Biomarkers associated with pulmonary exacerbations in a randomized trial of nintedanib for radiation pneumonitis

Authors: Moore, Zachary R., Huang, Xiaojing, Lobaugh, Stephanie, Zhang, Zhigang, Wong, Phillip, Geyer, Alexander, Pagano, Andrew, Rudin, Charles M., Jones, David R., Gomez, Daniel R., Deasy, Joseph O., Mak, Raymond, Schmitt, Adam M., Paik, Paul K., Rimner, Andreas

Source: In Radiotherapy and Oncology July 2024 196

Initial Chemotherapy for Locally Advanced and Metastatic NUT Carcinoma

Authors: Luo, Jia, Sanchez, Michelle, Lee, Elinton, Hertzler, Hans, Luong, Nhi, Mazzola, Emanuele, Finstein, Bryanna, Tamen, Rubii, Brisbane, Gifty, Nguyen, Tom, Paik, Paul K., Chaft, Jamie E., Cheng, Michael L., Khalil, Hassan, Piha-Paul, Sarina A., Sholl, Lynette M., Nishino, Mizuki, Jänne, Pasi A., DuBois, Steven G., Hanna, Glenn J., Shapiro, Geoffrey I., French, Christopher A.

Source: In Journal of Thoracic Oncology May 2024 19(5):829-838

Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung Cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation

Authors: Yang, Soo-Ryum, Gedvilaite, Erika, Ptashkin, Ryan, Chang, Jason, Ziegler, John, Mata, Douglas A., Villafania, Liliana B., Nafa, Khedoudja, Hechtman, Jaclyn F., Benayed, Ryma, Zehir, Ahmet, Benhamida, Jamal, Arcila, Maria E., Mandelker, Diana, Rudin, Charles M., Paik, Paul K., Drilon, Alexander, Schoenfeld, Adam J., Ladanyi, Marc

Source: In Journal of Thoracic Oncology March 2024 19(3):409-424

Health Utility Analysis of Tepotinib in Patients With Non-Small Cell Lung Cancer Harboring MET Exon 14 Skipping

Authors: Yang, Mo, Vioix, Helene, Hook, Emma S., Hatswell, Anthony J., Batteson, Rachael L., Gaumond, Bruce R., O'Brate, Aurora, Popat, Sanjay, Paik, Paul K.

Source: Value in health. 26(8):1155-1163

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194762937.0x000001&indx=1&recIds=ETOCvdc_100194762937.0x000001

Real-world outcomes in non-small-cell lung cancer patients with MET Exon 14 skipping mutation and brain metastases treated with capmatinib

Authors: Paik, Paul K, Goyal, Ravi K, Cai, Beilei, Price, Mark A, Davis, Keith L, Ansquer, Valerie Derrien, Caro, Nydia, Saliba, Teddy R

Source: Future oncology. 19(3):217-228

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189948700.0x000001&indx=1&recIds=ETOCvdc_100189948700.0x000001

Plain language summary of the development of tepotinib: a treatment for a subtype of non-small cell lung cancer called MET exon 14 skipping

Authors: Hallick, John, Baird, Anne-Marie, Falchook, Gerald, Le, Xiuning, Hong, David, Viteri, Santiago, Raskin, Jo, Reinmuth, Niels, Vlassak, Soetkin, Militaru, Mihaela, Paik, Paul K

Source: Future oncology. 19(10):683-696

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Cost-Effectiveness of Tepotinib Versus Capmatinib for the Treatment of Adult Patients With Metastatic Non–Small Cell Lung Cancer Harboring Mesenchymal–Epithelial Transition Exon 14 Skipping

Authors: Yang, Mo, Vioix, Helene, Sachdev, Rameet, Stargardter, Matthew, Tosh, Jon, Pfeiffer, Boris M., Paik, Paul K.

Source: Value in health. 26(4):487-497

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186854339.0x000001&indx=1&recIds=ETOCvdc_100186854339.0x000001

Survival Outcomes and Treatment Patterns in Patients With NFE2L2 and/or KEAP1 Mutation-Positive Advanced Squamous Cell NSCLC Using a Real-World Clinico-Genomic Database

Authors: Wu, Yanyu, Yin, Yu, Crossland, Victoria, Vincent, Sylvie, Paik, Paul K., Lineberry, Neil, Faller, Douglas V.

