Advances in Vaccines for Melanoma

Authors: Cui, Can, Ott, Patrick A., Wu, Catherine J.

Source: In Hematology/Oncology Clinics of North America October 2024 38(5):1045-1060

Neoantigen-directed therapeutics in the clinic: where are we?

Authors: Lybaert, Lien, Thielemans, Kris, Feldman, Steven A., van der Burg, Sjoerd H., Bogaert, Cedric, Ott, Patrick A.

Source: In Trends in Cancer June 2023 9(6):503-519

Latent Hierarchical Part Based Models for Road Scene Understanding

Authors: Venkateshkumar, Suhas Kashetty, Sridhar, Muralikrishna, Ott, Patrick

Source: 2015 IEEE International Conference on Computer Vision Workshop (ICCVW) Computer Vision Workshop (ICCVW), 2015 IEEE International Conference on. :115-123 Dec, 2015

Relation: 2015 IEEE International Conference on Computer Vision Workshop (ICCVW)

Challenges in neoantigen-directed therapeutics

Authors: Lybaert, Lien, Lefever, Steve, Fant, Bruno, Smits, Evelien, De Geest, Bruno, Breckpot, Karine, Dirix, Luc, Feldman, Steven A., van Criekinge, Wim, Thielemans, Kris, van der Burg, Sjoerd H., Ott, Patrick A., Bogaert, Cedric

Source: In Cancer Cell 9 January 2023 41(1):15-40

Targeting RAF1 gene fusions with MEK inhibition in metastatic melanoma.

Authors: Khaddour, Karam, Haq, Rizwan, Buchbinder, Elizabeth I, Liu, David, Manos, Michael P, Ott, Patrick A, Hodi, F Stephen, Insco, Megan L

Source: Oncologist; Mar2025, Vol. 30 Issue 3, p1-7, 7p

Subject Terms: THERAPEUTIC use of antineoplastic agents, VASCULAR endothelial growth factor antagonists, LIVER tumors, MITOGEN-activated protein kinases, PULMONARY embolism, MELANOMA, RESEARCH funding, RADIOPHARMACEUTICALS, DRUG side effects, GENETIC markers, DEOXY sugars, PROGRAMMED death-ligand 1, HOSPITAL care, CANCER patients, CELLULAR signal transduction, POSITRON emission tomography computed tomography, HEART failure, METASTASIS, DRUG efficacy, MEDICAL records, ACQUISITION of data, LUNG tumors, CARDIOTOXICITY, GENETIC mutation, NIVOLUMAB, RADIATION doses, DRUG eruptions, GENETICS, IPILIMUMAB, CHEMICAL inhibitors

Efficacy and safety of pembrolizumab for patients with previously treated advanced vulvar squamous cell carcinoma: Results from the phase 2 KEYNOTE-158 study

Authors: Shapira-Frommer, Ronnie, Mileshkin, Linda, Manzyuk, Ludmila, Penel, Nicolas, Burge, Matthew, Piha-Paul, Sarina A., Girda, Eugenia, Lopez Martin, Jose A., van Dongen, Marloes G.J., Italiano, Antoine, Xu, Lei, Jin, Fan, Norwood, Kevin, Ott, Patrick A.

Source: In Gynecologic Oncology August 2022 166(2):211-218

Pembrolizumab for previously treated advanced anal squamous cell carcinoma: results from the non-randomised, multicohort, multicentre, phase 2 KEYNOTE-158 study

Authors: Marabelle, Aurelien ^*, Cassier, Philippe A, Fakih, Marwan, Kao, Steven, Nielsen, Dorte, Italiano, Antoine, Guren, Tormod Kyrre, van Dongen, Marloes G J, Spencer, Kristen, Bariani, Giovanni Mendonca, Ascierto, Paolo A, Santoro, Armando, Shah, Manisha, Asselah, Jamil, Iqbal, Syma, Takahashi, Shunji, Piha-Paul, Sarina A, Ott, Patrick A, Chatterjee, Arkendu, Jin, Fan, Norwood, Kevin, Delord, Jean-Pierre

Source: In The Lancet Gastroenterology & Hepatology May 2022 7(5):446-454

Shared parts for deformable part-based models

Authors: Ott, Patrick, Everingham, Mark

Source: CVPR 2011 Computer Vision and Pattern Recognition (CVPR), 2011 IEEE Conference on. :1513-1520 Jun, 2011

Relation: 2011 IEEE Conference on Computer Vision and Pattern Recognition (CVPR)

Implicit color segmentation features for pedestrian and object detection

Authors: Ott, Patrick, Everingham, Mark

Source: 2009 IEEE 12th International Conference on Computer Vision Computer Vision, 2009 IEEE 12th International Conference on. :723-730 Sep, 2009

Relation: 2009 IEEE 12th International Conference on Computer Vision (ICCV)

