Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores

Authors: Yana Hrytsenko, Benjamin Shea, Michael Elgart, Nuzulul Kurniansyah, Genevieve Lyons, Alanna C. Morrison, April P. Carson, Bernhard Haring, Braxton D. Mitchell, Bruce M. Psaty, Byron C. Jaeger, C. Charles Gu, Charles Kooperberg, Daniel Levy, Donald Lloyd-Jones, Eunhee Choi, Jennifer A. Brody, Jennifer A. Smith, Jerome I. Rotter, Matthew Moll, Myriam Fornage, Noah Simon, Peter Castaldi, Ramon Casanova, Ren-Hua Chung, Robert Kaplan, Ruth J. F. Loos, Sharon L. R. Kardia, Stephen S. Rich, Susan Redline, Tanika Kelly, Timothy O’Connor, Wei Zhao, Wonji Kim, Xiuqing Guo, Yii-Der Ida Chen, The Trans-Omics in Precision Medicine Consortium, Tamar Sofer

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/322241f378754ea881e603a18375361b

Empirical evaluation of internal validation methods for prediction in large-scale clinical data with rare-event outcomes: a case study in suicide risk prediction

Authors: R Yates Coley, Qinqing Liao, Noah Simon, Susan M. Shortreed

Source: BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-10 (2023)

Subject Terms: Bootstrap, Clinical prediction, Cross-validation, Machine learning, Optimism, Random forest, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2288

Access URL: https://doaj.org/article/ce1e0b6fca324b9589c7c8bad33d9094

Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming

Authors: Magdalena L Russell, Noah Simon, Philip Bradley, Frederick A Matsen IV

Source: eLife, Vol 12 (2023)

Subject Terms: V(D)J recombination, trimming profiles, Artemis, adaptive immune receptor repertoires, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/85145; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/954f923ab0d24c51b54190fb2b2bfec9

The Impact of Time Horizon on Classification Accuracy: Application of Machine Learning to Prediction of Incident Coronary Heart Disease

Authors: Steven Simon, Divneet Mandair, Abdel Albakri, Alison Fohner, Noah Simon, Leslie Lange, Mary Biggs, Kenneth Mukamal, Bruce Psaty, Michael Rosenberg

Source: JMIR Cardio, Vol 6, Iss 2, p e38040 (2022)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://cardio.jmir.org/2022/2/e38040; https://doaj.org/toc/2561-1011

Access URL: https://doaj.org/article/4ddb1e4a5f7a4c6a8650ba9eeb5852a0

Seagull: lasso, group lasso and sparse-group lasso regularization for linear regression models via proximal gradient descent

Authors: Jan Klosa, Noah Simon, Pål Olof Westermark, Volkmar Liebscher, Dörte Wittenburg

Source: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-8 (2020)

Subject Terms: Optimization, Machine learning, High-dimensional data, R package, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12859-020-03725-w; https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/370df5c131c247cd9c7e534eb01fcdb0

'As it ever was. As it ever was.': Between the Cyclical and the Apocalyptic in The Cabin in the Woods

Authors: Noah Simon Jampol

Source: Slayage, Vol 18, Iss 1, Pp 69-87 (2020)

Subject Terms: the cabin in the woods, horror, apocalypse, joss whedon, drew goddard, jean-francois lyotard, jacques derrida, postmodern, melancholia, giambattista vico, Motion pictures, PN1993-1999

File Description: electronic resource

Relation: https://www.whedonstudies.tv/uploads/2/6/2/8/26288593/jampol_-_slayage_18.1_-_pp._69-87.pdf; https://doaj.org/toc/1546-9212

Access URL: https://doaj.org/article/3b79f3603c76411e97ec83060bf63c45

Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities

Authors: Magdalena L Russell, Aisha Souquette, David M Levine, Stefan A Schattgen, E Kaitlynn Allen, Guillermina Kuan, Noah Simon, Angel Balmaseda, Aubree Gordon, Paul G Thomas, Frederick A Matsen IV, Philip Bradley

Source: eLife, Vol 11 (2022)

Subject Terms: t cell receptor repertoire, VDJ recombination probabilities, GWAS, Artemis, TdT, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/73475; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/95bf64a4fda74d50b1793c5c3f136e61

Conflict-related intentional injuries in Baghdad, Iraq, 2003-2014: A modeling study and proposed method for calculating burden of injury in conflict.

