Clinical classification and molecular interpretation of germline pathogenic TP53 variations detected by multigene panel testing in patients with possible cancer predisposition.

Authors: Onder, Gizem, Unal, Busra, Ozdemir, Ozkan, Amanvermez, Ufuk, Elmas, Merve Acıkel, Gokbayrak, Merve, Ugurtas, Cansu, Cine, Naci, Kalay, İrem, Ozbek, Ugur, Ng, Ozden Hatirnaz, Agaoglu, Nihat Bugra

Source: Molecular Genetics & Genomics; 4/24/2025, Vol. 300 Issue 1, p1-9, 9p

Managing CDH1 Cancer Risks in a Child: Complex Decision Making in a Family With Hereditary Diffuse Gastric Cancer.

Authors: Agaoglu, Nihat Bugra^1,2,3, Ng, Ozden Hatirnaz^4,5,6, Zemheri, Itir Ebru⁷, Unal, Busra², Gerenli, Nelgin⁸, Tosun, Ilkay⁷, Yazıcı, Hulya^9,10, Ozbek, Ugur^5,11, Kamihara, Junne^12,13,14, Rana, Huma Q.^1,14,15, HumaQ_rana@dfci.harvard.edu

Source: American Journal of Medical Genetics. Part A; Feb2025, Vol. 197 Issue 2, p1-5, 5p

Management of rare and undiagnosed diseases: insights from researchers and healthcare professionals in Türkiye.

Authors: Durmus, Sinem, Yucesan, Emrah, Aktug, Sinem, Utz, Begum, Caglayan, Ahmet Okay, Gencpinar, Pinar, Günay, Cagatay, Oktay, Yavuz, Yildirim, Ravza Nur, Yigit, Ayca, Ozbek, Ugur

Source: Frontiers in Public Health; 2025, p1-11, 11p

Prognostic gene alterations and clonal changes in childhood B-ALL

Authors: Erbilgin, Yucel, Firtina, Sinem, Mercan, Sevcan, Hatirnaz Ng, Ozden, Karaman, Serap, Tasar, Orcun, Karakas, Zeynep, Celkan, Tulin Tiraje, Zengin, Emine, Sarper, Nazan, Yildirmak, Zeynep Yildiz, Sisko, Sinem, Ozbek, Ugur, Sayitoglu, Muge

Source: In Leukemia Research August 2019 83

The Outcomes of Chronic Myeloid Leukemia Patients With Molecular Warning Responses During Imatinib Treatment According to the European LeukemiaNet 2013 Recommendations

Authors: Soysal, Teoman, Eskazan, Ahmet Emre, Serin, Istemi, Sadri, Sevil, Keskin, Dilek, Ozgur Yurttas, Nurgul, Berk, Selin, Erdogan Ozunal, Isil, Salihoglu, Ayse, Ar, Muhlis Cem, Ongoren, Seniz, Baslar, Zafer, Ozbek, Ugur, Aydin, Yildiz

Source: In Clinical Lymphoma, Myeloma and Leukemia July 2019 19(7):e377-e384

Molecular and In Silico Analysis of the CHEK2 Gene in Individuals with High Risk of Cancer Predisposition from Türkiye.

Authors: Ozdemir, Ozkan, Bychkovsky, Brittany L., Unal, Busra, Onder, Gizem, Amanvermez, Ufuk, Aydin, Eylul, Ergun, Berk, Sahin, Ilayda, Gokbayrak, Merve, Ugurtas, Cansu, Koroglu, Merve Nur, Cakir, Berfin, Kalay, Irem, Cine, Naci, Ozbek, Ugur, Rana, Huma Q., Hatirnaz Ng, Ozden, Agaoglu, Nihat Bugra

Source: Cancers; Nov2024, Vol. 16 Issue 22, p3876, 17p

Subject Terms: TUMOR risk factors, TUMOR genetics, RISK assessment, RESEARCH funding, GENETIC markers, TUMOR markers, DESCRIPTIVE statistics, TUMOR suppressor genes, GENETIC mutation

