Assigning Transcriptomic Subtypes to Chronic Lymphocytic Leukemia Samples Using Nanopore RNA-Sequencing and Self-Organizing Maps.

Authors: Arakelyan, Arsen, Sirunyan, Tamara, Khachatryan, Gisane, Hakobyan, Siras, Minasyan, Arpine, Nikoghosyan, Maria, Hakobyan, Meline, Chavushyan, Andranik, Martirosyan, Gevorg, Hakobyan, Yervand, Binder, Hans

Source: Cancers; Mar2025, Vol. 17 Issue 6, p964, 15p

Subject Terms: CHRONIC lymphocytic leukemia, CLUSTER analysis (Statistics), T cells, RESEARCH funding, POLYMERASE chain reaction, CELL proliferation, CELL cycle, DESCRIPTIVE statistics, RNA, SUPPORT vector machines, GENE expression profiling, NANOTECHNOLOGY, DNA repair, MACHINE learning, GENETIC techniques, INFLAMMATION, DATA analysis software, SEQUENCE analysis, ALGORITHMS, PHENOTYPES, REGRESSION analysis, B cells

Unveiling Iso- and Aniso-Hydric Disparities in Grapevine—A Reanalysis by Transcriptome Portrayal Machine Learning.

Authors: Konecny, Tomas, Asatryan, Armine, Nikoghosyan, Maria, Binder, Hans

Source: Plants (2223-7747); Sep2024, Vol. 13 Issue 17, p2501, 32p

Subject Terms: WATER shortages, CLIMATE change, SELF-organizing maps, GENE expression, MACHINE learning

Machine learning extracts marks of thiamine's role in cold acclimation in the transcriptome of Vitis vinifera.

Authors: Konecny, Tomas, Nikoghosyan, Maria, Binder, Hans

Source: Frontiers in Plant Science; 2023, p1-12, 12p

Subject Terms: VITIS vinifera, VITAMIN B1, TEMPERATURE control, GENE regulatory networks, CLIMATE change, MACHINE learning, GENE expression

Molecular Analysis of SARS-CoV-2 Lineages in Armenia.

Authors: Avetyan, Diana, Hakobyan, Siras, Nikoghosyan, Maria, Ghukasyan, Lilit, Khachatryan, Gisane, Sirunyan, Tamara, Muradyan, Nelli, Zakharyan, Roksana, Chavushyan, Andranik, Hayrapetyan, Varduhi, Hovhannisyan, Anahit, Mohamed Bakhash, Shah A., Jerome, Keith R., Roychoudhury, Pavitra, Greninger, Alexander L., Niazyan, Lyudmila, Davidyants, Mher, Melik-Andreasyan, Gayane, Sargsyan, Shushan, Nersisyan, Lilit

Source: Viruses (1999-4915); May2022, Vol. 14 Issue 5, p1074-1074, 14p

Subject Terms: SARS-CoV-2, NUCLEOTIDE sequencing, SARS-CoV-2 Omicron variant, DIAGNOSTIC use of polymerase chain reaction, FUNCTIONAL analysis

Geographic Terms: ARMENIA

Transcriptome Patterns of BRCA1 - and BRCA2 - Mutated Breast and Ovarian Cancers.

Authors: Arakelyan, Arsen, Melkonyan, Ani, Hakobyan, Siras, Boyarskih, Uljana, Simonyan, Arman, Nersisyan, Lilit, Nikoghosyan, Maria, Filipenko, Maxim, Binder, Hans

Source: International Journal of Molecular Sciences; Feb2021, Vol. 22 Issue 3, p1266-1266, 1p

Subject Terms: BREAST cancer, OVARIAN cancer, BRCA genes, PHENOTYPES, SELF-organizing maps, SOMATIC mutation, P53 antioncogene

SOMmelier—Intuitive Visualization of the Topology of Grapevine Genome Landscapes Using Artificial Neural Networks.

Authors: Nikoghosyan, Maria^1,2 (AUTHOR) m_nikoghosyan@mb.sci.am, Schmidt, Maria³ (AUTHOR) schmidt@izbi.uni-leipzig.de, Margaryan, Kristina^4,5 (AUTHOR) kristinamargaryan@ysu.am, Loeffler-Wirth, Henry³ (AUTHOR) wirth@izbi.uni-leipzig.de, Arakelyan, Arsen^1,2 (AUTHOR) aarakelyan@sci.am, Binder, Hans³ (AUTHOR) binder@izbi.uni-leipzig.de

Source: Genes. Jul2020, Vol. 11 Issue 7, p817. 1p.

Subject Terms: *ARTIFICIAL neural networks, *TABLE grapes, *GRAPES, *GENOMES, *VITIS vinifera, *SELF-organizing maps, *CLIMBING plants

Geographic Terms: MAGHREB (North Africa), WESTERN Europe

Transcriptome-Guided Drug Repositioning.

Authors: Arakelyan, Arsen, Nersisyan, Lilit, Nikoghosyan, Maria, Hakobyan, Siras, Simonyan, Arman, Hopp, Lydia, Loeffler-Wirth, Henry, Binder, Hans

Source: Pharmaceutics; Dec2019, Vol. 11 Issue 12, p677-677, 1p

Subject Terms: INFLAMMATORY bowel diseases, INHALERS, CROHN'S disease, JUVENILE idiopathic arthritis, OBSTRUCTIVE lung diseases, ULCERATIVE colitis, SELF-organizing maps, SARCOIDOSIS