Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa

Authors: Branchett, William J, Saraiva, Margarida, O’Garra, Anne

Source: In Current Opinion in Immunology December 2024 91

Interferon-gamma release assay conversion after Mycobacterium tuberculosis exposure specifically associates with greater risk of progression to tuberculosis: A prospective cohort study in Leicester, UK

Authors: Kim, Jee Whang, Nazareth, Joshua, Lee, Joanne, Patel, Hemu, Woltmann, Gerrit, Verma, Raman, O'Garra, Anne, Haldar, Pranabashis

Source: In International Journal of Infectious Diseases April 2024 141

Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure

Authors: Branchett, William J., Cook, James, Oliver, Robert A., Bruno, Nicoletta, Walker, Simone A., Stölting, Helen, Mack, Matthias, O’Garra, Anne, Saglani, Sejal, Lloyd, Clare M.

Source: In The Journal of Allergy and Clinical Immunology May 2021 147(5):1892-1906

Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy

Authors: Aitken, Jim, Allen, Zoe, Ambler, Rachel, Ambrose, Karen, Ashton, Emma, Avola, Alida, Balakrishnan, Samutheswari, Barns-Jenkins, Caitlin, Barr, Genevieve, Barrell, Sam, Basu, Souradeep, Beale, Rupert, Beesley, Clare, Bhardwaj, Nisha, Bibi, Shahnaz, Bineva-Todd, Ganka, Biswas, Dhruva, Blackman, Michael J., Bonnet, Dominique, Bowker, Faye, Broncel, Malgorzata, Brooks, Claire, Buck, Michael D., Buckton, Andrew, Budd, Timothy, Burrell, Alana, Busby, Louise, Bussi, Claudio, Butterworth, Simon, Byott, Matthew, Byrne, Fiona, Byrne, Richard, Caidan, Simon, Campbell, Joanna, Canton, Johnathan, Cardoso, Ana, Carter, Nick, Carvalho, Luiz, Carzaniga, Raffaella, Chandler, Natalie, Chen, Qu, Cherepanov, Peter, Churchward, Laura, Clark, Graham, Clayton, Bobbi, Cobolli Gigli, Clementina, Collins, Zena, Cottrell, Sally, Crawford, Margaret, Cubitt, Laura, Cullup, Tom, Davies, Heledd, Davis, Patrick, Davison, Dara, Dearing, Vicky, Debaisieux, Solene, Diaz-Romero, Monica, Dibbs, Alison, Diring, 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Source: In Epilepsy & Behavior February 2021 115

A T cell–myeloid IL-10 axis regulates pathogenic IFN-γ–dependent immunity in a mouse model of type 2–low asthma

Authors: Branchett, William J., Stölting, Helen, Oliver, Robert A., Walker, Simone A., Puttur, Franz, Gregory, Lisa G., Gabryšová, Leona, Wilson, Mark S., O'Garra, Anne, Lloyd, Clare M.

Source: In The Journal of Allergy and Clinical Immunology February 2020 145(2):666-678

IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation

Authors: Ouyang, Wenjun, O’Garra, Anne

Source: In Immunity 16 April 2019 50(4):871-891

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

Authors: Singhania, Akul, Graham, Christine, Gabryšová, Leona, Moreira-Teixeira, Lúcia, Stavropoulos, Evangelos, Pitt, Jonathan, Chakravarty, Probir, Warnatsch, Annika, Branchett, William, Conejero, Laura, Lin, Jing-Wen, Davidson, Sophia, Wilson, Mark, Bancroft, Gregory, Langhorne, Jean, Frickel, Eva, Sesay, Abdul, Priestnall, Simon, Herbert, Eleanor, Ioannou, Marianna, Wang, Qian, Humphreys, Ian, Dodd, Jonathan, Openshaw, Peter, Mayer-Barber, Katrin, Jankovic, Dragana, Sher, Alan, Lloyd, Clare, Baldwin, Nicole, Chaussabel, Damien, Papayannopoulos, Venizelos, Wack, Andreas, Banchereau, Jacques, Pascual, Virginia, O'Garra, Anne

Source: Nature communications. 10(1):1-21

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182784958.0x000001&indx=1&recIds=ETOCvdc_100182784958.0x000001

Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis

Authors: Esmail, Hanif, Lai, Rachel P., Lesosky, Maia, Wilkinson, Katalin A., Graham, Christine M., Horswell, Stuart, Coussens, Anna K., Barry, Clifton E., O’Garra, Anne, Wilkinson, Robert J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Jan . 115(5), E964-E973.

