SMN2 gene copy number affects the incidence and prognosis of motor neuron diseases in Japan

Authors: Tomohiko Ishihara, Akihide Koyama, Naoki Atsuta, Mari Tada, Saori Toyoda, Kenta Kashiwagi, Sachiko Hirokawa, Yuya Hatano, Akio Yokoseki, Ryoichi Nakamura, Genki Tohnai, Yuishin Izumi, Ryuji Kaji, Mitsuya Morita, Asako Tamura, Osamu Kano, Masashi Aoki, Satoshi Kuwabara, Akiyoshi Kakita, Gen Sobue, Osamu Onodera

Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-7 (2024)

Subject Terms: ALS, SMA, LMND, SMN, Copy number status, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/e6002aa4b2cd48bbb9179f2fb1b1a195

Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale

Authors: Masaru Yanagihashi, Takehisa Hirayama, Mari Shibukawa, Junpei Nagasawa, Koji Fujita, Yuishin Izumi, Mitsuya Morita, Kota Bokuda, Kazushi Takahashi, Kazuaki Kanai, Naoki Atsuta, Yohei Iguchi, Masahisa Katsuno, Yoshitaka Murakami, Hiroshi Mitsumoto, Osamu Kano

Source: BMC Neurology, Vol 24, Iss 1, Pp 1-4 (2024)

Subject Terms: Primary lateral sclerosis, PLSFRS Japanese version, Face-to-face assessments, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/ae86317d1da7451ebdde2298aecee970

Protocol for a phase 2 study of bosutinib for amyotrophic lateral sclerosis using real-world data: induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (iDReAM) study

Authors: Gen Sobue, Hirofumi Maruyama, Keiko Imamura, Yuishin Izumi, Satoshi Morita, Naohiro Egawa, Takashi Ayaki, Makiko Nagai, Kazutoshi Nishiyama, Yasuhiro Watanabe, Ritsuko Hanajima, Koji Fujita, Naoto Takahashi, Akiko Morinaga, Ryosuke Takahashi, Haruhisa Inoue, Naoki Atsuta, Osamu Kano, Takehisa Hirayama, Takao Kiriyama, Hiroshi Kataoka, Takahiko Tokuda, Kazuma Sugie, Takenobu Murakami, Hitoki Nanaura, Masahiro Nakamori, Shotaro Haji, Harutsugu Tatebe, Riko Tabuchi, Motoki Oe, Mihoko Kobayashi, Kasia Lobello

Source: BMJ Open, Vol 14, Iss 10 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/10/e082142.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/63d3495d00e24d60a205cd5377da8720

Impact of Istradefylline on Levodopa Dose Escalation in Parkinson’s Disease: ISTRA ADJUST PD Study, a Multicenter, Open-Label, Randomized, Parallel-Group Controlled Study

Authors: Taku Hatano, Renpei Sengoku, Hiroshi Nagayama, Naotake Yanagisawa, Asako Yoritaka, Keisuke Suzuki, Noriko Nishikawa, Yohei Mukai, Kyoichi Nomura, Norihito Yoshida, Morinobu Seki, Miho Kawabe Matsukawa, Hiroo Terashi, Katsuo Kimura, Jun Tashiro, Shigeki Hirano, Hidetomo Murakami, Hideto Joki, Tsuyoshi Uchiyama, Hideki Shimura, Kotaro Ogaki, Jiro Fukae, Yoshio Tsuboi, Kazushi Takahashi, Toshimasa Yamamoto, Kenichi Kaida, Ryoko Ihara, Kazutomi Kanemaru, Osamu Kano

Source: Neurology and Therapy, Vol 13, Iss 2, Pp 323-338 (2024)

Subject Terms: Adenosine A2A receptor antagonist, Istradefylline, Levodopa, Levodopa dose, Parkinson’s disease, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8253; https://doaj.org/toc/2193-6536

Access URL: https://doaj.org/article/297912391b29425383cd3fe2f9e7b7d9

Comparison of MIBG uptake in the major salivary glands between Lewy body disease and progressive supranuclear palsy

Authors: Junya Ebina, Sunao Mizumura, Mari Shibukawa, Harumi Morioka, Junpei Nagasawa, Masaru Yanagihashi, Takehisa Hirayama, Nobutomo Ishii, Yukio Kobayashi, Akira Inaba, Satoshi Orimo, Osamu Kano

Source: Clinical Parkinsonism & Related Disorders, Vol 11, Iss , Pp 100287- (2024)

Subject Terms: Parkinson’s disease, Dementia with Lewy bodies, Progressive supranuclear palsy, MIBG scintigraphy, Major salivary glands, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590112524000586; https://doaj.org/toc/2590-1125

Access URL: https://doaj.org/article/23c4b2dad5434770a1b9a5e05c059d05

Improving taste sensitivity in healthy adults using taste recall training: a randomized controlled trial

