Mimicry-based strategy between human and commensal antigens for the development of a new family of immune therapies for cancer

Authors: Agostina Stradella, Francois Ghiringhelli, Ana Maia, Cécile Gouttefangeas, Ulrich Herrlinger, Maria Vieito, Ahmed Idbaih, Ghazaleh Tabatabai, Olivier Adotevi, Alice Talpin, Jennifer Martinez, Wolfgang Wick, Laura Boullerot, Jerome Kervevan, Lucie Aubergeon, Diana Bachrouche, Chloé Ventujol, Léa Bernard, Amandine Manteau, Christophe Bonny, Laurent Chene, Iris Mildenberger, Michael C Burger, Jean-Marie Carpier, Guillaume Kulakowski, Camille Gaal, Francesco Strozzi, Coline Billerey, Ludivine Amable, Tifanny Mersceman, Alexandrine Garnier, Càtia Oliveira, Carolina Calderon, Michaël Bonnet, Julie Noguerol, Karl Laviolette, Marine Malfroy, Gregoire Chevalier, Olivier Joffre, David A. Reardon, Joao Gamelas Magalhaes

Source: Journal for ImmunoTherapy of Cancer, Vol 13, Iss 2 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/13/2/e010192.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/4ff1b5a31908438593b4df2f4455eb45

New leads to enhance tagraxofusp efficacy in pDC-AML

Authors: Morgane Boichut, Margaux Poussard, Xavier Roussel, Imane Belakri, Sabeha Biichlé, Maxime Fredon, Florian Renosi, Romain Boidot, Olivier Adotevi, Christopher Brooks, Francine Garnache-Ottou, Fanny Angelot Delettre

Source: Blood Neoplasia, Vol 2, Iss 2, Pp 100066- (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950328025000019; https://doaj.org/toc/2950-3280

Access URL: https://doaj.org/article/aed201e929a94e21a41b1d9ad6307c36

Durable response of lung carcinoma patients to EGFR tyrosine kinase inhibitors is determined by germline polymorphisms in some immune-related genes

Authors: Lorraine Dalens, Julie Niogret, Corentin Richard, Sandy Chevrier, Pascal Foucher, Bruno Coudert, Aurélie Lagrange, Laure Favier, Virginie Westeel, Stefano Kim, Olivier Adotevi, Caroline Chapusot, Laurent Martin, Laurent Arnould, Courèche-Guillaume Kaderbhai, Romain Boidot

Source: Molecular Cancer, Vol 22, Iss 1, Pp 1-9 (2023)

Subject Terms: Lung carcinoma, Exome analysis, SNPs, Innate immunity, EGFR TKI, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/fae01f6d6f6245acad2b87dbc4464121

Evaluation of the interest to combine a CD4 Th1-inducer cancer vaccine derived from telomerase and atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma: a randomized non-comparative phase II study (TERTIO – PRODIGE 82)

Authors: Angélique Vienot, Marion Jacquin, Magali Rebucci-Peixoto, Dimitri Pureur, François Ghiringhelli, Eric Assenat, Pascal Hammel, Olivier Rosmorduc, Morgane Stouvenot, Manon Allaire, Mohamed Bouattour, Hélène Regnault, Serge Fratte, Eric Raymond, Emilie Soularue, Stéphanie Husson-Wetzel, Vincent Di Martino, Allison Muller, Anne-Laure Clairet, Christine Fagnoni-Legat, Olivier Adotevi, Aurélia Meurisse, Dewi Vernerey, Christophe Borg

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)

Subject Terms: Hepatocellular carcinoma, Immunotherapy, Vaccination, Telomerase, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/39a0fdecdfae4b14bb524649b02db940

THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1

Authors: Julie Giraud, Domitille Chalopin, Eloïse Ramel, Thomas Boyer, Atika Zouine, Marie-Alix Derieppe, Nicolas Larmonier, Olivier Adotevi, Brigitte Le Bail, Jean-Frédéric Blanc, Christophe Laurent, Laurence Chiche, Marc Derive, Macha Nikolski, Maya Saleh

Source: Cell Reports, Vol 43, Iss 2, Pp 113773- (2024)

Subject Terms: CP: Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724001013; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/023f817342b74e968922605adf63aef4

Predictive biomarkers and specific immune responses of COVID-19 mRNA vaccine in patients with cancer: prospective results from the CACOV-VAC trial

