Surface salt bridges contribute to the extreme thermal stability of an FN3‐like domain from a thermophilic bacterium

Authors: Boucher, Lauren, Somani, Sandeep, Negron, Christopher, Ma, Wenting, Jacobs, Steven, Chan, Winnie, Malia, Thomas, Obmolova, Galina, Teplyakov, Alexey, Gilliland, Gary L., Luo, Jinquan

Source: Proteins. 90(1):270-281

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147555574.0x000001&indx=1&recIds=ETOCvdc_100147555574.0x000001

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Authors: Laursen, Nick S., Friesen, Robert H. E., Zhu, Xueyong, Jongeneelen, Mandy, Blokland, Sven, Vermond, Jan, van Eijgen, Alida, Tang, Chan, van Diepen, Harry, Obmolova, Galina, van der Neut Kolfschoten, Marijn, Zuijdgeest, David, Straetemans, Roel, Hoffman, Ryan M. B., Nieusmga, Travis, Pallesen, Jesper, Turner, Hannah L., Bernard, Steffen M., Ward, Andrew B., Luo, Jinquan, Poon, Leo L. M., Tretiakova, Anna P., Wilson, James M., Limberis, Maria P., Vogels, Ronald, Brandenburg, Boerries, Kolkman, Joost A., Wilson, Ian A.

Source: Science, 2018 Nov 01. 362(6414), 598-602.

Access URL: https://www.jstor.org/stable/26568495

Inexpensive robotic system for standard and fluorescent imaging of protein crystals

Authors: Handzlik, Dakota, Larson, Eric T., Munschy, Erika, Obmolova, Galina, Collin, Delphine, Craig, Timothy K.

Source: Acta crystallographica.Section F.Structural biology communications. 75(11):673-686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092714127.0x000001&indx=1&recIds=ETOCvdc_100092714127.0x000001

Crystal structure of tissue factor in complex with antibody 10H10 reveals the signaling epitope

Authors: Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Wu, Bingyuan, Zhao, Yonghong, Taudte, Susann, Anderson, G. Mark, Gilliland, Gary L.

Source: In Cellular Signalling August 2017 36:139-144

Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography

Authors: Obmolova, Galina, Teplyakov, Alexey, Malia, Thomas J., Wunderler, Nicole, Kwok, Deborah, Barone, Linda, Sweet, Raymond, Ort, Tatiana, Scully, Michael, Gilliland, Gary L.

Source: In Molecular Immunology March 2017 83:92-99

Structural insights into humanization of anti-tissue factor antibody 10H10

Authors: Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Raghunathan, Gopalan, Martinez, Christian, Fransson, Johan, Edwards, Wilson, Connor, Judith, Husovsky, Matthew, Beck, Heena, Chi, Ellen, Fenton, Sandra, Zhou, Hong, Almagro, Juan Carlos, Gilliland, Gary L.

Source: MAbs. 10(2):269-277

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063115650.0x000001&indx=1&recIds=ETOCvdc_100063115650.0x000001

A coiled conformation of amyloid-β recognized by antibody C706

Authors: Teplyakov, Alexey, Obmolova, Galina, Gilliland, Gary

Source: Alzheimer's research & therapy. 9(1):1-6

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140494533.0x000001&indx=1&recIds=ETOCvdc_100140494533.0x000001

Structural diversity in a human antibody germline library

Authors: Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Luo, Jinquan, Muzammil, Salman, Sweet, Raymond, Almagro, Juan Carlos, Gilliland, Gary L.

Source: MAbs. 8(6):1045-1063

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100033824555.0x000001&indx=1&recIds=ETOCvdc_100033824555.0x000001

IgG2 Fc structure and the dynamic features of the IgG CH2–CH3 interface

Authors: Teplyakov, Alexey, Zhao, Yonghong, Malia, Thomas J., Obmolova, Galina, Gilliland, Gary L.

Source: In Molecular Immunology November 2013 56(1-2):131-139

Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure

Authors: Luo, Jinquan, Obmolova, Galina, Malia, Thomas J., Wu, Sheng-Jiun, Duffy, Karen E., Marion, James D., Bell, Jessica K., Ge, Peng, Zhou, Z. Hong, Teplyakov, Alexey, Zhao, Yonghong, Lamb, Roberta J., Jordan, Jarrat L., San Mateo, Lani R., Sweet, Raymond W., Gilliland, Gary L.

