Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria

Authors: Islam, Epshita A. ^b, Fegan, Jamie E. ^a, Zeppa, Joseph J. ^a, Ahn, Sang Kyun ^a, Ng, Dixon ^b, Currie, Elissa G. ^a, Lam, Jessica ^a, Moraes, Trevor F. ^b, Gray-Owen, Scott D. ^{a, ⁎}

Source: In Vaccine 27 February 2025 48

Rational selection of TbpB variants yields a bivalent vaccine with broad coverage against Neisseria gonorrhoeae.

Authors: Fegan, Jamie E., Islam, Epshita A., Curran, David M., Ng, Dixon, Au, Natalie Y. T., Currie, Elissa G., Zeppa, Joseph J., Lam, Jessica, Schryvers, Anthony B., Moraes, Trevor F., Gray-Owen, Scott D.

Source: NPJ Vaccines; 1/15/2025, Vol. 10 Issue 1, p1-14, 14p

88 Identification and characterization of a novel complement factor I-binding protein in Pasteurella multocida

Authors: Huong Nguyen, Quynh, Lai, Royce, Norris, Michael, Ng, Dixon, Lai, Christine, Shah, Megha, Moraes, Trevor

Source: Immunobiology. 228(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195973237.0x000001&indx=1&recIds=ETOCvdc_100195973237.0x000001

Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors

Authors: Ziemianowicz, Daniel S., Ng, Dixon, Schryvers, Anthony B., Schriemer, David C.

Source: Journal of proteome research. 18(3):934-946

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619448210&indx=1&recIds=ETOCRN619448210

Developing a PmSLP3-based vaccine formulation that provides robust long-lasting protection against hemorrhagic septicemia–causing serogroup B and E strains of Pasteurella multocida in cattle.

Authors: Fegan, Jamie E., Waeckerlin, Regula C., Tesfaw, Liyuwork, Islam, Epshita A., Deresse, Getaw, Dufera, Dawit, Assefa, Eyob, Woldemedhin, Wubet, Legesse, Abinet, Akalu, Mirtneh, Bayissa, Berecha, Quynh Huong Nguyen, Ng, Dixon, Sang Kyun Ahn, Schryvers, Anthony B., Tefera, Takele A., Moraes, Trevor F., Gray-Owen, Scott D.

Source: Frontiers in Immunology; 2024, p1-20, 20p

Subject Terms: PASTEURELLA multocida, VACCINE development, MENINGOCOCCAL infections, CATTLE, SEPSIS, ANIMAL species, DISEASE complications

Geographic Terms: ASIA, AFRICA

Are lactoferrin receptors in Gram-negative bacteria viable vaccine targets?

Authors: Chan, Clement, Andisi, Vahid F., Ng, Dixon, Ostan, Nick, Yunker, Warren K., Schryvers, Anthony B.

Source: BioMetals. 31(3):381-398

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127078067.0x000001&indx=1&recIds=ETOCvdc_100127078067.0x000001

Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida.

Authors: Islam, Epshita A.¹, Fegan, Jamie E.², Tefera, Takele A.³, Curran, David M.¹, Waeckerlin, Regula C.⁴, Ng, Dixon¹, Ahn, Sang Kyun², Lai, Chun Heng Royce^1,5, Nguyen, Quynh Huong¹, Shah, Megha¹, Tesfaw, Liyuwork³, Adamu, Kassaye³, Medhin, Wubet W.³, Legesse, Abinet³, Deresse, Getaw³, Getachew, Belayneh³, Rawlyk, Neil⁶, Evans, Brock⁶, Potter, Andrew⁶, Schryvers, Anthony B.⁴

Source: PLoS Pathogens; 3/24/2023, Vol. 18 Issue 3, p1-24, 24p

Zinc acquisition and its contribution to Klebsiella pneumoniae virulence.

