Evidence That Peripheral Leptin Resistance in Omental Adipose Tissue and Liver Correlates with MASLD in Humans.

Authors: De la Cruz-Color, Lucia^1,2 (AUTHOR) lucia.delacruz@academicos.udg.mx, Dominguez-Rosales, Jose Alfredo² (AUTHOR), Maldonado-González, Montserrat³ (AUTHOR) montserratmaldonado@yahoo.com.mx, Ruíz-Madrigal, Bertha³ (AUTHOR) bertha.ruiz@academicos.udg.mx, Sánchez Muñoz, Martha P.⁴ (AUTHOR) cirugiapatriciasanchez@gmail.com, Zaragoza-Guerra, Vianney Alejandrina⁵ (AUTHOR) vazg@tec.mx, Espinoza-Padilla, Victor H.² (AUTHOR), Ruelas-Cinco, Elizabeth del C.⁶ (AUTHOR) elizabethruelas029@gmail.com, Ramírez-Meza, Sandra M.⁷ (AUTHOR) sandra.ramirez4084@academicos.udg.mx, Torres Baranda, José R.³ (AUTHOR) rodrigo.torresbaranda@gmail.com, González-Gutiérrez, María del R.⁵ (AUTHOR) dra.rocio.g@tec.mx, Hernandez Nazara, Zamira Helena² (AUTHOR) zamira.hernandez@academicos.udg.mx

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 12, p6420. 22p.

Subject Terms: *PHOSPHOLIPASES, *TRANSCRIPTION factors, *ADIPOSE tissues, *LEPTIN, *SUPPRESSORS of cytokine signaling, *LEPTIN receptors, *INSULIN sensitivity, *NON-alcoholic fatty liver disease

The Prevalence, Characteristics, and Putative Mechanisms of Dual Antigen-Positive Membranous Nephropathy: The Underestimated Condition.

Authors: Uchida, Takahiro¹ (AUTHOR) tu05090224@gmail.com, Oda, Takashi¹ (AUTHOR) takashio@tokyo-med.ac.jp

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5931. 11p.

Subject Terms: *PHOSPHOLIPASE A2, *PHOSPHOLIPASES, *KIDNEY diseases, *DISEASE complications, *ANTIGENS, *IMMUNE response

One-Step Affinity Purification of Leucine-Rich α 2 -Glycoproteins from Snake Sera and Characterization of Their Phospholipase A 2 -Inhibitory Activities as β-Type Phospholipase A 2 Inhibitors.

Authors: Shirai, Ryoichi^1,2 (AUTHOR) ryoichi_shirai@hosp.misasa.tottori.jp, Shibata, Kana¹ (AUTHOR) shinobu.fujii@ompu.ac.jp, Fujii, Shinobu¹ (AUTHOR) rikiro.fukunaga@ompu.ac.jp, Fukunaga, Rikiro¹ (AUTHOR), Inoue, Seiji^1,3 (AUTHOR) seiji.inoue@ompu.ac.jp

Source: Toxins. Mar2024, Vol. 16 Issue 3, p126. 12p.

Subject Terms: *SNAKE venom, *PHOSPHOLIPASES, *COBRAS, *SURFACE plasmon resonance, *SNAKES, *AMINO acid sequence, *CYTOCHROME c

Fungal pathogens and symbionts: Living off the fat of the land.

Authors: Nev, Olga A.¹, o.nev@exeter.ac.uk, David-Palma, Márcia², Heitman, Joseph², Brown, Alistair J. P.¹, Coelho, Marco A.²

Source: PLoS Pathogens; 9/26/2024, Vol. 20 Issue 9, p1-7, 7p

Cytosolic phospholipase A2 regulates lipid homeostasis under osmotic stress through PPARγ.

Authors: Parra, Leandro Gastón^1,2 (AUTHOR) lparra@docente.ffyb.uba.ar, Erjavec, Luciana Cecilia^1,2 (AUTHOR), Casali, Cecilia Irene^1,2 (AUTHOR) ccasali@ffyb.uba.ar, Zerpa Velazquez, Andrea¹ (AUTHOR), Weber, Karen¹ (AUTHOR), Setton‐Avruj, Clara Patricia^2,3 (AUTHOR) setton@qb.ffyb.uba.ar, Fernández Tome, María del Carmen^1,2 (AUTHOR) fertome@ffyb.uba.ar

Source: FEBS Journal. Feb2024, Vol. 291 Issue 4, p722-743. 22p.

