Utility of factor D and other alternative complement factors as biomarkers in systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH)

Authors: Petrow, Eva, Feng, Changyong, Frazer-Abel, Ashley, Marangoni, Roberta Goncalves, Lutz, Katie, Nichols, William C., Holers, V. Michael, Ritchlin, Christopher, White, R. James, III, Korman, Benjamin D.

Source: In Seminars in Arthritis and Rheumatism December 2024 69

Equivalency of Multiple Biomarkers to Clinical Pulmonary Arterial Hypertension Survival Risk Models

Authors: Griffiths, Megan, Simpson, Catherine E., Yang, Jun, Vaidya, Dhananjay, Nies, Melanie K., Brandal, Stephanie, Damico, Rachel, Hassoun, Paul, Ivy, Dunbar D., Austin, Eric D., Pauciulo, Michael W., Lutz, Katie A., Martin, Lisa J., Rosenzweig, Erika B., Benza, Raymond L., Nichols, William C., Manlhiot, Cedric, Everett, Allen D.

Source: In Chest December 2024 166(6):1511-1531

Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity

Authors: Alotaibi, Mona, Shao, Junzhe, Pauciulo, Michael W., Nichols, William C., Hemnes, Anna R., Malhotra, Atul, Kim, Nick H., Yuan, Jason X.-J., Fernandes, Timothy, Kerr, Kim M., Alshawabkeh, Laith, Desai, Ankit A., Bujor, Andreea M., Lafyatis, Robert, Watrous, Jeramie D., Long, Tao, Cheng, Susan, Chan, Stephen Y., Jain, Mohit

Source: Chest. 163(1):204-215

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190050150.0x000001&indx=1&recIds=ETOCvdc_100190050150.0x000001

Defining the clinical validity of genes reported to cause pulmonary arterial hypertension

Authors: Callejo, Emily P., Day, Kristina M., Macaya, Daniela, Maldonado-Velez, Gabriel, Archer, Stephen L., Auckland, Kathryn, Austin, Eric D., Badagliacca, Roberto, Barberà, Joan-Albert, Belge, Catharina, Bogaard, Harm Jan, Bonnet, Sébastien, Boomars, Karin A., Boucherat, Olivier, Chakinala, Murali M., Condliffe, Robin, Damico, Rachel Lynn, Delcroix, Marion, Desai, Ankit A., Doboszynska, Anna, Elliott, C. Greg, Eyries, Melanie, Escribano Subías, Maria Pilar, Gall, Henning, Ghio, Stefano, Ghofrani, Ardeschir-Hossein, Grünig, Ekkehard, Hamid, Rizwan, Harbaum, Lars, Hassoun, Paul M., Hemnes, Anna R., Hinderhofer, Katrin, Howard, Luke S., Humbert, Marc, Kiely, David G., Langleben, David, Lawrie, Allan, Loyd, Jim E., Moledina, Shahin, Montani, David, Morrell, Nichols W., Nichols, William C., Olschewski, Andrea, Olschewski, Horst, Papa, Silvia, Pauciulo, Mike W., Provencher, Steve, Quarck, Rozenn, Rhodes, Christopher J., Scelsi, Laura, Seeger, Werner, Stewart, Duncan J., Sweatt, Andrew, Swietlik, Emilia M., Treacy, Carmen, Trembath, Richard C., Tura-Ceide, Olga, Vizza, Carmine Dario, Vonk Noordegraaf, Anton, Wilkins, Martin R., Zamanian, Roham T., Zateyshchikov, Dmitry, Welch, Carrie L., Aldred, Micheala A., Balachandar, Srimmitha, Dooijes, Dennis, Eichstaedt, Christina A., Gräf, Stefan, Houweling, Arjan C., Machado, Rajiv D., Pandya, Divya, Prapa, Matina, Shaukat, Memoona, Southgate, Laura, Tenorio-Castano, Jair, Chung, Wendy K.

