Distribution and Neurochemical Characterization of Dorsal Root Ganglia (DRG) Neurons Containing Phoenixin (PNX) and Supplying the Porcine Urinary Bladder.

Authors: Janikiewicz, Paweł¹ (AUTHOR), Mazur, Urszula^1,2 (AUTHOR), Holak, Piotr^2,3 (AUTHOR), Karakina, Nastassia^1,3 (AUTHOR), Węglarz, Kamil^1,2 (AUTHOR), Majewski, Mariusz Krzysztof^1,3 (AUTHOR), Bossowska, Agnieszka¹ (AUTHOR) agnieszka.bossowska@uwm.edu.pl

Source: Cells (2073-4409). Apr2025, Vol. 14 Issue 7, p516. 24p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *DORSAL root ganglia, *CALCITONIN gene-related peptide, *NITRIC-oxide synthases, *BLADDER, *SENSORY neurons

Deconvolution Analysis of G and F-Actin Unfolding: Insights into the Thermal Stability and Structural Modifications Induced by PACAP.

Authors: Bukovics, Péter¹ (AUTHOR) peter.bukovics@aok.pte.hu, Lőrinczy, Dénes¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Apr2025, Vol. 26 Issue 7, p3336. 11p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *DIFFERENTIAL scanning calorimetry, *F-actin, *ACTIN, *DEPOLYMERIZATION

Abstracts from the 13th International Conference for Healthcare and Medical Students (ICHAMS).

Source: BMC Proceedings. 3/3/2025, Vol. 19 Issue 1, p1-27. 27p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *MEDICAL personnel, *MEDICAL students, *BRUTON tyrosine kinase, *SCIENTIFIC literature, *READABILITY (Literary style), CAUSE of death statistics

Effects of PACAP Deficiency on Immune Dysfunction and Peyer's Patch Integrity in Adult Mice.

Authors: Sparks, Jason¹ (AUTHOR) jason.sparks@aok.pte.hu, Meggyes, Matyas^2,3 (AUTHOR) lilla.makszin@aok.pte.hu, Makszin, Lilla^3,4 (AUTHOR), Jehn, Viktoria¹ (AUTHOR) jehn.viki00@gmail.com, Lugosi, Hedvig¹ (AUTHOR) hedviglugosi@gmail.com, Reglodi, Dora¹ (AUTHOR) dora.reglodi@aok.pte.hu, Szereday, Laszlo^2,3 (AUTHOR) szereday.laszlo@pte.hu

Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10676. 14p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *INFLAMMATORY bowel diseases, *PERFORINS, *CELL populations, *HEPATITIS A virus cellular receptors

Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling.

Authors: Castorina, Alessandro¹ (AUTHOR) alessandro.castorina@uts.edu.au, Scheller, Jurgen² (AUTHOR) jscheller@uni-duesseldorf.de, Keay, Kevin A.³ (AUTHOR) kevin.keay@sydney.edu.au, Marzagalli, Rubina¹ (AUTHOR), Rose-John, Stefan⁴ (AUTHOR) rosejohn@biochem.uni-kiel.de, Campbell, Iain L.⁵ (AUTHOR) iain.campbell@sydney.edu.au

Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9453. 16p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *VASOACTIVE intestinal peptide, *MESSENGER RNA, *CENTRAL nervous system, *INTERLEUKIN-6

Differential Expression of PACAP/VIP Receptors in the Post-Mortem CNS White Matter of Multiple Sclerosis Donors.

Authors: Jansen, Margo Iris¹ (AUTHOR) margo.jansen@student.uts.edu.au, Musumeci, Giuseppe² (AUTHOR) g.musumeci@unict.it, Castorina, Alessandro¹ (AUTHOR) alessandro.castorina@uts.edu.au

Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8850. 24p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *LEUKODYSTROPHY, *VASOACTIVE intestinal peptide, *DEMYELINATION, *CENTRAL nervous system

Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC1 receptor.