Geographic Terms: TURKEY

Gene expression analysis reveals a strong signature of an interferon induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer

Authors: Einav, Uri, Tabach, Yuval, Getz, Gad, Yitzhaky, Assif, Ozbek, Ugur, Amariglio, Ninette, Izraeli, Shai, Rechavi, Gideon, Domany, Eytan

Source: Oncogene vol 24 p 6367 (2005)

Subject Terms: Quantitative Biology - Genomics, Quantitative Biology - Molecular Networks

Access URL: http://arxiv.org/abs/q-bio/0511017

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study

Authors: May, Patrick, Girard, Simon, Harrer, Merle, Bobbili, Dheeraj R, Schubert, Julian, Wolking, Stefan, Becker, Felicitas, Lachance-Touchette, Pamela, Meloche, Caroline, Gravel, Micheline, Niturad, Cristina E, Knaus, Julia, De Kovel, Carolien, Toliat, Mohamad, Polvi, Anne, Iacomino, Michele, Guerrero-López, Rosa, Baulac, Stéphanie, Marini, Carla, Thiele, Holger, Altmüller, Janine, Jabbari, Kamel, Ruppert, Ann-Kathrin, Jurkowski, Wiktor, Lal, Dennis, Rusconi, Raffaella, Cestèle, Sandrine, Terragni, Benedetta, Coombs, Ian D, Reid, Christopher A, Striano, Pasquale, Caglayan, Hande, Siren, Auli, Everett, Kate, Møller, Rikke S, Hjalgrim, Helle, Muhle, Hiltrud, Helbig, Ingo, Kunz, Wolfram S, Weber, Yvonne G, Weckhuysen, Sarah, De Jonghe, Peter, Sisodiya, Sanjay M, Nabbout, Rima, Franceschetti, Silvana, Coppola, Antonietta, Vari, Maria S, Kasteleijn-Nolst Trenité, Dorothée, Baykan, Betul, Ozbek, Ugur, Bebek, Nerses, Klein, Karl M, Rosenow, Felix, Nguyen, Dang K, Dubeau, François, Carmant, Lionel, Lortie, Anne, Desbiens, Richard, Clément, Jean-François, Cieuta-Walti, Cécile, Sills, Graeme J, Auce, Pauls, Francis, Ben, Johnson, Michael R, Marson, Anthony G, Berghuis, Bianca, Sander, Josemir W, Avbersek, Andreja, McCormack, Mark, Cavalleri, Gianpiero L, Delanty, Norman, Depondt, Chantal, Krenn, Martin, Zimprich, Fritz, Peter, Sarah, Nikanorova, Marina, Kraaij, Robert, van Rooij, Jeroen, Balling, Rudi, Arfan Ikram, M, Uitterlinden, André G, Avanzini, Giuliano, Schorge, Stephanie, Petrou, Steven, Mantegazza, Massimo, Sander, Thomas, LeGuern, Eric, Serratosa, Jose M, Koeleman, Bobby P C, Palotie, Aarno, Lehesjoki, Anna-Elina, Nothnagel, Michael, Nürnberg, Peter, Maljevic, Snezana, Zara, Federico, Cossette, Patrick, Krause, Roland, Lerche, Holger, Ferlazzo, Edoardo, di Bonaventura, Carlo, La Neve, Angela, Tinuper, Paolo, Bisulli, Francesca, Vignoli, Aglaia, Capovilla, Giuseppe, Crichiutti, Giovanni, Gambardella, Antonio, Belcastro, Vincenzo, Bianchi, Amedeo, Yalçın, Destina, Dizdarer, Gulsen, Arslan, Kezban, Yapıcı, Zuhal, Kuşcu, Demet, Leu, Costin, Heggeli, Kristin, Willis, Joseph, Langley, Sarah R, Jorgensen, Andrea, Srivastava, Prashant, Rau, Sarah, Hengsbach, Christian, Sonsma, Anja C.M., Jonghe, Peter De, Ikram, M Arfan

Source: In The Lancet Neurology August 2018 17(8):699-708

UZEP: A CLOUD-BASED DISTANCE EDUCATION PLATFORM FOR HIGHER EDUCATION INSTITUTIONS.