Source: In Clinical Lung Cancer September 2022 23(6):487-497

Safety of Tepotinib in Patients With MET Exon 14 Skipping NSCLC and Recommendations for Management

Authors: Veillon, Remi, Sakai, Hiroshi, Le, Xiuning, Felip, Enriqueta, Cortot, Alexis B., Smit, Egbert F., Park, Keunchil, Griesinger, Frank, Britschgi, Christian, Wu, Yi-Long, Melosky, Barbara, Baijal, Shobhit, Jr, Gilberto de Castro, Sedova, Michaela, Berghoff, Karin, Otto, Gordon, Paik, Paul K.

Source: In Clinical Lung Cancer June 2022 23(4):320-332

Safety of MET Tyrosine Kinase Inhibitors in Patients With MET Exon 14 Skipping Non-small Cell Lung Cancer: A Clinical Review

Authors: Cortot, Alexis, Le, Xiuning, Smit, Egbert, Viteri, Santiago, Kato, Terufumi, Sakai, Hiroshi, Park, Keunchil, Camidge, D. Ross, Berghoff, Karin, Vlassak, Soetkin, Paik, Paul K.

Source: In Clinical Lung Cancer May 2022 23(3):195-207

Real-world insights into patients with advanced NSCLC and MET alterations

Authors: Bittoni, Marisa, Yang, James Chih-Hsin, Shih, Jin-Yuan, Peled, Nir, Smit, Egbert F., Camidge, D. Ross, Arasada, Rajeswara Rao, Oksen, Dina, Boutmy, Emmanuelle, Stroh, Christopher, Johne, Andreas, Carbone, David P., Paik, Paul K.