Subject Terms: *PHOSPHOLIPASES, *ARACHIDONIC acid, *PHOSPHOLIPASE A2, *PEROXISOME proliferator-activated receptors, *HOMEOSTASIS, *CELL survival, *LIPID metabolism

Parvovirus B19 and Human Parvovirus 4 Encode Similar Proteins in a Reading Frame Overlapping the VP1 Capsid Gene.

Authors: Karlin, David G.^1,2 (AUTHOR) davidgkarlin@gmail.com

Source: Viruses (1999-4915). Feb2024, Vol. 16 Issue 2, p191. 18p.

Subject Terms: *PARVOVIRUS B19, *PHOSPHOLIPASES, *PHOSPHOLIPASE A2, *PROTEINS, *DNA viruses, *GENES

Mechanistic exploration of Yiqi Liangxue Shengji prescription on restenosis after balloon injury by integrating metabolomics with network pharmacology.

Authors: Mao, Tianshi¹ (AUTHOR), Xie, Long¹ (AUTHOR), Guo, Yanqiong² (AUTHOR), Ji, Xiang¹ (AUTHOR), Wan, Jie³ (AUTHOR), Cui, Xiaoyun³ (AUTHOR), Fan, Qian⁴ (AUTHOR), Liu, Wei⁴ (AUTHOR), Wang, Shuai⁴ (AUTHOR), Han, Wenbo⁴ (AUTHOR), Lin, Qian¹ (AUTHOR) linqian62@126.com, Jia, Wenhao⁴ (AUTHOR) jqhx@bucm.edu.cn

Source: Pharmaceutical Biology. Dec2023, Vol. 61 Issue 1, p1260-1273. 14p.

Subject Terms: *PHOSPHOLIPASES, *NITRIC-oxide synthases, *CHINESE medicine, *CAROTID intima-media thickness, *PERCUTANEOUS coronary intervention, *METABOLOMICS, *PHOSPHOLIPASE A2

The investigation of lipoprotein-related phospholipase A2 (LP-PLA2) V279F mutation in coronary artery disease.

Authors: Yaroglu, Hatice Yildirim¹ haticeyildirim@mersin.edu.tr, Akciger, Nazli², Sungur, Mehmet Ali³, Yilmaz, Dilek Cicek², Tamer, Lulufer⁴

Source: Annals of Medical of Research. Oct2023, Vol. 30 Issue 10, p1217-1222. 6p.

Subject Terms: *GENETIC risk score, *PHOSPHOLIPASES, *LIPOPROTEINS, *CORONARY artery disease, *PHOSPHOLIPASE A2, *GENOTYPES, *POLYMERASE chain reaction, *T cells

Verticillium longisporum phospholipase VlsPLA2 is a virulence factor that targets host nuclei and modulates plant immunity.

Authors: Rafiei, Vahideh¹ (AUTHOR), Vélëz, Heriberto¹ (AUTHOR), Piombo, Edoardo¹ (AUTHOR), Dubey, Mukesh¹ (AUTHOR), Tzelepis, Georgios¹ (AUTHOR) georgios.tzelepis@slu.se

Source: Molecular Plant Pathology. Sep2023, Vol. 24 Issue 9, p1078-1092. 15p.

Subject Terms: *DISEASE resistance of plants, *PHOSPHOLIPASES, *VERTICILLIUM, *LIPOLYTIC enzymes, *PHOSPHOLIPASE A2, *NUCLEAR membranes, *GENE expression

Phospholipase Family Enzymes in Lung Cancer: Looking for Novel Therapeutic Approaches.

Authors: Salucci, Sara¹ (AUTHOR) ilaria.versari2@studio.unibo.it, Aramini, Beatrice² (AUTHOR) beatrice.aramini2@unibo.it, Bartoletti-Stella, Anna² (AUTHOR) anna.bartoletti2@unibo.it, Versari, Ilaria¹ (AUTHOR), Martinelli, Giovanni³ (AUTHOR) giovanni.martinelli2@unibo.it, Blalock, William^4,5 (AUTHOR) blalockwl@yahoo.com, Stella, Franco² (AUTHOR) franco.stella@unibo.it, Faenza, Irene¹ (AUTHOR) sara.salucci@unibo.it

Source: Cancers. Jun2023, Vol. 15 Issue 12, p3245. 17p.

