Establishment of a reproducible and minimally invasive ischemic stroke model in swine

Authors: Carlos Castaño, Marc Melià-Sorolla, Alexia García-Serran, Núria DeGregorio-Rocasolano, Maria Rosa García-Sort, María Hernandez-Pérez, Adrián Valls-Carbó, Osvaldo Pino, Jordi Grífols, Alba Iruela-Sánchez, Alicia Palomar-García, Josep Puig, Octavi Martí-Sistac, Antoni Dávalos, Teresa Gasull

Source: JCI Insight, Vol 8, Iss 8 (2023)

Subject Terms: Neuroscience, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/c21de8f593ff4c549dea247127c76ba2

Targeting Pro-Oxidant Iron with Exogenously Administered Apotransferrin Provides Benefits Associated with Changes in Crucial Cellular Iron Gate Protein TfR in a Model of Intracerebral Hemorrhagic Stroke in Mice

Authors: Alexia García-Serran, Jesús Ordoño, Núria DeGregorio-Rocasolano, Marc Melià-Sorolla, Karla Odendaal, Octavi Martí-Sistac, Teresa Gasull

Source: Antioxidants, Vol 12, Iss 11, p 1945 (2023)

Subject Terms: ischemic stroke, intracerebral hemorrhage, iron, oxidation, apotransferrin, mouse, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/11/1945; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/cc9117fbdea742908262e43c0ddfd323

Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage

Authors: Nuria DeGregorio-Rocasolano, Octavi Martí-Sistac, Jovita Ponce, María Castelló-Ruiz, Mònica Millán, Verónica Guirao, Isaac García-Yébenes, Juan B. Salom, Pedro Ramos-Cabrer, Enrique Alborch, Ignacio Lizasoain, José Castillo, Antoni Dávalos, Teresa Gasull

Source: Redox Biology, Vol 15, Iss C, Pp 143-158 (2018)

Subject Terms: Experimental stroke, Brain damage, Neuroprotection, Apotransferrin, Blood transferrin saturation (TSAT), Reactive oxygen species (ROS), Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231717308017; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/facd8b78a4874d8e865b236e82696fcb

Targeting Pro-Oxidant Iron with Deferoxamine as a Treatment for Ischemic Stroke: Safety and Optimal Dose Selection in a Randomized Clinical Trial

Authors: Mònica Millán, Núria DeGregorio-Rocasolano, Natàlia Pérez de la Ossa, Sílvia Reverté, Joan Costa, Pilar Giner, Yolanda Silva, Tomás Sobrino, Manuel Rodríguez-Yáñez, Florentino Nombela, Francisco Campos, Joaquín Serena, José Vivancos, Octavi Martí-Sistac, Jordi Cortés, Antoni Dávalos, Teresa Gasull

Source: Antioxidants, Vol 10, Iss 8, p 1270 (2021)

Subject Terms: iron, deferoxamine, antioxidant, ferroptosis, neuroprotection, outcome, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/8/1270; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/4d8db7d59d7d4d119ea5ec8697cadfdb

Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation

Authors: Núria DeGregorio-Rocasolano, Verónica Guirao, Jovita Ponce, Marc Melià-Sorolla, Alicia Aliena-Valero, Alexia García-Serran, Juan B. Salom, Antoni Dávalos, Octavi Martí-Sistac, Teresa Gasull

Source: Antioxidants, Vol 9, Iss 12, p 1202 (2020)

Subject Terms: LRRFIP1, DAPK1, neuron, OGD, MCAO, NMDA, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/9/12/1202; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/2fd2397e33f04872804d7f4a2f1658b2

Deciphering the Iron Side of Stroke: Neurodegeneration at the Crossroads Between Iron Dyshomeostasis, Excitotoxicity, and Ferroptosis

Authors: Núria DeGregorio-Rocasolano, Octavi Martí-Sistac, Teresa Gasull

Source: Frontiers in Neuroscience, Vol 13 (2019)

Subject Terms: iron, reactive oxygen species, ferroptosis, stroke, excitotoxicity, iron dyshomeostasis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnins.2019.00085/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/bdab2dc43de64d5780db4fcecd586f2a