Immunomodulatory imide drugs inhibit human detrusor smooth muscle contraction and growth of human detrusor smooth muscle cells, and exhibit vaso-regulatory functions

Authors: Tamalunas, Alexander, Wendt, Amin, Springer, Florian, Vigodski, Victor, Trieb, Moritz, Eitelberger, Nikolaus, Poth, Henrik, Ciotkowska, Anna, Rutz, Beata, Hu, Sheng, Schulz, Heiko, Ledderose, Stephan, Rogenhofer, Nina, Kolben, Thomas, Nössner, Elfriede, Stief, Christian G., Hennenberg, Martin

Source: In Biomedicine & Pharmacotherapy August 2024 177

Early recovery of leukocyte subsets is associated with favorable progression-free survival in patients with inoperable stage II/III NSCLC after multimodal treatment: a prospective explorative study.

Authors: Hofer, Thomas P., Nieto, Alexander E., Käsmann, Lukas, Pelikan, Carolyn J., Taugner, Julian, Mathur, Saloni, Eze, Chukwuka, Belka, Claus, Manapov, Farkhad, Noessner, Elfriede

Source: Radiation Oncology; 3/20/2025, Vol. 20 Issue 1, p1-12, 12p

Immune infiltrates in patients with localised high-risk soft tissue sarcoma treated with neoadjuvant chemotherapy without or with regional hyperthermia: A translational research program of the EORTC 62961-ESHO 95 randomised clinical trial

Authors: Issels, Rolf D., Noessner, Elfriede, Lindner, Lars H., Schmidt, Michael, Albertsmeier, Markus, Blay, Jean-Yves, Stutz, Emanuel, Xu, Yujun, Buecklein, Veit, Altendorf-Hofmann, Annelore, Abdel-Rahman, Sultan, Mansmann, Ulrich, von Bergwelt-Baildon, Michael, Knoesel, Thomas

Source: In European Journal of Cancer November 2021 158:123-132

T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice

Authors: Quitt, Oliver, Luo, Shanshan, Meyer, Marten, Xie, Zhe, Golsaz-Shirazi, Forough, Loffredo-Verde, Eva, Festag, Julia, Bockmann, Jan Hendrik, Zhao, Lili, Stadler, Daniela, Chou, Wen-Min, Tedjokusumo, Raindy, Wettengel, Jochen Martin, Ko, Chunkyu, Noeßner, Elfriede, Bulbuc, Nadja, Shokri, Fazel, Lüttgau, Sandra, Heikenwälder, Mathias, Bohne, Felix, Moldenhauer, Gerhard, Momburg, Frank, Protzer, Ulrike

Source: In Journal of Hepatology November 2021 75(5):1058-1071

Reduced frequency of perforin-positive CD8+ T cells in menstrual effluent of endometriosis patients

Authors: Schmitz, Timo ^*, Hoffmann, Verena, Olliges, Elisabeth, Bobinger, Alina, Popovici, Roxana, Nößner, Elfriede, Meissner, Karin ^**

Source: In Journal of Reproductive Immunology November 2021 148

INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer.

Authors: Maxwell, Melissa, Yan, Dingxue, Rivest, Brianna, Boone, Andrew, Cardia, James, Noessner, Elfriede

Source: Cancer Immunology, Immunotherapy; Dec2024, Vol. 73 Issue 12, p1-12, 12p

Subject Terms: KILLER cells, T-cell exhaustion, CELL-mediated cytotoxicity, MANUFACTURING cells, ANTIGEN presentation

Epigenetics in non-classical monocytes support their pro-inflammatory gene expression

Authors: Zhang, Lu, Hofer, Thomas P., Zawada, Adam M., Rotter, Björn, Krezdorn, Nicolas, Noessner, Elfriede, Devaux, Yvan, Heine, Gunnar, Ziegler-Heitbrock, Loems ^*

Source: In Immunobiology May 2020 225(3)

Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma – a case report

Authors: Issels, Rolf D., Lindner, Lars H., von Bergwelt-Baildon, Michael, Lang, Peter, Rischpler, Christoph, Diem, Heinz, Mosetter, Barbara, Eckl, Judith, Schendel, Dolores J., Salat, Christoph, Stötzer, Oliver, Burdach, Stefan, von Luettichau-Teichert, Irene, Handgretinger, Rupert, Neumann, Jens, Kirchner, Thomas, Steiger, Katja, Boxberg, Melanie, Mansmann, Ulrich, Multhoff, Gabriele, Noessner, Elfriede

Source: International journal of hyperthermia. 37(1):55-65

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123913190.0x000001&indx=1&recIds=ETOCvdc_100123913190.0x000001

A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas

Authors: Orth, Martin F., Buecklein, Veit Leonhard, Kampmann, Eric, Subklewe, Marion, Noessner, Elfriede, Cidre-Aranaz, Florencia, Romero-Pérez, Laura, Wehweck, Fabienne Sophie, Lindner, Lars, Issels, Rolf, Kirchner, Thomas, Altendorf-Hofmann, Annelore, Grünewald, Thomas G. P., Knösel, Thomas

Source: Cancer immunology, immunotherapy. 69(7):1353-1362

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167889425.0x000001&indx=1&recIds=ETOCvdc_100167889425.0x000001