Subject Terms: *THERAPEUTIC use of enzymes, *PHOSPHOLIPASES, *LUNG tumors, *POLYESTERS, *GENE expression, *CELL cycle, *IMMUNOTHERAPY

Phospholipases in Gliomas: Current Knowledge and Future Perspectives from Bench to Bedside.

Authors: Marvi, Maria Vittoria¹ (AUTHOR) mariavittoria.marvi2@unibo.it, Neri, Irene¹ (AUTHOR) irene.neri3@unibo.it, Evangelisti, Camilla¹ (AUTHOR) camilla.evangelisti@unibo.it, Ramazzotti, Giulia¹ (AUTHOR) giulia.ramazzotti@unibo.it, Asioli, Sofia^2,3 (AUTHOR) niccolo.neri2@studio.unibo.it, Zoli, Matteo^2,3 (AUTHOR) matteo.zoli4@unibo.it, Mazzatenta, Diego^2,3 (AUTHOR) diego.mazzatenta@unibo.it, Neri, Niccolò³ (AUTHOR), Morandi, Luca^2,4 (AUTHOR) luca.morandi2@unibo.it, Tonon, Caterina^2,4 (AUTHOR) caterina.tonon@unibo.it, Lodi, Raffaele^2,4 (AUTHOR) raffaele.lodi@unibo.it, Franceschi, Enrico⁵ (AUTHOR) e.franceschi@isnb.it, McCubrey, James A.⁶ (AUTHOR) mccubreyj@ecu.edu, Suh, Pann-Ghill^7,8 (AUTHOR) pgsuh@kbri.re.kr, Manzoli, Lucia¹ (AUTHOR) lucia.manzoli@unibo.it, Ratti, Stefano¹ (AUTHOR) lucia.manzoli@unibo.it

Source: Biomolecules (2218-273X). May2023, Vol. 13 Issue 5, p798. 12p.

Subject Terms: *GLIOMAS, *PHOSPHOLIPASES, *BRAIN tumors, *BIOLOGICAL membranes, *LYSOPHOSPHOLIPIDS, *ARACHIDONIC acid

Systemic Loxoscelism, Less Frequent but More Deadly: The Involvement of Phospholipases D in the Pathophysiology of Envenomation.

Authors: Gremski, Luiza Helena¹ (AUTHOR), da Justa, Hanna Câmara¹ (AUTHOR), Polli, Nayanne Louise Costacurta¹ (AUTHOR), Schluga, Pedro Henrique de Caires¹ (AUTHOR), Theodoro, João Lucas¹ (AUTHOR), Wille, Ana Carolina Martins² (AUTHOR), Senff-Ribeiro, Andrea¹ (AUTHOR), Veiga, Silvio Sanches¹ (AUTHOR) veigass@ufpr.br

Source: Toxins. Jan2023, Vol. 15 Issue 1, p17. 16p.

Subject Terms: *ACUTE kidney failure, *PHOSPHOLIPASES, *LOXOSCELES, *VENOM, *PATHOLOGICAL physiology, *SYMPTOMS, *SPIDER venom, *SPHINGOMYELINASE

PNPLA3(I148M) Inhibits Lipolysis by Perilipin-5-Dependent Competition with ATGL.

Authors: Witzel, Hagen Roland¹ (AUTHOR), Schwittai, Inga Maria Gertrud¹ (AUTHOR), Hartmann, Nils¹ (AUTHOR), Mueller, Sebastian² (AUTHOR), Schattenberg, Jörn M.³ (AUTHOR), Gong, Xue-Min⁴ (AUTHOR), Backs, Johannes⁴ (AUTHOR), Schirmacher, Peter⁵ (AUTHOR), Schuppan, Detlef^6,7 (AUTHOR), Roth, Wilfried¹ (AUTHOR), Straub, Beate Katharina¹ (AUTHOR) beate.straub@uninmedizin-mainz.de

Source: Cells (2073-4409). Jan2023, Vol. 12 Issue 1, p73. 26p.

Subject Terms: *PHOSPHOLIPASES, *LIPOLYSIS, *NON-alcoholic fatty liver disease, *SINGLE nucleotide polymorphisms, *HUMAN cell culture, *PERILIPIN, *IMMUNOHISTOCHEMISTRY

Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ.