Source: In Lung Cancer September 2021 159:96-106

A proteogenomic portrait of lung squamous cell carcinoma

Authors: Green, Alex, Molinolo, Alfredo, Francis, Alicia, Paulovich, Amanda G., Karnuta, Andrii, Colaprico, Antonio, Hindenach, Barbara, Pruetz, Barbara L., Kubisa, Bartosz, Druker, Brian J., Huynh, Carissa, Goldthwaite, Charles A., Jr., Birger, Chet, Kinsinger, Christopher R., Jones, Corbin D., Rohrer, Dan, Valley, Dana R., Chan, Daniel W., Chesla, David, Hansel, Donna, Ponomareva, Elena V., Duffy, Elizabeth, Burks, Eric, Schadt, Eric E., Fedorov, Eugene S., An, Eunkyung, Ding, Fei, Wilson, George D., Batra, Harsh, Zhang, Hui, Maas, Jennifer E., Eschbacher, Jennifer, Ketchum, Karen A., Rodland, Karin D., Hoadley, Katherine A., Suzuki, Kei, Um, Ki Sung, Qi, Liqun, Bernard, Lori, Wiznerowicz, Maciej, Wojtyś, Małgorzata, Domagalski, Marcin J., Ellis, Matthew J., Dyer, Maureen A., Borucki, Melissa, Anurag, Meenakshi, Birrer, Michael J., Xu, Midie, Krotevich, Mikhail, Roche, Nancy, Edwards, Nathan J., Vatanian, Negin, Mucci, Neil R., Maunganidze, Nicollette, Gabrovski, Nikolay, Potapova, Olga, Fadare, Oluwole, Grady, Pamela, McGarvey, Peter B., Hariharan, Pushpa, Thangudu, Ratna R., Montgomery, Rebecca, Pandurengan, Renganayaki, Smith, Richard D., Welsh, Robert J., Mareedu, Sailaja, Payne, Samuel H., Cottingham, Sandra, Singh, Shilpi, Tsang, Shirley X., Cai, Shuang, Gabriel, Stacey, Liu, Tao, Hiltke, Tara, Vashist, Tanmayi, Bauer, Thomas, Sovenko, Volodymyr, Tourtellotte, Warren G., Ma, Weiping, Bocik, William, Hasan, Wohaib, Jing, Xiaojun, Tang, Ximing, Liao, Yuxing, Yvonne, Shutack, Zhang, Zhen, Hanhan, Ziad, Satpathy, Shankha, Krug, Karsten, Jean Beltran, Pierre M., Savage, Sara R., Petralia, Francesca, Kumar-Sinha, Chandan, Dou, Yongchao, Reva, Boris, Kane, M. Harry, Avanessian, Shayan C., Vasaikar, Suhas V., Krek, Azra, Lei, Jonathan T., Jaehnig, Eric J., Omelchenko, Tatiana, Geffen, Yifat, Bergstrom, Erik J., Stathias, Vasileios, Christianson, Karen E., Heiman, David I., Cieslik, Marcin P., Cao, Song, Song, Xiaoyu, Ji, Jiayi, Liu, Wenke, Li, Kai, Wen, Bo, Li, Yize, Gümüş, Zeynep H., Selvan, Myvizhi Esai, Soundararajan, Rama, Visal, Tanvi H., Raso, Maria G., Parra, Edwin Roger, Babur, Özgün, Vats, Pankaj, Anand, Shankara, Schraink, Tobias, Cornwell, MacIntosh, Rodrigues, Fernanda Martins, Zhu, Houxiang, Mo, Chia-Kuei, Zhang, Yuping, da Veiga Leprevost, Felipe, Huang, Chen, Chinnaiyan, Arul M., Wyczalkowski, Matthew A., Omenn, Gilbert S., Newton, Chelsea J., Schurer, Stephan, Ruggles, Kelly V., Fenyö, David, Jewell, Scott D., Thiagarajan, Mathangi, Mesri, Mehdi, Rodriguez, Henry, Mani, Sendurai A., Udeshi, Namrata D., Getz, Gad, Suh, James, Li, Qing Kay, Hostetter, Galen, Paik, Paul K., Dhanasekaran, Saravana M., Govindan, Ramaswamy, Ding, Li, Robles, Ana I., Clauser, Karl R., Nesvizhskii, Alexey I., Wang, Pei, Carr, Steven A., Zhang, Bing, Mani, D.R., Gillette, Michael A.

Source: In Cell 5 August 2021 184(16):4348-4371

The Impact of Durvalumab on Local-Regional Control in Stage III NSCLCs Treated With Chemoradiation and on KEAP1-NFE2L2-Mutant Tumors

Authors: Shaverdian, Narek, Offin, Michael, Shepherd, Annemarie F., Simone, Charles B., II, Gelblum, Daphna Y., Wu, Abraham J., Hellmann, Matthew D., Rimner, Andreas, Paik, Paul K., Chaft, Jamie E., Gomez, Daniel R.

Source: In Journal of Thoracic Oncology August 2021 16(8):1392-1402

Genomic Analyses for Predictors of Response to Chemoradiation in Stage III Non-Small Cell Lung Cancer

Authors: Luo, Leo Y., Samstein, Robert M., Dick-Godfrey, Rosalind, Sidiqi, Baho, Wang, Chunyu, Oro, Federica, Sonnick, Mark, Paik, Paul K., Chaft, Jamie E., Shaverdian, Narek, Gomez, Daniel R., Rimner, Andreas, Wu, Abraham J.

Source: In Advances in Radiation Oncology January-February 2021 6(1)

Phase 1 Trial of MLN0128 (Sapanisertib) and CB-839 HCl (Telaglenastat) in Patients With Advanced NSCLC (NCI 10327): Rationale and Study Design

Authors: Riess, Jonathan W., Frankel, Paul, Shackelford, David, Dunphy, Mark, Badawi, Ramsey D., Nardo, Lorenzo, Cherry, Simon R., Lanza, Ian, Reid, Joel, Gonsalves, Wilson I., Kunos, Charles, Gandara, David R., Lara, Primo N., Newman, Edward, Paik, Paul K.

