Increasing protein stability by inferring substitution effects from high-throughput experiments

Authors: Norrild, Rasmus Krogh, Johansson, Kristoffer Enøe, O’Shea, Charlotte, Morth, Jens Preben, Lindorff-Larsen, Kresten, Winther, Jakob Rahr

Source: In Cell Reports Methods 21 November 2022 2(11)

Allovalent scavenging of activation domains in the transcription factor ANAC013 gears transcriptional regulation.

Authors: Delaforge, Elise, Due, Amanda D, Theisen, Frederik Friis, Morffy, Nicolas, O'Shea, Charlotte, Blackledge, Martin, Strader, Lucia C, Skriver, Karen, Kragelund, Birthe B

Source: Nucleic Acids Research; 2/28/2025, Vol. 53 Issue 4, p1-15, 15p

The promoters of OsGLP genes exhibited differentially methylated sites under drought and salt stress in rice cultivars.

Authors: Anum, Jazba¹ (AUTHOR), O'Shea, Charlotte² (AUTHOR), Skriver, Karen² (AUTHOR), Saeed, Muhammad¹ (AUTHOR), Hyder, Muhammad Zeeshan¹ (AUTHOR), Farrakh, Sumaira¹ (AUTHOR), Yasmin, Tayyaba¹ (AUTHOR) tayyaba_yasmin@comsats.edu.pk

Source: Euphytica. Apr2023, Vol. 219 Issue 4, p1-15. 15p.

Subject Terms: *DROUGHTS, *RICE, *PROMOTERS (Genetics), *CULTIVARS, *PLANT genes, *PLANT defenses, *ABIOTIC stress

Structure of Radical-Induced Cell Death1 Hub Domain Reveals a Common αα-Scaffold for Disorder in Transcriptional Networks

Authors: Bugge, Katrine, Staby, Lasse, Kemplen, Katherine R., O'Shea, Charlotte, Bendsen, Sidsel K., Jensen, Mikael K., Olsen, Johan G., Skriver, Karen, Kragelund, Birthe B.

Source: In Structure 1 May 2018 26(5):734-746

Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1

Authors: O'Shea, Charlotte, Staby, Lasse, Bendsen, Sidsel Krogh, Tidemand, Frederik Grønbæk, Redsted, Andreas, Willemoës, Martin, Kragelund, Birthe B., Skriver, Karen

Source: In Journal of Biological Chemistry 13 January 2017 292(2):512-527

Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants.

Authors: Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie, Leurs, Yannick H. A., Morffy, Nicholas, Strader, Lucia C., O’Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe B., Skriver, Karen

Source: Nature Communications; 1/18/2024, Vol. 15 Issue 1, p1-13, 13p

Barley plants over-expressing the NAC transcription factor gene HvNAC005 show stunting and delay in development combined with early senescence

Authors: Christiansen, Michael W., Matthewman, Colette, Podzimska-Sroka, Dagmara, O’Shea, Charlotte, Lindemose, Søren, Møllegaard, Niels Erik, Holme, Inger B., Hebelstrup, Kim, Skriver, Karen, Gregersen, Per L.

Source: Journal of Experimental Botany, 2016 Jan 01. 67(17), 5259-5273.

Access URL: https://www.jstor.org/stable/26391343

Gentamicin Binds to the Megalin Receptor as a Competitive Inhibitor Using the Common Ligand Binding Motif of Complement Type Repeats: INSIGHT FROM THE NMR STRUCTURE OF THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE AND IN COMPLEX WITH GENTAMICIN

Authors: Dagil, Robert, O'Shea, Charlotte, Nykjær, Anders, Bonvin, Alexandre M.J.J., Kragelund, Birthe B.

Source: In Journal of Biological Chemistry February 2013 288(6):4424-4435

The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor

Authors: Dagil, Robert, Knudsen, Maiken J., Olsen, Johan G., O'Shea, Charlotte, Franzmann, Magnus, Goffin, Vincent, Teilum, Kaare, Breinholt, Jens, Kragelund, Birthe B.

