Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2

Authors: Shuyong Zhu, Nancy Stanslowsky, Jorge Fernández-Trillo, Tamrat M. Mamo, Pengfei Yu, Norman Kalmbach, Birgit Ritter, Reto Eggenschwiler, Werner J.D. Ouwendijk, David Mzinza, Likai Tan, Andreas Leffler, Michael Spohn, Richard J.P. Brown, Kai A. Kropp, Volkhard Kaever, Teng-Cheong Ha, Pratibha Narayanan, Adam Grundhoff, Reinhold Förster, Axel Schambach, Georges M.G.M. Verjans, Manuela Schmidt, Andreas Kispert, Tobias Cantz, Ana Gomis, Florian Wegner, Abel Viejo-Borbolla

Source: Stem Cell Research, Vol 56, Iss , Pp 102535- (2021)

Subject Terms: Human induced pluripotent stem cells, Small molecule-derived neural precursor cells, Low threshold mechanoreceptors, Bulbous sensory nerve ending, Piezo1, Piezo2, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506121003822; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/c19fa53982d04aa9802dafcb4602256b

Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins

Authors: Masin Abo-Rady, Norman Kalmbach, Arun Pal, Carina Schludi, Antje Janosch, Tanja Richter, Petra Freitag, Marc Bickle, Anne-Karin Kahlert, Susanne Petri, Stefan Stefanov, Hannes Glass, Selma Staege, Walter Just, Rajat Bhatnagar, Dieter Edbauer, Andreas Hermann, Florian Wegner, Jared L. Sterneckert

Source: Stem Cell Reports, Vol 14, Iss 3, Pp 390-405 (2020)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221367112030031X; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/15576128a76a4db4a3714084cbbcfe19

Reduced Expression of GABAA Receptor Alpha2 Subunit Is Associated With Disinhibition of DYT-THAP1 Dystonia Patient-Derived Striatal Medium Spiny Neurons

Authors: Selma Staege, Anna Kutschenko, Hauke Baumann, Hannes Glaß, Lisa Henkel, Thomas Gschwendtberger, Norman Kalmbach, Martin Klietz, Andreas Hermann, Katja Lohmann, Philip Seibler, Florian Wegner

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: DYT-THAP1, genetic dystonia, induced pluripotent stem cells, striatal medium spiny neurons, GABAA receptor, calcium dynamics, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.650586/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/e430a2e0bfeb42c5b6f33e85eb50634e

Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS

Authors: René Günther, Arun Pal, Chloe Williams, Vitaly L. Zimyanin, Maria Liehr, Cläre von Neubeck, Mechthild Krause, Mrudula G. Parab, Susanne Petri, Norman Kalmbach, Stefan L. Marklund, Jared Sterneckert, Peter Munch Andersen, Florian Wegner, Jonathan D. Gilthorpe, Andreas Hermann

Source: Cells, Vol 11, Iss 7, p 1246 (2022)

Subject Terms: SOD1, ALS1, mitochondria, live cell imaging, axonal trafficking, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/7/1246; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a384eecc4dc6440ea19379b4d2551e7d

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