Authors: Hongming Li¹, Yumei Qiu¹, Mengdie Xie¹, Changsheng Ouyang², Xiaoyun Ding¹, Hao Zhang¹, Wei Dong³, Yinhua Xiong^1,4, Xilan Tang^1,4 tangxilan1983@163.com

Source: Korean Journal of Physiology & Pharmacology. Jan2023, Vol. 27 Issue 1, p75-84. 10p.

Subject Terms: *ATRIAL natriuretic peptides, *PHOSPHOLIPASES, *HYPERTROPHY, *MOMORDICA charantia, *METABOLIC regulation, *PROTEIN expression, *TRITERPENOIDS, *BRAIN natriuretic factor

The Role of Phospholipase Activity of Peroxiredoxin 6 in Its Transmembrane Transport and Protective Properties.

Authors: Sharapov, Mars G.¹ (AUTHOR) sharapov.mg@yandex.ru, Goncharov, Ruslan G.¹ (AUTHOR), Parfenyuk, Svetlana B.¹ (AUTHOR), Glushkova, Olga V.¹ (AUTHOR), Novoselov, Vladimir I.¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p15265. 17p.

Subject Terms: *PHOSPHOLIPASE A2, *PHOSPHOLIPASES, *IONIZING radiation, *METABOLIC detoxification, *CARRIER proteins, *MEMBRANE proteins, *PEROXIDASE

The Patatin–Like Phospholipase Domain Containing Protein 7 Regulates Macrophage Classical Activation through SIRT1/NF-κB and p38 MAPK Pathways.

Authors: Zhao, Zheng¹ (AUTHOR), Heier, Christoph² (AUTHOR), Pang, Huimin¹ (AUTHOR), Wang, Yu¹ (AUTHOR), Huang, Feifei¹ (AUTHOR), Chang, Pingan¹ (AUTHOR) changpa@cqupt.edu.cn

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p14983. 17p.

Subject Terms: *PROTEIN domains, *PHOSPHOLIPASES, *MACROPHAGE activation, *TUMOR necrosis factors, *NF-kappa B, *MACROPHAGES, *MITOGEN-activated protein kinases

Varying Modes of Selection Among Toxin Families in the Venoms of the Giant Desert Hairy Scorpions (Hadrurus).

Authors: Nystrom, Gunnar S.¹, Ellsworth, Schyler A.¹, Ward, Micaiah J.¹, Rokyta, Darin R.¹, drokyta@bio.fsu.edu

Source: Journal of Molecular Evolution; Dec2023, Vol. 91 Issue 6, p935-962, 28p

sPLA2 Wobbles on the Lipid Bilayer between Three Positions, Each Involved in the Hydrolysis Process.

Authors: Kuzmina, Natalia¹ (AUTHOR), Volynsky, Pavel² (AUTHOR), Boldyrev, Ivan² (AUTHOR), Alekseeva, Anna² (AUTHOR) anna@lipids.ibch.ru

Source: Toxins. Oct2022, Vol. 14 Issue 10, pN.PAG-N.PAG. 13p.

Subject Terms: *PHOSPHOLIPASES, *BEE venom, *MOLECULAR dynamics, *ATOMIC force microscopy, *LIPIDS, *HYDROLYSIS, *BILAYER lipid membranes, *BINDING sites

Expression of the C-Terminal Domain of Phospholipase Cβ3 Inhibits Signaling via Gαq-Coupled Receptors and Transient Receptor Potential Channels.

Authors: Thiel, Gerald¹ (AUTHOR) gerald.thiel@uks.eu, Rössler, Oliver G.¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Sep2022, Vol. 23 Issue 17, p9590. 16p.

Subject Terms: *TRP channels, *PHOSPHOLIPASES, *HELIX-loop-helix motifs, *PHOSPHOLIPASE C, *CELL membranes

Color stability and lipid oxidation in pork sausage as affected by rosemary extract and phospholipase A2: A possible role for depletion of neutral lipid hydroperoxides.

Authors: Whalin, James G.¹ (AUTHOR) whalin@wisc.edu, Liu, Ling¹ (AUTHOR), Rankin, Scott A.² (AUTHOR), Zhang, Wenjing¹ (AUTHOR), Richards, Mark P.¹ (AUTHOR)

Source: Journal of Food Processing & Preservation. Apr2022, Vol. 46 Issue 4, p1-12. 12p.

Subject Terms: Hydroperoxides, Phospholipases, Phospholipase A2, Free fatty acids, Pork, Sausages, Lipids