Insights into the kinetics and dynamics of the furin-cleaved form of PCSK9

Authors: Oleaga, Carlota, Hay, Joshua, Gurcan, Emma, David, Larry L., Mueller, Paul A., Tavori, Hagai, Shapiro, Michael D., Pamir, Nathalie, Fazio, Sergio

Source: In Journal of Lipid Research 2021 62

Hepatic Sensing Loop Regulates PCSK9 Secretion in Response to Inhibitory Antibodies

Authors: Oleaga, Carlota, Shapiro, Michael D., Hay, Joshua, Mueller, Paul A., Miles, Joshua, Huang, Cecilia, Friz, Emily, Tavori, Hagai, Toth, Peter P., Wójcik, Cezary, Warden, Bruce A., Purnell, Jonathan Q., Duell, P. Barton, Pamir, Nathalie, Fazio, Sergio

Source: Journal of the American College of Cardiology. 78(14):1437-1449

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Unusual responses to PCSK9 inhibitors in a clinical cohort utilizing a structured follow-up protocol

Authors: Warden, Bruce A., Miles, Joshua R., Oleaga, Carlota, Ganda, Om P., Duell, P. Barton, Purnell, Jonathan Q., Shapiro, Michael D., Fazio, Sergio

Source: In American Journal of Preventive Cardiology March 2020 1

Microphysiological heart–liver body-on-a-chip system with a skin mimic for evaluating topical drug deliveryElectronic supplementary information (ESI) available. See DOI: 10.1039/c9lc00861f

Authors: Pires de MelloThese authors contributed equally., Camilly P., Carmona-Moran, Carlos, McAleer, Christopher W., Perez, Julian, Coln, Elizabeth A., Long, Christopher J., Oleaga, Carlota, Riu, Anne, Note, Reine, Teissier, Silvia, Langer, Jessica, Hickman, James J.

Source: Lab on a chip. 20(4):749-759

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Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system

Authors: Oleaga, Carlota, Riu, Anne, Rothemund, Sandra, Lavado, Andrea, McAleer, Christopher W., Long, Christopher J., Persaud, Keisha, Narasimhan, Narasimhan Sriram, Tran, My, Roles, Jeffry, Carmona-Moran, Carlos A., Sasserath, Trevor, Elbrecht, Daniel H., Kumanchik, Lee, Bridges, L. Richard, Martin, Candace, Schnepper, Mark T., Ekman, Gail, Jackson, Max, Wang, Ying I., Note, Reine, Langer, Jessica, Teissier, Silvia, Hickman, James J.

Source: In Biomaterials November 2018 182:176-190

A phenotypic in vitro model for the main determinants of human whole heart function

Authors: Stancescu, Maria, Molnar, Peter, McAleer, Christopher W., McLamb, William, Long, Christopher J., Oleaga, Carlota, Prot, Jean-Matthieu, Hickman, James J.

Source: In Biomaterials August 2015 60:20-30

A functional long‐term 2D serum‐free human hepatic in vitro system for drug evaluation

Authors: Oleaga, Carlota, Bridges, L. Richard, Persaud, Keisha, McAleer, Christopher W., Long, Christopher J., Hickman, James J.

Source: Biotechnology progress. 37(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116434860.0x000001&indx=1&recIds=ETOCvdc_100116434860.0x000001

Role of PAI-1 in hepatic steatosis and dyslipidemia

Authors: Levine, Joshua A., Oleaga, Carlota, Eren, Mesut, Amaral, Ansel P., Shang, Meng, Lux, Elizabeth, Khan, Sadiya S., Shah, Sanjiv J., Omura, Yasuhiro, Pamir, Nathalie, Hay, Joshua, Barish, Grant, Miyata, Toshio, Tavori, Hagai, Fazio, Sergio, Vaughan, Douglas E.

Source: Scientific reports. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194143978.0x000001&indx=1&recIds=ETOCvdc_100194143978.0x000001

How multi-organ microdevices can help foster drug development

Authors: Esch, Mandy B., Smith, Alec S.T., Prot, Jean-Matthieu, Oleaga, Carlota, Hickman, James J., Shuler, Michael L.

