Purposing plant-derived exosomes-like nanovesicles for drug delivery: patents and literature review

Authors: Orefice, Nicola Salvatore, Di Raimo, Rossella, Mizzoni, Davide, Logozzi, Mariantonia, Fais, Stefano

Source: Expert opinion on therapeutic patents. 33(2):89-100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179787633.0x000001&indx=1&recIds=ETOCvdc_100179787633.0x000001

The Importance of Detecting, Quantifying, and Characterizing Exosomes as a New Diagnostic/Prognostic Approach for Tumor Patients.

Authors: Logozzi, Mariantonia¹ (AUTHOR) mariantonia.logozzi@iss.it, Orefice, Nicola Salvatore² (AUTHOR) nicola.orefice@northwestern.edu, Di Raimo, Rossella³ (AUTHOR) rossella@exolabitalia.com, Mizzoni, Davide³ (AUTHOR) davide@exolabitalia.com, Fais, Stefano¹ (AUTHOR) stefano.fais@iss.it

Source: Cancers. Jun2023, Vol. 15 Issue 11, p2878. 21p.

Subject Terms: *TUMOR diagnosis, *PROTEIN metabolism, *FLOW cytometry, *EXOSOMES, *HYDROGEN-ion concentration, *CANCER patients, *ENZYME-linked immunosorbent assay, *TUMOR markers, *TUMORS, *NUCLEIC acids, *NANOPARTICLES

Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

Authors: Orefice, Nicola Salvatore, Souchet, Benoît, Braudeau, Jérôme, Alves, Sandro, Piguet, Françoise, Collaud, Fanny, Ronzitti, Giuseppe, Tada, Satoru, Hantraye, Philippe, Mingozzi, Federico, Ducongé, Frédéric, Cartier, Nathalie

Source: In Molecular Therapy - Methods & Clinical Development 13 September 2019 14:237-251

Integrated Label-Free and 10-Plex DiLeu Isobaric Tag Quantitative Methods for Profiling Changes in the Mouse Hypothalamic Neuropeptidome and Proteome: Assessment of the Impact of the Gut Microbiome

Authors: Liu, Rui, Wei, Pingli, Keller, Caitlin, Orefice, Nicola Salvatore, Shi, Yatao, Li, Zihui, Huang, Junfeng, Cui, Yusi, Frost, Dustin C., Han, Shuying

Source: Analytical chemistry. 92(20):14021-14030

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625160052&indx=1&recIds=ETOCRN625160052

Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery.

Authors: N'Diaye, Elisa-Racky¹ (AUTHOR) elisa-racky.n-diaye@etu-univ-grenoble-alpes.fr, Orefice, Nicola Salvatore² (AUTHOR) nicola.orefice@univ-grenoble-alpes.fr, Ghezzi, Catherine² (AUTHOR) catherine.ghezzi@univ-grenoble-alpes.fr, Boumendjel, Ahcène² (AUTHOR) ahcene.boumendjel@univ-grenoble-alpes.fr

Source: Pharmaceutics. Mar2022, Vol. 14 Issue 3, p653. 15p.

Subject Terms: *POLYMERSOMES, *EXTRACELLULAR vesicles, *RADIOLABELING, *DRUG delivery systems, *NANOCARRIERS

Galactosyl prodrug of palmitoylethanolamide: Synthesis, stability, cell permeation and cytoprotective activity

Authors: Luongo, Elvira, Russo, Roberto, Avagliano, Carmen, Santoro, Anna, Melisi, Daniela, Orefice, Nicola Salvatore, Raso, Giuseppina Mattace, Meli, Rosaria, Magliocca, Salvatore, Nieddu, Maria, Santiago, Gilvandete Maria Pinheiro, Boatto, Gianpiero, Calignano, Antonio, Rimoli, Maria Grazia

Source: In European Journal of Pharmaceutical Sciences 1 October 2014 62:33-39

N-Palmitoylethanolamide protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress

