Altered B-cell, plasma cell, and antibody immune profiles in blood of patients with systemic mastocytosis

Authors: Pérez-Pons, Alba ^{a, b, c, d}, Henriques, Ana ^{d, e}, Contreras Sanfeliciano, Teresa ^f, Jara-Acevedo, María ^{a, b, c, d, g}, Navarro-Navarro, Paula ^{a, b, c, d, g}, García-Montero, Andrés C. ^{a, b, c, d}, Álvarez-Twose, Iván ^{c, d, e}, Lecrevisse, Quentin ^{a, b, c}, Fluxa, Rafael ^h, Sánchez-Muñoz, Laura ^{d, e}, Caldas, Carolina ^{a, b, d}, Pozo, Julio ^{a, b}, González-López, Óscar ^{a, b, d}, Pérez-Andrés, Martín ^{a, b, c}, Mayado, Andrea ^{a, b, c, d, ∗}, Orfao, Alberto ^{a, b, c, d, ∗, ∗}

Source: In The Journal of Allergy and Clinical Immunology February 2025 155(2):628-639

KITD816V mutation in blood for the diagnostic screening of systemic mastocytosis and mast cell activation syndromes

Authors: Navarro‐Navarro, Paula, Álvarez‐Twose, Iván, Pérez‐Pons, Alba, Henriques, Ana, Mayado, Andrea, García‐Montero, Andrés C., Sánchez‐Muñoz, Laura, González‐López, Oscar, Matito, Almudena, Caldas, Carolina, Jara‐Acevedo, María, Orfao, Alberto

Source: Allergy. 78(5):1347-1359

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181499422.0x000001&indx=1&recIds=ETOCvdc_100181499422.0x000001

Frequency and prognostic impact of blood-circulating tumor mast cells in mastocytosis

Authors: Henriques, Ana, Muñoz-González, Javier I., Sánchez-Muñoz, Laura, Matito, Almudena, Torres-Rivera, Lidia, Jara-Acevedo, María, Caldas, Carolina, Mayado, Andrea, Pérez-Pons, Alba, García-Montero, Andrés C., Álvarez-Twose, Iván, Orfao, Alberto

Source: Blood. 139(4):572-583

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183242175.0x000001&indx=1&recIds=ETOCvdc_100183242175.0x000001

Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers

Authors: Eiros, Rocío, Barreiro-Pérez, Manuel, Martín-García, Ana, Almeida, Julia, Villacorta, Eduardo, Pérez-Pons, Alba, Merchán, Soraya, Torres-Valle, Alba, Sánchez-Pablo, Clara, González-Calle, David, Pérez-Escurza, Oihane, Toranzo, Inés, Díaz-Peláez, Elena, Fuentes-Herrero, Blanca, Macías-Álvarez, Laura, Oliva-Ariza, Guillermo, Lecrevisse, Quentin, Fluxa, Rafael, Bravo-Grande, José L., Orfao, Alberto, Sánchez, Pedro L.

Source: Revista española de cardiología. 75(9):734-746

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170842787.0x000001&indx=1&recIds=ETOCvdc_100170842787.0x000001

Afección pericárdica y miocárdica tras infección por SARS-CoV-2: estudio descriptivo transversal en trabajadores sanitarios

Alternate Title: Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers (English)

Authors: Eiros, Rocío, Barreiro-Pérez, Manuel, Martín-García, Ana, Almeida, Julia, Villacorta, Eduardo, Pérez-Pons, Alba, Merchán, Soraya, Torres-Valle, Alba, Sánchez-Pablo, Clara, González-Calle, David, Pérez-Escurza, Oihane, Toranzo, Inés, Díaz-Peláez, Elena, Fuentes-Herrero, Blanca, Macías-Álvarez, Laura, Oliva-Ariza, Guillermo, Lecrevisse, Quentin, Fluxa, Rafael, Bravo-Grande, José L., Orfao, Alberto, Sánchez, Pedro L.

