Emergent and underexplored oncolytic viruses for treating pediatric central nervous system tumors

Authors: Granha, Isabela, Sartorelli, Gustavo, Okamoto, Oswaldo Keith, Jandrey, Elisa Helena Farias

Source: In EJC Paediatric Oncology June 2024 3

Genetically modified ZIKA virus as a microRNA-sensitive oncolytic virus against central nervous system tumors

Authors: Novaes, Gabriela Machado ^{1, 9}, Lima, Caroline ^{1, 9}, Longo, Carla ¹, Machado, Pedro Henrique ¹, Silva, Thais Peron ¹, Olberg, Giovanna Gonçalves de Oliveira ¹, Módolo, Diego Grando ¹, Pereira, Márcia Cristina Leite ¹, Santos, Tiago Goss ², Zatz, Mayana ^{3, 8}, Lagares, David ^{4, 8}, de Franco, Marcelo ^{5, 8}, Ho, Paulo Lee ^{6, 8}, Bulstrode, Harry ^{7, 8}, Okamoto, Oswaldo Keith ^{3, 8}, Kaid, Carolini ^{1, 8, ∗}

Source: In Molecular Therapy 7 February 2024 32(2):440-456

Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesis

Authors: Scorza Fúlvio A, da Silva Alexandre V, Pansani Aline P, Bonone Felipe M, Janjoppi Luciana, Okamoto Oswaldo K, Cavalheiro Esper A

Source: BMC Genomics, Vol 11, Iss 1, p 230 (2010)

Subject Terms: Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2164/11/230; https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/065eb9017ec047e0ba30baa2940a565e

Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites

Authors: Moreira-Filho Carlos A, Nunes Fabio D, Okamoto Oswaldo K, Michaluart Pedro, Alvares Adriana M, Severino Patricia, Tajara Eloiza H

Source: BMC Research Notes, Vol 1, Iss 1, p 113 (2008)

Subject Terms: Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.biomedcentral.com/1756-0500/1/113; https://doaj.org/toc/1756-0500

Access URL: https://doaj.org/article/a55fa2c56b6a4d0f950c043b1a30fa10

Common molecular pathways involved in human CD133+/CD34+ progenitor cell expansion and cancer

Authors: Vêncio Ricardo Z, Marti Luciana C, Carvalho Ana Carolina SR, Okamoto Oswaldo, Moreira-Filho Carlos A

Source: Cancer Cell International, Vol 7, Iss 1, p 11 (2007)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.cancerci.com/content/7/1/11; https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/9be08ea7115a4f24a73d160bdeb2e782

Functional assessment of donated human embryos for the generation of pluripotent embryonic stem cell lines

Authors: Ceschin, Ianaê I, Ceschin, Alvaro P, Joya, Maria S, Mitsugi, Thiago G, Nishikawa, Lucileine K, Krepischi, Ana CV, Okamoto, Oswaldo K

Source: Reproductive biomedicine online. 46(3):491-501

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184488555.0x000001&indx=1&recIds=ETOCvdc_100184488555.0x000001

Differential Replication and Oncolytic Effects of Zika Virus in Aggressive CNS Tumor Cells: Insights from Organoid and Tumoroid Models.

Authors: Ferreira, Rodolfo Sanches, Jandrey, Elisa Helena Farias, Granha, Isabela, Endo, Alice Kei, Ferreira, Raiane Oliveira, Araujo, Bruno Henrique Silva, Zatz, Mayana, Okamoto, Oswaldo Keith

Source: Viruses (1999-4915); Nov2024, Vol. 16 Issue 11, p1764, 14p

Subject Terms: CENTRAL nervous system cancer, CENTRAL nervous system tumors, ZIKA virus infections, TERATOMA, ONCOLYTIC virotherapy, CANCER cell culture

Report of a clinical and laboratory management of cell therapy for knee cartilage in the face of mycoplasma contamination

Authors: Zorzi, Alessandro Rozim, Antonioli, Eliane, Godoy, Juliana Aparecida Preto de, Okamoto, Oswaldo Keith, Kondo, Andrea Tiemi, Kutner, José Mauro, Kaleka, Camila Cohen, Cohen, Moisés, Ferretti, Mario

Source: einstein (São Paulo). January 2022 20

Subject Terms: Knee, Cartilage, Cell-and tissue-based therapy, Chondrocytes, Mycoplasma, Cell culture techniques

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100511

Safety, Tumor Reduction, and Clinical Impact of Zika Virus Injection in Dogs with Advanced-Stage Brain Tumors

Authors: Kaid, Carolini, Madi, Raquel Azevedo dos Santos, Astray, Renato, Goulart, Ernesto, Caires-Junior, Luiz Carlos, Mitsugi, Thiago Giove, Moreno, Ana Carolina Ramos, Castro-Amarante, Maria Fernanda, Pereira, Lennon Ramos, Porchia, Bruna Felício Milazzotto Maldonado, de Andrade, Thais Oliveira, Landini, Vivian, Sanches, Daniel Soares, Pires, Carolina Gonçalves, Tanioka, Rubens Koji Oliveira, Pereira, Marcia C.L., Barbosa, Igor Neves, Massoco, Cristina O., Ferreira, Luís Carlos de Souza, Okamoto, Oswaldo Keith, Zatz, Mayana

Source: In Molecular Therapy 6 May 2020 28(5):1276-1286

Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis

Authors: Kaid, Carolini, Assoni, Amanda, Marçola, Marina, Semedo-Kuriki, Patricia, Bortolin, Raul Hernandes, Carvalho, Valdemir Melechco, Okamoto, Oswaldo Keith

