The atypical IκB family member Bcl3 determines differentiation and fate of intestinal RORγt+ regulatory T-cell subsets

Authors: Köhler, Amelie, Geiselhöringer, Anna-Lena, Kolland, Daphne, Kreft, Luisa, Wichmann, Nina, Hils, Miriam, Pasztoi, Maria, Zurkowski, Elena, Vogt, Johannes, Kübelbeck, Tanja, Biedermann, Tilo, Schmitz, Ingo, Hansen, Wiebke, Kramer, Daniela, Gaida, Matthias M., Schmidt-Weber, Carsten B., Hoevelmeyer, Nadine, Ohnmacht, Caspar

Source: In Mucosal Immunology August 2024 17(4):673-691

IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4

Authors: Hils, Miriam, Hoffard, Nils, Iuliano, Caterina, Kreft, Luisa, Chakrapani, Neera, Swiontek, Kyra, Fischer, Konrad, Eberlein, Bernadette, Köberle, Martin, Fischer, Jörg, Hilger, Christiane, Ohnmacht, Caspar, Kaesler, Susanne, Wölbing, Florian, Biedermann, Tilo

Source: In The Journal of Allergy and Clinical Immunology April 2024 153(4):1050-1062

Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma

Authors: Lechner, Antonie, Henkel, Fiona D.R., Hartung, Franziska, Bohnacker, Sina, Alessandrini, Francesca, Gubernatorova, Ekaterina O., Drutskaya, Marina S., Angioni, Carlo, Schreiber, Yannick, Haimerl, Pascal, Ge, Yan, Thomas, Dominique, Kabat, Agnieszka M., Pearce, Edward J., Ohnmacht, Caspar, Nedospasov, Sergei A., Murray, Peter J., Chaker, Adam M., Schmidt-Weber, Carsten B., Esser-von Bieren, Julia

Source: Journal of allergy and clinical immunology. 149(6):2078-2090

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164767713.0x000001&indx=1&recIds=ETOCvdc_100164767713.0x000001

Diversity of T Helper and Regulatory T Cells and Their Contribution to the Pathogenesis of Allergic Diseases

Authors: Ohnmacht, Caspar, Eyerich, Stefanie

Source: Handbook of experimental pharmacology. 268:265-296

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628264798&indx=1&recIds=ETOCRN628264798

Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunity.

Authors: Geiselhöringer, Anna-Lena, Kolland, Daphne, Patt, Arisha Johanna, Hammann, Linda, Köhler, Amelie, Kreft, Luisa, Wichmann, Nina, Hils, Miriam, Ruedl, Christiane, Riemann, Marc, Biedermann, Tilo, Anz, David, Diefenbach, Andreas, Voehringer, David, Schmidt-Weber, Carsten B., Straub, Tobias, Pasztoi, Maria, Ohnmacht, Caspar

Source: Nature Communications; 10/23/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: REGULATORY T cells, TRANSCRIPTION factors, DENDRITIC cells, INTESTINAL infections, IMMUNOLOGICAL tolerance, T cells, HOMEOSTASIS

Defining Dysbiosis in Inflammatory Bowel Disease

Authors: de Jong, Renske J., Ohnmacht, Caspar

Source: In Immunity 15 January 2019 50(1):8-10

Dendritic Cell Accumulation in the Gut and Central Nervous System Is Differentially Dependent on α4 Integrins

Authors: Sie, Christopher, Perez, Laura Garcia, Kreutzfeldt, Mario, Potthast, Maria, Ohnmacht, Caspar, Merkler, Doron, Huber, Samuel, Krug, Anne, Korn, Thomas

Source: Journal of immunology. 203(6):1417-1427

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621485750&indx=1&recIds=ETOCRN621485750

Aire-expressing ILC3-like cells in the lymph node display potent APC features

Authors: Yamano, Tomoyoshi, Dobeš, Jan, Vobořil, Matouš, Steinert, Madlen, Brabec, Tomáš, Ziętara, Natalia, Dobešová, Martina, Ohnmacht, Caspar, Laan, Martti, Peterson, Part

Source: Journal of experimental medicine. 216(5):1027-1037

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620019390&indx=1&recIds=ETOCRN620019390

Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions—Brief Report

Authors: van der Vorst, Emiel P.C., Mandl, Manuela, Müller, Madeleine, Neideck, Carlos, Jansen, Yvonne, Hristov, Michael, Gencer, Selin, Peters, Linsey J.F., Meiler, Svenja, Feld, Micha, Geiselhöringer, Anna-Lena, de Jong, Renske J., Ohnmacht, Caspar, Noels, Heidi, Soehnlein, Oliver, Drechsler, Maik, Weber, Christian, Döring, Yvonne

Source: Arteriosclerosis, thrombosis, and vascular biology. 39(4):685-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178204863.0x000001&indx=1&recIds=ETOCvdc_100178204863.0x000001

D-tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease

Authors: Kepert, Inge, Fonseca, Juliano, Müller, Constanze, Milger, Katrin, Hochwind, Kerstin, Kostric, Matea, Fedoseeva, Maria, Ohnmacht, Caspar, Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, Eickelberg, Oliver, Schloter, Michael, Hartmann, Anton, Schmitt-Kopplin, Philippe, Krauss-Etschmann, Susanne

Source: In The Journal of Allergy and Clinical Immunology May 2017 139(5):1525-1535

Activation of the aryl hydrocarbon receptor improves allergen-specific immunotherapy of murine allergic airway inflammation: a novel adjuvant option?