Source: In Structure 8 February 2012 20(2):270-282

Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome

Authors: Christensen, Lise Friis, Staby, Lasse, Bugge, Katrine, O'Shea, Charlotte, Kragelund, Birthe B., Skriver, Karen

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131399408.0x000001&indx=1&recIds=ETOCvdc_100131399408.0x000001

Binding Site Structure of One LRP–RAP Complex:Implications for a Common Ligand–Receptor Binding Motif

Authors: Jensen, Gitte A., Andersen, Olav M., Bonvin, Alexandre M.J.J., Bjerrum-Bohr, Ida, Etzerodt, Michael, Thøgersen, Hans C., O'Shea, Charlotte, Poulsen, Flemming M., Kragelund, Birthe B.

Source: In Journal of Molecular Biology 2006 362(4):700-716

Germin like protein genes exhibit modular expression during salt and drought stress in elite rice cultivars.

Authors: Anum, Jazba, O'Shea, Charlotte, Zeeshan Hyder, M., Farrukh, Sumaira, Skriver, Karen, Malik, Saad Imran, Yasmin, Tayyaba

Source: Molecular Biology Reports; Jan2022, Vol. 49 Issue 1, p293-302, 10p

Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold.

Authors: Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O’Shea, Charlotte, Lindorff-Larsen, Kresten, Winther, Jakob Rahr

Source: Journal of Physical Chemistry B; 10/14/2021, Vol. 125 Issue 40, p11141-11149, 9p

Subgroup-specific intrinsic disorder profiles of arabidopsis NAC transcription factors: Identification of functional hotspots

Authors: Stender, Emil G, O'Shea, Charlotte, Skriver, Karen

Source: Plant signaling & behavior. 10(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050607419.0x000001&indx=1&recIds=ETOCvdc_100050607419.0x000001

Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding.

Authors: Theisen, Frederik Friis, Staby, Lasse, Tidemand, Frederik Grønbæk, O’Shea, Charlotte, Prestel, Andreas, Willemoës, Martin, Kragelund, Birthe B., Skriver, Karen

Source: Journal of the American Chemical Society; 9/15/2021, Vol. 143 Issue 36, p14540-14550, 11p

Structure, Function and Networks of Transcription Factors Involved in Abiotic Stress Responses.

Authors: Lindemose, Søren¹ slindemose@bio.ku.dk, O'Shea, Charlotte¹ coshea@bio.ku.dk, Jensen, Michael Krogh² mikjensen@bio.ku.dk, Skriver, Karen¹ kskriver@bio.ku.dk

Source: International Journal of Molecular Sciences. Mar2013, Vol. 14 Issue 3, p5842-5878. 37p. 3 Diagrams.

Subject Terms: *TRANSCRIPTION factors, *EFFECT of stress on plants, *OSMOLAR concentration, *PLANT hormones, *PROTEIN structure, *GENE regulatory networks, *GENETIC regulation

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Effects of Flanking Disorder on the Behaviour of Ordered Domains

Authors: Kemplen, Katie R., Heidarsson, Petur O., Staby, Lasse, O'Shea, Charlotte, Skriver, Karen, Kragelund, Birthe B.

Source: Biophysical journal. 112(3):58a-58a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100054026962.0x000001&indx=1&recIds=ETOCvdc_100054026962.0x000001

Improving folding properties of computationally designed proteins.

Authors: Bjerre, Benjamin¹, Nissen, Jakob¹, Madsen, Mikkel¹, Fahrig-Kamarauskaitė, Jūratė¹, Norrild, Rasmus K.¹, Holm, Peter C.¹, Nordentoft, Mathilde K.¹, O'Shea, Charlotte¹, Willemoës, Martin¹, Johansson, Kristoffer E.¹, Winther, Jakob R.¹, jrwinther@bio.ku.dk

Source: PEDS: Protein Engineering, Design & Selection; Mar2019, Vol. 32 Issue 3, p145-151, 7p