Authors: KAYNAK, Baran¹, kaynak@sakarya.edu.tr, TUNA, Osman², osmantuna@sakarya.edu.tr, OZBEK, Ugur³, uozbek@sakarya.edu.tr, AKSOY, Ali³, aliaksoy@sakarya.edu.tr, OZMEN, Ahmet¹, ozmen@sakarya.edu.tr, HORZUM, M. Baris⁴, mhorzum@sakarya.edu.tr, GOL, Burak³, bgol@sakarya.edu.tr

Source: Turkish Online Journal of Distance Education (TOJDE); Oct2023, Vol. 24 Issue 4, p220-237, 18p

Outcomes of Chronic Myeloid Leukemia Patients With Early Molecular Response at 3 and 6 Months: A Comparative Analysis of Generic Imatinib and Glivec

Authors: Eskazan, Ahmet Emre, Sadri, Sevil, Keskin, Dilek, Ayer, Mesut, Kantarcioglu, Bulent, Demirel, Naciye, Aydin, Demet, Aydinli, Fuat, Yokus, Osman, Ozunal, Isil Erdogan, Berk, Selin, Yalniz, Fevzi Firat, Elverdi, Tugrul, Salihoglu, Ayse, Ar, Muhlis Cem, Ongoren, Seniz, Baslar, Zafer, Aydin, Yildiz, Tuzuner, Nukhet, Ozbek, Ugur, Soysal, Teoman

Source: In Clinical Lymphoma Myeloma and Leukemia December 2017 17(12):804-811

Betulin Stimulates Osteogenic Differentiation of Human Osteoblasts-Loaded Alginate–Gelatin Microbeads.

Authors: Karaca, Mehmet Ali, Kancagi, Derya Dilek, Ozbek, Ugur, Ovali, Ercument, Gok, Ozgul

Source: Bioengineering (Basel); Jun2024, Vol. 11 Issue 6, p553, 16p

Subject Terms: BETULIN, MICROBEADS, TERIPARATIDE, BONE remodeling, BONE regeneration, STEM cell treatment

Clinical and genetic features of PKAN patients in a tertiary centre in Turkey

Authors: Akcakaya, Nihan Hande, Iseri, Sibel Ugur, Bilir, Birdal, Battaloglu, Esra, Tekturk, Pinar, Gultekin, Murat, Akar, Gokcen, Yigiter, Remzi, Hanagasi, Hasmet, Alp, Recep, Cagirici, Sultan, Eraksoy, Mefkure, Ozbek, Ugur, Yapici, Zuhal

Source: In Clinical Neurology and Neurosurgery March 2017 154:34-42

Two rare autosomal recessive neurological disorders identified by combined genetic approaches in a single consanguineous family with multiple offspring.

Authors: Susgun, Seda, Yucesan, Emrah, Goncu, Beyza, Hasanoglu Sayin, Sevde, Kina, Umit Yasar, Ozgul, Cemil, Duzenli, Omer Faruk, Kocaturk, Ozcan, Calik, Mustafa, Ozbek, Ugur, Ugur Iseri, Sibel Aylin

Source: Neurological Sciences; May2024, Vol. 45 Issue 5, p2271-2277, 7p

Subject Terms: NEUROLOGICAL disorders, AUTISM spectrum disorders, GENE expression, EPILEPSY, GENETIC counseling, SYMPTOMS

Clinical management of three JMML siblings with germline CBL variation

Authors: Agaoglu, Nihat Bugra ^{a, b, 1}, Yalcın, Koray ^{c, d, 1}, Unal, Busra ^a, Onder, Gizem ^{e, f}, Celen, Safiye Suna ^c, Zhumatayev, Suleimen ^c, Ozbek, Ugur ^g, Ng, Ozden Hatirnaz ^{f, h, ⁎}

Source: In Cancer Genetics April 2025 292-293:120-123

Chronic myeloid leukemia patients who develop grade I/II pleural effusion under second-line dasatinib have better responses and outcomes than patients without pleural effusion