A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant

Authors: Murakami, Naoka, Mulvaney, Patrick, Danesh, Melissa, Abudayyeh, Ala, Diab, Adi, Abdel-Wahab, Noha, Abdelrahim, Maen, Khairallah, Pascale, Shirazian, Shayan, Kukla, Aleksandra, Owoyemi, Itunu O., Alhamad, Tarek, Husami, Samir, Menon, Madhav, Santeusanio, Andrew, Blosser, Christopher D., Zuniga, Sandra Carias, Soler, Maria Jose, Moreso, Francesc, Mithani, Zain, Ortiz-Melo, David, Jaimes, Edgar A., Gutgarts, Victoria, Lum, Erik, Danovitch, Gabriel M., Cardarelli, Francesca, Drews, Reed E., Bassil, Claude, Swank, Jennifer L., Westphal, Scott, Mannon, Roslyn B., Shirai, Keisuke, Kitchlu, Abhijat, Ong, Song, Machado, Shana M., Mothi, Suraj S., Ott, Patrick A., Rahma, Osama, Hodi, F. Stephen, Sise, Meghan E., Gupta, Shruti, Leaf, David E., Devoe, Craig E., Wanchoo, Rimda, Nair, Vinay V., Schmults, Chrysalyne D., Hanna, Glenn J., Sprangers, Ben, Riella, Leonardo V., Jhaveri, Kenar D.

Source: In Kidney International July 2021 100(1):196-205

Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples

Authors: Klaeger, Susan, Apffel, Annie, Clauser, Karl R., Sarkizova, Siranush, Oliveira, Giacomo, Rachimi, Suzanna, Le, Phuong M., Tarren, Anna, Chea, Vipheaviny, Abelin, Jennifer G., Braun, David A., Ott, Patrick A., Keshishian, Hasmik, Hacohen, Nir, Keskin, Derin B., Wu, Catherine J., Carr, Steven A.

Source: In Molecular & Cellular Proteomics 2021 20

A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer

Authors: Ott, Patrick A., Hu-Lieskovan, Siwen, Chmielowski, Bartosz, Govindan, Ramaswamy, Naing, Aung, Bhardwaj, Nina, Margolin, Kim, Awad, Mark M., Hellmann, Matthew D., Lin, Jessica J., Friedlander, Terence, Bushway, Meghan E., Balogh, Kristen N., Sciuto, Tracey E., Kohler, Victoria, Turnbull, Samantha J., Besada, Rana, Curran, Riley R., Trapp, Benjamin, Scherer, Julian, Poran, Asaf, Harjanto, Dewi, Barthelme, Dominik, Ting, Ying Sonia, Dong, Jesse Z., Ware, Yvonne, Huang, Yuting, Huang, Zhengping, Wanamaker, Amy, Cleary, Lisa D., Moles, Melissa A., Manson, Kelledy, Greshock, Joel, Khondker, Zakaria S., Fritsch, Ed, Rooney, Michael S., DeMario, Mark, Gaynor, Richard B., Srinivasan, Lakshmi

Source: In Cell 15 October 2020 183(2):347-362

Single-Step Synthesis of Atmospheric CO₂ Sorbents through Radiation-Induced Graft Polymerization on Commercial-Grade Fabrics

Authors: Fastow, Eli, Cook, Sean, Dean, Pablo, Ott, Patrick, Wilson, Jonathan, Yoon, Hojin, Dietz, Travis, Bateman, Fred, Al-Sheikhly, Mohamad

Source: Radiation Research, 2019 Aug 01. 192(2), 219-230.

Access URL: https://www.jstor.org/stable/48570533

Pembrolizumab After Two or More Lines of Previous Therapy in Patients With Recurrent or Metastatic SCLC: Results From the KEYNOTE-028 and KEYNOTE-158 Studies

Authors: Chung, Hyun Cheol, Piha-Paul, Sarina A., Lopez-Martin, Jose, Schellens, Jan H.M., Kao, Steven, Miller, Wilson H., Jr., Delord, Jean-Pierre, Gao, Bo, Planchard, David, Gottfried, Maya, Zer, Alona, Jalal, Shadia I., Penel, Nicolas, Mehnert, Janice M., Matos, Ignacio, Bennouna, Jaafar, Kim, Dong-Wan, Xu, Lei, Krishnan, Suba, Norwood, Kevin, Ott, Patrick A.

Source: In Journal of Thoracic Oncology April 2020 15(4):618-627

Nivolumab Monotherapy and Nivolumab Plus Ipilimumab in Recurrent Small Cell Lung Cancer: Results From the CheckMate 032 Randomized Cohort

Authors: Ready, Neal E., Ott, Patrick A., Hellmann, Matthew D., Zugazagoitia, Jon, Hann, Christine L., de Braud, Filippo, Antonia, Scott J., Ascierto, Paolo A., Moreno, Victor, Atmaca, Akin, Salvagni, Stefania, Taylor, Matthew, Amin, Asim, Camidge, D. Ross, Horn, Leora, Calvo, Emiliano, Li, Ang, Lin, Wen Hong, Callahan, Margaret K., Spigel, David R.

