Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial

Authors: Gruell, Henning, Gunst, Jesper D, Cohen, Yehuda Z, Pahus, Marie H, Malin, Jakob J, Platten, Martin, Millard, Katrina G, Tolstrup, Martin, Jones, R Brad, Conce Alberto, Winnifer D, Lorenzi, Julio C C, Oliveira, Thiago Y, Kümmerle, Tim, Suárez, Isabelle, Unson-O'Brien, Cecilia, Nogueira, Lilian, Olesen, Rikke, Østergaard, Lars, Nielsen, Henrik, Lehmann, Clara, Nussenzweig, Michel C, Fätkenheuer, Gerd, Klein, Florian, Caskey, Marina, Søgaard, Ole S ^*

Source: In The Lancet Microbe March 2022 3(3):e203-e214

SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity

Authors: Nielsen, Stine SF, Vibholm, Line K, Monrad, Ida, Olesen, Rikke, Frattari, Giacomo S, Pahus, Marie H, Højen, Jesper F, Gunst, Jesper D, Erikstrup, Christian, Holleufer, Andreas, Hartmann, Rune, Østergaard, Lars, Søgaard, Ole S, Schleimann, Mariane H, Tolstrup, Martin

Source: In EBioMedicine June 2021 68

Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.

Authors: Gunst, Jesper D., Staerke, Nina B., Pahus, Marie H., Kristensen, Lena H., Bodilsen, Jacob, Lohse, Nicolai, Dalgaard, Lars S., Brønnum, Dorthe, Fröbert, Ole, Hønge, Bo, Johansen, Isik S., Monrad, Ida, Erikstrup, Christian, Rosendal, Regitze, Vilstrup, Emil, Mariager, Theis, Bove, Dorthe G., Offersen, Rasmus, Shakar, Shakil, Cajander, Sara, Jørgensen, Nis P., Sritharan, Sajitha S., Breining, Peter, Jespersen, Søren, Mortensen, Klaus L., Jensen, Mads L., Kolte, Lilian, Frattari, Giacomo S., Larsen, Carsten S., Storgaard, Merete, Nielsen, Lars P., Tolstrup, Martin, Sædder, Eva A., Østergaard, Lars J., Ngo, Hien T.T., Jensen, Morten H., Højen, Jesper F., Kjolby, Mads, Søgaard, Ole S.

Source: In EClinicalMedicine May 2021 35

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

Authors: Vibholm, Line K., Nielsen, Stine S.F., Pahus, Marie H., Frattari, Giacomo S., Olesen, Rikke, Andersen, Rebecca, Monrad, Ida, Andersen, Anna H.F., Thomsen, Michelle M., Konrad, Christina V., Andersen, Sidsel D., Højen, Jesper F., Gunst, Jesper D., Østergaard, Lars, Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin

Source: In EBioMedicine February 2021 64

Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8⁺ T cell immunity.

Authors: Rosás-Umbert, Miriam, Gunst, Jesper D., Pahus, Marie H., Olesen, Rikke, Schleimann, Mariane, Denton, Paul W., Ramos, Victor, Ward, Adam, Kinloch, Natalie N., Copertino, Dennis C., Escribà, Tuixent, Llano, Anuska, Brumme, Zabrina L., Brad Jones, R., Mothe, Beatriz, Brander, Christian, Fox, Julie, Nussenzweig, Michel C., Fidler, Sarah, Caskey, Marina

Source: Nature Communications; 10/29/2022, Vol. 13 Issue 1, p1-12, 12p

Subject Terms: CELLULAR immunity, IMMUNITY, IMMUNOGLOBULINS, INFECTION prevention, MONOCLONAL antibodies, HIV

THE IMPACT OF 3BNC117, 10-1074, AND LEFITOLIMOD ON HIV-1 PERSISTENCE: THE TITAN TRIAL.

Authors: Gunst, Jesper D., Reikvam, Dag Henrik, McMahon, James H., Pahus, Marie H., Højen, Jesper F., Johansen, Isik S., Nielsen, Henrik, Benfield, Thomas Lars, Gerstoft, Jan, Lewin, Sharon, Tolstrup, Martin, Rasmussen, Thomas A., Caskey, Marina, Nussenzweig, Michel C., Søgaard, Ole S.

Source: Topics in Antiviral Medicine; Apr2023, Vol. 31 Issue 2, p56-56, 1/3p

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