NEW APPROACH FOR ASSURING HIGHER QUALITY OF CALCIUM OROTATE BY ESTIMATING OROTIC ACID CONTENT USING STABILITY INDICATING RP-HPLC METHOD.

Authors: Jalundhwala, Forum J.^1,2 forum.jalundhwala@gmail.com, Londhe, Vaishali Y.¹, Shah, Bharat S.²

Source: Indian Drugs. Aug2024, Vol. 61 Issue 8, p54-60. 7p.

Subject Terms: *OROTIC acid, *POTASSIUM phosphates, *QUALITY control, *HIGH performance liquid chromatography, *CALCIUM salts

A Facile Fluorometric Assay of Orotate Phosphoribosyltransferase Activity Using a Selective Fluorogenic Reaction for Orotic Acid.

Authors: Shibata, Takayuki¹ (AUTHOR) tshibata@gunma-u.ac.jp, Narita, Tomohiro² (AUTHOR), Suto, Yutaka³ (AUTHOR), Yasmin, Hasina⁴ (AUTHOR), Kabashima, Tsutomu⁵ (AUTHOR)

Source: Sensors (14248220). Mar2023, Vol. 23 Issue 5, p2507. 9p.

Subject Terms: *OROTIC acid, *RADIOMETRIC methods, *BIOSYNTHESIS, *HELA cells, *DRUG development, *URIDINE

Metabolomic Analyses to Identify Candidate Biomarkers of Cystinosis.

Authors: Nemutlu, Emirhan¹ (AUTHOR), Ozaltin, Fatih^2,3 (AUTHOR), Yabanoglu-Ciftci, Samiye⁴ (AUTHOR), Gulhan, Bora² (AUTHOR), Eylem, Cemil Can¹ (AUTHOR), Baysal, İpek⁵ (AUTHOR), Gök-Topak, Elif Damla^1,6 (AUTHOR), Ulubayram, Kezban⁷ (AUTHOR), Sezerman, Osman Ugur⁸ (AUTHOR), Ucar, Gulberk⁴ (AUTHOR), Kır, Sedef¹ (AUTHOR), Topaloglu, Rezan² (AUTHOR) rezantopaloglu@hacettepe.edu.tr

Source: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 3, p2603. 14p.

Subject Terms: *OROTIC acid, *PYRUVIC acid, *DECANOIC acid, *METABOLOMICS, *QUINIC acid, *TOXINS, *GLUCURONIC acid, *ACETIC acid, *CREATININE

Neonatal-onset of Ornithine Transcarbamylase Deficiency: A Case of Severe Hyperammonaemia.

Authors: Ariffin, Afiqah^1,2, Samsudin, Intan Nureslyna¹ intanlyna@upm.edu.my, Thambiah, Subashini C.¹, Lai Yin Ye¹, Tengku Yazid, Tengku Norita²

Source: Malaysian Journal of Medicine & Health Sciences. 2024 Supplement, Vol. 20, p81-83. 3p.

Subject Terms: *AMINO acid analysis, *OROTIC acid, *INBORN errors of metabolism, *CEREBRAL edema, *ORGANIC acids

Terahertz Spectroscopy and Density Functional Theory Analysis of the Molecular Interactions in Crystalline Orotic Acid Monohydrate.

Authors: Zheng, Zh.¹ (AUTHOR) zhengzhuanp@xupt.edu.cn, Zeng, F.¹ (AUTHOR), Zhi, Y.¹ (AUTHOR), Zhu, L.¹ (AUTHOR)

Source: Journal of Applied Spectroscopy. May2022, Vol. 89 Issue 2, p316-321. 6p.

Subject Terms: *OROTIC acid, *DENSITY functional theory, *MOLECULAR theory, *TERAHERTZ spectroscopy, *FUNCTIONAL analysis, *INTERMOLECULAR forces

New drug–drug and drug–nutraceutical salts of anti-emetic drug domperidone: structural and physicochemical aspects of new salts.

Authors: Nechipadappu, Sunil Kumar^1,2 (AUTHOR) nsunilkumar@iict.res.in, Swain, Debasish^2,3 (AUTHOR) debasish@iict.res.in

Source: CrystEngComm. 2/21/2024, Vol. 26 Issue 7, p926-942. 17p.

Subject Terms: *NIACIN, *OROTIC acid, *DOMPERIDONE, *SALICYLIC acid, *SALT, *DRUG solubility, *ASPIRIN

Effect of Subclinical Mastitis on Fibrinogen, Orotic Acid and Some Enzymes in the Milk of Dairy Cows.