Source: In Advanced Drug Delivery Reviews 20 April 2014 69-70:158-169

Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics

Authors: Oleaga, Carlota, Welten, Sabine, Belloc, Audrey, Solé, Anna, Rodriguez, Laura, Mencia, Núria, Selga, Elisabet, Tapias, Alicia, Noé, Veronique, Ciudad, Carlos J.

Source: In Biochemical Pharmacology 15 December 2012 84(12):1581-1591

Human‐on‐a‐Chip Systems: Long‐Term Electrical and Mechanical Function Monitoring of a Human‐on‐a‐Chip System (Adv. Funct. Mater. 8/2019)

Authors: Oleaga, Carlota, Lavado, Andrea, Riu, Anne, Rothemund, Sandra, Carmona‐Moran, Carlos A., Persaud, Keisha, Yurko, Andrew, Lear, Jennifer, Narasimhan, Narasimhan Sriram, Long, Christopher J., Sommerhage, Frank, Bridges, Lee Richard, Cai, Yunqing, Martin, Candace, Schnepper, Mark T., Goswami, Arindom, Note, Reine, Langer, Jessica, Teissier, Silvia, Cotovio, José, Hickman, James J.

Source: Advanced functional materials. 29(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188257983.0x000001&indx=1&recIds=ETOCvdc_100188257983.0x000001

Long‐Term Electrical and Mechanical Function Monitoring of a Human‐on‐a‐Chip System

Authors: Oleaga, Carlota, Lavado, Andrea, Riu, Anne, Rothemund, Sandra, Carmona‐Moran, Carlos A., Persaud, Keisha, Yurko, Andrew, Lear, Jennifer, Narasimhan, Narasimhan Sriram, Long, Christopher J., Sommerhage, Frank, Bridges, Lee Richard, Cai, Yunqing, Martin, Candace, Schnepper, Mark T., Goswami, Arindom, Note, Reine, Langer, Jessica, Teissier, Silvia, Cotovio, José, Hickman, James J.

Source: Advanced functional materials. 29(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188257676.0x000001&indx=1&recIds=ETOCvdc_100188257676.0x000001

Unusual Responses to PCSK9 Inhibitors in a Real-world Clinical Cohort

Authors: Warden, Bruce A., Nakrani, Monark N., Oleaga, Carlota, Ganda, Om P., Duell, P. Barton, Purnell, Jonathan Q., Shapiro, Michael D., Fazioa, Sergio

Source: In American Journal of Preventive Cardiology September 2020 3 Supplement

CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract.

Authors: Oleaga, Carlota¹, García, Miriam¹, Solé, Anna¹, Ciudad, Carlos¹, Izquierdo-Pulido, Maria², Noé, Véronique¹ vnoe@ub.edu

Source: European Journal of Nutrition. Jun2012, Vol. 51 Issue 4, p465-476. 12p. 5 Graphs.

Subject Terms: *BREAST tumors, *FLAVONOIDS, *ANALYSIS of variance, *BIOPHYSICS, *CACAO, *CELL culture, *GENE expression, *RESEARCH methodology, *OXIDOREDUCTASES, *POLYMERASE chain reaction, *PROBABILITY theory, *RESEARCH funding, *STATISTICS, *T-test (Statistics), *TAMOXIFEN, *GENOMICS, *DATA analysis, *DATA analysis software, *OLIGONUCLEOTIDE arrays, *GENE expression profiling, *GENETICS, *THERAPEUTICS

A human in vitro platform for the evaluation of pharmacology strategies in cardiac ischemia.

Authors: Oleaga, Carlota¹, Jalilvand, Golareh¹, Legters, Gregg¹, Martin, Candace¹, Ekman, Gail¹, McAleer, Christopher W.^1,2, Long, Christopher J.^1,2, Hickman, James J.^1,2, jhickman@ucf.edu

Source: APL Bioengineering; Sep2019, Vol. 3 Issue 3, pN.PAG-N.PAG, 8p

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