Construction and evaluation of an α-particle-irradiation exposure apparatus

Authors: Nikitaki, Zacharenia, Choulilitsa, Evangelia, Kalospyros, Spyridon A., Kaisaridi, Sofia, Terzoudi, Georgia I., Kokkoris, Mike, Georgakilas, Alexandros G.

Source: International journal of radiation biology. 97(10):1404-1416

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Role of DNA damage and repair in radiation cancer therapy: a current update and a look to the future

Authors: Liu, Jingya, Bi, Kun, Yang, Run, Li, Hongxia, Nikitaki, Zacharenia, Chang, Li

Source: International journal of radiation biology. 96(11):1329-1338

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110752451.0x000001&indx=1&recIds=ETOCvdc_100110752451.0x000001

Clustered DNA Damage Patterns after Proton Therapy Beam Irradiation Using Plasmid DNA.

Authors: Souli, Maria P.^1,2 (AUTHOR), Nikitaki, Zacharenia^1,2 (AUTHOR), Puchalska, Monika¹ (AUTHOR), Brabcová, Kateřina Pachnerová³ (AUTHOR), Spyratou, Ellas⁴ (AUTHOR), Kote, Panagiotis² (AUTHOR), Efstathopoulos, Efstathios P.⁴ (AUTHOR), Hada, Megumi⁵ (AUTHOR), Georgakilas, Alexandros G.² (AUTHOR) alexg@mail.ntua.gr, Sihver, Lembit^1,3 (AUTHOR) alexg@mail.ntua.gr

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p15606. 21p.

Subject Terms: *PROTON therapy, *DNA damage, *LINEAR energy transfer, *IRRADIATION, *ATOMIC force microscopy, *DNA

Integrating plant and animal biology for the search of novel DNA damage biomarkers

Authors: Nikitaki, Zacharenia, Holá, Marcela, Donà, Mattia, Pavlopoulou, Athanasia, Michalopoulos, Ioannis, Angelis, Karel J., Georgakilas, Alexandros G., Macovei, Anca, Balestrazzi, Alma

Source: In Mutation Research-Reviews in Mutation Research January-March 2018 775:21-38

Non-Targeted Effects of Synchrotron Radiation: Lessons from Experiments at the Australian and European Synchrotrons.

Authors: Fernandez-Palomo, Cristian¹, cristian.fernandez@unibe.ch, Nikitaki, Zacharenia², znikitaki@mail.ntua.gr, Djonov, Valentin¹, valentin.djonov@unibe.ch, Georgakilas, Alexandros G.², alexg@mail.ntua.gr, Martin, Olga A.^1,3,4, alexg@mail.ntua.gr

Source: Applied Sciences (2076-3417); Feb2022, Vol. 12 Issue 4, p2079, 20p

Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?

Authors: Nikitaki, Zacharenia, Nikolov, Vladimir, Mavragani, Ifigeneia V., Plante, Ianik, Emfietzoglou, Dimitris, Iliakis, George, Georgakilas, Alexandros G.

Source: In Radiation Physics and Chemistry November 2016 128:26-35

Systemic mechanisms and effects of ionizing radiation: A new ⿿old⿿ paradigm of how the bystanders and distant can become the players

Authors: Nikitaki, Zacharenia, Mavragani, Ifigeneia V., Laskaratou, Danae A., Gika, Violeta, Moskvin, Vadim P., Theofilatos, Konstantinos, Vougas, Konstantinos, Stewart, Robert D., Georgakilas, Alexandros G.

Source: In Seminars in Cancer Biology June 2016 37-38:77-95

Radiation triggering immune response and inflammation

Authors: Hekim, Nezih, Cetin, Zafer, Nikitaki, Zacharenia, Cort, Aysegul, Saygili, Eyup Ilker ^*

Source: In Cancer Letters 28 November 2015 368(2):156-163

Emerging molecular networks common in ionizing radiation, immune and inflammatory responses by employing bioinformatics approaches

Authors: Georgakilas, Alexandros G., Pavlopoulou, Athanasia, Louka, Maria, Nikitaki, Zacharenia, Vorgias, Constantinos E., Bagos, Pantelis G., Michalopoulos, Ioannis ^*

Source: In Cancer Letters 28 November 2015 368(2):164-172

Monte Carlo Simulation-Based Calculations of Complex DNA Damage for Incidents of Environmental Ionizing Radiation Exposure.