Authors: Sahu, Suresh¹, Maiti, Sushil Kumar² sushilkumarmaiti123@gmail.com, Raghuvanshi, Pavan Divan Singh²

Source: Indian Journal of Veterinary Sciences & Biotechnology. Oct-Dec2020, Vol. 16 Issue 2/4, p17-20. 4p.

Subject Terms: *GOAT milk, *OROTIC acid, *DAIRY cattle, *MASTITIS, *ACUTE phase proteins, *FIBRINOGEN, *LACTATE dehydrogenase

Geographic Terms: CALIFORNIA

İdrarda Orotik Asit'in Temassız İletkenlik Dedektörü Kullanılarak Kapiler Elektroforez Yöntemi İle Hızlı Tayini.

Alternate Title: Rapid Determination Of Orotic Acid Level In Urine By Capillary Electrophoresis Coupled With Contactless Conductivity Detection.

Authors: CANSEVER, Mehmet ġerif¹ mscansever@nku.edu.tr, ÖZTEKĠN, Nevin², ADIMCILAR, Veselina², ZÜBARĠOĞLU, Tanyel³, KIYKIM, Ertuğrul⁴, AKTUĞLU ZEYBEK, AyĢe Çiğdem⁴

Source: Suleyman Demirel University Faculty of Arts & Science Journal of Science / Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi. 2020, Vol. 15 Issue 2, p194-202. 9p.

Subject Terms: *OROTIC acid, *ELECTROLYTE solutions, *CETYLTRIMETHYLAMMONIUM bromide, *DETECTION limit, *METABOLIC disorders, *UREA

Pyrimidine Nucleotide Biosynthesis and Regulation in Pseudomonas lemonnieri.

Authors: Bodampati, Swapna, West, Thomas P.

Source: Current Microbiology; Jan2025, Vol. 82 Issue 1, p1-8, 8p

Subject Terms: CHEMICAL mutagenesis, PSEUDOMONAS fluorescens, OROTIC acid, PYRIMIDINES, URACIL

Green microalga Chromochloris zofingiensis conserves substrate uptake pattern but changes their metabolic uses across trophic transition.

Authors: Hu, Yuntao, Kim, Nakian, Roth, Melissa S., Louie, Katherine B., Kosina, Suzanne M., Upadhyaya, Shivani, Jeffers, Tim L., Jordan, Jacob S., Bowen, Benjamin P., Niyogi, Krishna K., Northen, Trent R.

Source: Frontiers in Microbiology; 2024, p1-11, 11p

Subject Terms: OROTIC acid, BIOCHEMICAL substrates, INDUSTRIAL capacity, GREEN algae, ARGININE

Isolated Hyperammonemia Presenting as Postpartum Coma in a Parturient with Undiagnosed Urea Cycle Disorder: A Case Report.

Authors: Trivedi, Saurabh, Dhurwe, Ritika, Karna, Sunaina T., Sharma, Jai P.

Source: Indian Journal of Critical Care Case Reports (IJCCR); Nov/Dec2024, Vol. 3 Issue 6, p165-168, 4p

Subject Terms: ENZYME deficiency, TRANSITION to adulthood, OROTIC acid, CESAREAN section, HYPERAMMONEMIA, UREA

Structures and luminescence properties of one co‐edge bi‐rhomboid [Zn6] based 1D stair‐stepping polymer and one quasi‐linear tetra‐nuclear [Cd4] cluster with orotic acid.

Authors: Zhao, Bing¹ (AUTHOR) zhaobing@zua.edu.cn

Source: Zeitschrift für Anorganische und Allgemeine Chemie. 12/13/2023, Vol. 649 Issue 24, p1-5. 5p.

Subject Terms: *COORDINATION polymers, *OROTIC acid, *LUMINESCENCE, *POLYMERS, *X-ray diffraction, *CD4 antigen

The Strange Case of Orotic Acid: The Different Expression of Pyrimidines Biosynthesis in Healthy Males and Females.

Authors: Chiara, Francesco¹ (AUTHOR) 336124@edu.unito.it, Allegra, Sarah¹ (AUTHOR) giuliana.abbadessa@unito.it, Mula, Jacopo² (AUTHOR) jacopo.mula@unito.it, Puccinelli, Maria Paola³ (AUTHOR) mpuccinelli@cittadellasalute.to.it, Abbadessa, Giuliana¹ (AUTHOR) silvia.defrancia@unito.it, Mengozzi, Giulio³ (AUTHOR) gmengozzi@cittadellasalute.to.it, De Francia, Silvia¹ (AUTHOR)

Source: Journal of Personalized Medicine. Oct2023, Vol. 13 Issue 10, p1443. 14p.

