Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies

Authors: Bianchi, Matteo, Kozyrev, Sergey V., Sandling, Johanna K., Rönnblom, Lars, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Leonard, Dag, Dahlqvist, Johanna, Lidén, Maria, Mathioudaki, Argyri, Meadows, Jennifer RS., Nordin, Jessika, Nordmark, Gunnel, Lundberg, Ingrid E., Notarnicola, Antonella, Padyukov, Leonid, Tjärnlund, Anna, Dastmalchi, Maryam, Eriksson, Daniel, Molberg, Øyvind, Andersson, Helena, Lindblad-Toh, Kerstin, Farias, Fabiana H.G., Wahren-Herlenius, Marie, Jalal, Awat, Hanna, Balsam, Hellström, Helena, Husmark, Tomas, Häggström, Åsa, Svärd, Anna, Skogh, Thomas, Diederichsen, Louise Pyndt, Lamb, Janine A., Rothwell, Simon, Chinoy, Hector, Cooper, Robert G., Pielberg, Gerli Rosengren, Lobell, Anna, Karlsson, Åsa, Murén, Eva, Ahlgren, Kerstin M., Andersson, Göran, Landegren, Nils, Kämpe, Olle, Söderkvis, Peter, Leclair, Valérie, Galindo-Feria, Angeles S., Kryštůfková, Olga, Zargar, Sepehr Sarrafzadeh, Mann, Herman, Klein, Martin, Tansley, Sarah, McHugh, Neil, Vencovský, Jiri, Holmqvist, Marie, Diaz-Gallo, Lina-Marcela

Source: In eBioMedicine October 2023 96

Experiences in implementing immunopsychiatry in real life

Authors: Cunningham, Janet L., Nordmark, Gunnel, Fällmar, David, Cervenka, Simon, Gallwitz, Maike, Säll, Roland, Schmidt, Peter T., Rönnelid, Johan, Persson, Barbro, Kindmark, Andreas, Burman, Joachim

Source: In Journal of Affective Disorders Reports July 2023 13

Epigenetic alterations in primary Sjögren's syndrome – an overview

Authors: Imgenberg-Kreuz, Juliana, Sandling, Johanna K., Nordmark, Gunnel

Source: In Clinical Immunology November 2018 196:12-20

An exploratory study of the damage markers NfL, GFAP, and t-Tau, in cerebrospinal fluid and other findings from a patient cohort enriched for suspected autoimmune psychiatric disease.

Authors: Syk, Mikaela, Tornvind, Emma, Gallwitz, Maike, Fällmar, David, Amandusson, Åsa, Rothkegel, Holger, Danfors, Torsten, Thulin, Måns, Rasmusson, Annica J., Cervenka, Simon, Pollak, Thomas A., Endres, Dominique, van Elst, Ludger Tebartz, Bodén, Robert, Nilsson, Björn M., Nordmark, Gunnel, Burman, Joachim, Cunningham, Janet L.

Source: Translational Psychiatry; 7/24/2024, Vol. 14 Issue 1, p1-11, 11p

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome

Authors: Harris, Valerie M., Sharma, Rohan, Cavett, Joshua, Kurien, Biji T., Liu, Ke, Koelsch, Kristi A., Rasmussen, Astrid, Radfar, Lida, Lewis, David, Stone, Donald U., Kaufman, C. Erick, Li, Shibo, Segal, Barbara, Wallace, Daniel J., Weisman, Michael H., Venuturupalli, Swamy, Kelly, Jennifer A., Alarcon-Riquelme, Marta E., Pons-Estel, Bernardo, Jonsson, Roland, Lu, Xianglan, Gottenberg, Jacques-Eric, Anaya, Juan-Manuel, Cunninghame-Graham, Deborah S., Huang, Andrew J.W., Brennan, Michael T., Hughes, Pamela, Alevizos, Ilias, Miceli-Richard, Corinne, Keystone, Edward C., Bykerk, Vivian P., Hirschfield, Gideon, Xie, Gang, Ng, Wan-Fai, Nordmark, Gunnel, Bucher, Sara Magnusson, Eriksson, Per, Omdal, Roald, Rhodus, Nelson L., Rischmueller, Maureen, Rohrer, Michael, Wahren-Herlenius, Marie, Witte, Torsten, Mariette, Xavier, Lessard, Christopher J., Harley, John B., Sivils, Kathy L., Scofield, R. Hal

Source: In Clinical Immunology July 2016 168:25-29

Multimodal Single-Cell Sequencing of B Cells in Primary Sjögren’s Syndrome.