Authors: Guy W Jensen, Riyadh Lafta, Gilbert Burnham, Amy Hagopian, Noah Simon, Abraham D Flaxman

Source: PLoS Medicine, Vol 18, Iss 8, p e1003673 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/6839b9f3d3e743c682f58ce6a33b8d22

Multidimensional analysis and detection of informative features in human brain white matter.

Authors: Adam Richie-Halford, Jason D Yeatman, Noah Simon, Ariel Rokem

Source: PLoS Computational Biology, Vol 17, Iss 6, p e1009136 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/47ba63b6a0c844f9aeeb789b64666732

An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations

Authors: Marcos H de Moraes, FoSheng Hsu, Dean Huang, Dustin E Bosch, Jun Zeng, Matthew C Radey, Noah Simon, Hannah E Ledvina, Jacob P Frick, Paul A Wiggins, S Brook Peterson, Joseph D Mougous

Source: eLife, Vol 10 (2021)

Subject Terms: Burkholderia, type vi secretion system, evolution, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/62967; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/be2fdb917a1d4d3f92780957dc64d1bf

Expression of extraocular opsin genes and light-dependent basal activity of blind cavefish

Authors: Noah Simon, Suguru Fujita, Megan Porter, Masato Yoshizawa

Source: PeerJ, Vol 7, p e8148 (2019)

Subject Terms: Hypogean, Swimming burst, Masking, Visual sensation, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/8148.pdf; https://peerj.com/articles/8148/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/97f980ecf9d54c98bf9d6937726d8079

Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features.

Authors: Craig A Magaret, David C Benkeser, Brian D Williamson, Bhavesh R Borate, Lindsay N Carpp, Ivelin S Georgiev, Ian Setliff, Adam S Dingens, Noah Simon, Marco Carone, Christopher Simpkins, David Montefiori, Galit Alter, Wen-Han Yu, Michal Juraska, Paul T Edlefsen, Shelly Karuna, Nyaradzo M Mgodi, Srilatha Edugupanti, Peter B Gilbert

Source: PLoS Computational Biology, Vol 15, Iss 4, p e1006952 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6459550?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/3019dcf47cb24cdaa070a934c89ffc44

Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells.

Authors: Minseung Choi, Diane P Genereux, Jamie Goodson, Haneen Al-Azzawi, Shannon Q Allain, Noah Simon, Stan Palasek, Carol B Ware, Chris Cavanaugh, Daniel G Miller, Winslow C Johnson, Kevin D Sinclair, Reinhard Stöger, Charles D Laird

Source: PLoS Genetics, Vol 13, Iss 11, p e1007060 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5690686?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/b967721753764a2fae9f6e07de274387

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

Authors: Noah Simon, Jerome Friedman, Trevor Hastie, Rob Tibshirani

Source: Journal of Statistical Software, Vol 39, Iss 05 (2011)

Subject Terms: survival, Cox model, lasso, elastic net, Statistics, HA1-4737

File Description: electronic resource

Relation: http://www.jstatsoft.org/v39/i05/paper; https://doaj.org/toc/1548-7660

Access URL: https://doaj.org/article/1d0633150af34fc985a62b7eeaf9a8ac

A Sound Sleep

Authors: Kolikapudi, Noah Simon

Source: Indian Literature, 2022 Jan 01. 661 (327), 33-36.

Access URL: https://www.jstor.org/stable/27277191

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On the Optimality of Nuclear-norm-based Matrix Completion for Problems with Smooth Non-linear Structure.

Authors: Yunhua Xiang¹, XIANGYH@UW.EDU, Tianyu Zhang¹, ZTY@UW.EDU, Xu Wang¹, WANGXU85@UW.EDU, Ali Shojaie¹, ASHOJAIE@UW.EDU, Noah Simon¹, NRSIMON@UW.EDU

Source: Journal of Machine Learning Research; 2023, Vol. 24, p1-38, 38p

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680 Multi-parametric assessment of the immune response to a trio immunotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma

Authors: William L Redmond, Bernard A Fox, Tarsem Moudgil, Carlo Bifulco, Walter J Urba, Christopher Paustian, Hong-Ming Hu, Traci Hilton, Tyler Hulett, Yoshinobu Koguchi, Rom S Leidner, Shawn M Jensen, Brian Piening, Matthew H Taylor, Noriko Iwamoto, Takashi Shimada, Marcus Couey, Venkatesh Rajamanickam, Brady Bernard, Yuriko Minegishi, Lessli Rushforth, Ryan Meng, Tanisha Christie, R Bryan Bell, Koji Ueda, Noah Simons, Annie Stadum, Quyen Vu, Abigail Peterson

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/b36cd8fe776f4f0abb3e8bbf236832cf