Authors: Laura Mansi, Olivier Adotevi, Marie Kroemer, Laurie Spehner, Adeline Bouard, Marine Jary, Romain Loyon, Christophe Borg, Dewi Vernerey, Syrine Abdeljaoued, Myriam Ben Khelil, Quentin Lepiller, Emeline Orillard, Antoine Falcoz, Hamadi Almotlak, Stefano Kim, Elsa Curtit, Guillaume Meynard, Charlee Nardin, Kamal Asgarov, Ugo Chartral, Virginie Mougey, Morgane Lopez

Source: BMJ Oncology, Vol 2, Iss 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://bmjoncology.bmj.com/content/2/1/e000054.full; https://doaj.org/toc/2752-7948

Access URL: https://doaj.org/article/663b163dc2b0462e8a3aaeff70cda4cf

Prognostic value of CD4+ T lymphopenia in non-small cell lung Cancer

Authors: Guillaume Eberst, Dewi Vernerey, Caroline Laheurte, Aurélia Meurisse, Vincent Kaulek, Laurie Cuche, Pascale Jacoulet, Hamadi Almotlak, Jean Lahourcade, Marie Gainet-Brun, Elizabeth Fabre, Françoise Le Pimpec-Barthes, Olivier Adotevi, Virginie Westeel

Source: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: CD4+ T lymphopenia, Non small cell lung cancer, Prognosis, CD8+ T lymphopenia - local/loco-regional NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/346b09f08c3e400eaefd24234a603f8a

Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies

Authors: Florent Malard, Béatrice Gaugler, Joel Gozlan, Lucie Bouquet, Djeneba Fofana, Lama Siblany, Deborah Eshagh, Olivier Adotevi, Caroline Laheurte, Laure Ricard, Rémy Dulery, Nicolas Stocker, Zoe van de Wyngaert, Alexis Genthon, Anne Banet, Mara Memoli, Souhila Ikhlef, Simona Sestilli, Anne Vekhof, Eolia Brissot, Zora Marjanovic, Yannick Chantran, Nancy Cuervo, Eric Ballot, Laurence Morand-Joubert, Mohamad Mohty

Source: Blood Cancer Journal, Vol 11, Iss 8, Pp 1-8 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/8d0058476b484f6287eb9b7721046793

A Phase II Study Evaluating the Interest to Combine UCPVax, a Telomerase CD4 TH1-Inducer Cancer Vaccine, and Atezolizumab for the Treatment of HPV Positive Cancers: VolATIL Study

Authors: Magali Rebucci-Peixoto, Angélique Vienot, Olivier Adotevi, Marion Jacquin, Francois Ghiringhelli, Christelle de la Fouchardière, Benoit You, Tristan Maurina, Elsa Kalbacher, Fernando Bazan, Guillaume Meynard, Anne-Laure Clairet, Christine Fagnoni-Legat, Laurie Spehner, Adeline Bouard, Dewi Vernerey, Aurélia Meurisse, Stefano Kim, Christophe Borg, Laura Mansi

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: HPV-related cancer, anal carcinoma, head and neck, cervix, atezolizumab, immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.957580/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/90ac113021e14bb9a976565c61b79c86

TIE-2 Signaling Activation by Angiopoietin 2 On Myeloid-Derived Suppressor Cells Promotes Melanoma-Specific T-cell Inhibition

Authors: Amélie Marguier, Caroline Laheurte, Benoît Lecoester, Marine Malfroy, Laura Boullerot, Adeline Renaudin, Evan Seffar, Abhishek Kumar, Charlée Nardin, François Aubin, Olivier Adotevi

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: ANGPT2, tumor antigen, melanoma, tie-2, M-MDSCs, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.932298/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4ad89da152d74e058957e595e319c057

Human Monocyte-Derived Suppressor Cell Supernatant Induces Immunoregulatory Effects and Mitigates xenoGvHD

Authors: Claire Gérard, Marine Thébault, Baptiste Lamarthée, Coraline Genet, Florine Cattin, Andréa Brazdova, Nona Janikashvili, Claudie Cladière, Marion Ciudad, Séthi Ouandji, Thibault Ghesquière, Hélène Greigert, Claire Tinel, Olivier Adotevi, Philippe Saas, Maxime Samson, Sylvain Audia, Bernard Bonnotte