Source: Clinical lung cancer. 22(1):67-70

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134862199.0x000001&indx=1&recIds=ETOCvdc_100134862199.0x000001

Tepotinib in patients with NSCLC harbouring MET exon 14 skipping: Japanese subset analysis from the Phase II VISION study

Authors: Sakai, Hiroshi, Morise, Masahiro, Kato, Terufumi, Matsumoto, Shingo, Sakamoto, Tomohiro, Kumagai, Toru, Tokito, Takaaki, Atagi, Shinji, Kozuki, Toshiyuki, Tanaka, Hiroshi, Chikamori, Kenichi, Shinagawa, Naofumi, Takeoka, Hiroaki, Bruns, Rolf, Straub, Josef, Schumacher, Karl Maria, Paik, Paul K

Source: Japanese journal of clinical oncology. 51(8):1261-1268

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127210676.0x000001&indx=1&recIds=ETOCvdc_100127210676.0x000001

An open-label phase IB study to evaluate GSK3052230 in combination with paclitaxel and carboplatin, or docetaxel, in FGFR1-amplified non-small cell lung cancer

Authors: Morgensztern, Daniel, Karaseva, Nina, Felip, Enriqueta, Delgado, Ignacio, Burdaeva, Olga, Dómine, Manuel, Lara, Primo, Paik, Paul K., Lassen, Ulrik, Orlov, Sergey, Trigo, José, Shomova, Marina, Baker-Neblett, Katherine, Vasquez, James, Wang, Xiaowei, Yan, Li, Mitrica, Ionel, DeYoung, M. Phillip, Garrido, Pilar

Source: In Lung Cancer October 2019 136:74-79

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

Authors: Fan, Pang-Dian, Narzisi, Giuseppe, Jayaprakash, Anitha D., Venturini, Elisa, Robine, Nicolas, Smibert, Peter, Germer, Soren, Yu, Helena A., Jordan, Emmet J., Paik, Paul K., Janjigian, Yelena Y., Chaft, Jamie E., Wang, Lu, Jungbluth, Achim A., Middha, Sumit, Spraggon, Lee, Qiao, Huan, Lovly, Christine M., Kris, Mark G., Riely, Gregory J., Politi, Katerina, Varmus, Harold, Ladanyi, Marc

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun . 115(26), E6030-E6038.

Access URL: https://www.jstor.org/stable/26510853

Identifying the Optimal Radiation Dose in Locally Advanced Non–Small-cell Lung Cancer Treated With Definitive Radiotherapy Without Concurrent Chemotherapy

Authors: Sonnick, Mark A., Oro, Federica, Yan, Bernice, Desai, Anish, Wu, Abraham J., Shi, Weiji, Zhang, Zhigang, Gelblum, Daphna Y., Paik, Paul K., Yorke, Ellen D., Rosenzweig, Kenneth E., Chaft, Jamie E., Rimner, Andreas

Source: In Clinical Lung Cancer January 2018 19(1):e131-e140

A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers

Authors: Sabari, Joshua K, Offin, Michael, Stephens, Dennis, Ni, Andy, Lee, Adrian, Pavlakis, Nick, Clarke, Stephen, Diakos, Connie I, Datta, Sutirtha, Tandon, Nidhi, Martinez, Andres, Myers, Mackenzie L, Makhnin, Alex, Leger, Ysleni, Yu, Helena A, Paik, Paul K, Chaft, Jamie E, Kris, Mark G, Jeon, Jeong O, Borsu, Laetitia A, Ladanyi, Marc, Arcila, Maria E, Hernandez, Jennifer, Henderson, Samantha, Shaffer, Tristan, Garg, Kavita, DiPasquo, Dan, Raymond, Christopher K, Lim, Lee P, Li, Mark, Hellmann, Matthew D, Drilon, Alexander, Riely, Gregory J, Rusch, Valerie W, Jones, David R, Rimner, Andreas, Rudin, Charles M, Isbell, James M, Li, Bob T

Source: Journal of the National Cancer Institute. 111(6):575-583

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094730450.0x000001&indx=1&recIds=ETOCvdc_100094730450.0x000001