Biochemical characterisation of class III biotin protein ligases from Botrytis cinerea and Zymoseptoria tritici

Authors: Sternicki, Louise M., Nguyen, Stephanie, Pacholarz, Kamila J., Barran, Perdita, Pendini, Nicole R., Booker, Grant W., Huet, Yoann, Baltz, Rachel, Wegener, Kate L., Pukala, Tara L., Polyak, Steven W.

Source: In Archives of Biochemistry and Biophysics 30 September 2020 691

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

Authors: Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.

Source: In Journal of Biological Chemistry 29 May 2020 295(22):7595-7607

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

Authors: Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.

Source: Diabetologia. 63(2):313-323

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125282751.0x000001&indx=1&recIds=ETOCvdc_100125282751.0x000001

Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase

Authors: Pacholarz, Kamila J., Burnley, Rebecca J., Jowitt, Thomas A., Ordsmith, Victoria, Pisco, João Pedro, Porrini, Massimiliano, Larrouy-Maumus, Gérald, Garlish, Rachel A., Taylor, Richard J., de Carvalho, Luiz Pedro Sório, Barran, Perdita E.

Source: In Structure 2 May 2017 25(5):730-738

Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry

Authors: Pacholarz, Kamila J., Barran, Perdita E.

Source: In EuPA Open Proteomics June 2016 11:23-27

Distinguishing Loss of Structure from Subunit Dissociation for Protein Complexes with Variable Temperature Ion Mobility Mass Spectrometry

Authors: Pacholarz, Kamila J., Barran, Perdita E.

Source: Analytical chemistry. 87(12):6271-6279

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN601601927&indx=1&recIds=ETOCRN601601927

Insights into the Conformations of Three Structurally Diverse Proteins: Cytochrome c, p53, and MDM2, Provided by Variable-Temperature Ion Mobility Mass Spectrometry

Authors: Dickinson, Eleanor R., Jurneczko, Ewa, Pacholarz, Kamila J., Clarke, David J., Reeves, Matthew, Ball, Kathryn L., Hupp, Ted, Campopiano, Dominic, Nikolova, Penka V., Barran, Perdita E.

Source: Analytical chemistry. 87(6):3231-3238

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600100864&indx=1&recIds=ETOCRN600100864

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes.

Authors: Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.

Source: Diabetologia; Feb2020, Vol. 63 Issue 2, p313-323, 11p, 5 Graphs

MhuD from Mycobacterium tuberculosis: Probing a Dual Role in Heme Storage and Degradation.

Authors: Matthews, Sarah J., Pacholarz, Kamila J., France, Aidan P., Jowitt, Thomas A., Hay, Sam, Barran, Perdita E., Munro, Andrew W.

Source: ACS Infectious Diseases; 11/8/2019, Vol. 5 Issue 11, p1855-1866, 12p

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Hybrid mass spectrometry methods reveal lot-to-lot differences and delineate the effects of glycosylation on the tertiary structure of Herceptin®.

Authors: Upton, Rosie, Migas, Lukasz G., Pacholarz, Kamila J., Beniston, Richard G., Estdale, Sian, Firth, David, Barran, Perdita E.

Source: Chemical Science; 3/7/2019, Vol. 10 Issue 9, p2811-2820, 10p

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ChemInform Abstract: Mass Spectrometry Based Tools to Investigate Protein-Ligand Interactions for Drug Discovery.

Authors: Pacholarz, Kamila J.¹, Garlish, Rachel A.¹, Taylor, Richard J.¹, Barran, Perdita E.¹

Source: ChemInform. Aug2012, Vol. 43 Issue 35, pno-no. 1p.