Source: In Revista Española de Cardiología September 2022 75(9):735-747

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study

Authors: Muñoz-González, Javier I, Álvarez-Twose, Iván, Jara-Acevedo, María, Zanotti, Roberta, Perkins, Cecelia, Jawhar, Mohamad, Sperr, Wolfgang R, Shoumariyeh, Khalid, Schwaab, Juliana, Greiner, Georg, Henriques, Ana, Caldas, Carolina, Fernández-Giménez, Carlos, Sánchez-Muñoz, Laura, Mayado, Andrea, Pérez-Pons, Alba, Schmitt-Graeff, Annette, Duyster, Justus, Tanasi, Ilaria, Olivieri, Francesco, Mora-Casterá, Elvira, Luna, Irene, Senent, Leonor, Bañas, Maria-Helena, Nuñez-García, Amanda, Jurado-Chacón, Manuel, Martín-Sánchez, Guillermo, Colado, Enrique, Xicoy, Blanca, Gener-Ricós, Georgina, Gotlib, Jason, Bonadonna, Patrizia, Reiter, Andreas, Valent, Peter, García-Montero, Andrés C, Orfao, Alberto ^*

Source: In The Lancet Haematology March 2021 8(3):e194-e204

T‐cell immune profile in blood of systemic mastocytosis: Association with disease features.

Authors: Pérez‐Pons, Alba^1,2,3,4 (AUTHOR), Teodosio, Cristina^1,2,3 (AUTHOR), Jara‐Acevedo, María^1,2,3,4,5 (AUTHOR), Henriques, Ana^4,6,7 (AUTHOR), Navarro‐Navarro, Paula^1,2,3,4,5 (AUTHOR), García‐Montero, Andrés C.^1,2,3,4 (AUTHOR), Álvarez‐Twose, Iván^2,4,6 (AUTHOR), Lecrevisse, Quentin^1,2,3 (AUTHOR), Fluxa, Rafael⁷ (AUTHOR), Sánchez‐Muñoz, Laura^2,4,6 (AUTHOR), Caldas, Carolina^1,2,3,4 (AUTHOR), Pozo, Julio^1,2,3 (AUTHOR), Martín, Silvia^1,2,3 (AUTHOR), Sanfeliciano, Teresa Contreras⁸ (AUTHOR), Pedreira, Carlos E.⁹ (AUTHOR), Botafogo, Vitor¹⁰ (AUTHOR), González‐López, Oscar^1,2 (AUTHOR), Mayado, Andrea^1,2,3,4 (AUTHOR), Orfao, Alberto^1,2,3,4 (AUTHOR) orfao@usal.es

Source: Allergy. Jul2024, Vol. 79 Issue 7, p1921-1937. 17p.

Subject Terms: *MAST cell disease, *LYMPHOCYTE subsets, *T cells, *KILLER cells, *B cells, *VENOM hypersensitivity

Altered innate immune profile in blood of systemic mastocytosis patients

Authors: Pérez‐Pons, Alba, Jara‐Acevedo, María, Henriques, Ana, Navarro‐Navarro, Paula, García‐Montero, Andrés C., Álvarez‐Twose, Iván, Pedreira, Carlos E., Sánchez‐Muñoz, Laura, Damasceno, Daniela, Caldas, Carolina, Muñoz‐González, Javier I., Matito, Almudena, Flores‐Montero, Juan, González‐López, Oscar, Criado, Ignacio, Mayado, Andrea, Orfao, Alberto

Source: Clinical and translational allergy. 12(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154712478.0x000001&indx=1&recIds=ETOCvdc_100154712478.0x000001

Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo.

Authors: Díez-Alonso, Laura, Falgas, Aïda, Arroyo-Ródenas, Javier, Romencín, Paola A., Martínez, Alba, Gómez-Rosel, Marina, Blanco, Belén, Jiménez-Reinoso, Anaïs, Mayado, Andrea, Pérez-Pons, Alba, Aguilar-Sopeña, Óscar, Ramírez-Fernández, Ángel, Segura-Tudela, Alejandro, Perez-Amill, Lorena, Tapia-Galisteo, Antonio, Domínguez-Alonso, Carmen, Rubio-Pérez, Laura, Jara, Maria, Solé, Francesc, Hangiu, Oana

Source: Science Translational Medicine; 2/14/2024, Vol. 16 Issue 734, p1-13, 13p

Subject Terms: MULTIPLE myeloma, T cells, IMMUNOLOGIC memory, BISPECIFIC antibodies, HEMATOLOGIC malignancies

