Euglobulin clot lysis time reveals a high frequency of fibrinolytic activation in trauma

Authors: Ilich, Anton, Kumar, Vaibhav, Ferrara, Michael J., Henderson, Michael W., Noubouossie, Denis F., Jenkins, Donald H., Kozar, Rosemary A., Park, Myung S., Key, Nigel S.

Source: In Thrombosis Research August 2021 204:22-28

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Authors: Henderson, Michael W., Sparkenbaugh, Erica M., Wang, Shaobin, Ilich, Anton, Noubouossie, Denis F., Mailer, Reiner, Renné, Thomas, Flick, Matthew J., Luyendyk, James P., Chen, Zu-Lin, Strickland, Sidney, Stravitz, R. Todd, McCrae, Keith R., Key, Nigel S. ^**, Pawlinski, Rafal ^*

Source: In Blood 22 July 2021 138(3):259-272

Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma

Authors: Thålin, Charlotte ^*, Aguilera, Katherina, Hall, Nathan W., Marunde, Matthew R., Burg, Jonathan M., Rosell, Axel, Daleskog, Maud, Månsson, Maja, Hisada, Yohei, Meiners, Matthew J., Sun, Zu‐Wen, Whelihan, Matthew F., Cheek, Marcus A., Howard, Sarah A., Saxena‐Beem, Shruti, Noubouossie, Denis F., Key, Nigel S., Sheikh, Saira Z., Keogh, Michael‐Christopher, Cowles, Martis W., Lundström, Staffan, Mackman, Nigel, Wallén, Håkan, Johnstone, Andrea L.

Source: In Journal of Thrombosis and Haemostasis October 2020 18(10):2732-2743

Protease: Serpin complexes to assess contact system and intrinsic pathway activation

Authors: Henderson, Michael W., Noubouossie, Denis F., Ilich, Anton, Wilson, Kathy J., Pawlinski, Rafal, Monroe, Dougald M., Key, Nigel S. ^*

Source: In Research and Practice in Thrombosis and Haemostasis July 2020 4(5):789-798

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Authors: Noubouossie, Denis F. ^{1, 2}, Henderson, Michael W. ^{2, 3}, Mooberry, Micah ^{1, 2}, Ilich, Anton ^{1, 2}, Ellsworth, Patrick ^{1, 3}, Piegore, Mark ^{1, 2}, Skinner, Sarah C. ^{1, 2, 3}, Pawlinski, Rafal ^{1, 2}, Welsby, Ian ⁴, Renné, Thomas ⁵, Hoffman, Maureane ⁶, Monroe, Dougald M. ^{1, 2}, Key, Nigel S. ^{1, 1, 2, 3}

Source: In Blood 5 March 2020 135(10):755-765

Development and application of global assays of hyper‐ and hypofibrinolysis

Authors: Ilich, Anton, Noubouossie, Denis F., Henderson, Michael, Ellsworth, Patrick, Molitor, Kathleen F., Campello, Elena, Meeks, Shannon, Dunn, Amy, Park, Myung S., Pawlinski, Rafal, Simioni, Paolo, Shapiro, Amy, Key, Nigel S. ^*

Source: In Research and Practice in Thrombosis and Haemostasis January 2020 4(1):46-53

Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Authors: Faes, Camille, Ilich, Anton, Sotiaux, Amandine, Sparkenbaugh, Erica M., Henderson, Michael W., Buczek, Laura, Beckman, Joan D., Ellsworth, Patrick, Noubouossie, Denis F., Bhoopat, Lantarima, Piegore, Mark, Renoux, Céline, Bergmeier, Wolfgang, Park, Yara, Ataga, Kenneth I., Cooley, Brian, Wolberg, Alisa S., Key, Nigel S., Pawlinski, Rafal ^*

Source: In Blood 6 June 2019 133(23):2529-2541

Neutrophils: back in the thrombosis spotlight

Authors: Noubouossie, Denis F., Reeves, Brandi N., Strahl, Brian D., Key, Nigel S. ^*

Source: In Blood 16 May 2019 133(20):2186-2197

Passenger Lymphocyte Syndrome and Autoimmune Hypothyroidism Following Hematopoietic Stem Cell Transplantation.