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: myeloid-derived suppressor cell, xeno GVHD, supernatant characteristics, GMP-good manufacturing practice, immunoregualtion, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.827712/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d0bce2cc24f54a32bbc91216ac963b01

346 Translational program of the phase II MEDITREME trial: identification of prognostic factors for response to durvalumab and tremelimumab in combination with FOLFOX in metastatic colorectal cancer

Authors: Francois Ghiringhelli, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Olivier Adotevi, Caroline Laheurte, Elise Ballot, Jean-David Fumet

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/164fafc8d5f6412aa6f6148372328260

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

Authors: Francine Garnache-Ottou, Chrystelle Vidal, Sabeha Biichlé, Florian Renosi, Eve Poret, Maïder Pagadoy, Maxime Desmarets, Anne Roggy, Estelle Seilles, Lou Soret, Françoise Schillinger, Sandrine Puyraimond, Tony Petrella, Claude Preudhomme, Christophe Roumier, Elisabeth A. MacIntyre, Véronique Harrivel, Yohan Desbrosses, Bérengère Gruson, Franck Geneviève, Sylvain Thepot, Yuriy Drebit, Thibaut Leguay, François-Xavier Gros, Nicolas Lechevalier, Pascale Saussoy, Véronique Salaun, Edouard Cornet, Zehaira Benseddik, Richard Veyrat-Masson, Orianne Wagner-Ballon, Célia Salanoubat, Marc Maynadié, Julien Guy, Denis Caillot, Marie-Christine Jacob, Jean-Yves Cahn, Rémy Gressin, Johann Rose, Bruno Quesnel, Estelle Guerin, Franck Trimoreau, Jean Feuillard, Marie-Pierre Gourin, Adriana Plesa, Lucile Baseggio, Isabelle Arnoux, Norbert Vey, Didier Blaise, Romaric Lacroix, Christine Arnoulet, Blandine Benet, Véronique Dorvaux, Caroline Bret, Bernard Drenou, Agathe Debliquis, Véronique Latger-Cannard, Caroline Bonmati, Marie-Christine Bene, Pierre Peterlin, Michel Ticchioni, Pierre-Simon Rohrlich, Anne Arnaud, Stefan Wickenhauser, Valérie Bardet, Sabine Brechignac, Benjamin Papoular, Victoria Raggueneau, Jacques Vargaftig, Rémi Letestu, Daniel Lusina, Thorsten Braun, Vincent Foissaud, Jérôme Tamburini, Hind Bennani, Nicolas Freynet, Catherine Cordonnier, Magali Le Garff-Tavernier, Nathalie Jacques, Karim Maloum, Damien Roos-Weil, Didier Bouscary, Vahid Asnafi, Ludovic Lhermitte, Felipe Suarez, Etienne Lengline, Frédéric Féger, Giorgia Battipaglia, Mohamad Mohty, Sabrina Bouyer, Ouda Ghoual, Elodie Dindinaud, Caroline Basle, Mathieu Puyade, Carinne Lafon, Thierry Fest, Mikael Roussel, Xavier Cahu, Elsa Bera, Sylvie Daliphard, Fabrice Jardin, Lydia Campos, Françoise Solly, Denis Guyotat, Anne-Cécile Galoisy, Alice Eischen, Caroline Mayeur-Rousse, Blandine Guffroy, Christian Recher, Marie Loosveld, Alice Garnier, Vincent Barlogis, Maria Alessandra Rosenthal, Sophie Brun, Nathalie Contentin, Sébastien Maury, Mary Callanan, Christine Lefebvre, Natacha Maillard, Patricia Okamba, Christophe Ferrand, Olivier Adotevi, Philippe Saas, Fanny Angelot-Delettre, Delphine Binda, Eric Deconinck

Source: Blood Advances, Vol 3, Iss 24, Pp 4238-4251 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920317134; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/10fa6d37e80a40ebb99daae5482013d0

Increased Levels of Interleukin-17A Exosomes in Psoriasis

Authors: Claire Jacquin-Porretaz, Marine Cordonnier, Charlée Nardin, Laura Boullerot, Gaetan Chanteloup, Valentin Vautrot, Olivier Adotevi, Carmen Garrido, Jessica Gobbo, François Aubin

Source: Acta Dermato-Venereologica, Vol 99, Iss 12, Pp 1143-1147 (2019)

