Clinicopathological Predictors of the Presence of Blood Circulating Tumor DNA in Early-Stage Non–Small Cell Lung Cancers

Authors: Driussi, Arnaud ^a, Lamaze, Fabien C. ^a, Kordahi, Manal ^a, Armero, Victoria Saavedra ^a, Gaudreault, Nathalie ^a, Orain, Michèle ^a, Enlow, William ^a, Abbosh, Chris ^b, Hodgson, Darren ^b, Dasgupta, Abhijit ^c, Gagné, Andréanne ^a, Bossé, Yohan ^{a, d}, Joubert, Philippe ^{a, e, ∗}

Source: In Modern Pathology June 2025 38(6)

Prognostic implication of methylation-based circulating tumor DNA detection prior to surgery in stage I non-small cell lung cancer

Authors: Bossé, Yohan, Dasgupta, Abhijit, Abadier, Michael, Guthrie, Violeta, Song, Florian, Saavedra Armero, Victoria, Gaudreault, Nathalie, Orain, Michèle, Lamaze, Fabien C., Melton, Collin, Nance, Tracy, Hung, Tiffany, Hodgson, Darren, Abbosh, Chris, Joubert, Philippe

Source: In Cancer Letters 10 July 2024 594

Imaging-Based Biomarkers Predict Programmed Death-Ligand 1 and Survival Outcomes in Advanced NSCLC Treated With Nivolumab and Pembrolizumab: A Multi-Institutional Study

Authors: Yolchuyeva, Sevinj, Giacomazzi, Elena, Tonneau, Marion, Lamaze, Fabien, Orain, Michele, Coulombe, François, Malo, Julie, Belkaid, Wiam, Routy, Bertrand, Joubert, Philippe, Manem, Venkata S.K.

Source: In JTO Clinical and Research Reports December 2023 4(12)

A Simplified Version of the IASLC Grading System for Invasive Pulmonary Adenocarcinomas With Improved Prognosis Discrimination

Authors: Bossé, Yohan, Gagné, Andréanne, Althakfi, Wajd A., Orain, Michèle, Couture, Christian, Trahan, Sylvain, Pagé, Sylvain, Joubert, David, Fiset, Pierre O., Desmeules, Patrice, Joubert, Philippe

Source: American journal of surgical pathology. 47(6):686-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191123985.0x000001&indx=1&recIds=ETOCvdc_100191123985.0x000001

Prognostic value of complex glandular patterns in invasive pulmonary adenocarcinomas

Authors: Bossé, Yohan, Gagné, Andréanne, Althakfi, Wajd, Orain, Michèle, Fiset, Pierre Olivier, Desmeules, Patrice, Joubert, Philippe

Source: In Human Pathology October 2022 128:56-68

Impact of Implementing a Grossing Tumor-margin Distance Threshold for Frozen Section in Oncologic Lung Surgery.

Authors: Kordahi, Manal, Gagné, Andréanne, Abolfathi, Hanie, Orain, Michèle, Couture, Christian, Desmeules, Patrice, Trahan, Sylvain, Pagé, Sylvain, Vaucher, Jonathan, Nicodème, Frederic, Conti, Massimo, Ugalde Figueroa, Paula, Laliberté, Anne-Sophie, Lamaze, Fabien C., Bossé, Yohan, Joubert, Philippe

Source: American Journal of Surgical Pathology; Feb2025, Vol. 49 Issue 2, p169-175, 7p

Venous thrombotic events in patients treated with immune checkpoint inhibitors for non-small cell lung cancer: A retrospective multicentric cohort study

Authors: Deschênes-Simard, Xavier, Richard, Corentin, Galland, Loïck, Blais, Florence, Desilets, Antoine, Malo, Julie, Cvetkovic, Lena, Belkaid, Wiam, Elkrief, Arielle, Gagné, Andréanne, Hamel, Marc-André, Orain, Michèle, Joubert, Philippe, Ghiringhelli, François, Routy, Bertrand, Blais, Normand

Source: In Thrombosis Research September 2021 205:29-39

Sensitivity of CT-derived radiomic features to extraction libraries and gray-level discretization in the context of immune biomarker discovery.