Authors: Noubouossie, Denis F.¹ (AUTHOR), Zaanona, Mohammed I. A.² (AUTHOR), Costa, Luciano J.² (AUTHOR), Pham, Huy P.³ (AUTHOR), Marques, Marisa B.¹ (AUTHOR), Di Stasi, Antonio² (AUTHOR)

Source: Case Reports in Immunology. 6/23/2022, p1-6. 6p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *THYROIDITIS, *AUTOIMMUNE thyroiditis, *RED blood cell transfusion, *STEM cell transplantation, *BLOOD group incompatibility, *BLOOD groups

In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps

Authors: Noubouossie, Denis F., Whelihan, Matthew F., Yu, Yuan-Bin, Sparkenbaugh, Erica, Pawlinski, Rafal, Monroe, Dougald M., Key, Nigel S.

Source: In Blood 23 February 2017 129(8):1021-1029

Red cell extracellular vesicles and coagulation activation pathways.

Authors: Noubouossie, Denis F., Key, Nigel S.

Source: Current Opinion in Hematology; Nov2023, Vol. 30 Issue 6, p194-202, 9p

Elevated Plasma Fibrinogen Is Associated With Excessive Inflammation and Disease Severity in COVID-19 Patients.

Authors: Sui, Jingrui, Noubouossie, Denis F., Gandotra, Sheetal, Cao, Liyun

Source: Frontiers in Cellular & Infection Microbiology; 8/3/2021, Vol. 11, p1-7, 7p

Subject Terms: COVID-19, FIBRINOGEN, CARDIOVASCULAR diseases, COPEPTINS, SENSITIVITY & specificity (Statistics), HEART injuries

Geographic Terms: BIRMINGHAM (England)

Company/Entity: UNIVERSITY of Alabama (Tuscaloosa, Ala.)

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Thrombin Generation Test During Asparaginase Treatment In Children With Acute Lymphoblastic Leukemia

Authors: Rozen, Laurence ^*, Noubouossie, Denis F ^*, Dedeken, Laurence, Huybrechts, Sophie ^*, Le, Phu-Quoc, Ferster, Alina, Demulder, Anne ^*

Source: In Blood 15 November 2013 122(21):2367-2367

Characteristics of Sickle Cell Disease Children Having Elevated Thrombin Potential

Authors: Noubouossie, Denis F ^*, Le, Phu-Quoc, Rozen, Laurence ^*, Willems, Dominique ^*, Bhavna, Mahadeb ^*, Mujinga, Malou Ngalula ^*, Demulder, Anne ^*, Ferster, Alina

Source: In Blood 16 November 2012 120(21):4762-4762

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Towards An Improvement of the Coagulation Imbalance in Sickle Cell Disease After Hematopoietic Stem Cell Transplantation: A Preliminary Study

Authors: Noubouossie, Denis F ^*, Emmerechts, Jan ^*, Debaugnies, France ^*, Le, Phu-Quoc, Rozen, Laurence ^*, Hoylaerts, Marc F., Demulder, Anne ^*, Ferster, Alina

Source: In Blood 18 November 2011 118(21):4840-4840

Is There Any Improvement of the Coagulation Imbalance in Sickle Cell Disease after Hematopoietic Stem Cell Transplantation?

Authors: Rozen, Laurence¹ (AUTHOR) laurence.rozen@lhub-ulb.be, Noubouossie, Denis F.¹ (AUTHOR) Anne.DEMULDER@LHUB-ULB.BE, Dedeken, Laurence² (AUTHOR) laurence.dedeken@huderf.be, Lê, Phu Quoc² (AUTHOR) phuquoc.le@huderf.be, Ferster, Alina² (AUTHOR) alina.ferster@huderf.be, Demulder, Anne¹ (AUTHOR)

Source: Journal of Clinical Medicine. Nov2019, Vol. 8 Issue 11, p1796-1796. 1p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *SICKLE cell anemia, *BLOOD coagulation