Therapeutic delivery of recombinant glucocerebrosidase enzyme-containing extracellular vesicles to human cells from Gaucher disease patients

Authors: Keatdamrong Janpipatkul, Nareerat Sutjarit, Amornrat Tangprasittipap, Tai Chaiamarit, Pawarit Innachai, Kanoknetr Suksen, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Usanarat Anurathapan, Natee Jearawiriyapaisarn, Alisa Tubsuwan, Supareak Bowornpinyo, Nithi Asavapanumas, Arthit Chairoungdua, Kanit Bhukhai, Suradej Hongeng

Source: Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)

Subject Terms: Gaucher disease, Glucocerebrosidase, Extracellular vesicles, Macrophages, Neurons, Lentiviral vector, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/59a850ee25e242c784be1f2144fdcbd3

GDNF and cAMP significantly enhance in vitro blood-brain barrier integrity in a humanized tricellular transwell model

Authors: Phongthon Kanjanasirirat, Witchuda Saengsawang, Pimonrat Ketsawatsomkron, Nithi Asavapanumas, Suparerk Borwornpinyo, Sunhapas Soodvilai, Suradej Hongeng, Sitthivut Charoensutthivarakul

Source: Heliyon, Vol 10, Iss 20, Pp e39343- (2024)

Subject Terms: Blood-brain barrier permeability, Blood-brain barrier integrity, Neurovascular unit, Drug development, In vitro blood-brain barrier, Triculture model, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024153741; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/b1084fd222ea4a389b0741271da328ba

An increase in ER stress and unfolded protein response in iPSCs-derived neuronal cells from neuronopathic Gaucher disease patients

Authors: Tanapat Pornsukjantra, Nongluk Saikachain, Nareerat Sutjarit, Arthaporn Khongkrapan, Alisa Tubsuwan, Kanit Bhukhai, Thipwimol Tim-Aroon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Subject Terms: Gaucher disease, iPSCs-derived neurons, ER stress, UPR, LSDs, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0f6e96ed824b4ccca62b25c09c125f40

Establishment of MUi030-A: A human induced pluripotent stem cell line carrying homozygous L444P mutation in the GBA1 gene to study type-3 Gaucher disease

Authors: Kitsada Kangboonruang, Tanapat Pornsukjantra, Pirut Tong-Ngam, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas, Kanit Bhukhai, Alisa Tubsuwan

Source: Stem Cell Research, Vol 73, Iss , Pp 103229- (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506123002155; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/7d6440b83bd94cfe949e746889387da2

A generation of human induced pluripotent stem cell line (MUi031-A) from a type-3 Gaucher disease patient carrying homozygous mutation on GBA1 gene

Authors: Tanapat Pornsukjantra, Kitsada Kangboonruang, Pirut Tong-Ngam, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Alisa Tubsuwan, Kanit Bhukhai, Nithi Asavapanumas

Source: Stem Cell Research, Vol 60, Iss , Pp 102698- (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506122000472; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/473a8ab9e4dd4d03953ac06bf76f6fbd

The Effects of PP2A Disruption on ER-Mitochondria Contact and Mitochondrial Functions in Neuronal-like Cells

Authors: Phaewa Chaiwijit, Kwanchanok Uppakara, Nithi Asavapanumas, Witchuda Saengsawang

Source: Biomedicines, Vol 11, Iss 4, p 1011 (2023)

Subject Terms: PP2A, ER-mitochondria contacts, MAMs, calcium, mitochondrial dynamics, Alzheimer’s disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/4/1011; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/c06132f3ca3e4e59af7a8ed71cbcbc54

Cell motility and migration as determinants of stem cell efficacy

Authors: Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer

Source: EBioMedicine, Vol 60, Iss , Pp 102989- (2020)

Subject Terms: Mesenchymal stem cells, Neural stem cells, Intranasal, Alzheimer´s disease, Oncovirolysis, Glioblastoma, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396420303650; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/50fadaeaeb26482dbe9ab2d00b7b2fef

Role of intracellular Ca2+ stores for an impairment of visual processing in a mouse model of Alzheimer's disease

Authors: Nithi Asavapanumas, Bianca Brawek, Peter Martus, Olga Garaschuk

Source: Neurobiology of Disease, Vol 121, Iss , Pp 315-326 (2019)

Subject Terms: Alzheimer's disease, Neuronal hyperactivity, Calcium stores, Impairment of visual signal processing, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996118303243; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/c3ff986c53454773a4dac4946adba7a6

Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical research

Authors: Natini Jinawath, Sacarin Bunbanjerdsuk, Maneerat Chayanupatkul, Nuttapong Ngamphaiboon, Nithi Asavapanumas, Jisnuson Svasti, Varodom Charoensawan

Source: Journal of Translational Medicine, Vol 14, Iss 1, Pp 1-13 (2016)

Subject Terms: Network biology, Systems biology, Biomedical research, Cancers, Personalized therapy, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-016-1078-3; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/b8f7b32a1aa14e9ba553a763213895a3

Potential therapeutic benefit of C1-esterase inhibitor in neuromyelitis optica evaluated in vitro and in an experimental rat model.

Authors: Lukmanee Tradtrantip, Nithi Asavapanumas, Puay-Wah Phuan, A S Verkman

Source: PLoS ONE, Vol 9, Iss 9, p e106824 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4156393?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/83f3d25240314191980d6571390a9f9d

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