Authors: Arvidsson, Gustav, Czarnewski, Paulo, Johansson, Alina, Raine, Amanda, Imgenberg-Kreuz, Juliana, Nordlund, Jessica, Nordmark, Gunnel, Syvänen, Ann-Christine

Source: Arthritis & Rheumatology; Feb2024, Vol. 76 Issue 2, p255-267, 14p

Subject Terms: RNA analysis, AUTOANTIBODIES, B cells, SEQUENCE analysis, IMMUNOGLOBULINS, GENETIC mutation, CELL receptors, MOLECULAR pathology, COMPARATIVE studies, GENE expression profiling, DESCRIPTIVE statistics, SJOGREN'S syndrome, PHENOTYPES

Examining the biological pathways underlying clinical heterogeneity in Sjogren's syndrome: proteomic and network analysis.

Authors: Berry, Joe Scott, Tarn, Jessica, Casement, John, Duret, Pierre- Marie, Scott, Lauren, Wood, Karl, Johnsen, Svein- Joar, Nordmark, Gunnel, Pensec, Valérie Devauchelle, Seror, Raphaele, Fisher, Benjamin, Barone, Fransesca, Bowman, Simon J., Bombardieri, Michele, Lendrem, Dennis, Felten, Renaud, Gottenberg, Jacques- Eric, Wan- Fai Ng

Source: Annals of the Rheumatic Diseases; Jan2024, Vol. 83 Issue 1, p88-95, 8p

Three Functional Variants of IFN Regulatory Factor 5 (IRF5) Define Risk and Protective Haplotypes for Human Lupus

Authors: Graham, Robert R., Kyogoku, Chieko, Sigurdsson, Snaevar, Vlasova, Irina A., Davies, Leela R. L., Baechler, Emily C., Plenge, Robert M., Koeuth, Thearith, Ortmann, Ward A., Hom, Geoffrey, Bauer, Jason W., Gillett, Clarence, Burtt, Noel, Graham, Deborah S. Cunninghame, Onofrio, Robert, Petri, Michelle, Gunnarsson, Iva, Svenungsson, Elisabet, Rönnblom, Lars, Nordmark, Gunnel, Gregersen, Peter K., Moser, Kathy, Gaffney, Patrick M., Criswell, Lindsey A., Vyse, Timothy J., Syvänen, Ann-Christine, Bohjanen, Paul R., Daly, Mark J., Behrens, Timothy W., Altshuler, David

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Apr . 104(16), 6758-6763.

Access URL: https://www.jstor.org/stable/25427456

Use of a commercial line blot assay as a screening test for autoantibodies in inflammatory myopathies

Authors: Rönnelid, Johan, Barbasso Helmers, Sevim, Storfors, Helena, Grip, Katarina, Rönnblom, Lars, Franck-Larsson, Karin, Nordmark, Gunnel, Lundberg, Ingrid E.

Source: In Autoimmunity Reviews 2009 9(1):58-61

Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling.

Authors: Lundtoft, Christian¹, Pucholt, Pascal¹, Imgenberg-Kreuz, Juliana¹, Carlsson-Almlöf, Jonas², Eloranta, Maija-Leena¹, Syvänen, Ann-Christine², Nordmark, Gunnel¹, Sandling, Johanna K.¹, Kockum, Ingrid³, Olsson, Tomas³, Rönnblom, Lars¹, Hagberg, Niklas¹, niklas.hagberg@medsci.uu.se

Source: PLoS Genetics; 10/26/2020, Vol. 16 Issue 10, p1-22, 22p

Characterization and outcomes of 414 patients with primary SS who developed haematological malignancies.

Authors: Hernández-Molina, Gabriela, Kostov, Belchin, Brito-Zerón, Pilar, Vissink, Arjan, Mandl, Thomas, Hinrichs, Anneline C, Quartuccio, Luca, Baldini, Chiara, Seror, Raphaele, Szántó, Antonia, Isenberg, David, Gerli, Roberto, Nordmark, Gunnel, Rasmussen, Astrid, Solans-Laque, Roser, Hofauer, Benedikt, Sène, Damien, Pasoto, Sandra G, Rischmueller, Maureen, Praprotnik, Sonja

Source: Rheumatology; Jan2023, Vol. 62 Issue 1, p243-255, 13p

Subject Terms: LYMPHOID tissue, DISEASE relapse, HEMATOLOGIC malignancies, SJOGREN'S syndrome, LYMPHOMAS, LYMPHOPROLIFERATIVE disorders, SYMPTOMS

Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus.

Authors: Sigurdsson, Snaevar, Nordmark, Gunnel, Göring, Harald H. H.

