Efficacy of amivantamab, a bi-specific antibody targeting EGFR and MET, in ALK-rearranged non-small-cell lung cancer cell lines

Authors: Nishi, Tatsuya ^a, Morita, Ayako ^b, Hara, Naofumi ^b, Makimoto, Go ^b, Ninomiya, Kiichiro ^c, Fujii, Masanori ^b, Rai, Kammei ^d, Ohashi, Kadoaki ^b, Hotta, Katsuyuki ^d, Tabata, Masahiro ^e, Togashi, Yosuke ^{b, f, g}, Maeda, Yoshinobu ^a, Ichihara, Eiki ^{e, ⁎}

Source: In Lung Cancer March 2025 201

A Single-Arm Phase 2 Study of Sotorasib Plus Carboplatin/Pemetrexed in Patients With Advanced Nonsquamous NSCLC With KRAS G12C Mutation (WJOG14821L, SCARLET)

Authors: Akamatsu, Hiroaki ^{a, ∗}, Sakata, Shinya ^b, Azuma, Koichi ^c, Yoshioka, Hiroshige ^d, Uemura, Takehiro ^e, Tsuchiya-Kawano, Yuko ^f, Esumi, Seiya ^g, Kurosaki, Takashi ^h, Sato, Yuki ⁱ, Sakamoto, Tomohiro ^j, Ninomiya, Kiichiro ^k, Toyozawa, Ryo ^l, Yoneshima, Yasuto ^m, Shukuya, Takehito ⁿ, Kozuki, Toshiyuki ^o, Watanabe, Kana ^p, Daga, Haruko ^q, Kato, Terufumi ^r, Takahashi, Toshiaki ^s, Osuga, Mitsuo ^t, Koh, Yasuhiro ^{a, t}, Morita, Satoshi ^u, Yamamoto, Nobuyuki ^a

Source: In Journal of Thoracic Oncology January 2025

Continuation of osimertinib in EGFR-mutant non-small-cell lung cancer patients bearing CNS metastasis (EPONA study)

Authors: Okuma, Yusuke, Nomura, Shogo, Ninomiya, Kiichiro, Gyotoku, Hiroshi, Murakami, Shuji, Kogure, Yoshihito, Harada, Daijiro, Okishio, Kyoichi, Okamoto, Hiroaki, Goto, Yasushi

Source: Future oncology. 19(22):1515-1521

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192022897.0x000001&indx=1&recIds=ETOCvdc_100192022897.0x000001

PD-1 blockade augments CD8+ T cell dependent antitumor immunity triggered by Ad-SGE-REIC in Egfr-mutant lung cancer

Authors: Nakasuka, Takamasa, Ohashi, Kadoaki, Nishii, Kazuya, Hirabae, Atsuko, Okawa, Sachi, Tomonobu, Nahoko, Takada, Kenji, Ando, Chihiro, Watanabe, Hiromi, Makimoto, Go, Ninomiya, Kiichiro, Fujii, Masanori, Kubo, Toshio, Ichihara, Eiki, Hotta, Katsuyuki, Tabata, Masahiro, Kumon, Hiromi, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: Lung cancer. 178:1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186488402.0x000001&indx=1&recIds=ETOCvdc_100186488402.0x000001

Safety of anti‐SARS‐CoV‐2 messenger RNA vaccine in lung cancer patients undergoing anticancer chemotherapy: A multicenter, prospective, observational, patient‐reported outcome study

Authors: Harada, Daijiro, Tamura, Tomoki, Ninomiya, Kiichiro, Kubo, Toshio, Kuyama, Shoichi, Tachibana, Sayaka, Inoue, Koji, Chikamori, Kenichi, Kudo, Kenichiro, Ochi, Nobuaki, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: Thoracic cancer. 14(3):231-236

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172701210.0x000001&indx=1&recIds=ETOCvdc_100172701210.0x000001

Multicenter, Retrospective Study to Evaluate Necitumumab Plus Cisplatin and Gemcitabine After Immune Checkpoint Inhibitors in Advanced Squamous Cell Lung Cancer in Japan: The NINJA Study

