Distinctive protein expression in elderly livers in a Sprague–Dawley rat model of normothermic ex vivo liver machine perfusion

Authors: Maximilian Zimmer, Karl Herbert Hillebrandt, Nathalie Nora Roschke, Steffen Lippert, Oliver Klein, Grit Nebrich, Joseph Maria George Vernon Gassner, Felix Strobl, Johann Pratschke, Felix Krenzien, Igor Maximilian Sauer, Nathanael Raschzok, Simon Moosburner

Source: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)

Subject Terms: Liver transplantation, Proteomics, Oxidative stress, Normothermic machine perfusion, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/97915733214b4c90b2a9ed1e285a1b80

Proteomic analysis of decellularized mice liver and kidney extracellular matrices

Authors: Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher, Benjamin Struecker

Source: Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-16 (2024)

Subject Terms: Decellularized scaffolds, Mice liver/kidney matrisome, Bottom-up proteomics, Tissue engineering, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1754-1611

Access URL: https://doaj.org/article/184b7542c395420292ac63157f983099

Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Authors: Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen, Christof Stamm

Source: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-23 (2023)

Subject Terms: Cell therapy, Direct reprogramming, Fibroblast, Induced cardiomyocyte precursor, Molecular beacon, Myocardial infarction, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/c371854fe11c4e7097810a43c278f286

Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome.

Authors: Nathalie N Roschke, Karl H Hillebrandt, Dietrich Polenz, Oliver Klein, Joseph M G V Gassner, Johann Pratschke, Felix Krenzien, Igor M Sauer, Nathanael Raschzok, Simon Moosburner

Source: PLoS ONE, Vol 19, Iss 4, p e0297497 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297497&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/736b7f9208884f70b0a0e0e156d05e83

Characterization of Anthracycline-induced Cardiotoxicity by 7T Diffusion Tensor Magnetic Resonance Imaging

Authors: Niklas Beyhoff, David Lohr, Arne Thiele, Vera Braun, Max Stahnke, Robert Klopfleisch, Oliver Klein, Anna Foryst-Ludwig, Ulrich Kintscher, Laura Schreiber

Source: Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100678- (2024)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1097664724006690; https://doaj.org/toc/1097-6647

Access URL: https://doaj.org/article/a8b69729c41c430da5739bd9124461a1

Targeting homologous recombination deficiency in uterine leiomyosarcoma

Authors: Genevieve Dall, Cassandra J. Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Joseph H. A. Vissers, Justin Bedő, Jocelyn Penington, Matthew J. Wakefield, Damien Kee, Amandine Carmagnac, Ratana Lim, Kristy Shield-Artin, Briony Milesi, Amanda Lobley, Elizabeth L. Kyran, Emily O’Grady, Joshua Tram, Warren Zhou, Devindee Nugawela, Kym Pham Stewart, Reece Caldwell, Lia Papadopoulos, Ashley P. Ng, Alexander Dobrovic, Stephen B. Fox, Orla McNally, Jeremy D. Power, Tarek Meniawy, Teng Han Tan, Ian M. Collins, Oliver Klein, Stephen Barnett, Inger Olesen, Anne Hamilton, Oliver Hofmann, Sean Grimmond, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker

Source: Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)

Subject Terms: Uterine leiomyosarcoma, Homologous recombination deficiency, PARP inhibitors, Rare cancers, Patient-derived xenografts, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/90697e9e0fe04ca583a35a4167337ba8

Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition

Authors: Roger J. Daly, Andrew M. Scott, Oliver Klein, Matthias Ernst

Source: Molecular Cancer, Vol 21, Iss 1, Pp 1-20 (2022)

Subject Terms: Immuno-oncology, Tumor microenvironment, Targeted therapy, PD-1, PD-L1, CTLA-4, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/71ddc9e416cc475e9dbf1b2c9cd276ac

Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients

Authors: Lena Peter, Désirée Jacqueline Wendering, Stephan Schlickeiser, Henrike Hoffmann, Rebecca Noster, Dimitrios Laurin Wagner, Ghazaleh Zarrinrad, Sandra Münch, Samira Picht, Sarah Schulenberg, Hanieh Moradian, Mir-Farzin Mashreghi, Oliver Klein, Manfred Gossen, Toralf Roch, Nina Babel, Petra Reinke, Hans-Dieter Volk, Leila Amini, Michael Schmueck-Henneresse

Source: Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 52-73 (2022)

Subject Terms: solid organ transplant recipients, SARS-CoV-2 infection, COVID-19, adoptive immunotherapy, T cell therapy, CRISPR-Cas9, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122000286; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/9113c01efc2341409d18184065607cd5

Visualization of Inflammation in Experimental Colitis by Magnetic Resonance Imaging Using Very Small Superparamagnetic Iron Oxide Particles

Authors: Laura Golusda, Anja A. Kühl, Malte Lehmann, Katja Dahlke, Susanne Mueller, Philipp Boehm-Sturm, Jessica Saatz, Heike Traub, Joerg Schnorr, Christian Freise, Matthias Taupitz, Karina Biskup, Véronique Blanchard, Oliver Klein, Ingolf Sack, Britta Siegmund, Daniela Paclik

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: magnetic resonance imaging, inflammatory bowel diseases, extracellular matrix, DSS-induced colitis, transfer colitis, very small superparamagnetic iron oxide nanoparticles, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.862212/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/992889cdd19647b3a55a38ebfa9858e0