Source: In Journal of Thoracic Oncology March 2020 15(3):426-435

Real-world Treatment Patterns and Clinical Outcomes Across Lines of Therapy in Patients With Advanced/Metastatic Gastric or Gastroesophageal Junction Cancer

Authors: Le, Dung T., Ott, Patrick A., Korytowsky, Beata, Le, Hannah, Le, T. Kim, Zhang, Ying, Maglinte, Gregory A., Abraham, Pranav, Patel, Dhiren, Shangguan, Tong, Chau, Ian

Source: In Clinical Colorectal Cancer March 2020 19(1):32-38

Detection of Partially Visible Objects

Authors: Ott, Patrick, Everingham, Mark, Matas, Jiri

Subject Terms: Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/1311.6758

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

Authors: Braun, David A., Moranzoni, Giorgia, Chea, Vipheaviny, McGregor, Bradley A., Blass, Eryn, Tu, Chloe R., Vanasse, Allison P., Forman, Cleo, Forman, Juliet, Afeyan, Alexander B., Schindler, Nicholas R., Liu, Yiwen, Li, Shuqiang, Southard, Jackson, Chang, Steven L., Hirsch, Michelle S., LeBoeuf, Nicole R., Olive, Oriol, Mehndiratta, Ambica, Greenslade, Haley, Shetty, Keerthi, Klaeger, Susan, Sarkizova, Siranush, Pedersen, Christina B., Mossanen, Matthew, Carulli, Isabel, Tarren, Anna, Duke-Cohan, Joseph, Howard, Alexis A., Iorgulescu, J. Bryan, Shim, Bohoon, Simon, Jeremy M., Signoretti, Sabina, Aster, Jon C., Elagina, Liudmila, Carr, Steven A., Leshchiner, Ignaty, Getz, Gad, Gabriel, Stacey, Hacohen, Nir, Olsen, Lars R., Oliveira, Giacomo, Neuberg, Donna S., Livak, Kenneth J., Shukla, Sachet A., Fritsch, Edward F., Wu, Catherine J., Keskin, Derin B., Ott, Patrick A., Choueiri, Toni K.

Source: Nature; 20250101, Issue: Preprints p1-9, 9p

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial

Authors: Lopez, Juanita, Powles, Thomas, Braiteh, Fadi, Siu, Lillian L., LoRusso, Patricia, Friedman, Claire F., Balmanoukian, Ani S., Gordon, Michael, Yachnin, Jeffrey, Rottey, Sylvie, Karydis, Ioannis, Fisher, George A., Schmidt, Marcus, Schuler, Martin, Sullivan, Ryan J., Burris, Howard A., Galvao, Vladimir, Henick, Brian S., Dirix, Luc, Jaeger, Dirk, Ott, Patrick A., Wong, Kit Man, Jerusalem, Guy, Schiza, Aglaia, Fong, Lawrence, Steeghs, Neeltje, Leidner, Rom S., Rittmeyer, Achim, Laurie, Scott A., Gort, Eelke, Aljumaily, Raid, Melero, Ignacio, Sabado, Rachel L., Rhee, Ina, Mancuso, Michael R., Muller, Lars, Fine, Gregg D., Yadav, Mahesh, Kim, Leesun, Leveque, Vincent J. P., Robert, Alberto, Darwish, Martine, Qi, Ting, Zhu, Jiawen, Zhang, Jingbin, Twomey, Patrick, Rao, Gautham K., Low, Donald W., Petry, Chris, Lo, Amy A., Schartner, Jill M., Delamarre, Lélia, Mellman, Ira, Löwer, Martin, Müller, Felicitas, Derhovanessian, Evelyna, Cortini, Andrea, Manning, Luisa, Maurus, Daniel, Brachtendorf, Sebastian, Lörks, Verena, Omokoko, Tana, Godehardt, Eva, Becker, Dirk, Hawner, Christine, Wallrapp, Christine, Albrecht, Christian, Kröner, Christoph, Tadmor, Arbel D., Diekmann, Jan, Vormehr, Mathias, Jork, Anette, Paruzynski, Anna, Lang, Maren, Blake, Jonathon, Hennig, Oliver, Kuhn, Andreas N., Sahin, Ugur, Türeci, Özlem, Camidge, D. Ross

Source: Nature Medicine; 20250101, Issue: Preprints p1-13, 13p

Intralesional Cancer Immunotherapies

Authors: Ott, Patrick A.

Source: In Hematology/Oncology Clinics of North America April 2019 33(2):249-260