Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypes

Authors: Iwata-Endo, Kuniyuki ^{1, 2, 11}, Sahashi, Kentaro ^{2, 11}, Kawai, Kaori ^{2, 3, 11}, Fujioka, Yusuke ^{1, 2}, Okada, Yohei ⁴, Watanabe, Eri ⁵, Iwade, Nobuyuki ², Ishibashi, Minaka ², Mohammad, Moniruzzaman ¹, Aldoghachi, Asraa Faris ¹, Tuerde, Dilina ², Fujiwara, Tsuyoshi ⁶, Hirai, Shinobu ⁷, Okado, Haruo ⁷, Katsuno, Masahisa ^{2, 3, 8}, Watanabe, Hirohisa ⁹, Kanamitsu, Kayoko ⁵, Neya, Masahiro ⁶, Ishigaki, Shinsuke ^{1, 2, ∗}, Sobue, Gen ^{10, ∗∗}

Source: In Molecular Therapy - Nucleic Acids 10 June 2025 36(2)

Impact of feeding age on cognitive impairment in mice with Disrupted-In-Schizophrenia 1 (Disc1) mutation under a high sucrose diet

Authors: Park, Jonghyuk, Shimbo, Hiroko, Tamura, Shoko, Tomoda, Toshifumi, Hikida, Takatoshi, Okado, Haruo, Hirai, Shinobu

Source: In Behavioural Brain Research 5 January 2025 476

Disease specific brain capillary angiopathy in schizophrenia, bipolar disorder, and Alzheimer's disease

Authors: Hirai, Shinobu, Sakuma, Atsuhiro, Kunii, Yasuto, Shimbo, Hiroko, Hino, Mizuki, Izumi, Ryuta, Nagaoka, Atsuko, Yabe, Hirooki, Kojima, Rika, Seki, Erika, Arai, Nobutaka, Komori, Takashi, Okado, Haruo

Source: In Journal of Psychiatric Research July 2023 163:74-79

Serotonergic neurons control cortical neuronal intracellular energy dynamics by modulating astrocyte-neuron lactate shuttle

Authors: Natsubori, Akiyo, Hirai, Shinobu, Kwon, Soojin, Ono, Daisuke, Deng, Fei, Wan, Jinxia, Miyazawa, Momoka, Kojima, Takashi, Okado, Haruo, Karashima, Akihiro, Li, Yulong, Tanaka, Kenji F., Honda, Makoto

Source: In iScience 20 January 2023 26(1)

Early-life stress induces the development of Alzheimer's disease pathology via angiopathy

Authors: Tanaka, Tomoko, Hirai, Shinobu, Hosokawa, Masato, Saito, Takashi, Sakuma, Hiroshi, Saido, Takaomi, Hasegawa, Masato, Okado, Haruo

Source: In Experimental Neurology March 2021 337

Corticobasal ganglia projecting neurons are required for juvenile vocal learning but not for adult vocal plasticity in songbirds

Authors: Sánchez-Valpuesta, Miguel, Suzuki, Yumeno, Shibata, Yukino, Toji, Noriyuki, Ji, Yu, Afrin, Nasiba, Asogwa, Chinweike Norman, Kojima, Ippei, Mizuguchi, Daisuke, Kojima, Satoshi, Okanoya, Kazuo, Okado, Haruo, Kobayashi, Kenta

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Nov 01. 116(45), 22833-22843.

Access URL: https://www.jstor.org/stable/26860630

Maternal diabetes in early pregnancy, and psychotic experiences and depressive symptoms in 10-year-old offspring: A population-based birth cohort study

Authors: Yamasaki, Syudo, Ando, Shuntaro, Richards, Marcus, Hatch, Stephani L., Koike, Shinsuke, Fujikawa, Shinya, Kanata, Sho, Endo, Kaori, Morimoto, Yuko, Arai, Makoto, Okado, Haruo, Usami, Satoshi, Furukawa, Toshiaki A., Hiraiwa-Hasegawa, Mariko, Kasai, Kiyoto, Nishida, Atsushi

Source: In Schizophrenia Research April 2019 206:52-57

Minocycline prevents early age-related cognitive decline in a mouse model of intellectual disability caused by ZBTB18/RP58 haploinsufficiency.