Authors: Tasma, Zoe¹ (AUTHOR), Rees, Tayla A.^1,2 (AUTHOR), Guo, Song^3,4 (AUTHOR), Tan, Sheryl⁵ (AUTHOR), O'Carroll, Simon J.⁵ (AUTHOR), Faull, Richard L. M.⁵ (AUTHOR), Curtis, Maurice A.⁵ (AUTHOR), Christensen, Sarah L.³ (AUTHOR), Hay, Debbie L.^2,6 (AUTHOR), Walker, Christopher S.^1,2 (AUTHOR) cs.walker@auckland.ac.nz

Source: British Journal of Pharmacology. Aug2024, Vol. 181 Issue 15, p2655-2675. 21p.

Subject Terms: *SPINAL cord, *PITUITARY adenylate cyclase activating polypeptide, *NOCICEPTIN, *G protein coupled receptors, *VASOACTIVE intestinal peptide, *PEPTIDES, *CELLULAR signal transduction

Exploring the Role of Neuropeptide PACAP in Cytoskeletal Function Using Spectroscopic Methods.

Authors: Vékony, Roland Gábor¹ (AUTHOR) rvkony35@gmail.com, Tamás, Andrea² (AUTHOR) andreatamassz@gmail.com, Lukács, András¹ (AUTHOR) andras.lukacs@aok.pte.hu, Ujfalusi, Zoltán¹ (AUTHOR) zoltan.ujfalusi@aok.pte.hu, Lőrinczy, Dénes¹ (AUTHOR) denes.lorinczy@aok.pte.hu, Takács-Kollár, Veronika¹ (AUTHOR) veronika.kollar@aok.pte.hu, Bukovics, Péter¹ (AUTHOR) peter.bukovics@aok.pte.hu

Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8063. 17p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *NEURONAL differentiation, *FLUORESCENCE quenching, *FLUORESCENCE spectroscopy, *PATHOLOGICAL physiology

Integrated Transcriptomic and Proteomic Study of the Mechanism of Action of the Novel Small-Molecule Positive Allosteric Modulator 1 in Targeting PAC1-R for the Treatment of D-Gal-Induced Aging Mice.

Authors: Liang, Lili¹ (AUTHOR), Chen, Shang¹ (AUTHOR), Su, Wanlin¹ (AUTHOR), Zhang, Huahua² (AUTHOR), Yu, Rongjie^1,3,4,5 (AUTHOR) tyrj@jnu.edu.cn

Source: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p3872. 23p.

Subject Terms: *LONGEVITY, *PITUITARY adenylate cyclase activating polypeptide, *PROTEOMICS, *DENTATE gyrus, *TRANSCRIPTOMES, *AGING

Investigation of PACAP38 and PAC1 Receptor Expression in Human Retinoblastoma and the Effect of PACAP38 Administration on Human Y-79 Retinoblastoma Cells.

Authors: Tóth, Dénes¹ (AUTHOR) denes.toth@aok.pte.hu, Fábián, Eszter² (AUTHOR) eszter.fabian@aok.pte.hu, Szabó, Edina² (AUTHOR) szaboedina90@gmail.com, Patkó, Evelin² (AUTHOR) evelin.patko@gmail.com, Vicena, Viktória² (AUTHOR) vicena.viktoria@gmail.com, Váczy, Alexandra² (AUTHOR) vaczyalexandra@gmail.com, Atlasz, Tamás^2,3 (AUTHOR) attam@gamma.ttk.pte.hu, Tornóczky, Tamás⁴ (AUTHOR) tornoczki.tamas@pte.hu, Reglődi, Dóra² (AUTHOR) dora.reglodi@aok.pte.hu

Source: Life (2075-1729). Feb2024, Vol. 14 Issue 2, p185. 14p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *RETINOBLASTOMA, *BREAST, *CELL survival, *CELL lines, *CLEARCUTTING

Understanding the Biological Relationship between Migraine and Depression.

Authors: Viudez-Martínez, Adrián¹ (AUTHOR) aviudezmartinez@gmail.com, Torregrosa, Abraham B.^2,3,4 (AUTHOR) a.bailen@umh.es, Navarrete, Francisco^2,3,4 (AUTHOR) fnavarrete@umh.es, García-Gutiérrez, María Salud^2,3,4 (AUTHOR) maria.ggutierrez@gmail.com

Source: Biomolecules (2218-273X). Feb2024, Vol. 14 Issue 2, p163. 37p.

