Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis

Authors: Nischalke, H.D., Berger, C., Aldenhoff, K., Thyssen, L., Gentemann, M., Grünhage, F., Lammert, F., Nattermann, J., Sauerbruch, T., Spengler, U., Appenrodt, B.

Source: In Journal of Hepatology November 2011 55(5):1010-1016

FRI-175 - A functional ATG16L1 (T300A) gene variant is associated with increased risk for hepatocellular carcinoma in cirrhosis

Authors: Reuken, P., Lutz, P., Casper, M., Al-Herwi, E., Stallmach, A., Lammert, F., Nischalke, H.D., Bruns, T.

Source: In Journal of Hepatology April 2018 68 Supplement 1:S439-S440

P0471 : NKp46 and trail are the major NK cell receptors involved in anti-HCV activity of NK cells in vitro

Authors: Krämer, B., Zwank, C., Glässner, A., Kokordelis, P., Wolter, F., Kaczmarek, D., Lutz, P., Göser, F., Nischalke, H.D., Strassburg, C.P., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology April 2015 62 Supplement 2:S490-S490

P0217 : Use of beta-blockers at the onset of spontaneous bacterial peritonitis may be beneficial due to modulation of immune response

Authors: Lutz, P., Nischalke, H.D., Kraemer, B., Langhans, B., Schlabe, S., Nattermann, J., Hoerauf, A., Strassburg, C.P., Spengler, U.

Source: In Journal of Hepatology April 2015 62 Supplement 2:S387-S388

LO6 : A two-stage genome-wide association study identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Authors: Buch, S., Stickel, F., Trépo, E., Way, M., Herrmann, A., Nischalke, H.D., Brosch, M., Rosendahl, J., Berg, T., Fischer, J., Ridinger, M., Rietschel, M., McQuillin, A., Frank, J., Kiefer, F., Schreiber, S., Lieb, W., Soyka, M., Datz, C., Schmelz, R., Brückner, S., Wodarz, N., Deviére, J., Clumeck, N., Sarrazin, C., Lammert, F., Gustot, T., Deltenre, P., Völtzke, H., Lerch, M.M., Mayerle, J., Eyer, F., Schafmayer, C., Cichon, S., Nöthen, M.M., Nothnagel, M., Ellinghaus, D., Franke, A., Zopf, S., Hellerbrand, C., Moreno, C., Franchimont, D., Morgan, M.Y., Hampe, J.

Source: In Journal of Hepatology April 2015 62 Supplement 2:S260-S261

P311 A COMMON POLYMORPHISM IN THE NCAN GENE IS ASSOCIATED WITH HEPATOCELLULAR CARCINOMA IN ALCOHOLIC LIVER DISEASE

Authors: Nischalke, H.D., Lutz, P., Krämer, B., Söhne, J., Müller, T., Rosendahl, J., Fischer, J., Berg, T., Soyka, M., Nattermann, J., Sauerbruch, T., Strassburg, C.P., Stickel, F., Spengler, U.

Source: In Journal of Hepatology April 2014 60(1) Supplement:S170-S170

P143 ACTIVATED MONOCYTES EXPRESS IFN-λ RECEPTOR 1 AND EFFECTIVELY TRIGGER IFN-γ SECRETION OF NK CELLS AFTER STIMULATION WITH IFN-λ

Authors: Krämer, B., Sastre Turrión, B.S., Glässner, A., Eisenhardt, M., Wolter, F., Kokordelis, P., Nischalke, H.D., Strassburg, C.P., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology April 2014 60(1) Supplement:S113-S113

782 IMPAIRED CD4+ T CELL-MEDIATED STIMULATION OF NK CELL ANTI-FIBROTIC ACTIVITY MAY CONTRIBUTE TO ACCELERATED PROGRESSION TOWARDS HCV-ASSOCIATED LIVER FIBROSIS IN HIV/HCV CO-INFECTED PATIENTS

Authors: Glässner, A., Eisenhardt, M., Krämer, B., Wolter, F., Kokordelis, P., Sibbing, B., Nischalke, H.D., Rockstroh, J., Sauerbruch, T., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology April 2012 56 Supplement 2:S306-S307

778 THE CD56BRIGHTCXCR3(+) PHENOTYPE CHARACTERIZES A DISTINCT NK CELL SUBSET WITH ANTI-FIBROTIC POTENTIAL THAT SHOWS DYS-REGULATED ACTIVITY IN HEPATITIS C

Authors: Eisenhardt, M., Glässner, A., Krämer, B., Körner, C., Sibbing, B., Kokordelis, P., Nischalke, H.D., Sauerbruch, T., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology April 2012 56 Supplement 2:S305-S305

324 TLR-2 ACTIVATION WITH HCV CORE AND NS3 ENHANCES PROANGIOGENIC DIFFERENTIATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS

Authors: Wolter, F., Nischalke, H.D., Luda, C., Eisenhardt, M., Glassner, A., Kramer, B., Kokordelis, P., Sauerbruch, T., Nattermann, J., Spengler, U.