Authors: Tanaka, Tomoko, Hirai, Shinobu, Manabe, Hiroyuki, Endo, Kentaro, Shimbo, Hiroko, Nishito, Yasumasa, Horiuchi, Junjiro, Yoshitane, Hikari, Okado, Haruo

Source: Journal of Neuroinflammation; 10/12/2024, Vol. 21 Issue 1, p1-13, 13p

Subject Terms: DNA repair, DNA damage, DENTATE gyrus, MITOCHONDRIAL DNA, COGNITION disorders

Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1

Authors: Kita, Motoko, Nakae, Jun, Kawano, Yoshinaga, Asahara, Hiroshi, Takemori, Hiroshi, Okado, Haruo, Itoh, Hiroshi

Source: In iScience 22 February 2019 12:87-101

Regulation of brain development and brain function by the transcriptional repressor RP58

Authors: Okado, Haruo

Source: In Brain Research 15 February 2019 1705:15-23

Altered GluA1 (Gria1) Function and Accumbal Synaptic Plasticity in the ClockΔ19 Model of Bipolar Mania

Authors: Parekh, Puja K., Becker-Krail, Darius, Sundaravelu, Poornima, Ishigaki, Shinsuke, Okado, Haruo, Sobue, Gen, Huang, Yanhua, McClung, Colleen A.

Source: In Biological Psychiatry 1 December 2018 84(11):817-826

Silencing of FUS in the common marmoset (Callithrix jacchus) brain via stereotaxic injection of an adeno-associated virus encoding shRNA

Authors: Endo, Kuniyuki, Ishigaki, Shinsuke, Masamizu, Yoshito, Fujioka, Yusuke, Watakabe, Akiya, Yamamori, Tetsuo, Hatanaka, Nobuhiko, Nambu, Atsushi, Okado, Haruo, Katsuno, Masahisa, Watanabe, Hirohisa, Matsuzaki, Masanori, Sobue, Gen

Source: In Neuroscience Research May 2018 130:56-64

Synaptic transmission from subplate neurons controls radial migration of neocortical neurons

Authors: Ohtaka-Maruyama, Chiaki, Okamoto, Mayumi, Endo, Kentaro, Oshima, Minori, Kaneko, Noe, Yura, Kei, Okado, Haruo, Miyata, Takaki, Maeda, Nobuaki

Source: Science, 2018 Apr . 360(6386), 313-317.

Access URL: https://www.jstor.org/stable/26498720

Sequential Exocytosis of Insulin Granules Is Associated with Redistribution of SNAP25

Authors: Takahashi, Noriko, Hatakeyama, Hiroyasu, Okado, Haruo, Miwa, Akiko, Kishimoto, Takuya, Kojima, Tatsuya, Abe, Teruo, Kasai, Haruo

Source: The Journal of Cell Biology, 2004 Apr . 165(2), 255-262.

Access URL: https://www.jstor.org/stable/1622191

3′UTR Length-Dependent Control of SynGAP Isoform α2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function

Authors: Yokoi, Satoshi, Udagawa, Tsuyoshi, Fujioka, Yusuke, Honda, Daiyu, Okado, Haruo, Watanabe, Hirohisa, Katsuno, Masahisa, Ishigaki, Shinsuke, Sobue, Gen

Source: In Cell Reports 26 September 2017 20(13):3071-3084

Glia-Synapse Interaction through Ca 2+ -Permeable AMPA Receptors in Bergmann Glia

Authors: Iino, Masae, Goto, Kaori, Kakegawa, Wataru, Okado, Haruo, Sudo, Makoto, Ishiuchi, Shogo, Miwa, Akiko, Takayasu, Yukihiro, Saito, Izumu, Tsuzuki, Keisuke, Ozawa, Seiji

Source: Science, 2001 May 01. 292(5518), 926-929.

Access URL: https://www.jstor.org/stable/3083601

AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate

Authors: Hirai, Shinobu, Hotta, Kohji, Kubo, Yoshihiro, Nishino, Atsuo, Okabe, Shigeo, Okamura, Yasushi, Okado, Haruo

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Apr 01. 114(15), 3939-3944.

Access URL: https://www.jstor.org/stable/26480842

Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43

Authors: Nonaka, Takashi, Suzuki, Genjiro, Tanaka, Yoshinori, Kametani, Fuyuki, Hirai, Shinobu, Okado, Haruo, Miyashita, Tomoyuki, Saitoe, Minoru, Akiyama, Haruhiko, Masai, Hisao, Hasegawa, Masato

Source: In Journal of Biological Chemistry 11 March 2016 291(11):5473-5483

In Silico Analyses of Vertebrate G-Protein-Coupled Receptor Fusions United With or Without an Additional Transmembrane Sequence Indicate Classification into Three Groups of Linkers.

Authors: Kamiya, Toshio, Masuko, Takashi, Borroto-Escuela, Dasiel Oscar, Okado, Haruo, Nakata, Hiroyasu

Source: Protein Journal; Apr2024, Vol. 43 Issue 2, p225-242, 18p

Subject Terms: RECEPTOR-interacting proteins, VERTEBRATES, SEA anemones, AMPHIBIANS, REPTILES

Benzodiazepines induce sequelae in immature mice with inflammation-induced status epilepticus

Authors: Nakajima, Keisuke, Hirai, Shinobu, Morio, Tomohiro, Okado, Haruo

Source: In Epilepsy & Behavior November 2015 52 Part A:180-186