Source: In Genetics in Medicine November 2023 25(11)

Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers

Authors: Pal, Gian, Mangone, Graziella, Hill, Emily J., Ouyang, Bichun, Liu, Yuanqing, Lythe, Vanessa, Ehrlich, Debra, Saunders‐Pullman, Rachel, Shanker, Vicki, Bressman, Susan, Alcalay, Roy N., Garcia, Priscilla, Marder, Karen S., Aasly, Jan, Mouradian, M. Maral, Link, Samantha, Rosenbaum, Marc, Anderson, Sharlet, Bernard, Bryan, Wilson, Robert, Stebbins, Glenn, Nichols, William C., Welter, Marie‐Laure, Sani, Sepehr, Afshari, Mitra, Verhagen, Leo, Bie, Rob M.A., Foltynie, Tom, Hall, Deborah, Corvol, Jean‐Christophe, Goetz, Christopher G.

Source: Annals of neurology. 91(3):424-435

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141279033.0x000001&indx=1&recIds=ETOCvdc_100141279033.0x000001

Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension

Authors: Harbaum, Lars, Rhodes, Christopher J., Wharton, John, Lawrie, Allan, Karnes, Jason H., Desai, Ankit A., Nichols, William C., Humbert, Marc, Montani, David, Girerd, Barbara

Source: American journal of respiratory and critical care medicine. 205(12):1449-1460

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629557269&indx=1&recIds=ETOCRN629557269

Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension

Authors: Griffiths, Megan, Yang, Jun, Vaidya, Dhananjay, Nies, Melanie, Brandal, Stephanie, Ivy, D. Dunbar, Hickey, Francis, Wolter-Warmerdam, Kristine, Austin, Eric D., Mullen, Mary, Pauciulo, Michael W., Lutz, Katie A., Rosenzweig, Erika B., Hirsch, Russel, Yung, Delphine, Nichols, William C., Everett, Allen D.

Source: In The Journal of Pediatrics February 2022 241:68-76

ST2 Is a Biomarker of Pediatric Pulmonary Arterial Hypertension Severity and Clinical Worsening

Authors: Griffiths, Megan, Yang, Jun, Simpson, Catherine E., Vaidya, Dhananjay, Nies, Melanie, Brandal, Stephanie, Damico, Rachel, Ivy, D. Dunbar, Austin, Eric D., Pauciulo, Michael W., Lutz, Katie A., Rosenzweig, Erika B., Hirsch, Russel, Yung, Delphine, Nichols, William C., Everett, Allen D.

Source: In Chest July 2021 160(1):297-306

United States Pulmonary Hypertension Scientific Registry: Baseline Characteristics

Authors: Simms, Robert, Fortin, Terry, Safdar, Zeenat, Burger, Charles D., Frantz, Robert P., Hill, Nicholas S., Airhart, Sophia, Elwing, Jean, Simon, Marc, White, R. James, Robbins, Ivan M., Chakinala, Murali M., Badlam, Jessica B., Badesch, David B., Austin, Eric D., Benza, Raymond L., Chung, Wendy K., Farber, Harrison W., Feldkircher, Kathy, Frost, Adaani E., Poms, Abby D., Lutz, Katie A., Pauciulo, Michael W., Yu, Chang, Nichols, William C., Elliott, C. Gregory

Source: In Chest January 2021 159(1):311-327

United States Pulmonary Hypertension Scientific Registry

Authors: Badlam, Jessica B., Badesch, David B., Austin, Eric D., Benza, Raymond L., Chung, Wendy K., Farber, Harrison W., Feldkircher, Kathy, Frost, Adaani E., Poms, Abby D., Lutz, Katie A., Pauciulo, Michael W., Yu, Chang, Nichols, William C., Elliott, C. Gregory

Source: Chest. 159(1):311-327

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121116649.0x000001&indx=1&recIds=ETOCvdc_100121116649.0x000001

Elevated Interleukin-6 Levels Predict Clinical Worsening in Pediatric Pulmonary Arterial Hypertension

Authors: Chen, Jenny Y., Griffiths, Megan, Yang, Jun, Nies, Melanie K., Damico, Rachel L., Simpson, Catherine E., Vaidya, R. Dhananjay, Brandal, Stephanie, Ivy, D. Dunbar, Austin, Eric D., Nichols, William C., Pauciulo, Michael W., Lutz, Katie, Rosenzweig, Erika B., Hirsch, Russel, Yung, Delphine, Everett, Allen D.