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Authors: Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/7/e004668.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/0b1c2b670e1e4ec1b95b97b6b085c47b

Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Authors: Linda Mileshkin, Ben Markman, Oliver Klein, Damien Kee, Jonathan Cebon, Andreas Behren, Matteo Carlino, Bo Gao, Jessica da Gama Duarte, Luke Quigley, Louise Jackett, Richelle Linklater, Andrew Strickland, Clare Scott, Jodie Palmer

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/11/e003156.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/6766e0f0fbac49fbb8002327f10273b3

A rare case of solitary gallbladder metastasis from an early cutaneous melanoma

Authors: Emily Louise Doole, Philip Gan, Oliver Klein

Source: Clinical Case Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)

Subject Terms: case report, metastatic melanoma, post‐partum melanoma, solitary gallbladder metastasis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0904

Access URL: https://doaj.org/article/1863ae2e75174bc2a8b3ae67638c90e5

Anti-programmed cell death protein 1 (anti-PD1) immunotherapy induced autoimmune polyendocrine syndrome type II (APS-2): a case report and review of the literature

Authors: Ashray Gunjur, Oliver Klein, Damien Kee, Jonathan Cebon

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)

Subject Terms: Immune checkpoint inhibitor, PD1 inhibitor, Pembrolizumab, Poly-endocrinopathy, Diabetes mellitus, Hypoadrenalism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0713-y; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/7bab1b461a42463eb3b7aed7196c0fe8

Spatial UBE2N protein expression indicates genomic instability in colorectal cancers

Authors: Timo Gemoll, Elena Miroll, Oliver Klein, Annette Lischka, Murat Eravci, Christoph Thorns, Jens K. Habermann

Source: BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)

Subject Terms: Imaging mass spectrometry, Genomic instability, Aneuploidy, UBE2N, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-019-5856-1; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/e178032f73024c6dbda38eec43effe97

Extracellular vesicles from regenerative human cardiac cells act as potent immune modulators by priming monocytes

Authors: Christien M. Beez, Marion Haag, Oliver Klein, Sophie Van Linthout, Michael Sittinger, Martina Seifert

Source: Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)

Subject Terms: Extracellular vesicles, Exosomes, Cardiac cells, Immunomodulation, CD14+ myeloid suppressive cells, Monocytes, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12951-019-0504-0; https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/3dbf25925da74fcd858c045a8e071e92

PDCD1 Polymorphisms May Predict Response to Anti-PD-1 Blockade in Patients With Metastatic Melanoma

Authors: Sagun Parakh, Ashan Musafer, Sabrina Paessler, Tom Witkowski, Connie S. N. Li Wai Suen, Candani S. A. Tutuka, Matteo S. Carlino, Alexander M. Menzies, Richard A. Scolyer, Jonathan Cebon, Alexander Dobrovic, Georgina V. Long, Oliver Klein, Andreas Behren

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: metastatic melanoma, PD1, polymorphism, predictive biomarker, immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.672521/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/60fdb249cd3241e8afe688013434c093

Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Authors: Oliver Klein, Clare Senko, Matteo S Carlino, Ben Markman, Louise Jackett, Bo Gao, Caroline Lum, Damien Kee, Andreas Behren, Jodie Palmer, Jonathan Cebon

Source: OncoImmunology, Vol 10, Iss 1 (2021)

Subject Terms: adrenocortical carcinoma, anti-pd-1, anti-pd-l1, anti-ctla-4, nivolumab, ipilimumab, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/7f2fc651c58842519396e8f5afbfd47f

The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention

Authors: Ahmed Elsanhoury, Uwe Kühl, Bruno Stautner, Oliver Klein, Alexander Krannich, Daniel Morris, Monika Willner, Ewa Jankowska, Karin Klingel, Sophie Van Linthout, Carsten Tschöpe

Source: Viruses, Vol 14, Iss 2, p 299 (2022)

Subject Terms: myocarditis, human herpesvirus 6, immunosuppression, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/2/299; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/8ab3d618fc8146588d6e2f372f6c6947

Peptide Signatures for Prognostic Markers of Pancreatic Cancer by MALDI Mass Spectrometry Imaging

Authors: Florian N. Loch, Oliver Klein, Katharina Beyer, Frederick Klauschen, Christian Schineis, Johannes C. Lauscher, Georgios A. Margonis, Claudius E. Degro, Wael Rayya, Carsten Kamphues

Source: Biology, Vol 10, Iss 10, p 1033 (2021)

Subject Terms: pancreatic cancer, peptide signatures, MALDI-MSI, risk stratification, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/10/10/1033; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/2892edb449954ce99b5246c09257867f

Deactivation vs. asynchronous pacing - prospective evaluation of a protocol for rhythm management in patients with magnetic resonance conditional pacemakers undergoing adenosine stress cardiovascular magnetic resonance imaging

Authors: Oliver Klein-Wiele, Marietta Garmer, Gianluca Barbone, Rhyan Urbien, Martin Busch, Kaffer Kara, Harald Schäfer, Michael Schulte-Hermes, Birgit Hailer, Dietrich Grönemeyer

Source: BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-7 (2017)

Subject Terms: Pacemaker, MRI conditional, Cardiovascular magnetic resonance, CMR, Adenosine stress, Safety, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12872-017-0579-1; https://doaj.org/toc/1471-2261

Access URL: https://doaj.org/article/3813a1364baa45c2bbc6925bebf93585