Source: In Journal of Hepatology April 2012 56 Supplement 2:S132-S132

127 THE ACTIVATING NK CELL RECEPTOR NKP46 MAY BE INVOLVED IN ANTI-FIBROTIC ACTIVITY OF NK CELLS IN CHRONIC HEPATITIS C

Authors: Kramer, B., Körner, C., Zwank, C., Eisenhardt, M., Glassner, A., Kokordelis, P., Wolter, F., Nischalke, H.D., Sauerbruch, T., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology April 2012 56 Supplement 2:S55-S56

1345 INTERACTION BETWEEN IL28B CCR5Δ32, AND HCV PERSISTENCE WITH GBV-C VIREMIA AND SYMPTOMS DURING ACUTE INFECTION

Authors: Tenckhoff, S., Wiegand, J., Patel, K., Wiese, M., Tenckhoff, H., Nischalke, H.D., Kullig, U., Gobel, U., Capka, E., Schiefte, I., Güthoff, W., Grüngreiff, K., König, I., Spengler, U., McCarthy, J.J., Thompson, A.J., McHutchison, J.G., Timm, J., Viazov, S., Nattermann, J., Tillmann, H.

Source: In Journal of Hepatology March 2011 54 Supplement 1:S531-S531

232 TRAIL RECEPTOR I POLYMORPHISMS C626G AND A638C ARE ASSOCIATED WITH AN INCREASED RISK FOR THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA (HCC) IN HCV-INFECTED PATIENTS

Authors: Körner, C., Riesner, K., Krämer, B., Eisenhardt, M., Müller, T., Berg, T., Sauerbruch, T., Nattermann, J., Spengler, U., Nischalke, H.D.

Source: In Journal of Hepatology March 2011 54 Supplement 1:S96-S96

1172 GENETIC VARIATION IN IL28B RS 12979860 AND RESPONSE TO HCV-SPECIFIC TREATMENT IN HCV/HIV CO-INFECTED PATIENTS

Authors: Nischalke, H.D., Vogel, M., Michalk, M., Mauss, S., Baumgarten, A., Naumann, U., Stellbrink, H.-J., Danta, M., Tural, C., Bruno, R., Krämer, B., Körner, C., Schulte, D., Eisenhardt, M., Glässner, A., Sauerbruch, T., Rockstroh, J.K., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology 2010 52 Supplement 1:S453-S453

884 CXCL1 RS4074 POLYMORPHISM INFLUENCES THE SUSCEPTIBILITY TO HEPATOCELLULAR CARCINOMA

Authors: Nischalke, H.D., Coenen, M., Berger, C., Müller, T., Berg, T., Luda, C., Krämer, B., Schulte, D., Körner, C., Nattermann, J., Sauerbruch, T., Spengler, U.

Source: In Journal of Hepatology 2010 52 Supplement 1:S344-S344

440 NKP46 HIGH AND NKP46 DIM EXPRESSION DEFINES PHENOTYPICALLY AND FUNCTIONALLY DIFFERENT HUMAN NK CELL SUBSETS THAT ARE ALTERED IN CHRONIC HEPATITIS C

Authors: Körner, C., Krämer, B., Schulte, D., Zwank, C., Eisenhardt, M., Glässner, A., Nischalke, H.D., Sauerbruch, T., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology 2010 52 Supplement 1:S178-S178

125 IL28B POLYMORPHISM IS ASSOCIATED WITH JAUNDICE DURING ACUTE HCV INFECTION AND IS A STRONG PREDICTOR FOR SPONTANEOUS CLEARANCE IN THE PROSPECTIVE GERMAN ANTI-D COHORT

Authors: Tillmann, H., Thompson, A.J., Patel, K., Wiese, M., Tenckhoff, H., Nischalke, H.D., Kullig, U., Goebel, U., Capka, E., Wiegand, J., Schiefke, I., Spengler, U., McCarthy, J., Shianna, K., Goldstein, D.B., McHutchison, J.G., Timm, J., Nattermann, J.

Source: In Journal of Hepatology 2010 52 Supplement 1:S56-S56

894 HLA-E-RESTRICTED RECOGNITION OF A HCV- DERIVED PEPTIDE BY HUMAN CD8(+) CYTOLYTIC T LYMPHOCYTES

Authors: Schulte, D., Kraemer, B., Koerner, C., Michalk, M., Nischalke, H.D., Sauerbruch, T., Spengler, U., Nattermann, J.

Source: In Journal of Hepatology 2009 50 Supplement 1:S325-S325

816 THE TGF-β HIGH PRODUCER GENOTYPE IS ASSOCIATED WITH RESPONSE TO HCV-SPECIFIC THERAPY IN HIV-POSITIVE PATIENTS WITH ACUTE HEPATITIS C

Authors: Nattermann, J., Vogel, M., Nischalke, H.D., Danta, M., Ahlenstiel, G., Michalk, M., Sauerbruch, T., Rockstroh, J., Spengler1 for the Kompetenznetz Hepatitis, U.

Source: In Journal of Hepatology 2008 48 Supplement 2:S305-S306

625 POLYMORPHISMS IN TOLL-LIKE RECEPTORS 1 AND 2 ARE NOT ASSOCIATED WITH HEPATOCELLULAR CARCINOMA IN CHRONIC HEPATITIS C

Authors: Nischalke, H.D., Reich, B., Aldenhoff, K., Nattermann, J., Sauerbruch, T., Spengler, U.

Source: In Journal of Hepatology 2008 48 Supplement 2:S232-S233