Pembrolizumab plus chemotherapy in frontline treatment of advanced ovarian cancer: Clinical and translational results from a phase 2 trial

Authors: How, Jeffrey A. ^{1, 8, 10, ∗}, Dang, Minghao ^{2, 8}, Lee, Sanghoon ¹, Fellman, Bryan ³, Westin, Shannon N. ¹, Sood, Anil K. ¹, Fleming, Nicole D. ¹, Shafer, Aaron ¹, Yuan, Ying ³, Liu, Jinsong ⁴, Zhao, Li ², Celestino, Joseph ¹, Hajek, Richard ¹, Morgan, Margaret B. ⁵, Parra, Edwin R. ⁶, Laberiano Fernandez, Caddie D. ⁶, Arrechedera, Claudio A. ⁶, Solis Soto, Luisa Maren ⁶, Schmeler, Kathleen M. ¹, Nick, Alpa ⁷, Lu, Karen H. ¹, Coleman, Robert ⁷, Wang, Linghua ², Jazaeri, Amir A. ^{1, 9, ∗∗}

Source: In Med 10 January 2025 6(1)

Clinical analysis of pathologic complete responders in advanced-stage ovarian cancer

Authors: LaFargue, Christopher J., Handley, Katelyn F., Fleming, Nicole D., Nick, Alpa M., Chelariu-Raicu, Anca, Fellman, Bryan, Castellano, Tara, Ogasawara, Aiko, Hom-Tedla, Marianne, Blake, Erin A., da Costa, Alexandre A.B.A., Crim, Aleia K., Rauh-Hain, Alejandro, Westin, Shannon N., Coleman, Robert L., Matsuo, Koji, Baiocchi, Glauco, Hasegawa, Kosei, Moore, Kathleen, Sood, Anil K.

Source: Gynecologic oncology. 165(1):82-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161128476.0x000001&indx=1&recIds=ETOCvdc_100161128476.0x000001

Endothelial p130cas confers resistance to anti-angiogenesis therapy

Authors: Wen, Yunfei, Chelariu-Raicu, Anca, Umamaheswaran, Sujanitha, Nick, Alpa M., Stur, Elaine, Hanjra, Pahul, Jiang, Dahai, Jennings, Nicholas B., Chen, Xiuhui, Corvigno, Sara, Glassman, Deanna, Lopez-Berestein, Gabriel, Liu, Jinsong, Hung, Mien-Chie, Sood, Anil K.

Source: In Cell Reports 25 January 2022 38(4)

Dasatinib, paclitaxel, and carboplatin in women with advanced-stage or recurrent endometrial cancer: A pilot clinical and translational study

Authors: Coleman, Robert L., Hu, Wei, Soliman, Pamela, Nick, Alpa, Ramirez, Pedro T., Westin, Shannon N., Garcia, Michael E., Zhu, Zhifei, Palancia, Julieta, Fellman, Bryan M., Yuan, Ying, Ram, Prahlad, Bischoff, Farideh, Schmeler, Kathleen, Bodurka, Diane, Meyer, Larissa A., Sood, Anil K.

Source: In Gynecologic Oncology April 2021 161(1):104-112

Pathologic distribution at the time of interval tumor reductive surgery informs personalized surgery for high-grade ovarian cancer

Authors: Bailey, Courtney D ¹, Previs, Rebecca ², Fellman, Bryan M ³, Zaid, Tarrik ⁴, Huang, Marilyn ⁵, Brown, Alaina ⁶, Enbaya, Ahmed ⁴, Balakrishnan, Nyla ⁷, Broaddus, Russell R ⁸, Bodurka, Diane C ⁴, Soliman, Pamela ⁴, Fleming, Nicole D ⁴, Nick, Alpa ⁹, Sood, Anil K ⁴, Westin, Shannon Neville ^{4, *}

Source: In International Journal of Gynecological Cancer February 2021 31(2):232-237

A multicenter open-label randomized phase II trial of paclitaxel plus EP-100, a novel LHRH receptor-targeted, membrane-disrupting peptide, versus paclitaxel alone for refractory or recurrent ovarian cancer

Authors: Chelariu-Raicu, Anca, Nick, Alpa, Urban, Renata, Gordinier, Mary, Leuschner, Carola, Bavisotto, Linda, Molin, Graziela Zibetti Dal, Whisnant, John K., Coleman, Robert L.