Source: In The Journal of Pediatrics August 2020 223:164-169

Noninvasive Prognostic Biomarkers for Left-Sided Heart Failure as Predictors of Survival in Pulmonary Arterial Hypertension

Authors: Simpson, Catherine E., Damico, Rachel L., Hassoun, Paul M., Martin, Lisa J., Yang, Jun, Nies, Melanie K., Vaidya, R. Dhananjay, Brandal, Stephanie, Pauciulo, Michael W., Austin, Eric D., Ivy, D. Dunbar, Nichols, William C., Everett, Allen D.

Source: In Chest June 2020 157(6):1606-1616

RASA3 is a candidate gene in sickle cell disease‐associated pulmonary hypertension and pulmonary arterial hypertension

Authors: Prohaska, Clare C., Zhang, Xu, Schwantes‐An, Tae‐Hwi L., Stearman, Robert S., Hooker, Stanley, Kittles, Rick A., Aldred, Micheala A., Lutz, Katie A., Pauciulo, Michael W., Nichols, William C., Desai, Ankit A., Gordeuk, Victor R., Machado, Roberto F.

Source: Pulmonary circulation. 13(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195136009.0x000001&indx=1&recIds=ETOCvdc_100195136009.0x000001

Low‐affinity insulin‐like growth factor binding protein 7 and its association with pulmonary arterial hypertension severity and survival

Authors: Torres, Guillermo, Lancaster, Andrew C., Yang, Jun, Griffiths, Megan, Brandal, Stephanie, Damico, Rachel, Vaidya, Dhananjay, Simpson, Catherine E., Martin, Lisa J., Pauciulo, Michael W., Nichols, William C., Ivy, David D., Austin, Eric D., Hassoun, Paul M., Everett, Allen D.

Source: Pulmonary circulation. 13(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194671572.0x000001&indx=1&recIds=ETOCvdc_100194671572.0x000001

Insulin‐like growth factor binding Protein‐4: A novel indicator of pulmonary arterial hypertension severity and survival

Authors: Torres, Guillermo, Yang, Jun, Griffiths, Megan, Brandal, Stephanie, Damico, Rachel, Vaidya, Dhananjay, Simpson, Catherine E., Pauciulo, Michael W., Nichols, William C., Ivy, David D., Austin, Eric D., Hassoun, Paul M., Everett, Allen D.

Source: Pulmonary circulation. 13(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194670747.0x000001&indx=1&recIds=ETOCvdc_100194670747.0x000001

Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension

Authors: Hong, Jason, Medzikovic, Lejla, Sun, Wasila, Wong, Brenda, Ruffenach, Grégoire, Rhodes, Christopher J., Brownstein, Adam, Liang, Lloyd L., Aryan, Laila, Li, Min, Vadgama, Arjun, Kurt, Zeyneb, Schwantes-An, Tae-Hwi, Mickler, Elizabeth A., Gräf, Stefan, Eyries, Mélanie, Lutz, Katie A., Pauciulo, Michael W., Trembath, Richard C., Perros, Frédéric, Montani, David, Morrell, Nicholas W., Soubrier, Florent, Wilkins, Martin R., Nichols, William C., Aldred, Micheala A., Desai, Ankit A., Trégouët, David-Alexandre, Umar, Soban, Saggar, Rajan, Channick, Richard, Tuder, Rubin M., Geraci, Mark W., Stearman, Robert S., Yang, Xia, Eghbali, Mansoureh

Source: Circulation (Ovid); October 2024, Vol. 150 Issue: 16 p1268-1287, 20p

A novel BMPR2 mutation with widely disparate heritable pulmonary arterial hypertension clinical phenotype

Authors: Oriaku, Ifeoma, LeSieur, Mallory N., Nichols, William C., Barrios, Roberto, Elliott, C. Gregory, Frost, Adaani

Source: Pulmonary circulation. 10(3):1-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138771703.0x000001&indx=1&recIds=ETOCvdc_100138771703.0x000001

Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension

Authors: Potus, François, Pauciulo, Michael W., Cook, Elina K., Zhu, Na, Hsieh, Alexander, Welch, Carrie L., Shen, Yufeng, Tian, Lian, Lima, Patricia, Mewburn, Jeffrey, D'Arsigny, Christine L., Lutz, Katie A., Coleman, Anna W., Damico, Rachel, Snetsinger, Brooke, Martin, Ashley Y., Hassoun, Paul M., Nichols, William C., Chung, Wendy K., Rauh, Michael J., Archer, Stephen L.

