A hydride transfer complex reprograms NAD metabolism and bypasses senescence

Authors: Igelmann, Sebastian, Lessard, Frédéric, Uchenunu, Oro, Bouchard, Jacob, Fernandez-Ruiz, Ana, Rowell, Marie-Camille, Lopes-Paciencia, Stéphane, Papadopoli, David, Fouillen, Aurélien, Ponce, Katia Julissa, Huot, Geneviève, Mignacca, Lian, Benfdil, Mehdi, Kalegari, Paloma, Wahba, Haytham M., Pencik, Jan, Vuong, Nhung, Quenneville, Jordan, Guillon, Jordan, Bourdeau, Véronique, Hulea, Laura, Gagnon, Etienne, Kenner, Lukas, Moriggl, Richard, Nanci, Antonio, Pollak, Michael N., Omichinski, James G., Topisirovic, Ivan, Ferbeyre, Gerardo

Source: In Molecular Cell 16 September 2021 81(18):3848-3865

Role of active site arginine residues in substrate recognition by PPM1A

Authors: Tani, Itsumi, Ito, Shogo, Shirahata, Yukiko, Matsuyama, Yutaka, Omichinski, James G., Shimohigashi, Yasuyuki, Kamada, Rui, Sakaguchi, Kazuyasu

Source: Biochemical and biophysical research communications. 581:1-5

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100149311737.0x000001&indx=1&recIds=ETOCvdc_100149311737.0x000001

MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells

Authors: Bottardi, Stefania, Guieze, Romain, Bourgoin, Vincent, Fotouhi-Ardakani, Nasser, Dougé, Aurore, Darracq, Anaïs, Lakehal, Yahia A., Berger, Marc G., Mollica, Luigina, Bay, Jacques-Olivier, Omichinski, James G., Milot, Eric

Source: In Experimental Hematology August 2020 88:68-82

Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins

Authors: Lussier-Price, Mathieu, Mascle, Xavier H., Cappadocia, Laurent, Kamada, Rui, Sakaguchi, Kazuyasu, Wahba, Haytham M., Omichinski, James G.

Source: In Structure 5 May 2020 28(5):573-585

Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner

Authors: Mascle, Xavier H., Gagnon, Christina, Wahba, Haytham M., Lussier-Price, Mathieu, Cappadocia, Laurent, Sakaguchi, Kazuyasu, Omichinski, James G.

Source: In Structure 4 February 2020 28(2):157-168

The tetramerization domain of the tree shrew p53 protein displays unique thermostability despite sharing high sequence identity with the human p53 protein

Authors: Nakagawa, Natsumi, Sakaguchi, Shuya, Nomura, Takao, Kamada, Rui, Omichinski, James G., Sakaguchi, Kazuyasu

Source: Biochemical and biophysical research communications. 521(3):681-686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094843120.0x000001&indx=1&recIds=ETOCvdc_100094843120.0x000001

Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR.

Authors: Ali, Mohamed G., Wahba, Haytham M., Igelmann, Sebastian, Cyr, Normand, Ferbeyre, Gerardo, Omichinski, James G.

Source: Autophagy; Sep2024, Vol. 20 Issue 9, p1948-1967, 20p

Subject Terms: PROTEIN receptors, ACETYLATION, TUMOR proteins, ISOTHERMAL titration calorimetry, NUCLEAR proteins

NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA Polymerase II Carboxyl-Terminal Domain Phosphatase FCP1

Authors: Nguyen, Bao D., Abbott, Karen L., Potempa, Krzysztof, Kobor, Michael S., Archambault, Jacques, Greenblatt, Jack, Legault, Pascale, Omichinski, James G.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 May . 100(10), 5688-5693.

Access URL: https://www.jstor.org/stable/3147478

Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch

Authors: Desrochers, Guillaume, Cappadocia, Laurent, Lussier-Price, Mathieu, Ton, Anh-Tien, Ayoubi, Riham, Serohijos, Adrian, Omichinski, James G., Angers, Annie

Source: In Journal of Biological Chemistry 14 April 2017 292(15):6325-6338

The Single Cys2-His2 Zinc Finger Domain of the GAGA Protein Flanked by Basic Residues is Sufficient for High-Affinity Specific DNA Binding

Authors: Pedone, Paolo V., Ghirlando, Rodolfo, Clore, G. Marius, Gronenborn, Angela M., Felsenfeld, Gary, Omichinski, James G.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1996 Apr 01. 93(7), 2822-2826.