Authors: Ebrahimpour, Leyla, Lemaréchal, Yannick, Yolchuyeva, Sevinj, Orain, Michèle, Lamaze, Fabien, Driussi, Arnaud, Coulombe, François, Joubert, Philippe, Després, Philippe, Manem, Venkata S K

Source: British Journal of Radiology; Dec2024, Vol. 97 Issue 1164, p1982-1991, 10p

Subject Terms: NON-small-cell lung carcinoma, TUMOR-infiltrating immune cells, IMMUNE checkpoint inhibitors, FEATURE extraction, RADIOMICS

Phospho-histone-H3 immunostaining for pulmonary carcinoids: impact on clinical appraisal, interobserver correlation, and diagnostic processing efficiency

Authors: Laflamme, Philippe, Mansoori, Babak K., Sazanova, Olga, Orain, Michèle, Couture, Christian, Simard, Serge, Trahan, Sylvain, Manem, Venkata, Joubert, Philippe

Source: In Human Pathology December 2020 106:74-81

Development and Validation of Diffuse Idiopathic Pulmonary Neuroendocrine Hyperplasia Diagnostic Criteria

Authors: Sazonova, Olga, Manem, Venkata, Béland, Chloé, Hamel, Marc-André, Lacasse, Yves, Lévesque, Marie-Hélène, Orain, Michèle, Joubert, David, Provencher, Steeve, Simonyan, David, Joubert, Philippe

Source: In JTO Clinical and Research Reports November 2020 1(4)

Transcriptomic data helps refining classification of pulmonary carcinoid tumors with increased mitotic counts

Authors: Sazonova, Olga, Manem, Venkata, Orain, Michèle, Khoshkrood-Mansoori, Babak, Gaudreault, Nathalie, Desmeules, Patrice, Bossé, Yohan, Joubert, Philippe

Source: In Modern Pathology September 2020 33(9):1712-1721

Comprehensive assessment of PD-L1 immunohistochemistry on paired tissue and cytology specimens from non-small cell lung cancer

Authors: Gagné, Andréanne, Orain, Michèle, Ionescu, Diana, Tsao, Ming-Sound, Joubert, David, Joubert, Philippe ^*

Source: In Lung Cancer August 2020 146:276-284

Efficacy of immune checkpoint inhibitors in older patients with non-small cell lung cancer: Real-world data from multicentric cohorts in Canada and France

Authors: Elkrief, Arielle, Richard, Corentin, Malo, Julie, Cvetkovic, Lena, Florescu, Marie, Blais, Normand, Tehfe, Mustapha, Messaoudene, Meriem, Gagné, Andréanne, Orain, Michele, Medjebar, Soleine, Wan-Chow-Wah, Doreen, Joubert, Philippe, Labbé, Catherine, Ghiringhelli, Francois, Routy, Bertrand

Source: In Journal of Geriatric Oncology June 2020 11(5):802-806

Impact of Specimen Characteristics on PD-L1 Testing in Non–Small Cell Lung Cancer: Validation of the IASLC PD-L1 Testing Recommendations

Authors: Gagné, Andréanne, Wang, Emily, Bastien, Nathalie, Orain, Michèle, Desmeules, Patrice, Pagé, Sylvain, Trahan, Sylvain, Couture, Christian, Joubert, David, Joubert, Philippe

Source: In Journal of Thoracic Oncology December 2019 14(12):2062-2070

Coronary artery fixation at iso-arterial pressure: impacts on histologic evaluation and clinical management

Authors: Laflamme, Philippe, Vaucher, Jonathan, Turmel-Roy, Justine, Orain, Michèle, Sazonova, Olga, Bertrand, Olivier F., Dagenais, François, Couture, Christian, Pagé, Sylvain, Trahan, Sylvain, Bilodeau, Sylvie, Joubert, Philippe

Source: In Cardiovascular Pathology November-December 2019 43

Metabolomic Profiling of Pulmonary Neuroendocrine Neoplasms.