Subject Terms: *NEUROPEPTIDES, *PITUITARY adenylate cyclase activating polypeptide, *MIGRAINE aura, *NEUROPEPTIDE Y, *MIGRAINE, *SUBSTANCE P

PACAP‐38 related modulation of the cranial parasympathetic projection: A novel mechanism and therapeutic target in severe primary headache.

Authors: Akerman, Simon¹ (AUTHOR) sakerman@umaryland.edu, Goadsby, Peter J.^2,3 (AUTHOR), Romero‐Reyes, Marcela¹ (AUTHOR)

Source: British Journal of Pharmacology. Feb2024, Vol. 181 Issue 3, p480-494. 15p.

Subject Terms: *PRIMARY headache disorders, *PITUITARY adenylate cyclase activating polypeptide, *SUMATRIPTAN, *NEUROPEPTIDES, *NEURAL transmission, *CLUSTER headache, *ADENYLATE cyclase, *EFFERENT pathways

The Role of Biomarkers Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Vasoactive Intestinal Peptide (VIP) in Chronic and Episodic Migraines: A Meta-Analysis.

Authors: Thapa, Sangharsha¹ (AUTHOR), Shah, Sangam² (AUTHOR), Bhattarai, Abhinav² (AUTHOR), Yadav, Rukesh² (AUTHOR), Yu, Fang¹ (AUTHOR), Chand, Swati³ (AUTHOR), Li, Jin¹ (AUTHOR)

Source: Acta Neurologica Scandinavica. 1/6/2024, p1-10. 10p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *VASOACTIVE intestinal peptide, *RANDOM effects model, *MIGRAINE, *BIOMARKERS

Impact Assessment of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Hemostatic Sponge on Vascular Anastomosis Regeneration in Rats.

Authors: Fazekas, Laszlo Adam¹ (AUTHOR) fazekas.laszlo@med.unideb.hu, Szabo, Balazs¹ (AUTHOR) balazs.szabo@med.unideb.hu, Szegeczki, Vince² (AUTHOR) szegeczki.vince@anat.med.unideb.hu, Filler, Csaba² (AUTHOR) filler.csaba@med.unideb.hu, Varga, Adam¹ (AUTHOR) varga.adam@med.unideb.hu, Godo, Zoltan Attila³ (AUTHOR) godo.zoltan@inf.unideb.hu, Toth, Gabor⁴ (AUTHOR) toth.gabor@med.u-szeged.hu, Reglodi, Dora⁵ (AUTHOR) dora.reglodi@aok.pte.hu, Juhasz, Tamas² (AUTHOR) juhaszt@anat.med.unideb.hu, Nemeth, Norbert¹ (AUTHOR) nemeth@med.unideb.hu

Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16695. 24p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *RATS, *ERYTHROCYTE deformability

Distribution and Chemistry of Phoenixin-14, a Newly Discovered Sensory Transmission Molecule in Porcine Afferent Neurons.

Authors: Mazur, Urszula¹ (AUTHOR) urszula.mazur@uwm.edu.pl, Lepiarczyk, Ewa¹ (AUTHOR) pawel.janikiewicz@uwm.edu.pl, Janikiewicz, Paweł¹ (AUTHOR) mariusz.majewski@uwm.edu.pl, Łopieńska-Biernat, Elżbieta² (AUTHOR) ela.lopienska@uwm.edu.pl, Majewski, Mariusz Krzysztof¹ (AUTHOR) agnieszka.bossowska@uwm.edu.pl, Bossowska, Agnieszka¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16647. 25p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *HYPOTHALAMUS, *CALCITONIN gene-related peptide, *NEURAL transmission, *DORSAL root ganglia, *NEURONS, *NITRIC-oxide synthases, *PEPTIDES

PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain.

Authors: Sbei, Sami¹ (AUTHOR), Moncrief, Taylor² (AUTHOR), Limjunyawong, Nathachit³ (AUTHOR), Zeng, Yaping² (AUTHOR), Green, Dustin P.² (AUTHOR) dugreen@UTMB.EDU

Source: Scientific Reports. 11/20/2023, Vol. 13 Issue 1, p1-9. 9p.

