Human bone tissue-derived ECM hydrogels: Controlling physicochemical, biochemical, and biological properties through processing parameters

Authors: Kim, Yang-Hee, Cidonio, Gianluca, Kanczler, Janos M., Oreffo, Richard OC., Dawson, Jonathan I.

Source: In Bioactive Materials January 2025 43:114-128

The management, treatment and study of skeletal pain harnessing tissue engineering models

Authors: Iafrate, Lucia, Benedetti, Maria Cristina, Donsante, Samantha, Rosa, Alessandro, Corsi, Alessandro, Oreffo, Richard OC, Riminucci, Mara, Ruocco, Giancarlo, Scognamiglio, Chiara, Cidonio, Gianluca

Subject Terms: Physics - Biological Physics

Access URL: http://arxiv.org/abs/2204.13345

A decade of progress: Achievements and future challenges for regenerative medicine research in the United Kingdom

Authors: Curle, Annabel J., Barnes, Josephine L., Owen, Robert, Barker, Roger A., El Haj, Alicia, Forbes, Stuart J., Ghevaert, Cedric, Oreffo, Richard OC., Rose, Felicity RAJ., Stevens, Molly M., Hewitt, Zoe

Source: In Journal of Immunology and Regenerative Medicine August 2024 24-25

Polymersome nanoparticles for delivery of Wnt-activating small molecules

Authors: Scarpa, Edoardo, Janeczek, Agnieszka A, Hailes, Alethia, de Andrés, Maria C, De Grazia, Antonio, Oreffo, Richard OC, Newman, Tracey A, Evans, Nicholas D

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine June 2018 14(4):1267-1277

Regulation of the Bone Vascular Network is Sexually Dimorphic

Authors: Goring, Alice, Sharma, Aikta, Javaheri, Behzad, Smith, Rosanna CG, Kanczler, Janos M, Boyde, Alan, Hesse, Eric, Mahajan, Sumeet, Olsen, Bjorn R, Pitsillides, Andrew A, Schneider, Philipp, Oreffo, Richard OC, Clarkin, Claire E

Source: Journal of bone and mineral research. 34(11):2117-2132

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092790241.0x000001&indx=1&recIds=ETOCvdc_100092790241.0x000001

Regenerative medicine in lower limb reconstruction

Authors: McEwan, Josephine K, Tribe, Howard C, Jacobs, Neal, Hancock, Nicholas, Qureshi, Amir A, Dunlop, Douglas G, Oreffo, Richard OC

Source: Regenerative medicine. 13(4):477-490

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183399207.0x000001&indx=1&recIds=ETOCvdc_100183399207.0x000001

Application of 3D-printed patient-specific skeletal implants augmented with autologous skeletal stem cells

Authors: Goriainov, Vitali, McEwan, Josephine K, Oreffo, Richard OC, Dunlop, Doug G

Source: Regenerative medicine. 13(3):283-294

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175008940.0x000001&indx=1&recIds=ETOCvdc_100175008940.0x000001

Preservation and stability of cell therapy products: recommendations from an expert workshop

Authors: Stacey, Glyn N, Connon, Che J, Coopman, Karen, Dickson, Alan J, Fuller, Barry, Hunt, Charles J, Kemp, Paul, Kerby, Julie, Man, Jennifer, Matejtschuk, Paul, Moore, Harry, Morris, John, Oreffo, Richard OC, Slater, Nigel, Ward, Stephen, Wiggins, Claire, Zimmermann, Heiko

Source: Regenerative medicine. 12(5):553-564

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159249395.0x000001&indx=1&recIds=ETOCvdc_100159249395.0x000001

PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations

Authors: Janeczek, Agnieszka A, Scarpa, Edoardo, Horrocks, Mathew H, Tare, Rahul S, Rowland, Caroline A, Jenner, Dominic, Newman, Tracey A, Oreffo, Richard OC, Lee, Steven F, Evans, Nicholas D

Source: Nanomedicine. 12(8):845-863

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147074300.0x000001&indx=1&recIds=ETOCvdc_100147074300.0x000001

Chapter 16 - Cartilage and bone regeneration

Authors: Lindahl, Anders, Brittberg, Mats, Gibbs, David, Dawson, Jonathan I., Kanczler, Janos, Black, Cameron, Tare, Rahul, Oreffo, Richard OC.

Source: In Tissue Engineering Edition: Third Edition. 2023:533-583

Single-cell RNA-sequence analysis of human bone marrow reveals new targets for isolation of skeletal stem cells using spherical nucleic acids.

Authors: Matthews, Elloise Z, Lanham, Stuart, White, Kate, Kyriazi, Maria-Eleni, Alexaki, Konstantina, El-Sagheer, Afaf H, Brown, Tom, Kanaras, Antonios G, J West, Jonathan, MacArthur, Ben D, Stumpf, Patrick S, Oreffo, Richard OC

Source: Journal of Tissue Engineering; 5/16/2023, p1-21, 21p

Subject Terms: BONE marrow, STEM cells, BONE growth, CLINICAL medicine, RNA sequencing

