Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintains mouse low-grade glioma growth

Authors: Rasha Barakat, Jit Chatterjee, Rui Mu, Xuanhe Qi, Xingxing Gu, Igor Smirnov, Olivia Cobb, Karen Gao, Angelica Barnes, Jonathan Kipnis, David H. Gutmann

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a76d1fc385104e84bffc95146882c3f4

Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia

Authors: Leonard D. Kuhrt, Edyta Motta, Nirmeen Elmadany, Hannah Weidling, Raphaela Fritsche-Guenther, Ibrahim E. Efe, Olivia Cobb, Jit Chatterjee, Lucy G. Boggs, Marina Schnauß, Sebastian Diecke, Marcus Semtner, Corina Anastasaki, David H. Gutmann, Helmut Kettenmann

Source: Disease Models & Mechanisms, Vol 16, Iss 12 (2023)

Subject Terms: microglia, neurofibromatosis 1, human induced pluripotent stem cells, purinergic receptors, phagocytosis, motility, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/16/12/dmm049861; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/27ffcc79016247599283cd70ac5c43af

The Safety and Effectiveness of Commercially Available Cannabidiol Products for Health and Well-Being: A Randomized, Multi-Arm, Open-Label Waitlist-Controlled Trial

Authors: Jessica Londeree Saleska, Emily K. Pauli, Panteha Rezvan, Olivia Cobb, Jeff Chen, Pelin Thorogood, Miroslav Backonja, Christopher S. Colwell, Derek Loewy, Ethan Russo, Kate Wolitzky-Taylor, Jill Waalen, Ryan Vandrey, Kelsey T. Laird

Source: Integrative Medicine Reports, Vol 1, Iss 1, Pp 215-226 (2022)

Subject Terms: cannabidiol, CBD, anxiety, pain, sleep, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2768-3222

Access URL: https://doaj.org/article/49097bc3fd934842ad4343c608131119

Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling

Authors: Corina Anastasaki, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Suzanne M. Scheaffer, Amanda De Andrade Costa, Anna F. Wilson, Chloe M. Kernan, Ameera H. Zafar, Xia Ge, Joel R. Garbow, Fausto J. Rodriguez, David H. Gutmann

Source: Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-19 (2022)

Subject Terms: Low-grade glioma, Pediatric brain tumor, Pilocytic astrocytoma, NF1, BRAF, Human induced pluripotent stem cells, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/0bce5b7aff7c4c1bb0ec1923cf2a939e

Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

Authors: Corina Anastasaki, Juan Mo, Ji-Kang Chen, Jit Chatterjee, Yuan Pan, Suzanne M. Scheaffer, Olivia Cobb, Michelle Monje, Lu Q. Le, David H. Gutmann

Source: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/da669970414141a2a3165032a695c25b

Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

Authors: Jit Chatterjee, Shilpa Sanapala, Olivia Cobb, Alice Bewley, Andrea K. Goldstein, Elizabeth Cordell, Xia Ge, Joel R. Garbow, Michael J. Holtzman, David H. Gutmann

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e627dfd988e34a69a26d27c59e8d639b

Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth

Authors: Xiaofan Guo, Yuan Pan, Min Xiong, Shilpa Sanapala, Corina Anastasaki, Olivia Cobb, Sonika Dahiya, David H. Gutmann

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6c5c63d7270c439b8c0919d2b7cf92d2