Évolution du statut braf dans le melanome : mythe ou Réalité ?

Alternate Title: BRAF mutation evolution in melanoma: Myth or reality? (English)

Authors: Molines, Elicia, Haffner, Aurélie, Fina, Frédéric, Malissen, Nausicaa, Ouafik, L’Houcine, Grob, Jean-Jacques, Macagno, Nicolas

Source: In Annales de Pathologie March 2022 42(2):113-118

Molecular characterization of fast-growing melanomas

Authors: Gaudy-Marqueste, Caroline, Macagno, Nicolas, Loundou, Anderson, Pellegrino, Eric, Ouafik, L'houcine, Budden, Timothy, Mundra, Piyushkumar, Gremel, Gabriela, Akhras, Victoria, Lin, Lijing, Cook, Martin, Kumar, Rajiv, Grob, Jean-Jacques, Nagore, Eduardo, Marais, Richard, Virós, Amaya

Source: In Journal of the American Academy of Dermatology February 2022 86(2):312-321

Cytoprotective effect of ethyl acetate fraction from Ephedra fragilis on H2O2-induced oxidative damage in Tetrahymena pyriformis

Authors: Guenaou, Ismail, Hmimid, Fouzia, Lahlou, Fatima Azzahra, Errami, Ahmed, Irahal, Imane Nait, Fahde, Sirine, Ouafik, ’L'houcine, Bourhim, Noureddine

Source: In Comparative Biochemistry and Physiology, Part C January 2021 239

Identification of the chemical composition of six essential oils with mass spectroscopy and evaluation of their antibacterial and antioxidant potential

Authors: Nait Irahal, Imane, azzahra Lahlou, Fatima, Hmimid, Fouzia, Errami, Ahmed, Guenaou, Ismail, Diawara, Idrissa, Kettani‐Halabi, Mohamed, Fahde, Sirine, Ouafik, L'Houcine, Bourhim, Noureddine

Source: Flavour and fragrance journal. 36(4):465-476

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122644767.0x000001&indx=1&recIds=ETOCvdc_100122644767.0x000001

Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes

Authors: Ruppert, Anne-Marie, Beau-Faller, Michèle, Debieuvre, Didier, Ouafik, L’Houcine, Westeel, Virginie, Rouquette, Isabelle, Mazières, Julien, Bringuier, Pierre-Paul, Monnet, Isabelle, Escande, Fabienne, Ricordel, Charles, Merlio, Jean-Philippe, Janicot, Henri, Lemoine, Antoinette, Foucher, Pascal, Poudenx, Michel, Morin, Franck, Langlais, Alexandra, Souquet, Pierre-Jean, Barlesi, Fabrice, Wislez, Marie

Source: In JTO Clinical and Research Reports September 2020 1(3)

Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project

Authors: Beau-Faller, Michèle ^*, Pencreach, Erwan, Leduc, Charlotte, Blons, Hélène, Merlio, Jean-Philippe, Bringuier, Pierre-Paul, de Fraipont, Florence, Escande, Fabienne, Lemoine, Antoinette, Ouafik, L'Houcine, Denis, Marc, Hofman, Paul, Lacave, Roger, Melaabi, Samia, Langlais, Alexandra, Missy, Pascale, Morin, Franck, Moro-Sibilot, Denis, Barlesi, Fabrice, Cadranel, Jacques

Source: In Lung Cancer February 2020 140:19-26

Simultaneous determination of cytosine arabinoside and its metabolite uracil arabinoside in human plasma by LC-MS/MS: Application to pharmacokinetics-pharmacogenetics pilot study in AML patients

Authors: Donnette, Melanie, Solas, Caroline, Giocanti, Madeleine, Venton, Geoffroy, Farnault, Laure, Berda-Haddad, Yael, Hau, Le Thi Thu, Costello, Régis, Ouafik, L'Houcine, Lacarelle, Bruno, Ciccolini, Joseph, Fanciullino, Raphaëlle

Source: In Journal of Chromatography B 15 September 2019 1126-1127

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

Authors: Civenni, Gianluca, Bosotti, Roberto, Timpanaro, Andrea, Vàzquez, Ramiro, Merulla, Jessica, Pandit, Shusil, Rossi, Simona, Albino, Domenico, Allegrini, Sara, Mitra, Abhishek, Mapelli, Sarah N., Vierling, Luca, Giurdanella, Martina, Marchetti, Martina, Paganoni, Alyssa, Rinaldi, Andrea, Losa, Marco, Mira-Catò, Enrica, D'Antuono, Rocco, Morone, Diego, Rezai, Keyvan, D'Ambrosio, Gioacchino, Ouafik, L’Houcine, Mackenzie, Sarah, Riveiro, Maria E., Cvitkovic, Esteban, Carbone, Giuseppina M., Catapano, Carlo V.