Authors: Kalospyros, Spyridon A.¹, spkals@central.ntua.gr, Gika, Violeta¹, guika@mail.ntua.gr, Nikitaki, Zacharenia¹, znikitaki@mail.ntua.gr, Kalamara, Antigoni¹, antigonikalamara@gmail.com, Kyriakou, Ioanna², ikyriak@uoi.gr, Emfietzoglou, Dimitris², demfietz@uoi.gr, Kokkoris, Michael¹, kokkoris@central.ntua.gr, Georgakilas, Alexandros G.¹, alexg@mail.ntua.gr

Source: Applied Sciences (2076-3417); Oct2021, Vol. 11 Issue 19, p8985, 21p

Non-targeted radiation effects in vivo: A critical glance of the future in radiobiology

Authors: Hatzi, Vasiliki I., Laskaratou, Danae A., Mavragani, Ifigeneia V., Nikitaki, Zacharenia, Mangelis, Anastasios, Panayiotidis, Mihalis I., Pantelias, Gabriel E., Terzoudi, Georgia I., Georgakilas, Alexandros G.

Source: In Cancer Letters 1 January 2015 356(1):34-42

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)

Authors: Nikitaki, Zacharenia, Nikolov, Vladimir, Mavragani, Ifigeneia V., Mladenov, Emil, Mangelis, Anastasios, Laskaratou, Danae A., Fragkoulis, Georgios I., Hellweg, Christine E., Martin, Olga A., Emfietzoglou, Dimitris, Hatzi, Vasiliki I., Terzoudi, Georgia I., Iliakis, George, Georgakilas, Alexandros G.

Source: Free radical research. 50:S64-S78

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105365355.0x000001&indx=1&recIds=ETOCvdc_100105365355.0x000001

Systemic mechanisms and effects of ionizing radiation: A new ‘old’ paradigm of how the bystanders and distant can become the players

Authors: Nikitaki, Zacharenia, Mavragani, Ifigeneia V., Laskaratou, Danae A., Gika, Violeta, Moskvin, Vadim P., Theofilatos, Konstantinos, Vougas, Konstantinos, Stewart, Robert D., Georgakilas, Alexandros G.

Source: Seminars in cancer biology. 37:77-95

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100031785912.0x000001&indx=1&recIds=ETOCvdc_100031785912.0x000001

Molecular inhibitors of DNA repair: searching for the ultimate tumor killing weapon

Authors: Nikitaki, Zacharenia, Michalopoulos, Ioannis, Georgakilas, Alexandros G

Source: Future medicinal chemistry. 7(12):1543-1558

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115568087.0x000001&indx=1&recIds=ETOCvdc_100115568087.0x000001

Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues.

Authors: Sagkrioti, Eftychia, Biz, Gökay Mehmet, Takan, Işıl, Asfa, Seyedehsadaf, Nikitaki, Zacharenia, Zanni, Vassiliki, Kars, Rumeysa Hanife, Hellweg, Christine E., Azzam, Edouard I., Logotheti, Stella, Pavlopoulou, Athanasia, Georgakilas, Alexandros G.

Source: Antioxidants; Nov2022, Vol. 11 Issue 11, p2286, 21p, 3 Diagrams, 2 Charts, 5 Graphs

Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis.

