O-GlcNAc glycans in the mammalian extracellular environment

Authors: Tsukamoto, Yohei ^{a, b}, Okajima, Tetsuya ^{a, b, ⁎}

Source: In Carbohydrate Research March 2025 549

Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance

Authors: Hashimoto, Noboru ^{1, 2}, Ito, Shizuka ¹, Harazono, Akira ³, Tsuchida, Akiko ⁴, Mouri, Yasuhiro ⁵, Yamamoto, Akihito ², Okajima, Tetsuya ¹, Ohmi, Yuhsuke ⁶, Furukawa, Keiko ⁷, Kudo, Yasusei ⁵, Kawasaki, Nana ⁸, Furukawa, Koichi ^{1, 7, 9, ∗}

Source: In iScience 15 November 2024 27(11)

The N-acetylglucosaminyltransferase Radical fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants

Authors: Suzuki, Shodai, Mashiko, Taiki, Tsukamoto, Yohei, Oya, Miyu, Kotani, Yuki, Okawara, Saki, Matsumoto, Takemi, Mizue, Yuki, Takeuchi, Hideyuki, Okajima, Tetsuya, Itoh, Motoyuki

Source: In Journal of Biological Chemistry October 2024 300(10)

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

Authors: Irvine Kenneth D, Matsuda Tsukasa, Reddy BVVG, Okajima Tetsuya

Source: BMC Biology, Vol 6, Iss 1, p 1 (2008)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.biomedcentral.com/1741-7007/6/1; https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/35a0d9d9b2444346ab249d486fb52276

Evidence that only EWS among the FET proteins acquires a low partitioning property for the hyperosmotic stress response by O-GlcNAc glycosylation on its low-complexity domain

Authors: Kakuo, Manami, Horii, Takeshi, Tonomura, Naoto, Sato, Runa, Ogawa, Mitsutaka, Okajima, Tetsuya, Kamemura, Kazuo

Source: In Experimental Cell Research 1 March 2023 424(1)

Secretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation

Authors: Zhang, Ailing, Tsukamoto, Yohei, Takeuchi, Hideyuki, Nishiwaki, Kimitoshi, Tashima, Yuko, Okajima, Tetsuya

Source: In Analytical Biochemistry 1 November 2022 656

Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1

Authors: Tsukamoto, Yohei, Ogawa, Mitsutaka, Yogi, Kentarou, Tashima, Yuko, Takeuchi, Hideyuki, Okajima, Tetsuya

Source: Glycobiology. 32(7):616-628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155647738.0x000001&indx=1&recIds=ETOCvdc_100155647738.0x000001

Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine

Authors: Hashiguchi, Hiroki, Tsukamoto, Yohei, Ogawa, Mitsutaka, Tashima, Yuko, Takeuchi, Hideyuki, Nakamura, Masanao, Kawashima, Hiroki, Fujishiro, Mitsuhiro, Okajima, Tetsuya

Source: In Archives of Biochemistry and Biophysics 30 November 2020 695

N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization

Authors: Alam, Sayad Md. Didarul, Tsukamoto, Yohei, Ogawa, Mitsutaka, Senoo, Yuya, Ikeda, Kazutaka, Tashima, Yuko, Takeuchi, Hideyuki, Okajima, Tetsuya ^*

Source: In Journal of Biological Chemistry 19 June 2020 295(25):8560-8574

The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid–binding lectin SIGLEC7 on the cell surface

Alternate Title: Ceramide structures involved in the recognition of Siglec-7 (English)

Authors: Hashimoto, Noboru, Ito, Shizuka, Tsuchida, Akiko, Bhuiyan, Robiul H., Okajima, Tetsuya, Yamamoto, Akihito, Furukawa, Keiko, Ohmi, Yuhsuke, Furukawa, Koichi

Source: In Journal of Biological Chemistry July 2019 294(28):10833-10845

Structure and function of extracellular O-GlcNAc

Authors: Ogawa, Mitsutaka, Okajima, Tetsuya

Source: In Current Opinion in Structural Biology June 2019 56:72-77

Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking

Authors: Ogawa, Mitsutaka, Tashima, Yuko, Sakaguchi, Yamato, Takeuchi, Hideyuki, Okajima, Tetsuya

