CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles

Authors: Osawa, Hinata, Kurohara, Takashi, Ito, Takahito, Shibata, Norihito, Demizu, Yosuke

Source: In Bioorganic & Medicinal Chemistry 15 April 2023 84

Structure–activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthaseElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00284a

Authors: Murakami, Yuki, Osawa, Hinata, Kurohara, Takashi, Yanase, Yuta, Ito, Takahito, Yokoo, Hidetomo, Shibata, Norihito, Naito, Mikihiko, Aritake, Kosuke, Demizu, Yosuke

Source: RSC medicinal chemistry. 13(12):1495-1503

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168310515.0x000001&indx=1&recIds=ETOCvdc_100168310515.0x000001

Structure–activity relationship study of PROTACs against hematopoietic prostaglandin D2synthaseElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00284a

Authors: Murakami, Yuki, Osawa, Hinata, Kurohara, Takashi, Yanase, Yuta, Ito, Takahito, Yokoo, Hidetomo, Shibata, Norihito, Naito, Mikihiko, Aritake, Kosuke, Demizu, Yosuke

Source: MedChemComm; 2022, Vol. 13 Issue: 12 p1495-1503, 9p