Source: American Journal of Human Genetics; March 2005, Vol. 76 Issue 3, p528-537, 10p

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and Clinical Manifestations.

Authors: Diaz‐Gallo, Lina‐Marcela, Oke, Vilija, Lundström, Emeli, Elvin, Kerstin, Ling Wu, Yee, Eketjäll, Susanna, Zickert, Agneta, Gustafsson, Johanna T., Jönsen, Andreas, Leonard, Dag, Birmingham, Daniel J., Nordmark, Gunnel, Bengtsson, Anders A., Rönnblom, Lars, Gunnarsson, Iva, Yu, Chack‐Yung, Padyukov, Leonid, Svenungsson, Elisabet

Source: ACR Open Rheumatology; Jan2022, Vol. 4 Issue 1, p27-39, 13p

Subject Terms: SYSTEMIC lupus erythematosus, AUTOANTIBODIES, SJOGREN'S syndrome, SYMPTOMS, GENOTYPES

DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome.

Authors: Imgenberg-Kreuz, Juliana, Sandling, Johanna K., Norheim, Katrine Brække, Johnsen, Svein Joar Auglænd, Omdal, Roald, Syvänen, Ann-Christine, Svenungsson, Elisabet, Rönnblom, Lars, Eloranta, Maija-Leena, Nordmark, Gunnel

Source: Frontiers in Immunology; 7/16/2021, Vol. 12, p1-13, 13p

Subject Terms: TYPE I interferons, CLINICAL trials monitoring, INTERFERONS, DNA, DNA methylation

Geographic Terms: STAVANGER (Norway)

Association of Genes in the NF-κB Pathway with Antibody-Positive Primary Sjögren's Syndrome.

Authors: Nordmark, Gunnel¹, Wang, Chuan², Vasaitis, Lilian¹, Eriksson, Per³, Theander, Elke⁴, Kvarnström, Marika⁵, Forsblad‐d'Elia, Helena⁶, Jazebi, Helmi^5,7, Sjöwall, Christopher³, Reksten, Tove Ragna⁸, Brun, Johan G.^9,10, Jonsson, Malin V.^8,10,11, Johnsen, Svein J.¹², Wahren‐Herlenius, Marie⁵, Omdal, Roald¹², Jonsson, Roland^8,9, Bowman, Simon¹³, Ng, Wan‐Fai¹⁴, Eloranta, Maija‐Leena¹, Syvänen, Ann‐Christine²

Source: Scandinavian Journal of Immunology. Nov2013, Vol. 78 Issue 5, p447-454. 8p.

Subject Terms: *NF-kappa B, *IMMUNOGLOBULINS, *SJOGREN'S syndrome, *SINGLE nucleotide polymorphisms, *HAPLOTYPES, *AUTOANTIBODIES, *META-analysis

Genetics and epigenetics in primary Sjögren's syndrome.

Authors: Imgenberg-Kreuz, Juliana, Rasmussen, Astrid, Sivils, Kathy, Nordmark, Gunnel

Source: Rheumatology; May2021, Vol. 60 Issue 5, p2085-2098, 14p

Subject Terms: GENETICS, DNA methylation, SJOGREN'S syndrome, EPIGENOMICS

Cigarette smoking patterns preceding primary Sjögren's syndrome.

Authors: Mofors, Johannes, Björk, Albin, Andersson, Elina Richardsdotter, Kvarnström, Marika, d'Elia, Helena Forsblad, Magnusson-Bucher, Sara, Padyukov, Leonid, Kockum, Ingrid, Hillert, Jan, Eriksson, Per, Mandl, Thomas, Nordmark, Gunnel, Alfredsson, Lars, Wahren-Herlenius, Marie

Source: RMD Open; 9/29/2020, Vol. 6, p1-9, 9p

Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus.

Authors: Nordmark, Gunnel¹ (AUTHOR) gunnel.nordmark@medsci.uu.se, Bengtsson, Christine² (AUTHOR), Larsson, Anders³ (AUTHOR), Karlsson, F. Anders⁴ (AUTHOR), Sturfelt, Gunnar² (AUTHOR), Rönnblom, Lars¹ (AUTHOR)

Source: Autoimmunity. Nov2005, Vol. 38 Issue 7, p531-540. 10p. 2 Charts, 3 Graphs.

Subject Terms: *SYSTEMIC lupus erythematosus, *QUALITY of life, *SKIN diseases, *DEHYDROEPIANDROSTERONE, *GLUCOCORTICOIDS, *ADRENOCORTICAL hormones, *AUTOIMMUNE diseases

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