Authors: Heine, Sonja, Alessandrini, Francesca, Grosch, Johannes, Graß, Carina, Heldner, Alexander, Schnautz, Benjamin, Grosch, Johanna, Buters, Jeroen, Slusarenko, Benjamin O., Krappmann, Daniel, Fallarino, Francesca, Ohnmacht, Caspar, Schmidt-Weber, Carsten B., Blank, Simon

Source: Frontiers in Immunology; 2024, p1-19, 19p

Subject Terms: ARYL hydrocarbon receptors, TRANSCRIPTION factors, TREATMENT effectiveness, IMMUNOTHERAPY, TH2 cells

CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.

Authors: Immler, Roland, Nussbaumer, Katrin, Doerner, Axel, El Bounkari, Omar, Huber, Silke, Abisch, Janine, Napoli, Matteo, Schmidt, Sarah, Margraf, Andreas, Pruenster, Monika, Rohwedder, Ina, Lange-Sperandio, Baerbel, Mall, Marcus A., de Jong, Renske, Ohnmacht, Caspar, Bernhagen, Juergen, Voehringer, David, Marth, Jamey D., Frommhold, David, Sperandio, Markus

Source: Proceedings of the National Academy of Sciences of the United States of America; 5/7/2024, Vol. 121 Issue 19, p1-11, 15p

Subject Terms: EOSINOPHILS, HOMEOSTASIS, PERITONEUM, ALLERGIES, ADIPOSE tissues

Tolerance to the Intestinal Microbiota Mediated by ROR(γt)+ Cells

Authors: Ohnmacht, Caspar

Source: In Trends in Immunology July 2016 37(7):477-486

Comparative Metagenomic Analysis of Bacteriophages and Prophages in Gnotobiotic Mouse Models.

Authors: Ishola, Oluwaseun A., Kublik, Susanne, Durai Raj, Abilash Chakravarthy, Ohnmacht, Caspar, Schulz, Stefanie, Foesel, Bärbel U., Schloter, Michael

Source: Microorganisms; Feb2024, Vol. 12 Issue 2, p255, 17p

Subject Terms: MOBILE genetic elements, HORIZONTAL gene transfer, MICROBIAL diversity, LABORATORY mice, AMINO acid metabolism, BACTERIOPHAGES, BACTERIAL diversity

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

Authors: Papaioannou, Nikos E., Salei, Natallia, Rambichler, Stephan, Ravi, Kaushikk, Popovic, Jelena, Küntzel, Vanessa, Lehmann, Christian H. K., Fiancette, Remi, Salvermoser, Johanna, Gajdasik, Dominika W., Mettler, Ramona, Messerer, Denise, Carrelha, Joana, Ohnmacht, Caspar, Haller, Dirk, Stumm, Ralf, Straub, Tobias, Jacobsen, Sten Eirik W., Schulz, Christian, Withers, David R., Schotta, Gunnar, Dudziak, Diana, Schraml, Barbara U.

Source: Nature communications. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193133202.0x000001&indx=1&recIds=ETOCvdc_100193133202.0x000001

The microbiota regulates type 2 immunity through RORγt + T cells

Authors: Ohnmacht, Caspar, Park, Joo-Hong, Cording, Sascha, Wing, James B., Atarashi, Koji, Obata, Yuuki, Gaboriau-Routhiau, Valérie, Marques, Rute, Dulauroy, Sophie, Fedoseeva, Maria, Busslinger, Meinrad, Cerf-Bensussan, Nadine, Boneca, Ivo G., Voehringer, David, Hase, Koji, Honda, Kenya, Sakaguchi, Shimon, Eberl, Gérard

Source: Science, 2015 Aug . 349(6251), 989-993.

Access URL: http://www.jstor.org/stable/24749249

˜Dieœ Bedeutung von angeborenen Effektorzellen während einer Typ-2-Immunantwort :funktionelle Charakterisierung von eosinophilen und basophilen Granulozyten

Authors: Ohnmacht, Caspar

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_ZC4YUGLOF44NAZAG5SBPAXYQ7VWZNQBD

The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.

Authors: Maier, Ann-Marie, Huth, Karsten, Alessandrini, Francesca, Henkel, Fiona, Schnautz, Benjamin, Arifovic, Anela, Riols, Fabien, Haid, Mark, Koegler, Anja, Sameith, Katrin, Schmidt-Weber, Carsten B., Esser-von-Bieren, Julia, Ohnmacht, Caspar

Source: Frontiers in Immunology; 2023, p1-14, 14p

Subject Terms: ARYL hydrocarbon receptors, ALVEOLAR macrophages, LIQUID chromatography-mass spectrometry, LIPOXINS, OXYGENASES, HOUSE dust mites, EPITHELIAL cells

Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths

Authors: Ohnmacht, Caspar, Schwartz, Christian, Panzer, Marc, Schiedewitz, Isabell, Naumann, Ronald, Voehringer, David

Source: In Immunity 2010 33(3):364-374

Basophil effector function and homeostasis during helminth infection

Authors: Ohnmacht, Caspar, Voehringer, David ^*

Source: In Blood 19 March 2009 113(12):2816-2825