Subject Terms: exosomes, psoriasis, il-17, Dermatology, RL1-803

File Description: electronic resource

Relation: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3300; https://doaj.org/toc/0001-5555; https://doaj.org/toc/1651-2057

Access URL: https://doaj.org/article/b8365e4313704a1a9d321620b9437fc8

Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy

Authors: Florence Marliot, Marc Van den Eynde, Franck Pagès, Romain Boidot, Céline Mirjolet, Amos Kirilovsky, Carine El Sissy, Nacilla Haicheur-Adjouri, Viorel Scripcariu, Olivier Adotevi, Laurie Spehner, Elodie Lauret Marie Joseph, Benoît Lecoester, Laura Boullerot, Laurie Rangan, Amélie Marguier, Florent Tochet, Magalie Dosset, Jihane Boustani, Patrice Ravel, Jean-René Pallandre, Francis Bonnefoy, Emmanuel Cornillot

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/7/e002256.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/2c4df4d5a35b4af1b8a7572b3ea26484

First immunotherapeutic CAR-T cells against the immune checkpoint protein HLA-G

Authors: Olivier Adotevi, François Anna, Elodie Bole-Richard, Joel LeMaoult, Marie Escande, Martin Lecomte, Jean-Marie Certoux, Philippe Souque, Francine Garnache, Pierre Langlade-Demoyen, Maria Loustau, Julien Caumartin

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/3/e001998.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/55a6eb05e4d549b48790582481d89419

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape

Authors: Loria Zalmaï, Pierre-Julien Viailly, Sabeha Biichle, Meyling Cheok, Lou Soret, Fanny Angelot-Delettre, Tony Petrella, Marie-Agnès Collonge-Rame, Estelle Seilles, Sandrine Geffroy, Eric Deconinck, Etienne Daguindau, Sabrina Bouyer, Elodie Dindinaud, Victor Baunin, Magali Le Garff-Tavernier, Damien Roos-Weil, Orianne Wagner-Ballon, Véronique Salaun, Jean Feuillard, Sophie Brun, Bernard Drenou, Caroline Mayeur-Rousse, Patricia Okamba, Véronique Dorvaux, Michel Tichionni, Johann Rose, Marie Thérèse Rubio, Marie Christine Jacob, Victoria Raggueneau, Claude Preudhomme, Philippe Saas, Christophe Ferrand, Olivier Adotevi, Christophe Roumier, Fabrice Jardin, Francine Garnache-Ottou, Florian Renosi

Source: Haematologica, Vol 106, Iss 12 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10047; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/74099b909c3e4d95b870c46bcce460cb

PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy

Authors: Paul Nghiem, Martin Cheever, Stanley R Riddell, Steven P Fling, Nirasha Ramchurren, Nathalie Labarrière, Sylvain Simon, Virginie Vignard, Tiffany Beauvais, Brigitte Dreno, Valentin Voillet, Zhong Wu, Camille Dabrowski, Nicolas Jouand, Amir Khammari, Cécile Braudeau, Régis Josien, Olivier Adotevi, Caroline Laheurte, François Aubin, Charles Nardin, Samuel Rulli, Raphael Gottardo, Candice D Church

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/2/e001631.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/e9c7452d81254d408bd2276450f26642

Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases

Authors: Olivier Adotevi, Marie Kroemer, Celia Turco, Laurie Spehner, Julien Viot, Idir Idirène, Adeline Bouard, Elodie Renaude, Marina Deschamps, Yann Godet, Samuel Limat, Bruno Heyd, Marine Jary, Romain Loyon, Christophe Borg

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/2/e001478.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/7bebc9c3f3704540a3a717f1f980b649

The Human Cytomegalovirus Strain DB Activates Oncogenic Pathways in Mammary Epithelial Cells

Authors: Amit Kumar, Manoj Kumar Tripathy, Sébastien Pasquereau, Fatima Al Moussawi, Wasim Abbas, Laurie Coquard, Kashif Aziz Khan, Laetitia Russo, Marie-Paule Algros, Séverine Valmary-Degano, Olivier Adotevi, Stéphanie Morot-Bizot, Georges Herbein

Source: EBioMedicine, Vol 30, Iss , Pp 167-183 (2018)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396418300999; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/0636bae3a29049aaab73f548f78eb6a5