Access URL: https://www.jstor.org/stable/39071

The Wing of the Enhancer-Binding Domain of Mu Phage Transposase is Flexible and is Essential for Efficient Transposition

Authors: Clubb, Robert T., Mizuuchi, Michiyo, Huth, Jeffrey R., Omichinski, James G., Savilahti, Harri, Mizuuchi, Kiyoshi, Clore, G. Marius, Gronenborn, Angela M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1996 Feb 01. 93(3), 1146-1150.

Access URL: https://www.jstor.org/stable/38763

A ΩX a V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

Authors: Cyr, Normand, de la Fuente, Cynthia, Lecoq, Lauriane, Guendel, Irene, Chabot, Philippe R., Kehn-Hall, Kylene, Omichinski, James G.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 May 01. 112(19), 6021-6026.

Access URL: https://www.jstor.org/stable/26462734

Monomer‐to‐dimer transition of Brucella suis type IV secretion system component VirB8 induces conformational changes

Authors: Sharifahmadian, Mahzad, Arya, Tarun, Bessette, Benoit, Lecoq, Lauriane, Ruediger, Edward, Omichinski, James G., Baron, Christian

Source: FEBS journal. 284(8):1218-1232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083710379.0x000001&indx=1&recIds=ETOCvdc_100083710379.0x000001

Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon—Metal Bond Cleavage

Authors: Wahba, Haytham M., Stevenson, Michael J., Mansour, Ahmed, Sygusch, Jurgen, Wilcox, Dean E., Omichinski, James G.

Source: Journal of the American Chemical Society. 139(2):910-921

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN609746887&indx=1&recIds=ETOCRN609746887

Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1

Authors: Cappadocia, Laurent, Mascle, Xavier H., Bourdeau, Véronique, Tremblay-Belzile, Samuel, Chaker-Margot, Malik, Lussier-Price, Mathieu, Wada, Junya, Sakaguchi, Kazuyasu, Aubry, Muriel, Ferbeyre, Gerardo, Omichinski, James G.

Source: In Structure 6 January 2015 23(1):126-138

Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg—Carbon Bond Cleavage and Metal Binding Specificity

Authors: Wahba, Haytham M., Lecoq, Lauriane, Stevenson, Michael, Mansour, Ahmed, Cappadocia, Laurent, Lafrance-Vanasse, Julien, Wilkinson, Kevin J., Sygusch, Jurgen, Wilcox, Dean E., Omichinski, James G.

Source: Biochemistry. 55(7):1070-1081

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605190284&indx=1&recIds=ETOCRN605190284

Biomineralization through a Symmetry-Controlled Oligomeric Peptide.

Authors: Sakaguchi, Tatsuya, Nakagawa, Natsumi, Mine, Kenta, Janairo, Jose Isagani B., Kamada, Rui, Omichinski, James G., Sakaguchi, Kazuyasu

Source: Biomimetics (2313-7673); Dec2023, Vol. 8 Issue 8, p606, 12p

Subject Terms: PEPTIDES, BIOMINERALIZATION, SPATIAL arrangement, VALENCE (Chemistry)

Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.

Authors: Sakaguchi, Shuya, Nakagawa, Natsumi, Wahba, Haytham M., Wada, Junya, Kamada, Rui, Omichinski, James G., Sakaguchi, Kazuyasu

Source: International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 23, p16620, 18p

Subject Terms: P53 protein, SPECIES, TUMOR suppressor proteins, SHREWS, GUINEA pigs, OPOSSUMS

Identification of a Non-covalent Ternary Complex Formed by PIAS1, SUMO1, and UBC9 Proteins Involved in Transcriptional Regulation

Authors: Mascle, Xavier H., Lussier-Price, Mathieu, Cappadocia, Laurent, Estephan, Patricia, Raiola, Luca, Omichinski, James G., Aubry, Muriel

Source: In Journal of Biological Chemistry 20 December 2013 288(51):36312-36327

Structural Characterization of a Noncovalent Complex between Ubiquitin and the Transactivation Domain of the Erythroid-Specific Factor EKLF

Authors: Raiola, Luca, Lussier-Price, Mathieu, Gagnon, David, Lafrance-Vanasse, Julien, Mascle, Xavier, Arseneault, Genevieve, Legault, Pascale, Archambault, Jacques, Omichinski, James G.

Source: In Structure 5 November 2013 21(11):2014-2024