Subject Terms: *MAST cells, *PITUITARY adenylate cyclase activating polypeptide, *SUMATRIPTAN, *CONNECTIVE tissue cells, *SPREADING cortical depression, *NEUROPEPTIDES, *ADENYLATE cyclase, *PEPTIDES

From CGRP to PACAP, VIP, and Beyond: Unraveling the Next Chapters in Migraine Treatment.

Authors: Tanaka, Masaru¹ (AUTHOR) tanaka.masaru.1@med.u-szeged.hu, Szabó, Ágnes^2,3 (AUTHOR) szabo.agnes.4@med.u-szeged.hu, Körtési, Tamás^1,4,5 (AUTHOR) kortesi.tamas@szte.hu, Szok, Délia² (AUTHOR) szok.delia@med.u-szeged.hu, Tajti, János² (AUTHOR) tajti.janos@med.u-szeged.hu, Vécsei, László^1,2 (AUTHOR) vecsei.laszlo@med.u-szeged.hu

Source: Cells (2073-4409). Nov2023, Vol. 12 Issue 22, p2649. 21p.

Subject Terms: *SUMATRIPTAN, *PITUITARY adenylate cyclase activating polypeptide, *CALCITONIN gene-related peptide, *SPREADING cortical depression, *VASOACTIVE intestinal peptide, *PEPTIDES, *MIGRAINE

Potential Crosstalk between the PACAP/VIP Neuropeptide System and Endoplasmic Reticulum Stress—Relevance to Multiple Sclerosis Pathophysiology.

Authors: Withana, Minduli¹ (AUTHOR) umayaminduli.withana@student.uts.edu.au, Castorina, Alessandro¹ (AUTHOR) alessandro.castorina@uts.edu.au

Source: Cells (2073-4409). Nov2023, Vol. 12 Issue 22, p2633. 20p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *ENDOPLASMIC reticulum, *MULTIPLE sclerosis, *PATHOLOGICAL physiology, *VASOACTIVE intestinal peptide, *MYELIN oligodendrocyte glycoprotein, *NEUROPEPTIDES

Gene deletion of the PACAP/VIP receptor, VPAC2R, alters glycemic responses during metabolic and psychogenic stress in adult female mice.

Authors: Kozlova, Elena V.^1,2 (AUTHOR), Bishay, Anthony E.¹ (AUTHOR), Denys, Maximilian E.¹ (AUTHOR), Chinthirla, Bhuvaneswari D.¹ (AUTHOR), Valdez, Matthew C.^1,2 (AUTHOR), Spurgin, Kurt A.^1,2 (AUTHOR), Krum, Julia M.¹ (AUTHOR), Basappa, Karthik R.¹ (AUTHOR), Currás‐Collazo, Margarita C.¹ (AUTHOR) mcur@ucr.edu

Source: Journal of Neuroendocrinology. Nov2023, Vol. 35 Issue 11, p1-17. 17p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *VASOACTIVE intestinal peptide, *INSULIN shock, *PEPTIDES, *IMMOBILIZATION stress

Constitutive and conditional deletion reveals distinct phenotypes driven by developmental versus neurotransmitter actions of the neuropeptide PACAP.

Authors: Bakalar, Dana¹ (AUTHOR), Gavrilova, Oksana² (AUTHOR), Jiang, Sunny Z.¹ (AUTHOR), Zhang, Hai‐ying¹ (AUTHOR), Roy, Snehashis³ (AUTHOR), Williams, Sarah K.³ (AUTHOR), Liu, Naili² (AUTHOR), Wisser, Stephen³ (AUTHOR), Usdin, Ted B.³ (AUTHOR), Eiden, Lee E.¹ (AUTHOR) eidenl@mail.nih.gov

Source: Journal of Neuroendocrinology. Nov2023, Vol. 35 Issue 11, p1-20. 20p.

Subject Terms: *PITUITARY adenylate cyclase activating polypeptide, *NEURAL development, *KNOCKOUT mice, *CENTRAL nervous system, *PEPTIDES