The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis

Authors: Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre PA Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi

Source: EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2024-2042 (2024)

Subject Terms: Innate Immunity, ASC, Serum Amyloid A (SAA), Inflammation, Amyloidosis, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/361701b3ccf5457e8ccf997a37e06f01

Comparison of the PI-RADS 2.1 scoring system to PI-RADS 2.0: Impact on diagnostic accuracy and inter-reader agreement.

Authors: Andreas M Hötker, Christian Blüthgen, Niels J Rupp, Aurelia F Schneider, Daniel Eberli, Olivio F Donati

Source: PLoS ONE, Vol 15, Iss 10, p e0239975 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dc2fa44138b54ab5b8be862a6030f9b3

Ultra-fast biparametric MRI in prostate cancer assessment: Diagnostic performance and image quality compared to conventional multiparametric MRI

Authors: Antonia M. Pausch, Vivien Filleböck, Clara Elsner, Niels J. Rupp, Daniel Eberli, Andreas M. Hötker

Source: European Journal of Radiology Open, Vol 14, Iss , Pp 100635- (2025)

Subject Terms: Prostate cancer, Deep learning, Ultra-fast bpMRI, MpMRI, PI-RADS, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352047725000024; https://doaj.org/toc/2352-0477

Access URL: https://doaj.org/article/bf7c95e0790f459792ff973a3824a92b

Oxygen supply maps for hypoxic microenvironment visualization in prostate cancer

Authors: Niels J Rupp, Peter J Schuffler, Qing Zhong, Florian Falkner, Markus Rechsteiner, Jan H Ruschoff, Christian Fankhauser, Matthias Drach, Remo Largo, Mathias Tremp, Cedric Poyet, Tullio Sulser, Glen Kristiansen, Holger Moch, Joachim Buhmann, Michael Muntener, Peter J Wild

Source: Journal of Pathology Informatics, Vol 7, Iss 1, Pp 3-3 (2016)

Subject Terms: Hypoxia, pimonidazole, prostate cancer, Computer applications to medicine. Medical informatics, R858-859.7, Pathology, RB1-214

File Description: electronic resource

Relation: http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2016;volume=7;issue=1;spage=3;epage=3;aulast=Rupp; https://doaj.org/toc/2153-3539

Access URL: https://doaj.org/article/aa62d964297447b0842298b53727fec8

TMARKER: A free software toolkit for histopathological cell counting and staining estimation

Authors: Peter J Schüffler, Thomas J Fuchs, Cheng Soon Ong, Peter J Wild, Niels J Rupp, Joachim M Buhmann

Source: Journal of Pathology Informatics, Vol 4, Iss 2, Pp 2-2 (2013)

Subject Terms: Color deconvolution, pathology, nuclei detection, superpixel classification, segmentation staining estimation, Computer applications to medicine. Medical informatics, R858-859.7, Pathology, RB1-214

File Description: electronic resource

Relation: http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2013;volume=4;issue=2;spage=2;epage=2;aulast=Schüffler; https://doaj.org/toc/2153-3539

Access URL: https://doaj.org/article/b1869bfe173a406f99b85f94e00ce3fc

SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets

Authors: Sandra N. Freiberger, Muriel Brada, Christine Fritz, Sylvia Höller, Alexander Vogetseder, Milo Horcic, Michel Bihl, Michal Michal, Martin Lanzer, Martin Wartenberg, Urs Borner, Peter K. Bode, Martina A. Broglie, Tamara Rordorf, Grégoire B. Morand, Niels J. Rupp

Source: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 473-487 (2021)

Subject Terms: Salivary gland neoplasm, Biopsy, FNA, Molecular, Comprehensive, Testing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S147655862100018X; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/07d220f8e060469d809549e7e9a329cb

Convergent network effects along the axis of gene expression during prostate cancer progression

Authors: Konstantina Charmpi, Tiannan Guo, Qing Zhong, Ulrich Wagner, Rui Sun, Nora C. Toussaint, Christine E. Fritz, Chunhui Yuan, Hao Chen, Niels J. Rupp, Ailsa Christiansen, Dorothea Rutishauser, Jan H. Rüschoff, Christian Fankhauser, Karim Saba, Cedric Poyet, Thomas Hermanns, Kathrin Oehl, Ariane L. Moore, Christian Beisel, Laurence Calzone, Loredana Martignetti, Qiushi Zhang, Yi Zhu, María Rodríguez Martínez, Matteo Manica, Michael C. Haffner, Ruedi Aebersold, Peter J. Wild, Andreas Beyer