Collagen density regulates the activity of tumor-infiltrating T cells

Authors: Kuczek, Dorota, Larsen, Anne, Thorseth, Marie-Louise, Carretta, Marco, Kalvisa, Adrija, Siersbæk, Majken, Simões, Ana, Roslind, Anne, Engelholm, Lars, Noessner, Elfriede, Donia, Marco, Svane, Inge, Straten, Per, Grøntved, Lars, Madsen, Daniel

Source: Journal for immunotherapy of cancer. 7(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190702684.0x000001&indx=1&recIds=ETOCvdc_100190702684.0x000001

Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells

Authors: Essig, Katharina, Hu, Desheng, Guimaraes, Joao C., Alterauge, Dominik, Edelmann, Stephanie, Raj, Timsse, Kranich, Jan, Behrens, Gesine, Heiseke, Alexander, Floess, Stefan, Klein, Juliane, Maiser, Andreas, Marschall, Susan, Hrabĕ de Angelis, Martin, Leonhardt, Heinrich, Calkhoven, Cornelis F., Noessner, Elfriede, Brocker, Thomas, Huehn, Jochen, Krug, Anne B., Zavolan, Mihaela, Baumjohann, Dirk, Heissmeyer, Vigo

Source: In Immunity 19 December 2017 47(6):1067-1082

Treatment of Dermal Fibroblasts with GPI-Anchored Human TIMP-1 Protein Moderates Processes Linked to Scar Formation

Authors: Djafarzadeh, Roghieh, Notohamiprodjo, Susan, Rieth, Nicole, Hofstetter, Monika, Noessner, Elfriede, Nelson, Peter J. ^*

Source: In Journal of Investigative Dermatology March 2013 133(3):803-811

Proapoptotic and Antiapoptotic Proteins of the Bcl-2 Family Regulate Sensitivity of Pancreatic Cancer Cells Toward Gemcitabine and T-Cell–mediated Cytotoxicity

Authors: Bauer, Christian, Hees, Claudia, Sterzik, Alexander, Bauernfeind, Franz, Mak’Anyengo, Rachel, Duewell, Peter, Lehr, Hans-Anton, Noessner, Elfriede, Wank, Rudolf, Trauzold, Anna, Endres, Stefan, Dauer, Marc, Schnurr, Max

Source: Journal of immunotherapy. 38(3):116-126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050739748.0x000001&indx=1&recIds=ETOCvdc_100050739748.0x000001

A Lysine Residue at the C-Terminus of MHC Class I Ligands Correlates with Low C-Terminal Proteasomal Cleavage Probability.

Authors: Schmalen, Adrian, Kammerl, Ilona E., Meiners, Silke, Noessner, Elfriede, Deeg, Cornelia A., Hauck, Stefanie M.

Source: Biomolecules (2218-273X); Sep2023, Vol. 13 Issue 9, p1300, 18p

Subject Terms: C-terminal residues, T cell receptors, PEPTIDES, LIGANDS (Biochemistry), LYSINE, PROBABILITY theory

Hsp70, a messenger from hyperthermia for the immune system

Authors: Jolesch, Anna, Elmer, Katharina, Bendz, Henriette, Issels, Rolf D., Noessner, Elfriede

Source: In European Journal of Cell Biology 2012 91(1):48-52

Human Renal Cell Carcinoma Induces a Dendritic Cell Subset That Uses T-Cell Crosstalk for Tumor-Permissive Milieu Alterations

Authors: Figel, Ainhoa-M., Brech, Dorothee, Prinz, Petra U., Lettenmeyer, Ulrike K., Eckl, Judith, Turqueti-Neves, Adriana, Mysliwietz, Josef, Anz, David, Rieth, Nicole, Muenchmeier, Niklas, Buchner, Alexander, Porubsky, Stefan, Siegert, Sabine I., Segerer, Stephan, Nelson, Peter J., Noessner, Elfriede

Source: In The American Journal of Pathology 2011 179(1):436-451

TOP-355-YI T cells expressing HBV-specific chimeric antigen receptors harboring a Fab fragment control HBV infection in mice

Authors: Xie, Zhe, Quitt, Oliver, Kosinska, Anna D., Wolff, Lisa, Nößner, Elfriede, Protzer, Ulrike

Source: In Journal of Hepatology June 2024 80 Supplement 1:S727-S727

Modified vaccinia virus Ankara delivers a robust surrogate marker for immune monitoring to sarcoma cells even if cells are being exposed to chemotherapy and heat treatment

Authors: Tschoep-Lechner, Katharina, Drexler, Ingo, Hammer, Doreen, Neumann, Daniel, Pohla, Heike, Sutter, Gerd, Noessner, Elfriede, Issels, Rolf-Dieter

Source: International journal of hyperthermia. 28(1):33-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106142939.0x000001&indx=1&recIds=ETOCvdc_100106142939.0x000001

Prostate cancer lesions are surrounded by FOXP3 +, PD-1 + and B7-H1 + lymphocyte clusters

Authors: Ebelt, Kathleen, Babaryka, Gregor, Frankenberger, Bernhard, Stief, Christian G., Eisenmenger, Wolfgang, Kirchner, Thomas, Schendel, Dolores J., Noessner, Elfriede

Source: In European Journal of Cancer 2009 45(9):1664-1672

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

Authors: Bendz, Henriette, Marincek, Boris-Christian, Momburg, Frank, Ellwart, Joachim W., Issels, Rolf D., Nelson, Peter J., Noessner, Elfriede

Source: In Journal of Biological Chemistry 26 September 2008 283(39):26477-26483