Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor

Authors: Nobuyuki Takahashi, Lorinc Pongor, Shivam P. Agrawal, Mariya Shtumpf, Ankita Gurjar, Vinodh N. Rajapakse, Ahmad Shafiei, Christopher W. Schultz, Sehyun Kim, Diana Roame, Paula Carter, Rasa Vilimas, Samantha Nichols, Parth Desai, William Douglas Figg Sr., Mohammad Bagheri, Vladimir B. Teif, Anish Thomas

Source: Genome Medicine, Vol 17, Iss 1, Pp 1-16 (2025)

Subject Terms: Circulating cell-free DNA, Circulating tumor DNA, Whole genome sequencing, Transcription factor binding site, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/8d439999f8b74064b14b30011a82414b

Cooperation beyond group boundaries is evaluated differently depending on the existence of intergroup competition

Authors: Wakaba Tateishi, Nobuyuki Takahashi

Source: Frontiers in Behavioral Economics, Vol 4 (2025)

Subject Terms: reputation, cooperation, intergroup, indirect reciprocity, behavioral experiment, Economic theory. Demography, HB1-3840

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frbhe.2025.1493427/full; https://doaj.org/toc/2813-5296

Access URL: https://doaj.org/article/831e641a96fc4deeb5bef53b6fcd01b9

Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

Authors: Nobuyuki Takahashi, Yukiko Mori, Kenji Momo, Hidetomo Murakami, Hironori Tanaka

Source: Clinical Case Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)

Subject Terms: duloxetine, neuropathic pain, small‐cell lung cancer, syndrome of inappropriate antidiuretic hormone secretion, uric acid, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0904

Access URL: https://doaj.org/article/9d714d0bd4b646dbba521c357a0d978a

Impacts of low birthweight on kidney development and intergenerational growth of the offspring

Authors: Akiyo Sekimoto, Yoko Takaso, Haruka Saruyama, Masataka Ookawa, Mari Yamamoto, Takafumi Toyohara, Daisuke Saigusa, Tomoko Fukuuchi, Mayu Otsuka, Yui Fushiki, Seiko Yamakoshi, Kayo Tanaka, Tomoaki Ikeda, Tetsuhiro Tanaka, Nobuyuki Takahashi, Eikan Mishima, Emiko Sato

Source: iScience, Vol 27, Iss 11, Pp 111159- (2024)

Subject Terms: Biological sciences, Physiology, Metabolomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224023848; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/21c9403e80984696abce08f775427620

The Many Faces of Protease-Activated Receptor 2 in Kidney Injury

Authors: Yuji Oe, Tetsuhiro Tanaka, Nobuyuki Takahashi

Source: Biomedicines, Vol 13, Iss 2, p 414 (2025)

Subject Terms: coagulation proteases, chronic kidney disease, acute kidney injury, inflammation, fibrosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/13/2/414; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/a0fe5b0e3988421a9a0f26940ab93c07

CGRP-monoclonal antibodies in Japan: insights from an online survey of physician members of the Japanese headache society

Authors: Tsubasa Takizawa, Keiko Ihara, Narumi Watanabe, Ryo Takemura, Nobuyuki Takahashi, Naoki Miyazaki, Mamoru Shibata, Keisuke Suzuki, Noboru Imai, Norihiro Suzuki, Koichi Hirata, Takao Takeshima, Jin Nakahara

Source: The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-10 (2024)

Subject Terms: CGRP monoclonal antibody, Migraine, Japanese Headache Society, Guideline, Online survey, Cost, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1129-2377

Access URL: https://doaj.org/article/01b79095541b444eb414caea23415c35

Real-world evidence of fremanezumab for treating migraine in Japan: a retrospective study

Authors: Seiya Ohtani, Narumi Watanabe, Keiko Ihara, Nobuyuki Takahashi, Naoki Miyazaki, Kei Ishizuchi, Ryo Takemura, Satoko Hori, Jin Nakahara, Tsubasa Takizawa

Source: BMC Neurology, Vol 23, Iss 1, Pp 1-11 (2023)