Source: In Brain Research 1 March 2020 1730

An Extended Flow Cytometry Evaluation of ex Vivo Expanded NK Cells Using K562.Clone1, a Feeder Cell Line Manufactured in Brazil

Authors: Watanabe, Caroline Mitiká, Suzuki, Caroline Ishihama, dos Santos, Alessandro Marins, Aloia, Thiago Pinheiro Arrais, Lee, Grace, Wald, David, Okamoto, Oswaldo Keith, de Azevedo, Julia T. Cottas, de Godoy, Juliana Aparecida Preto, Santos, Fabio P.S., Weinlich, Ricardo, Kerbauy, Lucila N., Kutner, Jose Mauro, Paiva, Raquel de Melo Alves, Hamerschlak, Nelson

Source: Transplantation and Cellular Therapy; November 2024, Vol. 30 Issue: 11 p1063.e1-1063.e19, 95689p

Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1L39R Linked Amyotrophic Lateral Sclerosis

Authors: Rajpurohit, Chetan Singh, Kumar, Vivek, Cheffer, Arquimedes, Oliveira, Danyllo, Ulrich, Henning, Okamoto, Oswaldo Keith, Zatz, Mayana, Ansari, Uzair Ahmad, Khanna, Vinay Kumar, Pant, Aditya Bhushan

Source: Molecular neurobiology. 57(10):4117-4133

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172095937.0x000001&indx=1&recIds=ETOCvdc_100172095937.0x000001

Circulating Gastric Cancer Stem Cells as Blood Screening and Prognosis Factor in Gastric Cancer.

Authors: Becerril-Rico, Jared, Grandvallet-Contreras, Julian, Ruíz-León, M. Patricia, Dorantes-Cano, Sebastián, Ramírez-Vidal, Lizbeth, Tinajero-Rodríguez, José M., Ortiz-Sánchez, Elizabeth, Keith Okamoto, Oswaldo

Source: Stem Cells International; 8/8/2024, Vol. 2024, p1-7, 7p

Subject Terms: MONONUCLEAR leukocytes, CANCER stem cells, LYMPHATIC metastasis, PROGNOSIS, STOMACH cancer

MiR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors

Authors: Kaid, Carolini, Jordan, Dione, Bueno, Heloisa Maria de Siqueira, Araujo, Bruno Henrique Silva, Assoni, Amanda, Okamoto, Oswaldo Keith

Source: Molecular oncology. 13(12):2574-2587

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094336882.0x000001&indx=1&recIds=ETOCvdc_100094336882.0x000001

Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro

Authors: Araujo, Bruno H. S., Kaid, Carolini, De Souza, Janaina S., Gomes da Silva, Sérgio, Goulart, Ernesto, Caires, Luiz C. J., Musso, Camila M., Torres, Laila B., Ferrasa, Adriano, Herai, Roberto, Zatz, Mayana, Okamoto, Oswaldo K., Cavalheiro, Esper A.

Source: Molecular neurobiology. 55(7):5962-5975

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128583000.0x000001&indx=1&recIds=ETOCvdc_100128583000.0x000001

IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS‐associated amyotrophic lateral sclerosis.

Authors: Assoni, Amanda Faria, Guerrero, Erika N., Wardenaar, René, Oliveira, Danyllo, Bakker, Petra L., Alves, Luciana M., Carvalho, Valdemir M., Okamoto, Oswaldo Keith, Zatz, Mayana, Foijer, Floris

Source: Brain Pathology; Jan2024, Vol. 34 Issue 1, p1-16, 16p

Subject Terms: PROTEIN synthesis, MOTOR neurons, OXIDATIVE stress, INDUCED pluripotent stem cells, AMYOTROPHIC lateral sclerosis, MOTOR neuron diseases, GENE expression

Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma.

Authors: Faria Assoni, Amanda, Giove Mitsugi, Thiago, Wardenaar, René, Oliveira Ferreira, Raiane, Farias Jandrey, Elisa Helena, Machado Novaes, Gabriela, Fonseca de Oliveira Granha, Isabela, Bakker, Petra, Kaid, Carolini, Zatz, Mayana, Foijer, Floris, Keith Okamoto, Oswaldo

Source: Scientific Reports; 11/9/2023, Vol. 13 Issue 1, p1-13, 13p

Subject Terms: MEDULLOBLASTOMA, AMYOTROPHIC lateral sclerosis, MEMBRANE proteins, CELL proliferation, NEURODEGENERATION

The role of DNA repair in the pluripotency and differentiation of human stem cells

Authors: Rocha, Clarissa Ribeiro Reily, Lerner, Leticia Koch, Okamoto, Oswaldo Keith, Marchetto, Maria Carolina, Menck, Carlos Frederico Martins

Source: In Mutation Research-Reviews in Mutation Research January-March 2013 752(1):25-35

Aberrant signaling pathways in medulloblastomas: a stem cell connection

Authors: Rodini, Carolina Oliveira, Suzuki, Daniela Emi, Nakahata, Adriana Miti, Pereira, Márcia Cristina Leite, Janjoppi, Luciana, Toledo, Silvia Regina Caminada, Okamoto, Oswaldo Keith

Source: Arquivos de Neuro-Psiquiatria. December 2010 68(6)

Subject Terms: medulloblastoma, neurobiology, signal transduction, stem cells, transforming growth factor beta, biological therapy

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600021

Células-tronco derivadas de tecido adiposo humano: desafios atuais e perspectivas clínicas

Authors: Yarak, Samira, Okamoto, Oswaldo Keith

Source: Anais Brasileiros de Dermatologia. October 2010 85(5)

Subject Terms: Adipócitos, Células-tronco adultas, Tecido adiposo, Terapia tissular

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962010000500008