Authors: Eskazan, Ahmet Emre, Eyice, Deniz, Kurt, Enes Ali, Elverdi, Tugrul, Yalniz, Fevzi Firat, Salihoglu, Ayse, Ar, Muhlis Cem, Ongoren Aydin, Seniz, Baslar, Zafer, Ferhanoglu, Burhan, Aydin, Yildiz, Tuzuner, Nukhet, Ozbek, Ugur, Soysal, Teoman

Source: In Leukemia Research July 2014 38(7):781-787

A new line method; A direct test in spinal muscular atrophy screening for DBS.

Authors: Kubar, Ayhan, Temel, Sehime Gülsüm, Beken, Serdar, Onder, Gizem, Hatirnaz, Ozden, Korkmaz, Ayse, Alanay, Yasemin, Ozbek, Ugur, Sag, Sebnem Ozemri, Ergoren, Mahmut Cerkez, Kubar, Elif, Sonmezalp, Candan Zeynep, Doğan, Ozlem

Source: Molecular Genetics & Genomic Medicine; Dec2023, Vol. 11 Issue 12, p1-8, 8p

Subject Terms: SPINAL muscular atrophy, MEDICAL screening, DRIED blood spot testing, NEWBORN screening, DIAGNOSTIC use of polymerase chain reaction, DEEP brain stimulation, DNA fingerprinting

Mediastinal adipose tissue expresses a pathogenic profile of 11 β-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease

Authors: Atalar, Fatmahan, Gormez, Selcuk, Caynak, Baris, Akan, Gokce, Tanriverdi, Gamze, Bilgic-Gazioglu, Sema, Gunay, Demet, Duran, Cihan, Akpinar, Belhhan, Ozbek, Ugur, Buyukdevrim, Ahmet Sevim, Yazıcı, Zeliha

Source: In Cardiovascular Pathology May-June 2013 22(3):183-188

Evaluation of PAX5 gene in the early stages of leukemic B cells in the childhood B cell acute lymphoblastic leukemia

Authors: Firtina, Sinem, Sayitoglu, Muge, Hatirnaz, Ozden, Erbilgin, Yucel, Oztunc, Ceren, Cinar, Suzan, Yildiz, Inci, Celkan, Tiraje, Anak, Sema, Unuvar, Aysegul, Devecioglu, Omer, Timur, Cetin, Aydogan, Gonul, Akcay, Arzu, Atay, Didem, Turkkan, Emine, Karaman, Serap, Orhaner, Betul, Sarper, Nazan, Deniz, Gunnur, Ozbek, Ugur

Source: In Leukemia Research 2012 36(1):87-92

Preparation of Cell-Loaded Microbeads as Stable and Injectable Delivery Platforms for Tissue Engineering.

Authors: Karaca, Mehmet Ali, Kancagi, Derya Dilek, Ozbek, Ugur, Ovali, Ercument, Gok, Ozgul

Source: Biomimetics (2313-7673); Jun2023, Vol. 8 Issue 2, p155, 17p

Subject Terms: MICROBEADS, CELLULAR therapy, MESENCHYMAL stem cells, CELL transplantation, TISSUE engineering

Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: a European LeukemiaNet Study

Authors: Baccarani, Michele, Rosti, Gianantonio, Castagnetti, Fausto, Haznedaroglu, Ibrahim, Porkka, Kimmo, Abruzzese, Elisabetta, Alimena, Giuliana, Ehrencrona, Hans, Hjorth-Hansen, Henrik, Kairisto, Veli, Levato, Luciano, Martinelli, Giovanni, Nagler, Arnon, Lanng Nielsen, Johan, Ozbek, Ugur, Palandri, Francesca, Palmieri, Fausto, Pane, Fabrizio, Rege-Cambrin, Giovanna, Russo, Domenico, Specchia, Giorgina, Testoni, Nicoletta, Weiss-Bjerrum, Ole, Saglio, Giuseppe, Simonsson, Bengt

Source: In Blood 7 May 2009 113(19):4497-4504