Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma

Authors: Sommer, Cesar, Boldajipour, Bijan, Kuo, Tracy C., Bentley, Trevor, Sutton, Janette, Chen, Amy, Geng, Tao, Dong, Holly, Galetto, Roman, Valton, Julien, Pertel, Thomas, Juillerat, Alexandre, Gariboldi, Annabelle, Pascua, Edward, Brown, Colleen, Chin, Sherman M., Sai, Tao, Ni, Yajin, Duchateau, Philippe, Smith, Julianne, Rajpal, Arvind, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra J.

Source: In Molecular Therapy 5 June 2019 27(6):1126-1138

Method for reducing DNA impurities in viral compositions

Regulated nucleic acid expression system

NON-INTEGRATING LENTI/ADENO-ASSOCIATED VIRUS HYBRID VECTOR SYSTEM

Regulated nucleic acid expression system

Vector packaging cell line

ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells

Authors: Davis, Brian M., Humeau, Laurent, Slepushkin, Vladimir, Binder, Gwendolyn, Korshalla, Lauren, Ni, Yajin, Ogunjimi, E. Oluwakemi, Chang, Lan-Fei, Lu, Xiaobin, Dropulic, Boro ^*

Source: In Blood 15 July 2004 104(2):364-373

Overexpression of an epitope-tagged serotonin transporter in serotonin neurons of the dorsal raphe nucleus using a defective HSV-1 vector

Authors: Ni, Yajin ^*, Goldman, D, Hoffman, B, Brooks, P.J

Source: In Behavioural Brain Research 2003 138(2):133-143

Off-the-shelf AlloCAR T™ cells targeting BCMA for the treatment of multiple myeloma

Authors: Sommer, Cesar, Bentley, Trevor, Sutton, Janette, Heyen, Jonathan, Valton, Julien, Ni, Yajin, Justewicz, Dominic, Van Blarcom, Thomas, Smith, Julianne, Leonard, Mark, Sasu, Barbra

Source: Clinical lymphoma, myeloma & leukemia. 19(S):e24-e24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091003686.0x000001&indx=1&recIds=ETOCvdc_100091003686.0x000001

Studies on the structures and antigenic properties of rabies virus glycoprotein analogues produced in yeast cells

Authors: Sakamoto, Shin-ichi ^{a, *}, Ide, Toshio ^a, Tokiyoshi, Sachio ^a, Nakao, Junji ^a, Hamada, Fukusaburo ^a, Yamamoto, Michitaka ^a, Grosby, Jun Alonso ^b, Ni, Yajin ^c, Kawai, Akihiko ^c

Source: In Vaccine 1999 17(3):205-218

ALLO-715, an Allogeneic BCMA CAR T Therapy Possessing an Off-Switch for the Treatment of Multiple Myeloma

Authors: Sommer, Cesar ^*, Boldajipour, Bijan ^*, Valton, Julien ^*, Galetto, Roman ^*, Bentley, Trevor ^*, Sutton, Janette ^*, Ni, Yajin ^*, Leonard, Mark ^*, Van Blarcom, Thomas ^*, Smith, Julianne, Chaparro-Riggers, Javier ^*, Sasu, Barbra

Source: In Blood 29 November 2018 132 Supplement 1:591-591

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

Authors: Ni, Yajin, Sun, Susan, Oparaocha, Ibe, Humeau, Laurent, Davis, Brian, Cohen, Reuben, Binder, Gwendolyn, Chang, Yung-Nien, Slepushkin, Vladimir, Dropulic, Boro

Source: Journal of Gene Medicine; Jun2005, Vol. 7 Issue 6, p818-834, 17p

Regulatory Considerations for Novel Gene Therapy Products: A Review of the Process Leading to the First Clinical Lentiviral Vector

Authors: Manilla, Peter, Rebello, Tessio, Afable, Cathleen, Lu, Xiaobin, Slepushkin, Vladimir, Humeau, Laurent M., Schonely, Kathy, Ni, Yajin, Binder, Gwendolyn K., Levine, Bruce L., Macgregor, Rob-Roy, June, Carl H., Dropulic, Boro

Source: Human Gene Therapy; January 2005, Vol. 16 Issue: 1 p17-25, 9p

Mapping and Characterization of a Sequential Epitope on the Rabies Virus Glycoprotein Which Is Recognized by a Neutralizing Monoclonal Antibody, RG719

Authors: Ni, Yajin, Tominaga, Yuichi, Honda, Yoshikazu, Morimoto, Kinjiro, Sakamoto, Shin'ichi, Kawai, Akihiko

Source: Microbiology and Immunology; September 1995, Vol. 39 Issue: 9 p693-702, 10p

CD86 and CD54 Co-Expression on VSV-G Pseudotyped HIV-1 Based Vectors Improves Transduction and Activation of Human Primary CD4+ T Lymphocytes.

Authors: Paszkiet, Brian ^*, Worden, Andrew ^*, Ni, Yajin ^*, Bao, Saran ^*, Lemiale, Franck ^*, Dropulic, Boro ^*, Humeau, Laurent ^*

Source: In Blood 16 November 2004 104(11):1754-1754

990. Unexpected Immune Enhancement by Autologous Lentiviral Modified CD4 T Cells: Results from a Phase I Gene Transfer Trial of Lentiviral Vector-Modified T Cells Expressing Antisense Envelope

Authors: MacGregor, Rob R.¹, Levine, Bruce L.¹, Lu, Xiaobin², Humeau, Laurent M.², Rebello, Tessio², Manilla, Peter², Ni, Yajin², Binder, Gwendolyn K.², Carroll, Richard¹, Boyer, Jean¹, Bushman, Frederic¹, Slepushkin, Vladimir², Dropulic, Boro², June, Carl H.¹

Source: Molecular Therapy. Jun2005, Vol. 11, p382-383. 2p.

Subject Terms: *GENETIC transformation