Source: Genome Biology, Vol 21, Iss 1, Pp 1-31 (2020)

Subject Terms: Molecular aberrations, Network effects, Prostate cancer, Proteogenomic analysis, Tumor heterogeneity, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/707dce3d6d5841db93fe381dce66b0c0

Impact of short‐term Dutasteride treatment on prostate‐specific membrane antigen expression in a mouse xenograft model

Authors: Benedikt Kranzbühler, Rosa Sousa, Lukas Prause, Irene A. Burger, Niels J. Rupp, Tullio Sulser, Souzan Salemi, Daniel Eberli

Source: Cancer Reports, Vol 4, Iss 6, Pp n/a-n/a (2021)

Subject Terms: Dutasteride, prostate cancer, prostate‐specific membrane antigen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2573-8348

Access URL: https://doaj.org/article/b226359b608b4e599f72171e15f13bf5

High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification

Authors: Yi Zhu, Tobias Weiss, Qiushi Zhang, Rui Sun, Bo Wang, Xiao Yi, Zhicheng Wu, Huanhuan Gao, Xue Cai, Guan Ruan, Tiansheng Zhu, Chao Xu, Sai Lou, Xiaoyan Yu, Ludovic Gillet, Peter Blattmann, Karim Saba, Christian D. Fankhauser, Michael B. Schmid, Dorothea Rutishauser, Jelena Ljubicic, Ailsa Christiansen, Christine Fritz, Niels J. Rupp, Cedric Poyet, Elisabeth Rushing, Michael Weller, Patrick Roth, Eugenia Haralambieva, Silvia Hofer, Chen Chen, Wolfram Jochum, Xiaofei Gao, Xiaodong Teng, Lirong Chen, Qing Zhong, Peter J. Wild, Ruedi Aebersold, Tiannan Guo

Source: Molecular Oncology, Vol 13, Iss 11, Pp 2305-2328 (2019)

Subject Terms: biomarker, FFPE, pressure cycling technology, proteome, SWATH, tumor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/d5ac540ae607488999e040459d781060

Value of an online PI-RADS v2.1 score calculator for assessment of prostate MRI

Authors: Borna K. Barth, Katharina Martini, Stephan M. Skawran, Florian A. Schmid, Niels J. Rupp, Laura Zuber, Olivio F. Donati

Source: European Journal of Radiology Open, Vol 8, Iss , Pp 100332- (2021)

Subject Terms: Prostate MRI, Prostate cancer, PI-RADS 2.1, Reporting software, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352047721000125; https://doaj.org/toc/2352-0477

Access URL: https://doaj.org/article/70ea387ecd3c4f02ad921fd447498f2a

MCAD-Deficiency with Severe Neonatal Onset, Fatal Outcome and Normal Acylcarnitine Profile

Authors: Ralph Fingerhut, Pascal Joset, Niels J. Rupp, Martin Girsberger, Susanna H.M. Sluka, Theresia Herget, Silvia Miranda Azzarello-Burri, Anita Rauch, Matthias Baumgartner

Source: International Journal of Neonatal Screening, Vol 3, Iss 3, p 21 (2017)

Subject Terms: medium-chain acyl-CoA dehydrogenase deficiency, MCADD, newborn screening, NBS, dried blood spots, DBS, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2409-515X/3/3/21; https://doaj.org/toc/2409-515X

Access URL: https://doaj.org/article/3b4b40d96819428986ac51387e5fe087

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Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy

Authors: Blaz Pavlovic, Konstantin Bräutigam, Florence Dartiguenave, Paul Martel, Arnas Rakauskas, Valérie Cesson, Markus Veit, Pascal Oechslin, Alexander Gu, Thomas Hermanns, Karim Saba, Cédric Poyet, Andreas M. Hötker, Niels J. Rupp, Massimo Valerio, Laurent Derré, Daniel Eberli, Irina Banzola

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: PSA, Prostate specific antigen, Prostate cancer, Prostate biopsy, mpMRI, PI-RADS score, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b6949f6ccd9044508a54959dcc3ab281