Authors: Murata, Yasunori, Tanzawa, Shigeru, Misumi, Toshihiro, Yoshioka, Hiroshige, Miyauchi, Eisaku, Ninomiya, Kiichiro, Takeshita, Masafumi, Ito, Kensaku, Okamoto, Tatsuro, Sugawara, Shunichi, Kawashima, Yosuke, Hashimoto, Kazuki, Mori, Masahide, Miyanaga, Akihiko, Hayashi, Anna, Tanaka, Hisashi, Honda, Ryoichi, Nojiri, Masafumi, Sato, Yuki, Hata, Akito, Masuda, Ken, Kozuki, Toshiyuki, Kawamura, Takahisa, Suzuki, Takuji, Yamaguchi, Teppei, Asada, Kazuhiro, Tetsumoto, Satoshi, Tanaka, Hiroshi, Watanabe, Satoshi, Umeda, Yukihiro, Yamaguchi, Kakuhiro, Kuyama, Shoichi, Tsuruno, Kosuke, Misumi, Yuki, Kuraishi, Hiroshi, Yoshihara, Ken, Nakao, Akira, Kubo, Akihito, Yokoyama, Toshihiko, Watanabe, Kana, Seki, Nobuhiko

Source: In JTO Clinical and Research Reports December 2023 4(12)

Significance of the comprehensive geriatric assessment in the administration of chemotherapy to older adults with cancer: Recommendations by the Japanese Geriatric Oncology Guideline Committee

Authors: Ninomiya, Kiichiro, Inoue, Daisuke, Sugimoto, Ken, Tanaka, Chie, Murofushi, Keiko, Okuyama, Toru, Watanuki, Shigeaki, Imamura, Chiyo K., Sakai, Daisuke, Sakurai, Naomi, Watanabe, Kiyotaka, Tamura, Kazuo, Saeki, Toshiaki, Ishiguro, Hiroshi

Source: In Journal of Geriatric Oncology June 2023 14(5)

Real-World Data Analysis of Pembrolizumab Monotherapy for NSCLC Using Japanese Postmarketing All-Case Surveillance Data

Authors: Terai, Hideki, Soejima, Kenzo, Shimokawa, Asanao, Horinouchi, Hidehito, Shimizu, Junichi, Hase, Tetsunari, Kanemaru, Ryota, Watanabe, Kana, Ninomiya, Kiichiro, Aragane, Naoko, Yanagitani, Noriko, Sakata, Yoshihiko, Seike, Masahiro, Fujimoto, Daichi, Kasajima, Masashi, Kubo, Akihito, Kusumoto, Sojiro, Oyamada, Yoshitaka, Fujiwara, Keiichi, Mori, Masahide, Hashimoto, Midori, Shingyoji, Masato, Kodani, Masahiro, Sakamoto, Jin, Agatsuma, Toshihiko, Kashiwabara, Kosuke, Inomata, Minehiko, Tachihara, Motoko, Tanaka, Kazuhisa, Hayashihara, Kenji, Koyama, Nobuyuki, Matsui, Kaoru, Minato, Koichi, Jingu, Daisuke, Sakashita, Hiroyuki, Hara, Satoshi, Naito, Tomoyuki, Okada, Asuka, Tanahashi, Masayuki, Sato, Yuki, Asano, Koichiro, Takeda, Takayuki, Nakazawa, Kensuke, Harada, Toshiyuki, Shibata, Kazuhiko, Kato, Tatsuo, Miyaoka, Etsuo, Yoshino, Ichiro, Gemma, Akihiko, Mitsudomi, Tetsuya

Source: In JTO Clinical and Research Reports November 2022 3(11)

Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational study

Authors: Tamura, Tomoki, Ninomiya, Kiichiro, Kubo, Toshio, Kuyama, Shoichi, Tachibana, Sayaka, Inoue, Koji, Chikamori, Kenichi, Kudo, Kenichiro, Ochi, Nobuaki, Harada, Daijiro, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: Thoracic cancer. 13(3):453-459

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141616631.0x000001&indx=1&recIds=ETOCvdc_100141616631.0x000001

Successful and Prompt Treatment with Tepotinib for Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation Combined with Lung Abscess Formation: A Case Report

Authors: Makimoto, Go, Shimonishi, Atsushi, Ohashi, Kadoaki, Ninomiya, Kiichiro, Higo, Hisao, Kato, Yuka, Fujii, Masanori, Kubo, Toshio, Ichihara, Eiki, Hotta, Katsuyuki, Tabata, Masahiro, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: Case reports in oncology. 15(2):494-498

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100160784078.0x000001&indx=1&recIds=ETOCvdc_100160784078.0x000001

Clinical impact of hypomagnesemia induced by necitumumab plus cisplatin and gemcitabine treatment in patients with advanced lung squamous cell carcinoma: a subanalysis of the NINJA study.

Authors: Tanzawa, Shigeru, Yoshioka, Hiroshige, Misumi, Toshihiro, Miyauchi, Eisaku, Ninomiya, Kiichiro, Murata, Yasunori, Takeshita, Masafumi, Kinoshita, Fumihiko, Fujishita, Takatoshi, Sugawara, Shunichi, Kawashima, Yosuke, Hashimoto, Kazuki, Mori, Masahide, Miyanaga, Akihiko, Hayashi, Anna, Tanaka, Hisashi, Honda, Ryoichi, Nojiri, Masafumi, Sato, Yuki, Hata, Akito

Source: Therapeutic Advances in Medical Oncology; 2/14/2025, p1-16, 16p

Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma.