Subject Terms: Fremanezumab, Migraine, Real-world evidence, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/541ece2af2964170882642e207eaf7ca

Significance of perilesional T1 hyperintense areas in the differential diagnosis of primary adult-type diffuse glioma: A case report

Authors: Akinari Yamano, MD, Kiyoyuki Yanaka, MD, PhD, Kuniyuki Onuma, MD, Kazuhiro Nakamura, MD, PhD, Nobuyuki Takahashi, MD, PhD, Hidehiro Kohzuki, MD, PhD, Noriaki Sakamoto, MD, PhD, Masahide Matsuda, MD, PhD, Eiichi Ishikawa, MD, PhD

Source: Radiology Case Reports, Vol 18, Iss 10, Pp 3448-3452 (2023)

Subject Terms: Glioma, Oligodendroglioma, Cavernous malformation, MRI, Perilesional T1 hyperintense area, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1930043323004636; https://doaj.org/toc/1930-0433

Access URL: https://doaj.org/article/8b8ea073a5c842a091c91d2a93e5ff8d

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer

Authors: Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien‐Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas

Source: EMBO Molecular Medicine, Vol 15, Iss 8, Pp 1-17 (2023)

Subject Terms: ATR inhibitor, biomarker, neuroendocrine, SCLC, synergy, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/6165ccece4b14143846203745ec9358e

The impact of the COVID‐19 pandemic on perioperative chemotherapy for breast cancer

Authors: Kaede Baba, Megumi Kawamoto, Kanako Mamishin, Mao Uematsu, Hikari Kiyohara, Akira Hirota, Nobuyuki Takahashi, Misao Fukuda, Shota Kusuhara, Hiromichi Nakajima, Chikako Funasaka, Takehiro Nakao, Chihiro Kondoh, Kenichi Harano, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Toshikatsu Kawasaki, Toru Mukohara

Source: Cancer Medicine, Vol 12, Iss 11, Pp 12095-12105 (2023)

Subject Terms: adjuvant chemotherapy, breast cancer, COVID‐19, neoadjuvant chemotherapy, SARS‐CoV‐2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/c0255b117bae403e9d5e854df13ba152

Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study

Authors: Keiko Ihara, Seiya Ohtani, Narumi Watanabe, Nobuyuki Takahashi, Naoki Miyazaki, Kei Ishizuchi, Satoko Hori, Ryo Takemura, Jin Nakahara, Tsubasa Takizawa

Source: The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-10 (2023)

Subject Terms: Migraine, Japan, CGRPmAbs, Headache, Erenumab, Galcanezumab, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1129-2377

Access URL: https://doaj.org/article/a0ddc0ff0f024cf09ca0ca1d5a466028

Diagnostic accuracy and clinical usefulness of erythrocyte creatine content to predict the improvement of anaemia in patients receiving maintenance haemodialysis

Authors: Ohki Hayashi, Seishi Nakamura, Tetsuro Sugiura, Shun Hasegawa, Yoshiaki Tsuka, Nobuyuki Takahashi, Sanae Kikuchi, Koichiro Matsumura, Toshika Okumiya, Masato Baden, Ichiro Shiojima

Source: BMC Nephrology, Vol 24, Iss 1, Pp 1-9 (2023)

Subject Terms: Erythrocyte creatine content, Erythropoiesis stimulating agent, Erythropoietin resistance, Haemodialysis, Renal anaemia, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2369

Access URL: https://doaj.org/article/6feceb4db1534476b48b69f9c048d595

Valerenic Acid Promotes Adipocyte Differentiation, Adiponectin Production, and Glucose Uptake via Its PPARγ Ligand Activity

Authors: Jun Takahashi, Nobuyuki Takahashi, Miki Tadaishi, Makoto Shimizu, Kazuo Kobayashi-Hattori

Source: ACS Omega, Vol 7, Iss 51, Pp 48113-48120 (2022)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/deac3a77a16f4e82bd51768b770f249a

Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer

Authors: Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien-Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Laurel L Bassel, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas

Source: EMBO Molecular Medicine, Vol 16, Iss 3, Pp 664-664 (2024)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/b57ab068599f4cb395448331d2cd662b