Outcome-oriented clinicopathological reappraisal of sinonasal adenoid cystic carcinoma with broad morphological spectrum and high MYB::NFIB prevalence

Authors: Tina Mauthe, Christian M. Meerwein, David Holzmann, Michael B. Soyka, Simon A. Mueller, Ulrike Held, Sandra N. Freiberger, Niels J. Rupp

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/10c03b67cd83471798656249c167303c

18 F-Choline-PET/CT for non-FDG-avid salivary gland cancer: a preliminary report

Authors: Gregoire B. Morand, Sevda Karimian, Niels J. Rupp, Martin W. Huellner

Source: EJNMMI Research, Vol 14, Iss 1, Pp 1-5 (2024)

Subject Terms: Salivary gland neoplasms, Fluorodeoxyglucose F18, Radiopharmaceuticals, Choline, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/caac3fdcce1542b2b5e6f8c9c9e6bd7b

MRI-based radiomics for predicting histology in malignant salivary gland tumors: methodology and 'proof of principle'

Authors: Zahra Khodabakhshi, Laura Motisi, Andrea Bink, Martina A. Broglie, Niels J. Rupp, Maximilian Fleischmann, Jens von der Grün, Matthias Guckenberger, Stephanie Tanadini-Lang, Panagiotis Balermpas

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/50509ccbea254b86b6892c48bca898ca

Sinonasal mucosal melanoma treatment response assessment to immune checkpoint inhibitors using hybrid positron emission tomography imaging

Authors: Alexander Maurer, Nathalie A. Gstrein, Florentia Dimitriou, Thomas Sartoretti, Jan A. Schaab, Esmée L. Looman, Panagiotis Balermpas, Niels J. Rupp, Sandra N. Freiberger, Michael B. Soyka, David Holzmann, Tina Mauthe, Simon A. Mueller, Stephan Beintner-Skawran, Michael Messerli, David Kenkel, Martin W. Huellner, Christian M. Meerwein

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/1d1284ddc7cd4abea9034f5e596f22a9

The Milan system for reporting salivary gland cytopathology—A single‐center study of 2156 cases

Authors: Giulia Tochtermann, Miriam Nowack, Cristina Hagen, Niels J. Rupp, Kristian Ikenberg, Martina A. Broglie, Francesca Saro, Daniela Lenggenhager, Peter K. Bode

Source: Cancer Medicine, Vol 12, Iss 11, Pp 12198-12207 (2023)

Subject Terms: cytology, fine‐needle aspiration (FNA), Milan system for reporting salivary gland cytopathology (MSRSGC), risk of malignancy (ROM), salivary gland tumors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/1a932862ff284d14ae937c5522ae6639

68Ga-PSMA-11 PET/MRI versus multiparametric MRI in men referred for prostate biopsy: primary tumour localization and interreader agreement

Authors: Daniela A. Ferraro, Andreas M. Hötker, Anton S. Becker, Iliana Mebert, Riccardo Laudicella, Anka Baltensperger, Niels J. Rupp, Jan H. Rueschoff, Julian Müller, Ashkan Mortezavi, Marcelo T. Sapienza, Daniel Eberli, Olivio F. Donati, Irene A. Burger

Source: European Journal of Hybrid Imaging, Vol 6, Iss 1, Pp 1-15 (2022)

Subject Terms: Biopsy guidance, PSMA PET, mpMRI, Targeted biopsy, Primary staging, Interreader agreement, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2510-3636

Access URL: https://doaj.org/article/dcbc85ce5c564f4690ca9b48418c5633

Peritoneal carcinomatosis of a cystic papillary renal cell carcinoma following intraoperative cyst rupture during partial nephrectomy: A case report and review of the literature

Authors: Nico C. Grossmann, Axel Mischo, Niels J. Rupp, Thomas Hermanns

Source: Current Problems in Cancer: Case Reports, Vol 8, Iss , Pp 100198- (2022)

Subject Terms: Peritoneal metastasis, Renal cell carcinoma, Cyst, Rupture, Partial nephrectomy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266662192200062X; https://doaj.org/toc/2666-6219

Access URL: https://doaj.org/article/d6567a338bae48779c541833f269ce34