Authors: Inukai-Motokura, Yumi, Ninomiya, Kiichiro, Baba, Takahiro, Omori, Hiroki, Takeguchi, Tetsuya, Uno, Mari, Ayada, Yoshiyuki, Tanaka, Takehiro, Maeda, Yoshinobu, Ohashi, Kadoaki

Source: International Cancer Conference Journal; Jan2025, Vol. 14 Issue 1, p60-63, 4p

Comparison of bronchoscopy and computed tomography-guided needle biopsy for re-biopsy in non-small cell lung cancer patients

Authors: Kano, Hirohisa, Kubo, Toshio, Ninomiya, Kiichiro, Ichihara, Eiki, Ohashi, Kadoaki, Rai, Kammei, Hotta, Katsuyuki, Tabata, Masahiro, Hiraki, Takao, Kanazawa, Susumu, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: In Respiratory Investigation March 2021 59(2):240-246

Japanese Lung Cancer Society Guidelines for Stage IV NSCLC With EGFR Mutations

Authors: Ninomiya, Kiichiro, Teraoka, Shunsuke, Zenke, Yoshitaka, Kenmotsu, Hirotsugu, Nakamura, Yukiko, Okuma, Yusuke, Tamiya, Akihiro, Nosaki, Kaname, Morise, Masahiro, Aokage, Keiju, Oya, Yuko, Kozuki, Toshiyuki, Sakamoto, Tomohiro, Tanaka, Kentaro, Tanaka, Hisashi, Tanizaki, Junko, Miura, Satoru, Mizutani, Hideaki, Miyauchi, Eisaku, Yamaguchi, Ou, Ebi, Noriyuki, Goto, Yasushi, Sasaki, Takaaki, Daga, Haruko, Morita, Satoshi, Yamanaka, Takeharu, Amano, Shinsuke, Hasegawa, Kazuo, Imamura, Chiyo K., Suzuki, Kenichi, Nakajima, Kazuko, Nishimoto, Hitomi, Oizumi, Satoshi, Hida, Toyoaki, Hotta, Katsuyuki, Takiguchi, Yuichi

Source: In JTO Clinical and Research Reports January 2021 2(1)

VEGFR2 blockade augments the effects of tyrosine kinase inhibitors by inhibiting angiogenesis and oncogenic signaling in oncogene‐driven non‐small‐cell lung cancers

Authors: Watanabe, Hiromi, Ichihara, Eiki, Kayatani, Hiroe, Makimoto, Go, Ninomiya, Kiichiro, Nishii, Kazuya, Higo, Hisao, Ando, Chihiro, Okawa, Sachi, Nakasuka, Takamasa, Kano, Hirohisa, Hara, Naofumi, Hirabae, Atsuko, Kato, Yuka, Ninomiya, Takashi, Kubo, Toshio, Rai, Kammei, Ohashi, Kadoaki, Hotta, Katsuyuki, Tabata, Masahiro, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: Cancer science. 112(5):1853-1864

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121022783.0x000001&indx=1&recIds=ETOCvdc_100121022783.0x000001

Response to Imatinib in a Patient With Gastric Adenocarcinoma With KIT Q556_K558 In-Frame Deletion: A Case Report.

Authors: Ninomiya, Kiichiro¹ (AUTHOR) kiichiro_nino@okayama-u.ac.jp, Ennishi, Daisuke¹ (AUTHOR), Okamoto, Kunio² (AUTHOR), Ando, Midori³ (AUTHOR), Nakamura, Satoko³ (AUTHOR), Tomida, Shuta¹ (AUTHOR), Ayada, Yoshiyuki⁴ (AUTHOR), Makimoto, Go⁵ (AUTHOR), Ichihara, Eiki⁵ (AUTHOR), Okita, Natsuko⁶ (AUTHOR), Toyooka, Shinichi¹ (AUTHOR), Maeda, Yoshinobu⁷ (AUTHOR), Tabata, Masahiro⁵ (AUTHOR)

Source: JCO Precision Oncology. 12/1/2024, Vol. 8, p1-5. 5p.