Source: Biochemical and biophysical research communications. 526(1):184-190

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114272000.0x000001&indx=1&recIds=ETOCvdc_100114272000.0x000001

Recent topics on structure and function of extracellular O-GlcNAc

Authors: Tashima, Yuko, Okajima, Tetsuya

Source: Seikagaku. 92(6):833-837

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626054479&indx=1&recIds=ETOCRN626054479

Loss of Enzyme Activity in Mutated B4GALNT1 Gene Products in Patients with Hereditary Spastic Paraplegia Results in Relatively Mild Neurological Disorders: Similarity with Phenotypes of B4galnt1 Knockout Mice

Authors: Bhuiyan, Robiul H., Ohmi, Yuhsuke, Ohkawa, Yuki, Zhang, Pu, Takano, Maiko, Hashimoto, Noboru, Okajima, Tetsuya, Furukawa, Keiko, Furukawa, Koichi

Source: In Neuroscience 15 January 2019 397:94-106

The Human Glycome Atlas project for cataloging all glycan-related omics data in human.

Authors: Aoki-Kinoshita, Kiyoko F, Akune-Taylor, Yukie, Ando, Hiromune, Angata, Kiyohiko, Fujita, Morihisa, Furukawa, Jun-ichi, Kaji, Hiroyuki, Kato, Koichi, Kitajima, Ken, Kizuka, Yasuhiko, Matsui, Yusuke, Nakajima, Kazuki, Nishihara, Shoko, Okajima, Tetsuya, Sakamoto, Kazuma, Sato, Chihiro, Thaysen-Andersen, Morten, Togayachi, Akira, Yagi, Hirokazu, Zappa, Achille

Source: Glycobiology; Nov2024, Vol. 34 Issue 11, p1-3, 3p

Subject Terms: FIVE year plans, HIGHER education research, DATABASES, GLYCANS, BLOOD sampling

Chaperone Activity of Protein O-Fucosyltransferase 1 Promotes Notch Receptor Folding

Authors: Okajima, Tetsuya, Xu, Aiguo, Lei, Liang, Irvine, Kenneth D.

Source: Science, 2005 Mar 01. 307(5715), 1599-1603.

Access URL: https://www.jstor.org/stable/3841770

Inhibitory machinery for the functional dystroglycan glycosylation.

Authors: Kondo, Yuji^1,2 (AUTHOR), Okajima, Tetsuya^1,2 (AUTHOR) tokajima@med.nagoya-u.ac.jp

Source: Journal of Biochemistry. May2023, Vol. 17 Issue 5, p333-335. 3p.

Subject Terms: *DYSTROGLYCAN, *GLYCOSYLATION, *MEMBRANE proteins, *MUSCLE strength, *CELL membranes, *GLYCANS, *RYANODINE

Significant Roles of Notch O -Glycosylation in Cancer.

Authors: Wang, Weiwei¹ (AUTHOR) oubibi82@yahoo.co.jp, Okajima, Tetsuya^1,2 (AUTHOR) tokajima@med.nagoya-u.ac.jp, Takeuchi, Hideyuki^1,3 (AUTHOR) htakeuchi@u-shizuoka-ken.ac.jp

Source: Molecules. Mar2022, Vol. 27 Issue 6, p1783. 19p.

Subject Terms: *NOTCH genes, *HEMATOLOGIC malignancies, *ACUTE myeloid leukemia, *LYMPHOBLASTIC leukemia, *TRAFFIC signs & signals, *CELL differentiation

Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans

Authors: Tsukamoto, Yohei, Tsukamoto, Natsumi, Saiki, Wataru, Tashima, Yuko, Furukawa, Jun-ichi, Kizuka, Yasuhiko, Narimatsu, Yoshiki, Clausen, Henrik, Takeuchi, Hideyuki, Okajima, Tetsuya

Source: In Biochemical and Biophysical Research Communications 9 April 2024 703

Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells

Authors: Kaneko, Kei, Ohkawa, Yuki, Hashimoto, Noboru, Ohmi, Yuhsuke, Kotani, Norihiro, Honke, Koichi, Ogawa, Mitsutaka, Okajima, Tetsuya, Furukawa, Keiko, Furukawa, Koichi

Source: In Journal of Biological Chemistry 5 August 2016 291(32):16630-16643