Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF

Authors: Egle Kvedaraite, Magda Lourda, Natalia Mouratidou, Tim Düking, Avinash Padhi, Kirsten Moll, Paulo Czarnewski, Indranil Sinha, Ioanna Xagoraris, Efthymia Kokkinou, Anastasios Damdimopoulos, Whitney Weigel, Olga Hartwig, Telma E. Santos, Tea Soini, Aline Van Acker, Nelly Rahkonen, Malin Flodström Tullberg, Emma Ringqvist, Marcus Buggert, Carl Jorns, Ulrik Lindforss, Caroline Nordenvall, Christopher T. Stamper, David Unnersjö-Jess, Mira Akber, Ruta Nadisauskaite, Jessica Jansson, Niels Vandamme, Chiara Sorini, Marijke Elise Grundeken, Helena Rolandsdotter, George Rassidakis, Eduardo J. Villablanca, Maja Ideström, Stefan Eulitz, Henrik Arnell, Jenny Mjösberg, Jan-Inge Henter, Mattias Svensson

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4dc18c7a87ab47da922abb5a03ceaf68

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

Authors: Sandra Van Lint, Alexander Van Parys, Bram Van Den Eeckhout, Niels Vandamme, Stephane Plaisance, Annick Verhee, Dominiek Catteeuw, Elke Rogge, Jennifer De Geest, Nele Vanderroost, Jana Roels, Yvan Saeys, Gilles Uzé, Niko Kley, Anje Cauwels, Jan Tavernier

Source: Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)

Subject Terms: Type I Interferon, AcTakine, Tumor microenvironment, Cancer immunotherapy, Immune checkpoint, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/72e457857a534bb8861f2b6b4e37b51c

An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

Authors: Diede Houbaert, Apostolos Panagiotis Nikolakopoulos, Kathryn A. Jacobs, Odeta Meçe, Jana Roels, Gautam Shankar, Madhur Agrawal, Sanket More, Maarten Ganne, Kristine Rillaerts, Louis Boon, Magdalena Swoboda, Max Nobis, Larissa Mourao, Francesca Bosisio, Niels Vandamme, Gabriele Bergers, Colinda L.G.J. Scheele, Patrizia Agostinis

Source: Cell Reports, Vol 43, Iss 4, Pp 114020- (2024)

Subject Terms: CP: Immunology, CP: Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724003486; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/dca7f3404ac04b61a443f7d540320e6d

Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation

Authors: Marlies Boeren, Nicky de Vrij, My K. Ha, Sebastiaan Valkiers, Aisha Souquette, Sofie Gielis, Mariia Kuznetsova, Jolien Schippers, Esther Bartholomeus, Johan Van den Bergh, Nele Michels, Olivier Aerts, Julie Leysen, An Bervoets, Julien Lambert, Elke Leuridan, Johan Wens, Karin Peeters, Marie-Paule Emonds, George Elias, Niels Vandamme, Hilde Jansens, Wim Adriaensen, Arvid Suls, Stijn Vanhee, Niel Hens, Evelien Smits, Pierre Van Damme, Paul G. Thomas, Philippe Beutels, Peter Ponsaerts, Viggo Van Tendeloo, Peter Delputte, Kris Laukens, Pieter Meysman, Benson Ogunjimi

Source: Cell Reports, Vol 43, Iss 4, Pp 114062- (2024)

Subject Terms: CP: Immunology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724003905; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/0b4efad8a12a42feb58eab2d4fa7e411

Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation

Authors: Celine Everaert, Jasper Verwilt, Kimberly Verniers, Niels Vandamme, Alvaro Marcos Rubio, Jo Vandesompele, Pieter Mestdagh

Source: Biological Procedures Online, Vol 25, Iss 1, Pp 1-19 (2023)

Subject Terms: RNA sequencing, Oxford nanopore technologies, Single-cell RNA sequencing, Depletion, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1480-9222

