A method for assessing and monitoring consistency of nonclinical ECG analysis

Authors: Ross, Rebecca A., Foley, C. Michael, Jones, Hilton M., Osinski, Mark A.

Source: In Journal of Pharmacological and Toxicological Methods July-August 2022 116

Activation of Dopamine D4 Receptors by ABT-724 Induces Penile Erection in Rats

Authors: Brioni, Jorge D., Moreland, Robert B., Cowart, Marlon, Hsieh, Gin C., Stewart, Andrew O., Hedlund, Petter, Donnelly-Roberts, Diana L., Nakane, Masaki, Lynch,, James J., Kolasa, Teodozyi, Polakowski, James S., Osinski, Mark A., Marsh, Kennan, Andersson, Karl-Erik, Sullivan, James P., Beavo, Joseph A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Apr . 101(17), 6758-6763.

Access URL: https://www.jstor.org/stable/3372156

Evaluation of cardiovascular changes in dogs administered three positive controls using jacketed external telemetry-blood pressure (JET-BP)

Authors: Kremer, John J., Bills, Andrew J., Hanke, Nathanael J., Chen, Hepei, Meier, William A., Osinski, Mark A., Foley, C. Michael

Source: In Journal of Pharmacological and Toxicological Methods September-October 2015 75:27-37

Intravenous solid tip ECG lead placement in telemetry implanted dogs: Part 2: High quality telemetry signals yield high sensitivity to drug-induced changes

Authors: Mitchell, Andrea Z., Bills, Andrew J., Wittwer, Gary T., Foley, C. Michael, Kremer, John J., Chen, Hepei, Osinski, Mark A.

Source: In Journal of Pharmacological and Toxicological Methods July-August 2013 68(1):62-73

Intravenous solid tip lead placement in telemetry implanted dogs. Part 1: Surgical methods, signal quality, and pathological endpoints

Authors: Walisser, Jacqueline A., Mitchell, Andrea Z., Bills, Andrew J., Sharma, Alok K., Latimer, Kenneth, Taschwer, Michael, Osinski, Mark A.

Source: In Journal of Pharmacological and Toxicological Methods July-August 2013 68(1):52-61

Su1739 SAFETY PHARMACOLOGY EVALUATIONS OF TAK-906, A NOVEL DOPAMINE D2/D3 SELECTIVE RECEPTOR ANTAGONIST FOR THE MANAGEMENT OF GASTROPARESIS

Authors: Kreckler, Laura, Osinski, Mark, Williams, Scott, Whiting, Roger

Source: Gastroenterology. 158(6):S-627-S-628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131730746.0x000001&indx=1&recIds=ETOCvdc_100131730746.0x000001

Pharmacological MRI in awake rats reveals neural activity in area postrema and nucleus tractus solitarius: Relevance as a potential biomarker for detecting drug-induced emesis

Authors: Chin, Chih-Liang, Fox, Gerard B., Hradil, Vincent P., Osinski, Mark A., McGaraughty, Steve P., Skoubis, Pamela D., Cox, Bryan F., Luo, Yanping

Source: In NeuroImage December 2006 33(4):1152-1160

Predictive, non-GLP models of secondary pharmacodynamics: putting the best compounds forward

Authors: Reinhart, Glenn A, Fryer, Ryan M, Osinski, Mark A, Polakowski, James S, Cox, Bryan F, Gintant, Gary A

Source: In Current Opinion in Chemical Biology 2005 9(4):392-399

Dopamine D 2, but not D 4, receptor agonists are emetogenic in ferrets

Authors: Osinski, Mark A., Uchic, Marie E., Seifert, Terese, Shaughnessy, Thomas K., Miller, Loan N., Nakane, Masaki, Cox, Bryan F., Brioni, Jorge D., Moreland, Robert B.

Source: In Pharmacology, Biochemistry and Behavior 2005 81(1):211-219

Non-Clinical Safety Pharmacology Evaluations of Trazpiroben (TAK-906), a Novel Dopamine D2/D3 Selective Receptor Antagonist for the Management of Gastroparesis.

Authors: Kreckler, Laura (AUTHOR), Osinski, Mark (AUTHOR), Williams, Scott (AUTHOR), Whiting, Roger (AUTHOR)

Source: Journal of Experimental Pharmacology. Feb2022, Vol. 14, p43-57. 15p.

Subject Terms: *GASTROPARESIS, *BEAGLE (Dog breed), *CENTRAL nervous system, *BODY temperature, *PHARMACOLOGY, *CARDIOVASCULAR system

Throttle control for automated mechanical transmission

Torque converter slip rate-based torque converter lock-up strategy

Mechanisms of altered smooth muscle responsiveness in a rodent model of intestinal denevation

Authors: Osinski, Mark A.

Access URL: http://hdl.handle.net/2027/wu.89052199502

Expression of nociceptin/OFQ receptor and prepro-nociceptin/OFQ in lymphoid tissues

Authors: Pampusch, Mary S., Serie, Janet R., Osinski, Mark A., Seybold, Virginia S., Murtaugh, Michael P., Brown, David R. ^*

Source: In Peptides 2000 21(12):1865-1870

Orphanin FQ/nociceptin: a novel neuromodulator of gastrointestinal function?

Authors: Osinski, Mark A, Brown, David R ^*

Source: In Peptides 2000 21(7):999-1005

Assessment of electrocardiography (ECG) parameter variability when building ECG template libraries

Authors: Ross, Rebecca, Kremer, John, Aschcroft-Hawley, Kelly, Michael Foley, C., Osinski, Mark, Carneal-Frazer, Nicole

Source: Journal of pharmacological and toxicological methods. 81:368-369

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096897429.0x000001&indx=1&recIds=ETOCvdc_100096897429.0x000001

Cloning, expression and functional role of a nociceptin/orphanin FQ receptor in the porcine gastrointestinal tract

Authors: Osinski, Mark A., Pampusch, Mary S., Murtaugh, Michael P., Brown, David R. ^*

Source: In European Journal of Pharmacology 1999 365(2):281-289

Echocardiography Group Size Requirements in Canine Toxicology Studies Based on Power Analysis

Authors: Kremer, John, Ashcroft-Hawley, Kelly, Carneal-Frazer, Nicole, Harrison, Rachael, Bari Olivier, N., Osinski, Mark

Source: Journal of pharmacological and toxicological methods. 88(2):228-228

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061386643.0x000001&indx=1&recIds=ETOCvdc_100061386643.0x000001

Assessment of Analyst Consistency in Marking Electrocardiograms (ECGs)

Authors: Ross, Rebecca, Jones, Hilton, Osinski, Mark

Source: Journal of pharmacological and toxicological methods. 88(2):224-224

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061386596.0x000001&indx=1&recIds=ETOCvdc_100061386596.0x000001

Assessment of Electrocardiography (ECG) Parameter Variability when Building ECG Template Libraries from Implanted Telemetry Devices

Authors: Ross, Rebecca, Kremer, John, Garske, Eric, Hommola, Kerstin, Ashcroft-Hawley, Kelly, Osinski, Mark

Source: Journal of pharmacological and toxicological methods. 88(2):224-224

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061386556.0x000001&indx=1&recIds=ETOCvdc_100061386556.0x000001