., Sapra, Savita, Dalal, Ashwin, Palanichamy, Jayanth Kumar, Gupta, Neerja

Source: In European Journal of Medical Genetics August 2021 64(8)

Molecular associations and clinical significance of core NHEJ pathway genes in renal clear cell carcinoma

Authors: Singh, Jay, Arora, Mohit, Kumari, Sarita, Verma, Deepak, Palanichamy, Jayanth Kumar, Qamar, Imteyaz, Chauhan, Shyam S., Chopra, Anita

Source: In Gene Reports June 2021 23

PGC1A driven enhanced mitochondrial DNA copy number predicts outcome in pediatric acute myeloid leukemia

Authors: Chaudhary, Shilpi, Ganguly, Shuvadeep, Palanichamy, Jayanth Kumar, Singh, Archna, Bakhshi, Radhika, Jain, Ayushi, Chopra, Anita, Bakhshi, Sameer

Source: In Mitochondrion May 2021 58:246-254

Distinct oncogenic phenotypes in hematopoietic specific deletions of Trp53.

Authors: Palanichamy, Jayanth Kumar¹ (AUTHOR), Tran, Tiffany M.^2,3 (AUTHOR), King, Jennifer K.⁴ (AUTHOR), Katzman, Sol⁵ (AUTHOR), Ritter, Alexander J.⁶ (AUTHOR), Sharma, Gunjan¹ (AUTHOR), Tso, Christine² (AUTHOR), Contreras, Jorge R.² (AUTHOR), Fernando, Thilini R.² (AUTHOR), Sanford, Jeremy R.⁶ (AUTHOR), Rao, Dinesh S.^2,7,8,9 (AUTHOR) drao@mednet.ucla.edu

Source: Scientific Reports. 5/9/2023, Vol. 13 Issue 1, p1-14. 14p.

Subject Terms: *B cells, *DIFFUSE large B-cell lymphomas, *TUMOR suppressor genes, *MUCOSA-associated lymphoid tissue lymphoma, *HEMATOPOIETIC system, *PHENOTYPES

Using Human Fetal Neural Stem Cells to Elucidate the Role of the JAK-STAT Cell Signaling Pathway in Oligodendrocyte Differentiation In Vitro.

Authors: Dey, Devanjan, Tyagi, Sagar, Shrivastava, Vadanya, Rani, Sweety, Sharma, Jai Bhagwan, Sinha, Subrata, Palanichamy, Jayanth Kumar, Seth, Pankaj, Sen, Sudip

Source: Molecular Neurobiology; Aug2024, Vol. 61 Issue 8, p5738-5753, 16p

Refinement of Risk-Stratification of Cytogenetically Normal Acute Myeloid Leukemia Adult Patients by MN1 Expression.

Authors: Ningombam, Aparna, Verma, Deepak, Kumar, Rajive, Singh, Jay, Ali, M. Shadab, Pandey, Avanish Kumar, Singh, Inder, Bakhshi, Sameer, Sharma, Atul, Pushpam, Deepam, Palanichamy, Jayanth Kumar, Tanwar, Pranay, Singh, Amar Ranjan, Chopra, Anita

Source: Asian Pacific Journal of Cancer Prevention; Jul2024, Vol. 25 Issue 7, p2283-2289, 7p

ALL-352 Exploring DUX4-Rearranged B-ALL in India: Incidence, Molecular Pathways, and Potential Biomarkers

Authors: Benjamin, Mercilena, Singh, Jay, Pandey, Avanish Kumar, Thukral, Neha, Kumari, Sarita, Bakhshi, Sameer, Singh, Amitabh, Palanichamy, Jayanth Kumar, Singh, Inder Kumar, Seth, Rachna, Chopra, Anita

Source: Clinical lymphoma, myeloma & leukemia. 23(S1):S248-S249

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196316410.0x000001&indx=1&recIds=ETOCvdc_100196316410.0x000001

Anti-factor B antibodies in atypical hemolytic uremic syndrome.

Authors: Khandelwal, Priyanka, Nambiar, Shreesha, Saini, Rahul, Saini, Savita, Coshic, Poonam, Sinha, Aditi, Hari, Pankaj, Palanichamy, Jayanth Kumar, Bagga, Arvind

Source: Pediatric Nephrology; Jun2024, Vol. 39 Issue 6, p1909-1916, 8p

Subject Terms: AUTOANTIBODY analysis, IMMUNOGLOBULIN analysis, RISK assessment, RESEARCH funding, ENZYME-linked immunosorbent assay, HEMOGLOBINS, HEMOLYTIC-uremic syndrome, COMPLEMENT (Immunology), SEVERITY of illness index, DESCRIPTIVE statistics, GLOMERULONEPHRITIS, GENETIC variation, VOLUMETRIC analysis, BLOOD platelets, WESTERN immunoblotting, CONFIDENCE intervals, DISEASE relapse, GENETICS

Geographic Terms: INDIA

Inflammation as a driver of hematological malignancies.

Authors: Saluja, Sumedha, Bansal, Ishu, Bhardwaj, Ruchi, Beg, Mohammad Sabique, Palanichamy, Jayanth Kumar

Source: Frontiers in Oncology; 2024, p01-21, 21p

Subject Terms: HEMATOLOGIC malignancies, BONE marrow cells, MULTIPOTENT stem cells, TUMOR necrosis factors, HEMATOPOIETIC stem cells

HIF-2α mediates a marked increase in migration and stemness characteristics in a subset of glioma cells under hypoxia by activating an Oct-4/Sox-2-Mena (INV) axis

Authors: Bhagat, Mohita, Palanichamy, Jayanth Kumar, Ramalingam, Pradeep, Mudassir, Madeeha, Irshad, Khushboo, Chosdol, Kunzang, Sarkar, Chitra, Seth, Pankaj, Goswami, Sumanta, Sinha, Subrata, Chattopadhyay, Parthaprasad

Source: In International Journal of Biochemistry and Cell Biology May 2016 74:60-71

Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs.

Authors: Kaushik, Kriti, Kumar, Hemant, Mehta, Samriddhi, Palanichamy, Jayanth Kumar

Source: Molecular Biology Reports; 2/8/2024, Vol. 51 Issue 1, p1-9, 9p

POSTER: ALL-352 Exploring DUX4-Rearranged B-ALL in India: Incidence, Molecular Pathways, and Potential Biomarkers

Authors: Benjamin, Mercilena, Singh, Jay, Pandey, Avanish Kumar, Thukral, Neha, Kumari, Sarita, Bakhshi, Sameer, Singh, Amitabh, Palanichamy, Jayanth Kumar, Singh, Inder Kumar, Seth, Rachna, Chopra, Anita

Source: Clinical lymphoma, myeloma & leukemia. 23(S1):S151-S151

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196320335.0x000001&indx=1&recIds=ETOCvdc_100196320335.0x000001