Authors: Mattace Raso, Giuseppina, Simeoli, Raffaele, Russo, Roberto, Santoro, Anna, Pirozzi, Claudio, d’Emmanuele di Villa Bianca, Roberta, Mitidieri, Emma, Paciello, Orlando, Pagano, Teresa Bruna, Orefice, Nicola Salvatore, Meli, Rosaria, Calignano, Antonio

Source: In Pharmacological Research October 2013 76:67-76

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

Authors: Souchet, Benoît, Audrain, Mickael, Billard, Jean Marie, Dairou, Julien, Fol, Romain, Orefice, Nicola Salvatore, Tada, Satoru, Gu, Yuchen, Dufayet-Chaffaud, Gaelle, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Alves, Sandro, Meijer, Laurent, Janel, Nathalie, Braudeau, Jérôme, Cartier, Nathalie

Source: Acta neuropathologica communications. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130969701.0x000001&indx=1&recIds=ETOCvdc_100130969701.0x000001

Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology.

Authors: Rigby, Michael J^1,2,3 (AUTHOR), Orefice, Nicola Salvatore^1,2 (AUTHOR), Lawton, Alexis J⁴ (AUTHOR), Ma, Min⁵ (AUTHOR), Shapiro, Samantha L^1,2 (AUTHOR), Yi, Sue Y³ (AUTHOR), Dieterich, Inca A^1,2,3 (AUTHOR), Frelka, Alyssa⁶ (AUTHOR), Miles, Hannah N⁵ (AUTHOR), Pearce, Robert A⁶ (AUTHOR), Yu, John Paul J⁷ (AUTHOR), Li, Lingjun⁵ (AUTHOR), Denu, John M⁴ (AUTHOR), Puglielli, Luigi^1,2,8 (AUTHOR) lp1@medicine.wisc.edu

Source: Brain: A Journal of Neurology. Feb2022, Vol. 145 Issue 2, p500-516. 17p.

Subject Terms: *DENDRITIC spines, *AUTISM spectrum disorders, *MORPHOLOGY, *NEURONS, *WHITE matter (Nerve tissue), *ACETYLCOENZYME A

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Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy?

Authors: Martellucci, Stefano¹ (AUTHOR) stefano.martellucci@uniroma1.it, Orefice, Nicola Salvatore^2,3 (AUTHOR) nicolaorefice819@gmail.com, Angelucci, Adriano¹ (AUTHOR) adriano.angelucci@univaq.it, Luce, Amalia⁴ (AUTHOR) amalia.luce@unicampania.it, Caraglia, Michele^4,5 (AUTHOR) michele.caraglia@unicampania.it, Zappavigna, Silvia⁴ (AUTHOR) silvia.zappavigna@unicampania.it

Source: International Journal of Molecular Sciences. Sep2020, Vol. 21 Issue 18, p6486-6486. 1p.

Subject Terms: *EXTRACELLULAR vesicles, *DRUG resistance in cancer cells, *CANCER diagnosis, *TUMOR markers, *MICRORNA, *SHUTTLE services

Development of New Strategies Using Extracellular Vesicles Loaded with Exogenous Nucleic Acid.

Authors: Orefice, Nicola Salvatore^1,2 (AUTHOR) nicolaorefice819@gmail.com

Source: Pharmaceutics. Aug2020, Vol. 12 Issue 8, p705. 1p.

Subject Terms: *EXTRACELLULAR vesicles, *NUCLEIC acids, *ADENO-associated virus, *NON-coding RNA, *CELL communication, *CATIONIC lipids

Necrotizing skin lesion and radial nerve palsy in a patient treated with glatiramer acetate

Authors: Carotenuto, Antonio, Iodice, Rosa, Barbato, Francesco, Orefice, Nicola Salvatore, Orefice, Giuseppe

Source: In Journal of the Neurological Sciences 15 August 2013 331(1-2):172-173