Authors: Mavragani, Ifigeneia V.¹ ifimav@mail.ntua.gr, Nikitaki, Zacharenia¹ znikitaki@mail.ntua.gr, Souli, Maria P.¹ mariasouli@mail.ntua.gr, Aziz, Asef² asefaziz@gmail.com, Nowsheen, Somaira^3,4 somairanowsheen@gmail.com, Aziz, Khaled³ aziz.khaled19@gmail.com, Rogakou, Emmy⁵ emmyrogakou@gmail.com, Georgakilas, Alexandros G.¹ alexg@mail.ntua.gr

Source: Cancers. Jul2017, Vol. 9 Issue 7, p91. 21p.

Bridging Plant and Human Radiation Response and DNA Repair through an In Silico Approach.

Authors: Nikitaki, Zacharenia¹ znikitaki@mail.ntua.gr, Pavlopoulou, Athanasia² athanasiapavlo@gmail.com, Holá, Marcela³ hola@ueb.cas.cz, Donà, Mattia⁴ mattia.dona@gmi.oeaw.ac.at, Michalopoulos, Ioannis⁵ imichalop@bioacademy.gr, Balestrazzi, Alma⁶ angelis@ueb.cas.cz, Angelis, Karel J.³ angelis@ueb.cas.cz, Georgakilas, Alexandros G.¹ alexg@mail.ntua.gr

Source: Cancers. Jun2017, Vol. 9 Issue 6, p65. 41p.

Subject Terms: *BIOMARKERS, *DNA, *GENES, *PLANTS, *RADIATION, *RADIATION measurements, *BIOINFORMATICS, *ENVIRONMENTAL exposure

Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair.

Authors: Nikitaki, Zacharenia, Velalopoulou, Anastasia, Zanni, Vassiliki, Tremi, Ioanna, Havaki, Sophia, Kokkoris, Michael, Gorgoulis, Vassilis G., Koumenis, Constantinos, Georgakilas, Alexandros G.

Source: Expert Reviews in Molecular Medicine; 2022, Vol. 24, p1-15, 15p

Subject Terms: BORON-neutron capture therapy, RADIOBIOLOGY, LINEAR energy transfer, RADIOTHERAPY, DNA damage, DNA repair

A Mathematical Radiobiological Model (MRM) to Predict Complex DNA Damage and Cell Survival for Ionizing Particle Radiations of Varying Quality.

Authors: Kalospyros, Spyridon A.¹ (AUTHOR) spkals@central.ntua.gr, Nikitaki, Zacharenia¹ (AUTHOR) znikitaki@mail.ntua.gr, Kyriakou, Ioanna² (AUTHOR) ikyriak@uoi.gr, Kokkoris, Michael¹ (AUTHOR) kokkoris@central.ntua.gr, Emfietzoglou, Dimitris² (AUTHOR) demfietz@uoi.gr, Georgakilas, Alexandros G.¹ (AUTHOR) alexg@mail.ntua.gr, Roca-Sanjuán, Daniel (AUTHOR), Lhiaubet-Vallet, Virginie L. (AUTHOR), Tuñón, Iñaki (AUTHOR), Correia, João D. G. (AUTHOR)

Source: Molecules. Feb2021, Vol. 26 Issue 4, p840-840. 1p.

Subject Terms: *IONIZING radiation, *DNA damage, *PHYSIOLOGICAL effects of radiation, *RADIATION protection, *MATHEMATICAL models, *ION sources

In Situ Detection of Complex DNA Damage Using Microscopy: A Rough Road Ahead.

Authors: Nikitaki, Zacharenia¹ (AUTHOR) znikitaki@mail.ntua.gr, Pariset, Eloise^2,3 (AUTHOR) eloise.pariset@nasa.gov, Sudar, Damir⁴ (AUTHOR) dsudar@qitissue.com, Costes, Sylvain V.² (AUTHOR) sylvain.v.costes@nasa.gov, Georgakilas, Alexandros G.¹ (AUTHOR) znikitaki@mail.ntua.gr

Source: Cancers. Nov2020, Vol. 12 Issue 11, p3288. 1p.

Subject Terms: *DNA, *MICROSCOPY, *RADIATION, *OXIDATIVE stress, *EARLY detection of cancer