Access URL: https://doaj.org/article/72d160ee571d4042a249a3fb72af33c7

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

Authors: Davide G. Franchina, Henry Kurniawan, Melanie Grusdat, Carole Binsfeld, Luana Guerra, Lynn Bonetti, Leticia Soriano-Baguet, Anouk Ewen, Takumi Kobayashi, Sophie Farinelle, Anna Rita Minafra, Niels Vandamme, Anaïs Carpentier, Felix K. Borgmann, Christian Jäger, Ying Chen, Markus Kleinewietfeld, Vasilis Vasiliou, Michel Mittelbronn, Karsten Hiller, Philipp A. Lang, Dirk Brenner

Source: Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/82e7256382b44500933f4d48afe4151d

MLKL deficiency in Braf V600E Pten −/− melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice

Authors: Sofie Martens, Nozomi Takahashi, Gillian Blancke, Niels Vandamme, Hanne Verschuere, Tatyana Divert, Marnik Vuylsteke, Geert Berx, Peter Vandenabeele

Source: Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/77587f1f6b4b4d57a3677719136c1aaf

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Authors: Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van den Hoecke, Isabelle Scheyltjens, Kiavash Movahedi, Hans Wils, Joke Reumers, Jeroen Van Houdt, Stein Aerts, Yvan Saeys

Source: Genome Biology, Vol 23, Iss 1, Pp 1-21 (2022)

Subject Terms: Hashing, scRNA-seq, MULTI-seq, CITE-seq, Sample multiplexing, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/70cb4b7c707e493b8f024717bdd552fa

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Authors: Esther Hoste, Kim Lecomte, Karl Annusver, Niels Vandamme, Jana Roels, Sophia Maschalidi, Lien Verboom, Hanna-Kaisa Vikkula, Mozes Sze, Lisette Van Hove, Kevin Verstaen, Arne Martens, Tino Hochepied, Yvan Saeys, Kodi Ravichandran, Maria Kasper, Geert van Loo

Source: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8b051a56d99b49d783afe85a0b01f20a

Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

Authors: María Lasierra Losada, Melissa Pauler, Niels Vandamme, Steven Goossens, Geert Berx, Moritz Leppkes, Harald Schuhwerk, Simone Brabletz, Thomas Brabletz, Marc P. Stemmler

Source: Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/dbae4d353ea948558fa786d31edd44b7

Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

Authors: Bart Neyns, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/2/e001749.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/f3b73327b159432399d5c58c01682dd6

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

Authors: Nicolas Skrypek, Kenneth Bruneel, Cindy Vandewalle, Eva De Smedt, Bieke Soen, Nele Loret, Joachim Taminau, Steven Goossens, Niels Vandamme, Geert Berx

Source: Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)

Subject Terms: EMT, ZEB2, Epigenetic regulation, RAB25, SIRT1, DNMT, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13072-018-0239-4; https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/27c823b7a8fd41389602917b5e508baa

ZEB Proteins in Leukemia: Friends, Foes, or Friendly Foes?

Authors: Bieke Soen, Niels Vandamme, Geert Berx, Jürg Schwaller, Pieter Van Vlierberghe, Steven Goossens

Source: HemaSphere, Vol 2, Iss 3 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000043; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/c200be78caad4dfd8c5b065ceb5cbbc5

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange

Authors: Tim Pieters, author^{1, 2, 3, 4}, Lieven Haenebalcke, author^{1, 2}, Kenneth Bruneel, author^{1, 2, 4}, Niels Vandamme, author^{1, 2, 4}, Tino Hochepied, author^{1, 2}, Jolanda van Hengel, author⁵, Dagmar Wirth, author⁶, Geert Berx, author^{1, 2, 4}, Jody J. Haigh, author⁷, Frans van Roy, author^{1, 2, 4}, Steven Goossens, author^{1, 2, 3, 4}

Source: Journal of Visualized Experiments. (122)

Availability: http://www.jove.com/video/55575