Source: In Journal of Molecular Biology 3 August 2012 421(1):112-124

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888

Authors: Obmolova, Galina, Teplyakov, Alexey, Malia, Thomas J., Grygiel, Tami L.R., Sweet, Raymond, Snyder, Linda A., Gilliland, Gary L.

Source: In Molecular Immunology June 2012 51(2):227-233

Crystal structure of D-serine dehydratase from Escherichia coli

Authors: Urusova, Darya V., Isupov, Michail N., Antonyuk, Svetlana, Kachalova, Galina S., Obmolova, Galina, Vagin, Alexei A., Lebedev, Andrey A., Burenkov, Gleb P., Dauter, Zbigniew, Bartunik, Hans D., Lamzin, Victor S., Melik-Adamyan, William R., Mueller, Thomas D., Schnackerz, Klaus D.

Source: In BBA - Proteins and Proteomics March 2012 1824(3):422-432

The Crystal Structures of Eukaryotic Phosphofructokinases from Baker's Yeast and Rabbit Skeletal Muscle

Authors: Banaszak, Katarzyna, Mechin, Ingrid, Obmolova, Galina, Oldham, Michael, Chang, Simon H., Ruiz, Teresa, Radermacher, Michael, Kopperschläger, Gerhard, Rypniewski, Wojciech

Source: In Journal of Molecular Biology 25 March 2011 407(2):284-297

Expression, refolding and purification of a human interleukin-17A variant

Authors: Wu, Bingyuan, Nemeth, Jennifer F., Janecki, Dariusz J., Jones, Brian, Obmolova, Galina, Malia, Thomas J., Baker, Audrey, Bethea, Deidra, Elloso, M. Merle, Naso, Michael, Taudte, Susann

Source: In Cytokine January 2011 53(1):107-114

Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab

Authors: Luo, Jinquan, Wu, Sheng-Jiun, Lacy, Eilyn R., Orlovsky, Yevgeniya, Baker, Audrey, Teplyakov, Alexey, Obmolova, Galina, Heavner, George A., Richter, Hans-Thomas, Benson, Jacqueline

Source: In Journal of Molecular Biology 8 October 2010 402(5):797-812

Coevolution of Antibody Stability and Vκ CDR-L3 Canonical Structure

Authors: Luo, Jinquan, Obmolova, Galina, Huang, Alice, Strake, Brandy, Teplyakov, Alexey, Malia, Thomas, Muzammil, Salman, Zhao, Yonghong, Gilliland, Gary L., Feng, Yiqing

Source: In Journal of Molecular Biology 2010 402(4):708-719

Human Framework Adaptation of a Mouse Anti-Human IL-13 Antibody

Authors: Fransson, Johan ^†, Teplyakov, Alexey ^†, Raghunathan, Gopalan ^†, Chi, Ellen, Cordier, Wendy, Dinh, Thai, Feng, Yiqing, Giles-Komar, Jill, Gilliland, Gary, Lollo, Bridget, Malia, Thomas J., Nishioka, Walter, Obmolova, Galina, Zhao, Shanrong, Zhao, Yonghong, Swanson, Ronald V., Almagro, Juan C.

Source: In Journal of Molecular Biology 2010 398(2):214-231

Epitope Mapping of Anti-Interleukin-13 Neutralizing Antibody CNTO607

Authors: Teplyakov, Alexey, Obmolova, Galina, Wu, Sheng-Jiun, Luo, Jinquan, Kang, James, O'Neil, Karyn, Gilliland, Gary L.

Source: In Journal of Molecular Biology 29 May 2009 389(1):115-123

Two routes for production and purification of Fab fragments in biopharmaceutical discovery research: Papain digestion of mAb and transient expression in mammalian cells

Authors: Zhao, Yonghong, Gutshall, Lester, Jiang, Haiyan, Baker, Audrey, Beil, Eric, Obmolova, Galina, Carton, Jill, Taudte, Susann, Amegadzie, Bernard

Source: In Protein Expression and Purification 2009 67(2):182-189

IL-17A antibodies