Source: In Gynecologic Oncology February 2021 160(2):418-426

The role of neoadjuvant chemotherapy in the management of low-grade serous carcinoma of the ovary and peritoneum: Further evidence of relative chemoresistance

Authors: Cobb, Lauren P., Sun, Charlotte C., Iyer, Revathy, Nick, Alpa M., Fleming, Nicole D., Westin, Shannon N., Sood, Anil K., Wong, Kwong K., Silva, Elvio G., Gershenson, David M.

Source: In Gynecologic Oncology September 2020 158(3):653-658

Endothelial p130cas confers resistance to anti-angiogenesis therapy

Authors: Wen, Yunfei, Chelariu-Raicu, Anca, Umamaheswaran, Sujanitha, Nick, Alpa M., Stur, Elaine, Hanjra, Pahul, Jiang, Dahai, Jennings, Nicholas B., Chen, Xiuhui, Corvigno, Sara, Glassman, Deanna, Lopez-Berestein, Gabriel, Liu, Jinsong, Hung, Mien-Chie, Sood, Anil K.

Source: Cell reports. 42(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190067113.0x000001&indx=1&recIds=ETOCvdc_100190067113.0x000001

Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene expression

Authors: Ramondetta, Lois M., Hu, Wei, Thaker, Premal H., Urbauer, Diana L., Chisholm, Gary B., Westin, Shannon N., Sun, Yunjie, Ramirez, Pedro T., Fleming, Nicole, Sahai, Sunil K., Nick, Alpa M., Arevalo, Jesusa M.G., Dizon, Thomas, Coleman, Robert L., Cole, Steve W., Sood, Anil K.

Source: In Gynecologic Oncology September 2019 154(3):524-530

Comparison of patient reported symptom burden on an enhanced recovery after surgery (ERAS) care pathway in patients with ovarian cancer undergoing primary vs. interval tumor reductive surgery

Authors: Meyer, Larissa A., Shi, Qiuling, Lasala, Javier, Iniesta, Maria D., Lin, Huei Kai, Nick, Alpa M., Williams, Loretta, Sun, Charlotte, Wang, Xin Shelley, Lu, Karen H., Ramirez, Pedro T.

Source: In Gynecologic Oncology March 2019 152(3):501-508

Correction: Immune environment and antigen specificity of the T cell receptor repertoire of malignant ascites in ovarian cancer.

Authors: Yoshida-Court, Kyoko, Karpinets, Tatiana V., Mitra, Aparna, Solley, Travis N., Dorta-Estremera, Stephanie, Sims, Travis T., Delgado Medrano, Andrea Y., Alam, Molly B. El, Ahmed-Kaddar, Mustapha, Lynn, Erica J., Sastry, K. Jagannadha, Zhang, Jianhua, Futreal, Andrew, Nick, Alpa, Lu, Karen, Colbert, Lauren E., Klopp, Ann H.

Source: PLoS ONE; 11/22/2024, Vol. 19 Issue 11, p1-3, 3p

Subject Terms: ASCITIC fluids, OVARIAN cancer, CD8 antigen, PEPTIDES, CD4 antigen

Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer

Authors: Shuford, Stephen, Wilhelm, Christine, Rayner, Melissa, Elrod, Ashley, Millard, Melissa, Mattingly, Christina, Lotstein, Alina, Smith, Ashley, Guo, Qi Jin, O'Donnell, Lauren, Elder, Jeffrey, Puls, Larry, Weroha, S., Hou, Xiaonan, Zanfagnin, Valentina, Nick, Alpa, Stany, Michael, Maxwell, G., Conrads, Thomas, Sood, Anil, Orr, David, Holmes, Lillia M., Gevaert, Matthew, Crosswell, Howland, DesRochers, Teresa

Source: Scientific reports. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185667730.0x000001&indx=1&recIds=ETOCvdc_100185667730.0x000001

Laparoscopic Surgical Algorithm to Triage the Timing of Tumor Reductive Surgery in Advanced Ovarian Cancer

Authors: Fleming, Nicole D., Nick, Alpa M., Coleman, Robert L., Westin, Shannon N., Ramirez, Pedro T., Soliman, Pamela T., Fellman, Bryan, Meyer, Larissa A., Schmeler, Kathleen M., Lu, Karen H., Sood, Anil K.