Authors: Yuta Otsubo, Midori Miyagi, Hideki Sekiya, Osamu Kano, Satoru Ebihara

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/48d78263d79e4104b86e9e51aeed40ab

Detection of Atrial Fibrillation Using Insertable Cardiac Monitors in Patients With Cryptogenic Stroke in Japan (the LOOK Study): Protocol for a Prospective Multicenter Observational Study

Authors: Satoshi Suda, Takehiro Katano, Kazuo Kitagawa, Yasuyuki Iguchi, Shigeru Fujimoto, Kenjiro Ono, Osamu Kano, Hidehiro Takekawa, Masatoshi Koga, Masafumi Ihara, Masafumi Morimoto, Hiroshi Yamagami, Tadashi Terasaki, Keiji Yamaguchi, Seiji Okubo, Yuji Ueno, Nobuyuki Ohara, Yuki Kamiya, Masataka Takeuchi, Yukako Yazawa, Yuka Terasawa, Ryosuke Doijiri, Yoshifumi Tsuboi, Kazutaka Sonoda, Koichi Nomura, Takashi Shimoyama, Akihito Kutsuna, Kazumi Kimura

Source: JMIR Research Protocols, Vol 12, p e39307 (2023)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2023/1/e39307; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/b66479d29e3c483392ed77958a93196f

Evaluating the impact of adjunctive istradefylline on the cumulative dose of levodopa-containing medications in Parkinson’s disease: study protocol for the ISTRA ADJUST PD randomized, controlled study

Authors: Taku Hatano, Osamu Kano, Renpei Sengoku, Asako Yoritaka, Keisuke Suzuki, Noriko Nishikawa, Yohei Mukai, Kyoichi Nomura, Norihito Yoshida, Morinobu Seki, Miho Kawabe Matsukawa, Hiroo Terashi, Katsuo Kimura, Jun Tashiro, Shigeki Hirano, Hidetomo Murakami, Hideto Joki, Tsuyoshi Uchiyama, Hideki Shimura, Kotaro Ogaki, Jiro Fukae, Yoshio Tsuboi, Kazushi Takahashi, Toshimasa Yamamoto, Naotake Yanagisawa, Hiroshi Nagayama

Source: BMC Neurology, Vol 22, Iss 1, Pp 1-9 (2022)

Subject Terms: Istradefylline, Parkinson’s disease, Adenosine A2A receptor antagonist, Levodopa, Levodopa dose, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/05704b3d790741498c68e0d164b8370b

Coronary spastic angina after the administration of intravenous immunoglobulin in myasthenia gravis: a case report

Authors: Masaru Yanagihashi, Ryuichi Okamoto, Harumi Morioka, Masahiro Sawada, Shingo Matsumoto, Takanori Ikeda, Osamu Kano

Source: BMC Neurology, Vol 20, Iss 1, Pp 1-4 (2020)

Subject Terms: Coronary spastic angina (CSA), Intravenous immunoglobulin (IVIG), Myasthenia gravis (MG), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12883-020-01901-2; https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/f420c7c4a14449779046801a670f7c8d

Rasagiline as Adjunct to Levodopa for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis

Authors: Osamu Kano, Hiroshi Tsuda, Ayako Hayashi, Masaki Arai

Source: Parkinson's Disease, Vol 2022 (2022)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2042-0080

Access URL: https://doaj.org/article/edbd91f833c24c69b4423b4c408f5bf7

Levodopa-Responsive Benign Tremulous Parkinsonism

Authors: Osamu Kano, Shinichi Okonogi, Sayori Hanashiro, Ken Miura, Ken Ikeda, Yasuo Iwasaki

Source: Case Reports in Neurology, Vol 5, Iss 2, Pp 139-142 (2013)

Subject Terms: Rest tremor, Essential tremor, Levodopa, Parkinson’s disease, Benign tremulous parkinsonism, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.karger.com/Article/FullText/354980; https://doaj.org/toc/1662-680X

Access URL: https://doaj.org/article/b72de0e028ea4da2af844fdcb4fbed69

Beneficial effect of pramipexole for motor function and depression in Parkinson’s disease

Authors: Osamu Kano, Ken Ikeda, Tetsuhito Kiyozuka, Konosuke Iwamoto, Hirono Ito, et al

Source: Neuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 4, Pp 707-710 (2009)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.dovepress.com/beneficial-effect-of-pramipexole-for-motor-function-and-depression-in--a2868; https://doaj.org/toc/1176-6328; https://doaj.org/toc/1178-2021

Access URL: https://doaj.org/article/3b0f1bb172eb465f8aefe58e95819398

Investigation of Metabolism of Exogenous Glucose at the Early Stage and Onset of Diabetes Mellitus in Otsuka Long-Evans Tokushima Fatty Rats Using [1, 2, 3-13C]Glucose Breath Tests.