Contributors

Authors: Aldana, Ana A., Alexander, Morgan R., Atala, Anthony, Badylak, Stephen F., Baker, Matthew B., Bauer, Jurica, Black, Cameron, Bobbala, Sharan, Brittberg, Mats, Brook, Gary A., Buchanan, Fraser, Carlier, Aurélie, Chen, Saray, Claes, Evan, Cohen, Smadar, Connelly, John, Dalby, Matthew J., Dalton, Paul D., Dawson, Jonathan I., de Boer, Jan, Desmet, Tim, Donnelly, Hannah, Donvil, Filip, Dziki, Jenna L., Egger, Dominik, Filippi, Miriam, Gensler, Marius, Gibbs, David, Gibbs, Susan, Hannen, Rosalind, Hansmann, Jan, Harvey, Alan R., Heck, Tommy, Herrmann, Marietta, Hook, Andrew L., Hubbell, Jeffrey A., Hutmacher, Dietmar W., Hynes, Clara Grace, Joly, Johan, Jorgensen, Adam M., Kanczler, Janos, Karperien, Marcel, Kasper, Cornelia, Kerr, Candace L., Kilian, Kristopher A., Kreß, Sebastian, LaPointe, Vanessa, Laschke, Matthias W., Lindahl, Anders, Londono, Ricardo, Luyten, Frank P., Marechal, Marina, Martino, Mikaël M., Moos, Malcolm, Jr., Moroni, Lorenzo, Morra, Emily, Myers, Simon, Nebel, Sabrina, Nie, Minghao, Nisbet, David R., O'Neill, Kelly L., Ojeh, Nkemcho, Oreffo, Richard OC., Oudega, Martin, Passier, Robert, Pêgo, Ana Paula, Pittenger, Mark F., Plant, Giles W., Rice, Jeffrey J., Roelen, Bernard A.J., Schaschkow, Anaïs, Scherberich, Arnaud, Schrooten, Jan, Scott, Evan A., Sicari, Brian M., Sonnaert, Maarten, Später, Thomas, Takeuchi, Shoji, Tandon, Biranche, Tare, Rahul, Truckenmüller, Roman, Tsimbouri, Monica, Uquillas, Jorge Alfredo, Van Assche, Dieter, Vermeulen, Steven, Verrier, Sophie, Walsh, Pamela, Winkler, David A.

Source: In Tissue Engineering Edition: Third Edition. 2023:xv-xix

Evolving applications of the egg: chorioallantoic membrane assay and ex vivo organotypic culture of materials for bone tissue engineering.

Authors: Marshall, Karen M, Kanczler, Janos M, Oreffo, Richard OC

Source: Journal of Tissue Engineering; 10/20/2020, p1-25, 25p

Subject Terms: CHORIOALLANTOIS, TISSUE engineering, BONES, MATERIAL culture, DENTAL research, BONE growth, BONE regeneration

Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol.

Authors: de Andrés, María C, Meiss, Mia S, Sánchez-Hidalgo, Marina, González-Benjumea, Alejandro, Fernández-Bolaños, Jose G, Alarcón-de-la-Lastra, Catalina, Oreffo, Richard OC

Source: Journal of Tissue Engineering; 5/27/2020, Vol. 11, p1-13, 13p

Subject Terms: OLIVE oil, OSTEOARTHRITIS, OXIDATIVE stress, NITRIC oxide, CARTILAGE, POLYPHENOLS

Chondrogenic potential of human articular chondrocytes and skeletal stem cells: A comparative study.

Authors: Li, Siwei, Sengers, Bram G, Oreffo, Richard OC, Tare, Rahul S

Source: Journal of Biomaterials Applications; Jan2015, Vol. 29 Issue 6, p824-836, 13p

Subject Terms: COMPARATIVE studies, CHONDROGENESIS, CARTILAGE cells, STEM cells, REGENERATIVE medicine, CELL differentiation, LIFE spans

Centre for Human Development, Stem Cells & Regeneration.

Authors: Oreffo, Richard OC

Source: Regenerative Medicine; Sep2014, Vol. 9 Issue 5, p563-567, 5p

Hope versus hype: what can additive manufacturing realistically offer trauma and orthopedic surgery?

Authors: Gibbs, David MR, Vaezi, Mohammad, Yang, Shoufeng, Oreffo, Richard OC

Source: Regenerative Medicine; Jul2014, Vol. 9 Issue 4, p535-549, 15p

Induction of Human Osteoprogenitor Chemotaxis, Proliferation, Differentiation, and Bone Formation by Osteoblast Stimulating Factor-1/Pleiotrophin: Osteoconductive Biomimetic Scaffolds for Tissue Engineering.

Authors: Yang, Xuebin, Tare, Rahul S, Partridge, Kris A, Roach, Helmtrud I, Clarke, Nicholas MP, Howdle, Steven M, Shakesheff, Kevin M, Oreffo, Richard OC

Source: Journal of Bone & Mineral Research; Jan2003, Vol. 18 Issue 1, p47-57, 11p

Biological and mechanical enhancement of impacted allograft seeded with human bone marrow stromal cells: potential clinical role in impaction bone grafting

Authors: Bolland, Benjamin JRF, Partridge, Kris, Tilley, Simon, New, Andrew MR, Dunlop, Douglas G, Oreffo, Richard OC

Source: Regenerative Medicine; July 2006, Vol. 1 Issue: 4 p457-467, 11p

The chorioallantoic membrane (CAM) assay for the study of human bone regeneration: a refinement animal model for tissue engineering.

Authors: Moreno-Jiménez, Inés, Hulsart-Billstrom, Gry, Lanham, Stuart A., Janeczek, Agnieszka A., Kontouli, Nasia, Kanczler, Janos M., Evans, Nicholas D., Oreffo, Richard OC

Source: Scientific Reports; 9/2/2016, p32168, 1p