Source: Obstetrics and gynecology. 132(3):545-554

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176151713.0x000001&indx=1&recIds=ETOCvdc_100176151713.0x000001

Effect of an Enhanced Recovery After Surgery Program on Opioid Use and Patient-Reported Outcomes

Authors: Meyer, Larissa A., Lasala, Javier, Iniesta, Maria D., Nick, Alpa M., Munsell, Mark F., Shi, Qiuling, Wang, Xin Shelley, Cain, Katherine E., Lu, Karen H., Ramirez, Pedro T.

Source: Obstetrics and gynecology. 132(2):281-290

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176151066.0x000001&indx=1&recIds=ETOCvdc_100176151066.0x000001

Lipid profile of platelets and platelet-derived microparticles in ovarian cancer

Authors: Hu, Qianghua, Wang, Miao, Cho, Min Soon, Wang, Chunyan, Nick, Alpa M., Thiagarajan, Perumal, Aung, Fleur M., Han, Xianlin, Sood, Anil K., Afshar-Kharghan, Vahid

Source: In BBA Clinical December 2016 6:76-81

Role of cervical cytology in surveillance after radical trachelectomy for cervical cancer

Authors: Brown, Alaina J., Shah, Jaimin S., Fleming, Nicole D., Nick, Alpa M., Soliman, Pamela T., Chisholm, Gary B., Schmeler, Kathleen M., Ramirez, Pedro T., Frumovitz, Michael

Source: In Gynecologic Oncology August 2016 142(2):283-285

Characteristics of 10-year survivors of high-grade serous ovarian carcinoma

Authors: Dao, Fanny, Schlappe, Brooke A., Tseng, Jill, Lester, Jenny, Nick, Alpa M., Lutgendorf, Susan K., McMeekin, Scott, Coleman, Robert L., Moore, Kathleen N., Karlan, Beth Y., Sood, Anil K., Levine, Douglas A.

Source: In Gynecologic Oncology May 2016 141(2):260-263

A call for new standard of care in perioperative gynecologic oncology practice: Impact of enhanced recovery after surgery (ERAS) programs

Authors: Miralpeix, Ester, Nick, Alpa M., Meyer, Larissa A., Cata, Juan, Lasala, Javier, Mena, Gabriel E., Gottumukkala, Vijaya, Iniesta-Donate, Maria, Salvo, Gloria, Ramirez, Pedro T.

Source: In Gynecologic Oncology May 2016 141(2):371-378

Prospective phase II trial of levonorgestrel intrauterine device: nonsurgical approach for complex atypical hyperplasia and early-stage endometrial cancer

Authors: Westin, Shannon N., Fellman, Bryan, Sun, Charlotte C., Broaddus, Russell R., Woodall, Misty L., Pal, Navdeep, Urbauer, Diana L., Ramondetta, Lois M., Schmeler, Kathleen M., Soliman, Pamela T., Fleming, Nicole D., Burzawa, Jennifer K., Nick, Alpa M., Milbourne, Andrea M., Yuan, Ying, Lu, Karen H., Bodurka, Diane C., Coleman, Robert L., Yates, Melinda S.

Source: In American Journal of Obstetrics and Gynecology February 2021 224(2):191-191

Erythropoietin Stimulates Tumor Growth via EphB4

Authors: Pradeep, Sunila, Huang, Jie, Mora, Edna M., Nick, Alpa M., Cho, Min Soon, Wu, Sherry Y., Noh, Kyunghee, Pecot, Chad V., Rupaimoole, Rajesha, Stein, Martin A., Brock, Stephan, Wen, Yunfei, Xiong, Chiyi, Gharpure, Kshipra, Hansen, Jean M., Nagaraja, Archana S., Previs, Rebecca A., Vivas-Mejia, Pablo, Han, Hee Dong, Hu, Wei, Mangala, Lingegowda S., Zand, Behrouz, Stagg, Loren J., Ladbury, John E., Ozpolat, Bulent, Alpay, S. Neslihan, Nishimura, Masato, Stone, Rebecca L., Matsuo, Koji, Armaiz-Peña, Guillermo N., Dalton, Heather J., Danes, Christopher, Goodman, Blake, Rodriguez-Aguayo, Cristian, Kruger, Carola, Schneider, Armin, Haghpeykar, Shyon, Jaladurgam, Padmavathi, Hung, Mien-Chie, Coleman, Robert L., Liu, Jinsong, Li, Chun, Urbauer, Diana, Lopez-Berestein, Gabriel, Jackson, David B., Sood, Anil K.

Source: In Cancer Cell 9 November 2015 28(5):610-622