Source: In Cell Metabolism 6 August 2019 30(2):303-318

Clinical outcomes of non–small-cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France study

Authors: Couraud, Sébastien, Barlesi, Fabrice, Fontaine-Deraluelle, Clara, Debieuvre, Didier, Merlio, Jean-Philippe, Moreau, Lionel, Beau-Faller, Michèle, Veillon, Rémi, Mosser, Jean, Al Freijat, Faraj, Bringuier, Pierre-Paul, Léna, Hervé, Ouafik, L'Houcine, Westeel, Virginie, Morel, Alain, Audigier-Valette, Clarisse, Missy, Pascale, Langlais, Alexandra, Morin, Franck, Souquet, Pierre-Jean, Planchard, David

Source: In European Journal of Cancer July 2019 116:86-97

Molecularly matched targeted therapy: a promising approach for refractory metastatic melanoma.

Authors: Connell, Emily, Gerard, Émilie, Oules, Bénédicte, Brunet-Possenti, Florence, Lamoureux, Anouck, Bonnefille, Hugo, Mary-Prey, Sorilla, Carrasquilla, Ana, Mouret, Stéphane, Kramkimel, Nora, Lesage, Candice, Stoebner, Pierre-Emmanuel, Bartoli, Axel, Monestier, Sandrine, Correard, Florian, Gros, Audrey, Jeanson, Arnaud, Ouafik, L'Houcine, Gaudy-Marqueste, Caroline, Tomasini, Pascale

Source: Oncologist; Sep2024, Vol. 29 Issue 9, pe1180-e1188, 9p

Subject Terms: MELANOMA treatment, RETROSPECTIVE studies, DESCRIPTIVE statistics, MANN Whitney U Test, METASTASIS, LONGITUDINAL method, KAPLAN-Meier estimator, RESEARCH, INDIVIDUALIZED medicine, GENETIC mutation, TUMOR classification, DATA analysis software, MOLECULAR diagnosis

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine

Authors: Fanciullino, Raphaelle, Farnault, Laure, Donnette, Mélanie, Imbs, Diane-Charlotte, Roche, Catherine, Venton, Geoffroy, Berda-Haddad, Yael, Ivanov, Vadim, Ciccolini, Joseph, Ouafik, L'Houcine, Lacarelle, Bruno, Costello, Regis

Source: In Blood Advances 13 March 2018 2(5):462-469

Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiency

Authors: Gbeto, Crescent C, Quaranta, Sylvie, Mari, Roxane, Fanciullino, Raphaelle, Roche, Catherine, Nahon, Sophie, Solas, Caroline, Ouafik, L'Houcine, Lacarelle, Bruno, Allegre, Thierry, Ciccolini, Joseph

Source: Pharmacogenomics. 20(13):931-938

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186715458.0x000001&indx=1&recIds=ETOCvdc_100186715458.0x000001

Characteristics and Outcomes of Patients with Lung Cancer Harboring Multiple Molecular Alterations: Results from the IFCT Study Biomarkers France

Authors: Guibert, Nicolas, Barlesi, Fabrice, Descourt, Renaud, Léna, Hervé, Besse, Benjamin, Beau-Faller, Michèle, Mosser, Jean, Pichon, Eric, Merlio, Jean-Philippe, Ouafik, L'Houcine, Guichard, François, Mastroianni, Bénédicte, Moreau, Lionel, Wdowik, Annie, Sabourin, Jean-Christophe, Lemoine, Antoinette, Missy, Pascale, Langlais, Alexandra, Moro-Sibilot, Denis, Mazières, Julien

Source: In Journal of Thoracic Oncology June 2017 12(6):963-973

The landscape of cancer-associated transcript fusions in adult brain tumors: a longitudinal assessment in 140 patients with cerebral gliomas and brain metastases.