Subject Terms: *EPIDERMAL growth factor receptors, *PROTEIN-tyrosine kinase inhibitors, *GAIN-of-function mutations, *CANCER patients, *DELETION mutation, *HEAD & neck cancer, *CHONDROSARCOMA

Impact of HER2 expression on EGFR-TKI treatment outcomes in lung tumors harboring EGFR mutations: A HER2-CS study subset analysis

Authors: Ohashi, Kadoaki, Ninomiya, Kiichiro, Yoshioka, Hiroshige, Bessho, Akihiro, Shibayama, Takuo, Aoe, Keisuke, Ishikawa, Nobuhisa, Kozuki, Toshiyuki, Kawai, Haruyuki, Kuyama, Shoichi, Miyoshi, Seigo, Fujitaka, Kazunori, Obata, Hideto, Tsubata, Yukari, Awaya, Yoshikazu, Inoue, Masaaki, Inoue, Koji, Horita, Naokatsu, Yanai, Hiroyuki, Hotta, Katsuyuki ^*, Kiura, Katsuyuki

Source: In Lung Cancer December 2020 150:83-89

EGFR-TKI acquired resistance in lung cancers harboring EGFR mutations in immunocompetent C57BL/6J mice

Authors: Higo, Hisao, Ohashi, Kadoaki, Makimoto, Go, Nishii, Kazuya, Kudo, Kenichiro, Kayatani, Hiroe, Watanabe, Hiromi, Kano, Hirohisa, Ninomiya, Kiichiro, Hotta, Katsuyuki, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: In Lung Cancer October 2019 136:86-93

Programmed cell death-ligand 1 expression and efficacy of cisplatin-based chemotherapy in lung cancer: A sub-analysis of data from the two Okayama Lung Cancer Study Group prospective feasibility studies

Authors: Nishii, Kazuya, Hotta, Katsuyuki, Ninomiya, Kiichiro, Kato, Yuka, Ichihara, Eiki, Ohashi, Kadoaki, Ninomiya, Takashi, Kubo, Toshio, Rai, Kammei, Tabata, Masahiro, Maeda, Yoshinobu, Kiura, Katsuyuki

Source: In Respiratory Investigation September 2019 57(5):460-465

A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY)

Authors: Gemba, K., Ikeda, G., Yasugi, M., Kurimoto, E., Nakano, K., Moritaka, T., Inoue, K., Miyoshi, S., Hamaguchi, N., Ito, R., Sano, Y., Takata, I., Mitani, A., Nishisaka, T., Shoda, H., Nishida, A., Tamamoto, S., Fujitaka, K., Masuda, T., Miyamoto, S., Hattori, N., Sugimoto, K., Fujii, S., Ueda, Y., Sakugawa, M., Fukamatsu, N., Ogata, Y., Bandoh, S., Kanaji, N., Takigawa, N., Yamane, H., Ochi, N., Honda, Y., Oka, M., Kittaka, M., Kubota, T., Yokoyama, A., Yokoyama, T., Sato, E., Shiota, Y., Horita, N., Kanematsu, T., Awaya, Y., Nakamasu, A., Murakami, I., Kuyama, S., Kudo, K., Tamura, T., Umeno, T., Morichika, D., Fujiwara, K., Sato, K., Harada, D., Nogami, N., Nishii, K., Fuchimoto, Y., Kishimoto, T., Kawai, H., Watanabe, K., Tokumo, K., Isobe, T., Tsubata, Y., Inoue, M., Ichikawa, H., Nishioka, Y., Hanibuchi, M., Goto, H., Sumikawa, T., Kodani, M., Suyama, H., Makino, H., Kinosita, N., Shimizu, E., Obata, H., Ikegami, H., Chikamori, K., Maeda, T., Kishino, T., Kamei, H., Ueoka, H., Kunihiro, Y., Kobayashi, T., Ueda, K., Hayashi, M., Kamiya, M., Murakami, J., Sato, A., Ichihara, E., Kubo, T., Ninomiya, T., Hirata, T., Minami, D., Kato, Y., Higo, H., Makimoto, G., Toyota, Y., Oda, N., Nakanishi, M., Kayatani, H., Senoo, S., Kano, H., Watanabe, H., Ando, T., Nakasuka, T., Hara, N., Itano, J., Nakashima, H., Tabata, M., Ninomiya, Kiichiro, Hata, Tae, Yoshioka, Hiroshige, Ohashi, Kadoaki, Bessho, Akihiro, Hosokawa, Shinobu, Ishikawa, Nobuhisa, Yamasaki, Masahiro, Shibayama, Takuo, Aoe, Keisuke, Kozuki, Toshiyuki, Harita, Shingo, Ueda, Yutaka, Murakami, Toshi, Fujimoto, Nobukazu, Yanai, Hiroyuki, Toyooka, Shinichi, Takata, Minoru, Hotta, Katsuyuki, Kiura, Katsuyuki

Source: In Chest August 2019 156(2):357-366