Authors: Maunders, Eve A., Giles, Matthew W., Ganio, Katherine, Cunningham, Bliss A., Bennett-Wood, Vicki, Cole, Gregory B., Ng, Dixon, Lai, Christine C., Neville, Stephanie L., Moraes, Trevor F., McDevitt, Christopher A., Tan, Aimee

Source: Frontiers in Cellular & Infection Microbiology; 2024, p01-18, 18p

Subject Terms: KLEBSIELLA pneumoniae, ZINC, URINARY tract infections, RESPIRATORY infections, LUNG infections

Company/Entity: WORLD Health Organization

Crystal Structure of the Minor Pilin CofB, the Initiator of CFA/III Pilus Assembly in Enterotoxigenic Escherichia coli

Authors: Kolappan, Subramania, Ng, Dixon, Yang, Guixiang, Harn, Tony, Craig, Lisa

Source: In Journal of Biological Chemistry 23 October 2015 290(43):25805-25818

Dynamic players and intricate interactions: An integrated investigation of the Mla lipid transport system

Authors: Ng, Dixon, Moraes, Trevor F.

Source: In Journal of Biological Chemistry September 2023 299(9)

Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens.

Authors: Chan, Clement, Ng, Dixon, Fraser, Marie E., Schryvers, Anthony B.

Source: BioMetals; Jun2023, Vol. 36 Issue 3, p683-702, 20p

Apparatus for dispensing and identifying product in washrooms

APPARATUS FOR DISPENSING AND IDENTIFYING PRODUCT IN WASHROOMS

Methods and systems for supplier quality management

Apparatus for dispensing and identifying product in washrooms

The Vibrio cholerae Minor Pilin TcpB Initiates Assembly and Retraction of the Toxin-Coregulated Pilus.

Authors: Ng, Dixon¹, Harn, Tony¹, Altindal, Tuba¹, Kolappan, Subramania¹, Marles, Jarrad M.², Lala, Rajan³, Spielman, Ingrid³, Gao, Yang², Hauke, Caitlyn A.², Kovacikova, Gabriela², Verjee, Zia¹, Taylor, Ronald K.², Biais, Nicolas^3,4 nicolas@mechano-micro-biology.org, Craig, Lisa¹ licraig@sfu.ca

Source: PLoS Pathogens. 12/19/2016, Vol. 12 Issue 12, p1-31. 31p.

Subject Terms: *VIBRIO cholerae, *PILI (Microbiology), *BACTERIAL toxins, *PILIN (Bacterial proteins), *MOLECULAR microbiology

The Role of the Moraxella catarrhalis CopB Protein in Facilitating Iron Acquisition From Human Transferrin and Lactoferrin.

Authors: Chan, Clement, Ng, Dixon, Schryvers, Anthony B.

Source: Frontiers in Microbiology; 9/23/2021, Vol. 12, p1-16, 16p

Subject Terms: TRANSFERRIN, LACTOFERRIN, MORAXELLA catarrhalis, RESPIRATORY infections in children, IRON proteins, RESPIRATORY infections, CARRIER proteins

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Prevalence of Slam-dependent hemophilins in Gram-negative bacteria.

Authors: Shin, Hyejin Esther¹, Chuxi Pan¹, Curran, David M.¹, Bateman, Thomas J.¹, Chong, Derrick H. Y.¹, Ng, Dixon¹, Shah, Megha¹, Moraes, Trevor F.¹, trevor.moraes@utoronto.ca

Source: Journal of Bacteriology; Jun2024, Vol. 206 Issue 6, p1-1, 1p

Lactoferrin binding protein B – a bi-functional bacterial receptor protein.

Authors: Ostan, Nicholas K. H.¹, Yu, Rong-Hua¹, Ng, Dixon¹, Lai, Christine Chieh-Lin², Pogoutse, Anastassia K.², Sarpe, Vladimir³, Hepburn, Morgan³, Sheff, Joey⁴, Raval, Shaunak⁴, Schriemer, David C.³, schryver@ucalgary.ca, Moraes, Trevor F.², Schryvers, Anthony B.^1,3

Source: PLoS Pathogens; 3/3/2017, Vol. 13 Issue 3, p1-20, 20p