Authors: Boullier, Clémence, Lamaze, Fabien C., Haince, Jean-François, Bux, Rashid Ahmed, Orain, Michèle, Zheng, Jiamin, Zhang, Lun, Wishart, David S., Bossé, Yohan, Manem, Venkata S. K., Joubert, Philippe

Source: Cancers; Sep2024, Vol. 16 Issue 18, p3179, 18p

Subject Terms: MEDICAL logic, LIQUID chromatography-mass spectrometry, T-test (Statistics), BODY mass index, DATA analysis, RESEARCH funding, EARLY detection of cancer, SAMPLE size (Statistics), TUMOR markers, CANCER patients, DESCRIPTIVE statistics, CHI-squared test, MANN Whitney U Test, CELL lines, LUNG tumors, NEUROENDOCRINE tumors, CASE-control method, STATISTICS, METABOLOMICS, COMPARATIVE studies, DATA analysis software, CONFIDENCE intervals, REGRESSION analysis

Widespread and Functional RNA Circularization in Localized Prostate Cancer

Authors: Chen, Sujun, Huang, Vincent, Xu, Xin, Livingstone, Julie, Soares, Fraser, Jeon, Jouhyun, Zeng, Yong, Hua, Junjie Tony, Petricca, Jessica, Guo, Haiyang, Wang, Miranda, Yousif, Fouad, Zhang, Yuzhe, Donmez, Nilgun, Ahmed, Musaddeque, Volik, Stas, Lapuk, Anna, Chua, Melvin L.K., Heisler, Lawrence E., Foucal, Adrien, Fox, Natalie S., Fraser, Michael, Bhandari, Vinayak, Shiah, Yu-Jia, Guan, Jiansheng, Li, Jixi, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Fradet, Yves, Têtu, Bernard, Liu, Stanley, Feng, Felix, Wu, Xue, Shao, Yang W., Komor, Malgorzata A., Sahinalp, Cenk, Collins, Colin, Hoogstrate, Youri, de Jong, Mark, Fijneman, Remond J.A., Fei, Teng, Jenster, Guido, van der Kwast, Theodorus, Bristow, Robert G., Boutros, Paul C., He, Housheng Hansen

Source: In Cell 7 February 2019 176(4):831-843

Association between physical activity and the expression of mediators of inflammation in normal breast tissue among premenopausal and postmenopausal women

Authors: Hanna, Mirette, Dumas, Isabelle, Orain, Michèle, Jacob, Simon, Têtu, Bernard, Diorio, Caroline

Source: In Cytokine February 2018 102:151-160

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

Authors: Houlahan, Kathleen, Shiah, Yu-Jia, Gusev, Alexander, Yuan, Jiapei, Ahmed, Musaddeque, Shetty, Anamay, Ramanand, Susmita, Yao, Cindy, Bell, Connor, O'Connor, Edward, Huang, Vincent, Fraser, Michael, Heisler, Lawrence, Livingstone, Julie, Yamaguchi, Takafumi, Rouette, Alexandre, Foucal, Adrien, Espiritu, Shadrielle, Sinha, Ankit, Sam, Michelle, Timms, Lee, Johns, Jeremy, Wong, Ada, Murison, Alex, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Lupien, Mathieu, Fradet, Yves, Têtu, Bernard, McPherson, John, Pasaniuc, Bogdan, Kislinger, Thomas, Chua, Melvin, Pomerantz, Mark, Kwast, Theodorus, Freedman, Matthew, Mani, Ram, He, Housheng, Bristow, Robert, Boutros, Paul

Source: Nature medicine. 25(10):1615-1626

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190842634.0x000001&indx=1&recIds=ETOCvdc_100190842634.0x000001

A Prostate Cancer “Nimbosus”: Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies

Authors: Chua, Melvin L.K., Lo, Winnie, Pintilie, Melania, Murgic, Jure, Lalonde, Emilie, Bhandari, Vinayak, Mahamud, Osman, Gopalan, Anuradha, Kweldam, Charlotte F., van Leenders, Geert J.L.H., Verhoef, Esther I., Hoogland, Agnes Marije, Livingstone, Julie, Berlin, Alejandro, Dal Pra, Alan, Meng, Alice, Zhang, Junyan, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Fradet, Yves, Têtu, Bernard, Reuter, Victor E., Fleshner, Neil, Fraser, Michael, Boutros, Paul C., van der Kwast, Theodorus H., Bristow, Robert G.

Source: In European Urology November 2017 72(5):665-674