Access URL: https://www.jstor.org/stable/26507300

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

Authors: Singhania, Akul, Verma, Raman, Graham, Christine, Lee, Jo, Tran, Trang, Richardson, Matthew, Lecine, Patrick, Leissner, Philippe, Berry, Matthew, Wilkinson, Robert, Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O'Garra, Anne

Source: Nature communications. 9(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170090201.0x000001&indx=1&recIds=ETOCvdc_100170090201.0x000001

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza

Authors: Dunning, Jake, Blankley, Simon, Hoang, Long, Cox, Mike, Graham, Christine, James, Philip, Bloom, Chloe, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen, Moffatt, Miriam, O'Garra, Anne, Openshaw, Peter

Source: Nature immunology. 19(6):625-635

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171359448.0x000001&indx=1&recIds=ETOCvdc_100171359448.0x000001

C-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

Authors: Gabryšová, Leona, Alvarez-Martinez, Marisol, Luisier, Raphaëlle, Cox, Luke, Sodenkamp, Jan, Hosking, Caroline, Pérez-Mazliah, Damián, Whicher, Charlotte, Kannan, Yashaswini, Potempa, Krzysztof, Wu, Xuemei, Bhaw, Leena, Wende, Hagen, Sieweke, Michael, Elgar, Greg, Wilson, Mark, Briscoe, James, Metzis, Vicki, Langhorne, Jean, Luscombe, Nicholas, O'Garra, Anne

Source: Nature immunology. 19(5):497-507

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171359726.0x000001&indx=1&recIds=ETOCvdc_100171359726.0x000001

Inflammasome Activation Underlying Central Nervous System Deterioration in HIV-Associated Tuberculosis

Authors: Marais, Suzaan, Lai, Rachel P. J., Wilkinson, Katalin A., Meintjes, Graeme, O'Garra, Anne, Wilkinson, Robert J.

Source: The Journal of Infectious Diseases, 2017 Mar 01. 215(5), 677-686.

Access URL: http://www.jstor.org/stable/26167043

The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis

Authors: Blankley, Simon, Berry, Matthew Paul Reddoch, Graham, Christine M., Bloom, Chloe I., Lipman, Marc, O'Garra, Anne

Source: Philosophical Transactions: Biological Sciences, 2014 Jun . 369(1645), 1-9.

Access URL: https://www.jstor.org/stable/24499034

Preface: The science of infectious diseases

Authors: Dye, Christopher, O'Garra, Anne

Source: Philosophical Transactions: Biological Sciences, 2014 Jun . 369(1645), 1-2.

Access URL: https://www.jstor.org/stable/24499032

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis

Authors: Alvarez-Martinez, Marisol, Cox, Luke S., Pearson, Claire F., Branchett, William J., Chakravarty, Probir, Wu, Xuemei, Slawinski, Hubert, Al-Dibouni, Alaa, Samelis, Vasileios A., Gabryšová, Leona, Priestnall, Simon L., Suárez-Bonnet, Alejandro, Mikolajczak, Anna, Briscoe, James, Powrie, Fiona, O’Garra, Anne

Source: Nature Immunology; 20240101, Issue: Preprints p1-16, 16p

Systems approaches to studying the immune response in tuberculosis

Authors: Berry, Matthew Paul Reddoch, Blankley, Simon, Graham, Christine Marian, Bloom, Chloe I, O’Garra, Anne

Source: In Current Opinion in Immunology October 2013 25(5):579-587

Vaccination against tuberculosis: How can we better BCG?

Authors: Pitt, Jonathan M., Blankley, Simon, McShane, Helen, O'Garra, Anne

Source: In Microbial Pathogenesis May 2013 58:2-16

Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis

Authors: Moreira-Teixeira, Lúcia, Stimpson, Philippa J., Stavropoulos, Evangelos, Hadebe, Sabelo, Chakravarty, Probir, Ioannou, Marianna, Aramburu, Iker Valle, Herbert, Eleanor, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Sousa, Jeremy, Fonseca, Kaori L., Wang, Qian, Vashakidze, Sergo, Rodríguez-Martínez, Paula, Vilaplana, Cristina, Saraiva, Margarida, Papayannopoulos, Venizelos, O'Garra, Anne

Source: Nature communications. 11(1)

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Influenza A Virus Impairs Control of Mycobacterium tuberculosis Coinfection Through a Type I Interferon Receptor—Dependent Pathway

Authors: Redford, Paul S., Mayer-Barber, Katrin D., McNab, Finlay W., Stavropoulos, Evangelos, Wack, Andreas, Sher, Alan, O'Garra, Anne

Source: The Journal of Infectious Diseases, 2014 Jan . 209(2), 270-274.

Access URL: http://www.jstor.org/stable/43707957

Neutrophils in tuberculosis: friend or foe?

Authors: Lowe, David M., Redford, Paul S., Wilkinson, Robert J., O’Garra, Anne, Martineau, Adrian R.

Source: In Trends in Immunology 2012 33(1):14-25