High frequency of low-count monoclonal B-cell lymphocytosis in hospitalized COVID-19 patients

Authors: Oliva-Ariza, Guillermo ^∗, Fuentes-Herrero, Blanca ^∗, Carbonell, Cristina, Lecrevisse, Quentin, Pérez-Pons, Alba, Torres-Valle, Alba, Pozo, Julio, Martín-Oterino, José Ángel, González-López, Óscar, López-Bernús, Amparo, Bernal-Ribes, Marta, Belhassen-García, Moncef, Pérez-Escurza, Oihane, Pérez-Andrés, Martín, Vazquez, Lourdes, Hernández-Pérez, Guillermo, García Palomo, Francisco Javier, Leoz, Pilar, Costa-Alba, Pilar, Pérez-Losada, Elena, Yeguas, Ana, Santos Sánchez, Miryam, García-Blázquez, Marta, Morán-Plata, Francisco Javier, Damasceno, Daniela, Botafogo, Vitor, Muñoz-García, Noemí, Fluxa, Rafael, Contreras-Sanfeliciano, Teresa, Almeida, Julia, Marcos, Miguel, Orfao, Alberto ^∗

Source: In Blood 19 January 2023 141(3):309-314

Immune cell kinetics and antibody response in COVID‐19 patients with low‐count monoclonal B‐cell lymphocytosis.

Authors: Oliva‐Ariza, Guillermo, Fuentes‐Herrero, Blanca, Lecrevisse, Quentin, Carbonell, Cristina, Pérez‐Pons, Alba, Torres‐Valle, Alba, Pozo, Julio, Martín‐Oterino, José Ángel, González‐López, Óscar, López‐Bernús, Amparo, Bernal‐Ribes, Marta, Belhassen‐García, Moncef, Pérez‐Escurza, Oihane, Pérez‐Andrés, Martín, Vazquez, Lourdes, Hernández‐Pérez, Guillermo, García Palomo, Francisco Javier, Leoz, Pilar, Costa‐Alba, Pilar, Pérez‐Losada, Elena

Source: American Journal of Hematology; Dec2023, Vol. 98 Issue 12, p1909-1922, 14p

A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR-T cell therapy in B cell acute lymphoblastic leukemia

Authors: Falgàs, Aïda, Lázaro-Gorines, Rodrigo, Zanetti, Samanta Romina, Rubio-Pérez, Laura, Martínez, Alba, Vinyoles, Meritxell, Guerrero-Murillo, Mercedes, Fernández-Fuentes, Narcís, Roca-Ho, Heleia, Tirado, Néstor, Panisello, Carla, Velasco-Hernandez, Talia, Mayado, Andrea, Pérez-Pons, Alba, Genescà, Eulalia, Ribera, Josep-Maria, Ribera, Jordi, Camos, Mireia, Ramírez-Orellana, Manuel, Anguita, Eduardo, Ballerini, Paola, Fuster, José Luis, Juan, Manel, González-Navarro, Europa Azucena, Locatelli, Franco, Stam, Ronald W, Querol, Sergi, Velasco, Pablo, Ortiz-Maldonado, Valentín, Martínez-Cibrián, Nuria, Delgado, Julio, Orfao, Alberto, Álvarez-Vallina, Luis, Bueno, Clara, Menéndez, Pablo

Source: Blood; 20250101, Issue: Preprints

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Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma.

Authors: Damasceno, Daniela, Almeida, Julia, Teodosio, Cristina, Sanoja-Flores, Luzalba, Mayado, Andrea, Pérez-Pons, Alba, Puig, Noemi, Arana, Paula, Paiva, Bruno, Solano, Fernando, Romero, Alfonso, Matarraz, Sergio, van den Bossche, Wouter B. L., Flores-Montero, Juan, Durie, Brian, van Dongen, Jacques J. M., Orfao, Alberto, Hermouet, Sylvie

Source: Cancers; Mar2021, Vol. 13 Issue 6, p1454, 1p

Subject Terms: MULTIPLE myeloma diagnosis, HOMEOSTASIS, CYTOKINES, CELL physiology, MONOCLONAL gammopathies, CANCER patients, IMMUNE response, DESCRIPTIVE statistics, INFLAMMATORY mediators, MONOCYTES, IMMUNOCOMPETENT cells