Allogeneic islet transplantation with monitoring of islet‐specific cellular autoimmunity in a Japanese patient with type 1 diabetes: A case report

Authors: Daisuke Chujo, Toshiaki Kurokawa, Akitsu Kawabe, Nobuyuki Takahashi, Fuyuki Inagaki, Koya Shinohara, Shotaro Hagiwara, Yoshihiro Edamoto, Norio Ohmagari, Fumihiko Hinoshita, Tsuyoshi Tajima, Hiroshi Kajio, Hiroshi Ohtsu, Nobuyuki Takemura, Shinichi Matsumoto, Masayuki Shimoda

Source: Journal of Diabetes Investigation, Vol 13, Iss 4, Pp 741-745 (2022)

Subject Terms: Autoimmune response, Type 1 diabetes mellitus, Islet transplantation, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/2040-1116; https://doaj.org/toc/2040-1124

Access URL: https://doaj.org/article/24301e867dee4c72a63e191cf0743177

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models

Authors: Delphine Lissa, Nobuyuki Takahashi, Parth Desai, Irena Manukyan, Christopher W. Schultz, Vinodh Rajapakse, Moises J. Velez, Deborah Mulford, Nitin Roper, Samantha Nichols, Rasa Vilimas, Linda Sciuto, Yuanbin Chen, Udayan Guha, Arun Rajan, Devon Atkinson, Rajaa El Meskini, Zoe Weaver Ohler, Anish Thomas

Source: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2b706f2be3074f5d81c7957af90cea3c

Erucin inhibits osteoclast formation via suppressing cell–cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts

Authors: Tomohiro Takagi, Hirofumi Inoue, Shungo Fujii, Nobuyuki Takahashi, Mariko Uehara

Source: BMC Research Notes, Vol 15, Iss 1, Pp 1-6 (2022)

Subject Terms: Erucin, Isothiocyanate, Osteoclast differentiation, Osteoclast cell fusion, DC-STAMP, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

File Description: electronic resource

Relation: https://doaj.org/toc/1756-0500

Access URL: https://doaj.org/article/e4487edba674456e89c6ef374b98e641

Application of the symbolic regression program AI-Feynman to psychology

Authors: Masato Miyazaki, Ken-Ichi Ishikawa, Ken'ichiro Nakashima, Hiroshi Shimizu, Taiki Takahashi, Nobuyuki Takahashi

Source: Frontiers in Artificial Intelligence, Vol 6 (2023)

Subject Terms: time preference, symbolic regression, AI-Feynman, hyperbolic discounting model, artificial intelligence, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frai.2023.1039438/full; https://doaj.org/toc/2624-8212

Access URL: https://doaj.org/article/d6ec97aaed134229a1126f74e645037e

Renal function in Japanese HIV-1-positive patients who switch to tenofovir alafenamide fumarate after long-term tenofovir disoproxil fumarate: a single-center observational study

Authors: Kensuke Abe, Taku Obara, Satomi Kamio, Asahi Kondo, Junji Imamura, Tatsuya Goto, Toshihiro Ito, Hiroshi Sato, Nobuyuki Takahashi

Source: AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-12 (2021)

Subject Terms: Tenofovir alafenamide fumarate, Tenofovir disoproxil fumarate, Renal function, eGFR, HIV, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1742-6405

Access URL: https://doaj.org/article/d010edacc6774f85987320816921f026

Evaluation of recombinant human erythropoietin responsiveness by measuring erythrocyte creatine content in haemodialysis patients

Authors: Shun Hasegawa, Seishi Nakamura, Tetsuro Sugiura, Yoshiaki Tsuka, Nobuyuki Takahashi, Koichiro Matsumura, Toshika Okumiya, Masato Baden, Ichiro Shiojima

Source: BMC Nephrology, Vol 22, Iss 1, Pp 1-9 (2021)

Subject Terms: Erythrocyte creatine, Erythropoiesis, Erythropoiesis stimulating agent, Haemodialysis, Renal anaemia, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2369

Access URL: https://doaj.org/article/cc95294efc7b419c9aec6a270dde364a