Authors: Metellus, Philippe, Camilla, Clara, Bialecki, Emilie, Beaufils, Nathalie, Vellutini, Christine, Pellegrino, Eric, Tomasini, Pascale, Ahluwalia, Manmeet S., Mansouri, Alireza, Nanni, Isabelle, Ouafik, L'Houcine

Source: Frontiers in Oncology; 2024, p1-17, 17p

Subject Terms: GENE fusion, BRAIN metastasis, PROTEIN-tyrosine kinases, NUCLEOTIDE sequencing, GLIOBLASTOMA multiforme, BRAIN tumors

Evidence of High Expression of Peptidylglycine α -amidating Monooxygenase in the Rat Uterus: Estrogen Regulation

Authors: El Meskini, Rajaa, Delfino, Christine, Boudouresque, Francoise, Oliver, Charles, Martin, Pierre-Marie, Ouafik, L'Houcine

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Jun 01. 95(12), 7191-7196.

Access URL: https://www.jstor.org/stable/45088

Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT)

Authors: Barlesi, Fabrice, Mazieres, Julien, Merlio, Jean-Philippe, Debieuvre, Didier, Mosser, Jean, Lena, Hervé, Ouafik, L'Houcine, Besse, Benjamin, Rouquette, Isabelle, Westeel, Virginie, Escande, Fabienne, Monnet, Isabelle, Lemoine, Antoinette, Veillon, Rémi, Blons, Hélène, Audigier-Valette, Clarisse, Bringuier, Pierre-Paul, Lamy, Régine, Beau-Faller, Michèle, Pujol, Jean-Louis, Sabourin, Jean-Christophe, Penault-Llorca, Frédérique, Denis, Marc G, Lantuejoul, Sylvie, Morin, Franck, Tran, Quân, Missy, Pascale, Langlais, Alexandra, Milleron, Bernard, Cadranel, Jacques, Soria, Jean-Charles, Zalcman, Gérard

Source: In The Lancet 2-8 April 2016 387(10026):1415-1426

Cytidine deaminase status as a marker of response to azacytidine treatment in MDS and AML patients.

Authors: Donnette, Melanie, Hamimed, Mourad, Ciccolini, Joseph, Sicard, Guillaume, Correard, Florian, Farnault, Laure, Ouafik, L'Houcine, Venton, Geoffroy, Fanciullino, Raphaëlle

Source: British Journal of Haematology; Nov2023, Vol. 203 Issue 4, p625-636, 12p

Subject Terms: CYTIDINE deaminase, ACUTE myeloid leukemia, AZACITIDINE, MYELODYSPLASTIC syndromes, INDUCTION chemotherapy

Plateformes de biologie moléculaire en oncologie thoracique : quelles recherches, pour qui ?

Alternate Title: Regional molecular genetics centers in thoracic oncology: what and who should be tested? (English)

Authors: Barlesi, Fabrice, Tomasini, Pascale, Fina, Frédéric, Secq, Véronique, Greillier, Laurent, Nanni-Metellus, Isabelle, Garcia, Stéphane, Ouafik, L'houcine

Source: In Bulletin du Cancer July-August 2013 100(7-8):737-741

Tubulin isoforms identified in the brain by MALDI in-source decay

Authors: Ait-Belkacem, Rima, Calligaris, David, Sellami, Lyna, Villard, Claude, Granjeaud, Samuel, Schembri, Thérèse, Berenguer, Caroline, Ouafik, L'Houcine, Figarella-Branger, Dominique, Chinot, Olivier, Lafitte, Daniel

Source: In Journal of Proteomics 21 February 2013 79:172-179

Yin and yang of cytidine deaminase roles in clinical response to azacitidine in the elderly: a pharmacogenetics tale

Authors: Fanciullino, Raphaelle, Mercier, Cédric, Serdjebi, Cindy, Venton, Geoffroy, Colle, Julien, Fina, Frédéric, Ouafik, L'Houcine, Lacarelle, Bruno, Ciccolini, Joseph, Costello, Régis

Source: Pharmacogenomics. 16(17):1907-1912

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127432132.0x000001&indx=1&recIds=ETOCvdc_100127432132.0x000001