Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation

Authors: Alberto E. Lopez, Joshua Mayoral, Huaixin Zheng, Nicholas P. Cianciotto

Source: Microbiology Spectrum, Vol 13, Iss 1 (2025)

Subject Terms: Legionella pneumophila, RNA-Seq, iron acquisition, FeoB, T2SS, type II secretion, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/ebc44cbc0aed4eac894f2331eedcc785

The Legionella collagen-like protein employs a distinct binding mechanism for the recognition of host glycosaminoglycans

Authors: Saima Rehman, Anna Katarina Antonovic, Ian E. McIntire, Huaixin Zheng, Leanne Cleaver, Maria Baczynska, Carlton O. Adams, Theo Portlock, Katherine Richardson, Rosie Shaw, Alain Oregioni, Giulia Mastroianni, Sara B-M. Whittaker, Geoff Kelly, Christian D. Lorenz, Arianna Fornili, Nicholas P. Cianciotto, James A. Garnett

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/dc482835699a4915aefeb24d5457763d

Bactericidal effectors of the Stenotrophomonas maltophilia type IV secretion system: functional definition of the nuclease TfdA and structural determination of TfcB

Authors: Brandi L. Cobe, Supratim Dey, George Minasov, Nicole Inniss, Karla J. F. Satchell, Nicholas P. Cianciotto

Source: mBio, Vol 15, Iss 7 (2024)

Subject Terms: Stenotrophomonas maltophilia, T4SS, antibacterial effectors, interbacterial competition, bactericidal activity, GHH nuclease, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/f13e5ad2659c467c91ad0bbde944bfd9

Effectors of the Stenotrophomonas maltophilia Type IV Secretion System Mediate Killing of Clinical Isolates of Pseudomonas aeruginosa

Authors: Megan Y. Nas, Jeffrey Gabell, Nicholas P. Cianciotto

Source: mBio, Vol 12, Iss 3 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/11076c3f347c4b37b2b99a1949cfd2b8

Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System

Authors: Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. McIntire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James A. Garnett

Source: Frontiers in Molecular Biosciences, Vol 7 (2020)

Subject Terms: Legionella pneumophila, effector, type II secretion system, structure, dynamics, NttA, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmolb.2020.00112/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/80a9c622cdc743b4bd1fac2e9b093da5

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

Authors: Richard C. White, Felizza F. Gunderson, Jessica Y. Tyson, Katherine H. Richardson, Theo J. Portlock, James A. Garnett, Nicholas P. Cianciotto

Source: mBio, Vol 9, Iss 2 (2018)

Subject Terms: Acanthamoeba, acyltransferase, aminopeptidase, Legionella pneumophila, Legionnaires' disease, protease, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/d75fb773bfc340ef90dc4a00bcee3ceb

Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane

Authors: Hilary K. Truchan, Harry D. Christman, Richard C. White, Nakisha S. Rutledge, Nicholas P. Cianciotto

Source: mBio, Vol 8, Iss 3 (2017)

Subject Terms: Acanthamoeba, chitinase, galectin, Legionella pneumophila, Legionella-containing vacuole, macrophage, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/98adedf29ed347a8ace8ee383d6903ae

Template Secondary Structure Promotes Polymerase Jumping During PCR Amplification

Authors: V.K. Viswanathan, Kevin Krcmarik, Nicholas P. Cianciotto

Source: BioTechniques, Vol 27, Iss 3, Pp 508-511 (1999)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

Access URL: https://doaj.org/article/b99a9fea80a640d7af03b3c4153a6f8f

The CRISPR-Associated Gene cas2 of Legionella pneumophila Is Required for Intracellular Infection of Amoebae

Authors: Felizza F. Gunderson, Nicholas P. Cianciotto

Source: mBio, Vol 4, Iss 2 (2013)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b41b20d1f46242659759d27f35342e55

The Listeria monocytogenes ChiA Chitinase Enhances Virulence through Suppression of Host Innate Immunity

Authors: Swarnava Chaudhuri, Benjamin N. Gantner, Richard D. Ye, Nicholas P. Cianciotto, Nancy E. Freitag

Source: mBio, Vol 4, Iss 2 (2013)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/6f3df39f694e4ad1b08be711e308672c

Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide and the Toll-like Receptor 3 nucleic-acid sensor.

Authors: Lubov S Grigoryeva, Nicholas P Cianciotto

Source: PLoS Pathogens, Vol 17, Iss 7, p e1009781 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/88cc1ec2e96348969c4dbd448835e5c1

Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation.

Authors: Saima Rehman, Lubov S Grigoryeva, Katherine H Richardson, Paula Corsini, Richard C White, Rosie Shaw, Theo J Portlock, Benjamin Dorgan, Zeinab S Zanjani, Arianna Fornili, Nicholas P Cianciotto, James A Garnett

Source: PLoS Pathogens, Vol 16, Iss 5, p e1008342 (2020)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/5bca9aa67fb54fa39bc9a8df958e6add

Phenylalanine hydroxylase from Legionella pneumophila is a thermostable enzyme with a major functional role in pyomelanin synthesis.

Authors: Marte I Flydal, Christa H Chatfield, Huaixin Zheng, Felizza F Gunderson, Oscar Aubi, Nicholas P Cianciotto, Aurora Martinez

Source: PLoS ONE, Vol 7, Iss 9, p e46209 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3458870?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/50fa7691edb441d3bf9c67a3d710f60b

Legionella pneumophila persists within biofilms formed by Klebsiella pneumoniae, Flavobacterium sp., and Pseudomonas fluorescens under dynamic flow conditions.

Authors: Catherine R Stewart, Viraj Muthye, Nicholas P Cianciotto

Source: PLoS ONE, Vol 7, Iss 11, p e50560 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23185637/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b1d938aa6a584f96b1c8e9a899c3a3d3