Subject Terms: *OROTIC acid, *BIOSYNTHESIS, *CLINICAL chemistry, *PYRIMIDINES, *GENETIC disorders

Ammonia and coma - a case report of late onset hemizygous ornithine carbamyltransferase deficiency in 68-year-old female.

Authors: Marquetand, Justus^1,2 (AUTHOR) justus.marquetand@med.uni-tuebingen.de, Freisinger, Peter³ (AUTHOR), Lindig, Tobias⁴ (AUTHOR), Euler, Sebastian² (AUTHOR), Gasser, Michael⁵ (AUTHOR), Overkamp, Dietrich⁶ (AUTHOR)

Source: BMC Neurology. 4/6/2020, Vol. 20 Issue 1, p1-5. 5p. 2 Graphs.

Subject Terms: *OROTIC acid, *NEWBORN infants, *COMA, *AMMONIA, *AMINO acids, *METABOLIC disorders, *AMINO acid metabolism disorders

The pharmacokinetics of mycophenolic acid in rats with orotic acid induced nonalcoholic fatty liver disease.

Authors: Subali, Dionysius^1,2, Kwon, Mi Hye^1,2, Bang, Won Seok², Kang, Hee Eun² kanghe@catholic.ac.kr

Source: Canadian Journal of Physiology & Pharmacology. 2020, Vol. 98 Issue 3, p169-176. 8p.

Subject Terms: *FATTY liver, *OROTIC acid, *MYCOPHENOLIC acid, *MULTIDRUG resistance-associated proteins, *RAT control

Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro.

Authors: Funk, Ryan S.¹ (AUTHOR) ryanfunk@kumc.edu, Singh, Rakesh K.¹ (AUTHOR), Becker, Mara L.² (AUTHOR)

Source: CTS: Clinical & Translational Science. Jan2020, Vol. 13 Issue 1, p137-146. 10p.

Subject Terms: *AMINO acid metabolism, *OROTIC acid, *METHOTREXATE, *AUTOIMMUNE disease treatment, *BIOLOGICAL tags, *GALACTOSE, *CELL growth, *FRUCTOSE

Design and synthesis of a novel fluorescent probe, EuIII-dtpa-bis(adenine), and application for the detection of orotic acid in urine.

Authors: Yu, Zhiyue¹, Jia, Haishuang^1,2, Li, Na^2,3, Liu, Wenfang¹, Wang, Jun¹, wangjun888tg@126.com, Song, Youtao^2,3

Source: Canadian Journal of Chemistry; 2019, Vol. 97 Issue 11, p763-771, 9p

Synthesis, Characterization, and Anti-Diabetic Therapeutic Activity of New Vanadyl(II) Complexes with Orotic Acid and Different Amino Acids Mixed Ligands.

Authors: Al-Wasidi, A. S.¹, Al-Jafshar, N. M.¹, Al-Anazi, A. M.¹, Refat, M. S.^2,3 msrefat@yahoo.com, Ismail, L. A.³, Al-Omar, M. A.⁴, Naglah, A. M.^4,5, Kalmouch, Atef⁵

Source: Russian Journal of General Chemistry. Oct2019, Vol. 89 Issue 10, p2121-2128. 8p.

Subject Terms: *OROTIC acid, *AMINO acids, *LIGANDS (Chemistry), *THREONINE, *INSULIN synthesis, *BLOOD sugar, *PHENYLALANINE

Content of orotic acid and selected bioactive compounds in ovine milk during lamb rearing.

Authors: Wojtak, W., Białek, M., Białek, A., Molik, E., Czauderna, M.

Source: Journal of Animal & Feed Sciences; 2024, Vol. 33 Issue 4, p547-561, 15p

Subject Terms: SHEEP milk, OROTIC acid, MULTIVARIATE analysis, NUTRITIONAL requirements, EICOSAPENTAENOIC acid, LACTATION

Comparison of the effects of two soy waste-based culture media on the technological properties of Lacticaseibacillus paracasei 90 as adjunct culture in miniature Cremoso cheese.

Authors: Beret, M. Victoria, Bergamini, Carina V., Giménez, Paula, Ale, Elisa C., Wolf, I. Verónica, Peralta, Guillermo H.

Source: Journal of Dairy Research; Aug2024, Vol. 91 Issue 3, p358-366, 9p

Subject Terms: CHEESEMAKING, PYRUVIC acid, HIPPURIC acid, OROTIC acid, LACTIC acid, GALACTOSE