Source: Circulation. 141(24):1986-2000

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188866558.0x000001&indx=1&recIds=ETOCvdc_100188866558.0x000001

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

Authors: Rhodes, Christopher J, Batai, Ken, Bleda, Marta, Haimel, Matthias, Southgate, Laura, Germain, Marine, Pauciulo, Michael W, Hadinnapola, Charaka, Aman, Jurjan, Girerd, Barbara, Arora, Amit, Knight, Jo, Hanscombe, Ken B, Karnes, Jason H, Kaakinen, Marika, Gall, Henning, Ulrich, Anna, Harbaum, Lars, Cebola, Inês, Ferrer, Jorge, Lutz, Katie, Swietlik, Emilia M, Ahmad, Ferhaan, Amouyel, Philippe, Archer, Stephen L, Argula, Rahul, Austin, Eric D, Badesch, David, Bakshi, Sahil, Barnett, Christopher, Benza, Raymond, Bhatt, Nitin, Bogaard, Harm J, Burger, Charles D, Chakinala, Murali, Church, Colin, Coghlan, John G, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Debette, Stéphanie, Elliott, C Gregory, Elwing, Jean, Eyries, Melanie, Fortin, Terry, Franke, Andre, Frantz, Robert P, Frost, Adaani, Garcia, Joe G N, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Harley, John, He, Hua, Hill, Nicholas S, Hirsch, Russel, Houweling, Arjan C, Howard, Luke S, Ivy, Dunbar, Kiely, David G, Klinger, James, Kovacs, Gabor, Lahm, Tim, Laudes, Matthias, Machado, Rajiv D, MacKenzie Ross, Robert V, Marsolo, Keith, Martin, Lisa J, Moledina, Shahin, Montani, David, Nathan, Steven D, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Oudiz, Ronald J, Ouwehand, Willem H, Peacock, Andrew J, Pepke-Zaba, Joanna, Rehman, Zia, Robbins, Ivan, Roden, Dan M, Rosenzweig, Erika B, Saydain, Ghulam, Scelsi, Laura, Schilz, Robert, Seeger, Werner, Shaffer, Christian M, Simms, Robert W, Simon, Marc, Sitbon, Olivier, Suntharalingam, Jay, Tang, Haiyang, Tchourbanov, Alexander Y, Thenappan, Thenappan, Torres, Fernando, Toshner, Mark R, Treacy, Carmen M, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Walsworth, Anna K, Walter, Robert E, Wharton, John, White, R James, Wilt, Jeffrey, Wort, Stephen J, Yung, Delphine, Lawrie, Allan, Humbert, Marc, Soubrier, Florent, Trégouët, David-Alexandre, Prokopenko, Inga, Kittles, Richard, Gräf, Stefan, Nichols, William C, Trembath, Richard C, Desai, Ankit A, Morrell, Nicholas W, Wilkins, Martin R

Source: In The Lancet Respiratory Medicine March 2019 7(3):227-238

Tandem mass spectrometry assay of β-glucocerebrosidase activity in dried blood spots eliminates false positives detected in fluorescence assay

Authors: Wolf, Pavlina, Alcalay, Roy N., Liong, Christopher, Cullen, Emmaline, Pauciulo, Michael W., Nichols, William C., Gan-Or, Ziv, Chung, Wendy K., Faulkner, Tina, Bentis, Christopher, Pomponio, Robert J., Ma, Xiwen, Kate Zhang, X., Keutzer, Joan M., Oliva, Petra

Source: In Molecular Genetics and Metabolism February 2018 123(2):135-139