Authors: Naoyuki Kawagoe, Osamu Kano, Sho Kijima, Hideki Tanaka, Masaaki Takayanagi, Yoshihisa Urita

Source: PLoS ONE, Vol 11, Iss 8, p e0160177 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4970713?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/82ef762b391b4e73882e2045848c1b76

Neurobiology of Depression and Anxiety in Parkinson's Disease

Authors: Osamu Kano, Ken Ikeda, Derek Cridebring, Takanori Takazawa, Yasuhiro Yoshii, Yasuo Iwasaki

Source: Parkinson's Disease, Vol 2011 (2011)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2042-0080

Access URL: https://doaj.org/article/5f941ec73996416b88e95d7f65bc649f

Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients.

Authors: Ryoichi Nakamura, Genki Tohnai, Masahiro Nakatochi, Naoki Atsuta, Hirohisa Watanabe, Daisuke Ito, Masahisa Katsuno, Akihiro Hirakawa, Yuishin Izumi, Mitsuya Morita, Takehisa Hirayama, Osamu Kano, Kazuaki Kanai, Nobutaka Hattori, Akira Taniguchi, Naoki Suzuki, Masashi Aoki, Ikuko Iwata, Ichiro Yabe, Kazumoto Shibuya

Source: Journal of Neurology, Neurosurgery & Psychiatry; Oct2023, Vol. 94 Issue 10, p816-824, 9p

Subject Terms: AMYOTROPHIC lateral sclerosis, GENOME-wide association studies, MOTOR neurons, JAPANESE people, OVERALL survival, CELL death, DELAYED onset of disease

Association between middle cerebral artery morphology and branch atheromatous disease.

Authors: Junpei Nagasawa, Kenichi Suzuki, Sayori Hanashiro, Masaru Yanagihashi, Takehisa Hirayama, Masaaki Hori, Osamu Kano

Source: Journal of Medical Investigation; 2023, Vol. 70 Issue 3/4, p411-414, 4p

Subject Terms: CEREBRAL artery physiology, CEREBRAL infarction, BLOOD flow, SHEARING force, DATA analysis

The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.

Authors: Satoshi Yokoi, Takuji Ito, Kentaro Sahashi, Masahiro Nakatochi, Ryoichi Nakamura, Genki Tohnai, Yusuke Fujioka, Shinsuke Ishigaki, Tsuyoshi Udagawa, Yuishin Izumi, Mitsuya Morita, Osamu Kano, Masaya Oda, Takefumi Sone, Hideyuki Okano, Naoki Atsuta, Masahisa Katsuno, Yohei Okada, Gen Sobue

Source: Journal of Neuroscience; 11/23/2022, Vol. 42 Issue 47, p8881-8896, 16p

Subject Terms: DENDRITIC spines, MOTOR neurons, AMYOTROPHIC lateral sclerosis, RNA-binding proteins, PLURIPOTENT stem cells

Geographic Terms: JAPAN

Effects of Long-term Hybrid Assistive Limb Use on Gait in Patients with Amyotrophic Lateral Sclerosis.

Authors: Harumi Morioka, Kiyoko Murata, Tatsuki Sugisawa, Mari Shibukawa, Junya Ebina, Masahiro Sawada, Sayori Hanashiro, Junpei Nagasawa, Masaru Yanagihashi, Takehisa Hirayama, Masayuki Uchi, Kiyokazu Kawabe, Satoru Ebihara, Yoshitaka Murakami, Takashi Nakajima, Osamu Kano

Source: Internal Medicine; 2022, Vol. 61 Issue 10, p1479-1484, 6p

Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) with atypical encephalitis and painful testitis: a case report.

Authors: Hidenori Kido¹ hidenori775@gmail.com, Osamu Kano², Asami Hamai¹, Hiroyuki Masuda³, Yutaka Fuchinoue³, Masaaki Nemoto³, Chiaki Arai⁴, Teppei Takeda⁴, Fumihito Yamabe⁵, Toshihiro Tai⁵, Mizuki Kasahara⁵, Kenichi Suzuki⁶, Nobuyuki Shiraga⁶, Sota Sadamoto⁷, Megumi Wakayama⁷, Yukitoshi Takahashi⁸, Yasuo Iwasaki², Kazutoshi Shibuya⁷, Yoshihisa Urita¹, Kido, Hidenori⁹ (AUTHOR)

Source: BMC Neurology. 2/1/2017, Vol. 17, p1-5. 5p. 2 Color Photographs, 2 Black and White Photographs.

Subject Terms: *LYMPHADENITIS, *ENCEPHALITIS, *INFLAMMATION, *LYMPHATIC diseases, *BRAIN diseases, *MACROPHAGES, *PAIN, *TESTICULAR diseases, *DISEASE complications

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